Abstract: The present invention relates to a composition for prevention or treatment of autoimmune neurological disorder, comprising nanoparticles (PLGA-siSTAT3) comprising STAT3-specific siRNA and a biodegradable polymer material, the present invention having confirmed that, in an EAE animal model, which is a multiple sclerosis or encephalomyelitis animal model, the PLGA-siSTAT3 reduces a clinical symptom index induced by EAE, and inhibits demyelination of the spinal cord. In addition, the present invention has been confirmed to block a STAT3 signaling pathway associated with EAE and thus reduce demyelination, and inhibit microglial and neuroglial expression. In addition, the present invention has been confirmed to inhibit the inflammatory factors iNOS, IL-1?, IL-6, TNF-?, and inhibit the expression of the inflammation-mediating enzyme COX-2 and the chemokines MIP-1?, RANTES.

Abstract: The present disclosure relates to a nickel-plated heat-treated steel sheet for a battery case having excellent corrosion resistance and a manufacturing method thereof. In one embodiment, the nickel-plated heat-treated steel sheet comprises a base steel sheet; and a nickel layer formed on at least one surface of the base steel sheet; wherein the nickel layer is laminated in two or more layers, and a unit weight sequentially decreases from the base steel sheet toward a surface of the nickel layer.

Abstract: The present disclosure relates to a high-strength nickel-plated heat-treated steel sheet for a battery case and a manufacturing method thereof. In one embodiment, the nickel-plated heat-treated steel sheet comprises a base steel sheet containing 0.002 to 0.05 wt % of carbon (C); a nickel layer formed on at least one surface of the base steel sheet; and a nickel-iron (Ni—Fe) diffusion layer formed between the base steel sheet and the nickel layer, wherein the nickel-plated heat-treated steel sheet is manufactured by subjecting a plated sheet, in which a nickel plating layer is formed on at least one surface of the base steel sheet, to an alloying heat treatment, and satisfies the condition of the following Equation 1. TS 2 - TS 1 ? 20 [ Equation ? 1 ] (In Equation 1, TS1 is the tensile strength (MPa) of the plated sheet, and TS2 is the tensile strength (MPa) of the nickel-plated heat-treated steel sheet.

Abstract: The present disclosure relates to a nickel plated steel sheet for a battery case having excellent corrosion resistance and a method for manufacturing the same. In one embodiment, the nickel plated steel sheet comprises: a base steel sheet; a nickel plating layer formed on one or more surfaces of the base steel sheet; and a nickel-iron (Ni—Fe) diffusion layer formed between the base steel sheet and the nickel plating layer; wherein the nickel plating layer and the nickel-iron (Ni—Fe) diffusion layer are formed by forming an electro-nickel plating layer on the base steel sheet and an electroless nickel plating layer on at least a portion of the surface of the electro-nickel plating layer, followed by heat treatment, and the nickel plating layer includes one or more co-deposited elements selected from phosphorus (P), boron (B), tungsten (W), cobalt (Co), molybdenum (Mo), and copper (Cu) on its surface.

Abstract: The present invention relates to a nickel-plated heat-treated steel sheet for a battery case with excellent surface corrosion resistance and conductivity. In an embodiment, the nickel-plated heat-treated steel sheet for a battery case includes: a base steel plate; a nickel layer with a thickness of 0.5 to 6 ?m, which is formed on one or more sides of the base steel plate; and a Ni—Fe diffusion layer formed between the base steel plate and the nickel layer, wherein the Ni—Fe diffusion layer includes 0.3 to 25 wt % of Ni, and the nickel layer has a surface contact resistance of 0.8 m? or less.

Abstract: Disclosed are an aluminum-coated blank, a manufacturing method thereof, and an apparatus for manufacturing the same. The blank includes two or more aluminum-coated steel sheets connected together by a joint, each of the steel sheets including: a base steel sheet including 0.01-0.5 wt % of carbon, 0.01-1.0 wt % of silicon, 0.5-3.0 wt % of manganese, greater than 0 but not greater than 0.05 wt % of phosphorus, greater than 0 but not greater than 0.01 wt % of sulfur, greater than 0 but not greater than 0.1 wt % of aluminum, greater than 0 but not greater than 0.001 wt % of nitrogen, and the balance of iron and other inevitable impurities; and a coating layer including aluminum and formed on at least one surface of the base steel sheet.

Abstract: The present invention relates to a nickel-plated heat-treated steel sheet for a battery case with excellent surface corrosion resistance and conductivity. In an embodiment, the nickel-plated heat-treated steel sheet for a battery case includes: a base steel plate; a nickel layer with a thickness of 0.5 to 6 ?m, which is formed on one or more sides of the base steel plate; and a Ni—Fe diffusion layer formed between the base steel plate and the nickel layer, wherein the Ni—Fe diffusion layer includes 0.3 to 25 wt % of Ni, and the nickel layer has a surface contact resistance of 0.8 m? or less.

Abstract: Disclosed are an aluminum-coated blank, a manufacturing method thereof, and an apparatus for manufacturing the same. The blank includes two or more aluminum-coated steel sheets connected together by a joint, each of the steel sheets including: a base steel sheet including 0.01-0.5 wt % of carbon, 0.01-1.0 wt % of silicon, 0.5-3.0 wt % of manganese, greater than 0 but not greater than 0.05 wt % of phosphorus, greater than 0 but not greater than 0.01 wt % of sulfur, greater than 0 but not greater than 0.1 wt % of aluminum, greater than 0 but not greater than 0.001 wt % of nitrogen, and the balance of iron and other inevitable impurities; and a coating layer including aluminum and formed on at least one surface of the base steel sheet.

Abstract: The present application relates to a method for producing a reassortant Reoviridae virus and a vector library for the same, and provides: a method for producing a reassortant Reoviridae virus by using a cell line into which an RNA polymerase is introduced and an expression vector library according to an aspect; a reassortant Reoviridae virus produced by the method; and an expression vector library for producing reassortant rotavirus.

Abstract: Disclosed are an aluminum-coated blank, a manufacturing method thereof, and an apparatus for manufacturing the same. The blank includes two or more aluminum-coated steel sheets connected together by a joint, each of the steel sheets including: a base steel sheet including 0.01-0.5 wt % of carbon, 0.01-1.0 wt % of silicon, 0.5-3.0 wt % of manganese, greater than 0 but not greater than 0.05 wt % of phosphorus, greater than 0 but not greater than 0.01 wt % of sulfur, greater than 0 but not greater than 0.1 wt % of aluminum, greater than 0 but not greater than 0.001 wt % of nitrogen, and the balance of iron and other inevitable impurities; and a coating layer including aluminum and formed on at least one surface of the base steel sheet.

Abstract: Disclosed are an aluminum-coated blank, a manufacturing method thereof, and an apparatus for manufacturing the same. The blank includes two or more aluminum-coated steel sheets connected together by a joint, each of the steel sheets including: a base steel sheet including 0.01-0.5 wt % of carbon, 0.01-1.0 wt % of silicon, 0.5-3.0 wt % of manganese, greater than 0 but not greater than 0.05 wt % of phosphorus, greater than 0 but not greater than 0.01 wt % of sulfur, greater than 0 but not greater than 0.1 wt % of aluminum, greater than 0 but not greater than 0.001 wt % of nitrogen, and the balance of iron and other inevitable impurities; and a coating layer including aluminum and formed on at least one surface of the base steel sheet.

Abstract: Disclosed are an aluminum-coated blank, a manufacturing method thereof, and an apparatus for manufacturing the same. The blank includes two or more aluminum-coated steel sheets connected together by a joint, each of the steel sheets including: a base steel sheet including 0.01-0.5 wt % of carbon, 0.01-1.0 wt % of silicon, 0.5-3.0 wt % of manganese, greater than 0 but not greater than 0.05 wt % of phosphorus, greater than 0 but not greater than 0.01 wt % of sulfur, greater than 0 but not greater than 0.1 wt % of aluminum, greater than 0 but not greater than 0.001 wt % of nitrogen, and the balance of iron and other inevitable impurities; and a coating layer including aluminum and formed on at least one surface of the base steel sheet.

Abstract: Nickel-plated stainless steel sheets and a method of manufacturing the same are provided. Each of the nickel-plated stainless steel sheets includes a stainless steel base plate and a nickel plating layer formed on at least one surface of the stainless steel base plate by electroplating, in which the nickel plating layer includes a strike plating layer and a main plating layer which are sequentially laminated on the one surface of the stainless steel base plate.

Abstract: A method of preparing a nickel-plated heat-treated steel sheet having excellent workability. The method includes the steps of forming a nickel layer by electroplating at least one surface of a base steel sheet with nickel (Ni); and forming a nickel-iron (Ni-Fe) alloy layer between the base steel sheet and the nickel layer through diffusion heat treatment of the base steel sheet and the nickel layer. The nickel-plated heat-treated steel sheet has a superficial Rockwell hardness of 52 to 62.

Abstract: The present invention provides a nickel-plated and thermally-treated steel sheet with excellent corrosion resistance, in which a remaining nickel amount obtained by analyzing an nickel-iron alloy layer using energy dispersive spectrometry (EDS) or electron probe X-ray microanalysis (EPMA) after pure nickel remaining on the nickel-iron alloy layer was completely removed after the heat treatment for alloying of a nickel plated layer with base iron is 0.1 wt % or more to less than 30 wt % of the total amount of iron and nickel.

Abstract: The present invention provides a nickel-plated stainless steel sheet and a method of manufacturing the same. In one embodiment, the nickel-plated stainless steel sheet includes: a stainless steel base plate; and a nickel (Ni) plating layer formed on at least one surface of the steel base plate by electroplating, and the nickel plating layer includes a strike plating layer and a main plating layer which are sequentially laminated on the one surface of the steel base plate.

Abstract: A nickel-plated heat-treated steel sheet having excellent workability and a method of manufacturing the same. The nickel-plated heat-treated steel sheet includes: a base steel sheet; a nickel layer formed on one or both surfaces of the base steel sheet; and a nickel-iron (Ni—Fe) alloy layer formed between the base steel sheet and the nickel layer, and has a superficial Rockwell hardness of about 52 to about 62.

Abstract: The present disclosure provides a rotaxane polymer binder containing a polymer based on a rotaxane structure. The polymer binder may further contain a polymer cross-linked with a polar polymer. The polar polymer may be a polymer containing the element F, O or N in a functional group and having high polarity. In addition, the present disclosure provides an electrode containing the rotaxane polymer binder as a binder for a lithium secondary battery, and a secondary battery containing the electrode.

Abstract: Disclosed are an aluminum-coated blank, a manufacturing method thereof, and an apparatus for manufacturing the same. The blank includes two or more aluminum-coated steel sheets connected together by a joint, each of the steel sheets including: a base steel sheet including 0.01-0.5 wt % of carbon, 0.01-1.0 wt % of silicon, 0.5-3.0 wt % of manganese, greater than 0 but not greater than 0.05 wt % of phosphorus, greater than 0 but not greater than 0.01 wt % of sulfur, greater than 0 but not greater than 0.1 wt % of aluminum, greater than 0 but not greater than 0.001 wt % of nitrogen, and the balance of iron and other inevitable impurities; and a coating layer including aluminum and formed on at least one surface of the base steel sheet.

Abstract: The present invention provides a nickel-plated and thermally-treated steel sheet with excellent corrosion resistance, in which a remaining nickel amount obtained by analyzing an nickel-iron alloy layer using energy dispersive spectrometry (EDS) or electron probe X-ray microanalysis (EPMA) after pure nickel remaining on the nickel-iron alloy layer was completely removed after the heat treatment for alloying of a nickel plated layer with base iron is 0.1 wt % or more to less than 30 wt % of the total amount of iron and nickel.