Patents by Inventor Takafumi Tsuboi

Takafumi Tsuboi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vaccines for blocking transmission of
    Patent number: 7407658
    Abstract: The present invention relates novel methods and compositions for blocking transmission of Plasmodium vivax which cause malaria. In particular, Pvs25 and Pvs28 polypeptides, variants, including deglycosylated forms, and fusion proteins thereof, are disclosed which, when administered to a susceptible organism, induce an immune response against a 25 kD and 28 kD protein, respectively, on the surface of Plasmodium vivax zygotes and ookinetes. This immune response in the susceptible organism can block transmission of malaria.
    Type: Grant
    Filed: December 15, 2006
    Date of Patent: August 5, 2008
    Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
    Inventors: David C. Kaslow, Takafumi Tsuboi, Motomi Torii
  • VACCINES FOR BLOCKING TRANSMISSION OF PLASMODIUM VIVAX
    Publication number: 20070110772
    Abstract: The present invention relates novel methods and compositions for blocking transmission of Plasmodium vivax which cause malaria. In particular, Pvs25 and Pvs28 polypeptides, variants, including deglycosylated forms, and fusion proteins thereof, are disclosed which, when administered to a susceptible organism, induce an immune response against a 25 kD and 28 kD protein, respectively, on the surface of Plasmodium vivax zygotes and ookinetes. This immune response in the susceptible organism can block transmission of malaria.
    Type: Application
    Filed: December 15, 2006
    Publication date: May 17, 2007
    Applicant: The Govt. of the U.S.A. as represented by the Sec. of the Dept. of Health and Human Services
    Inventors: David Kaslow, Takafumi Tsuboi, Motomi Torii
  • Vaccines for blocking transmission of
    Patent number: 7192934
    Abstract: The present invention relates to novel methods and compositions for blocking transmission of Plasmodium vivax which cause malaria. In particular, Pvs25 and Pvs28 polypeptides, variants, including deglycosylated forms, and fusion proteins thereof, are disclosed which, when administered to a susceptible organism, induce an immune response against a 25 kD and 28 kD protein, respectively, on the surface of Plasmodium vivax zygotes and ookinetes. This immune response in the susceptible organism can block transmission of malaria.
    Type: Grant
    Filed: December 4, 1998
    Date of Patent: March 20, 2007
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: David C. Kaslow, Takafumi Tsuboi, Motomi Torii
  • Process for producing antigenic substance
    Publication number: 20060233789
    Abstract: An object of the present invention is to provide a means for producing an antigenic component with the retained native antigenicity using a cell-free protein synthesis. In particular, it is an object to provide a means for producing an antigenic component without depending on codon usage, like expressing an antigenic component from a gene containing a large amount of AT. The present inventors have made a strenuous study to solve the matters described above and successfully completed the present invention by preparing an antigenic component with the retained antigenicity, in particular a malaria antigen useful for manufacturing a malaria vaccine, through a system with the use of a wheat embryo among cell-free protein synthesis means.
    Type: Application
    Filed: September 24, 2004
    Publication date: October 19, 2006
    Applicant: CellFree Science Co., Ltd.
    Inventors: Yaeta Endo, Takafumi Tsuboi, Motomi Torii, Tatsuya Sawasaki