Patents by Inventor Takahiro Fujiwara
Takahiro Fujiwara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8658815Abstract: The present invention provides a method for inexpensively producing di-?-chloro-bis[chloro(?6-1-isopropyl-4-methylbenzene)ruthenium (II)] complex used as a catalyst raw material for a hydrogenation or metathesis polymerization reaction at a high yield. In the present invention, the above-described problem can be solved by reacting ruthenium chloride or a hydrate thereof with ?-terpinene in a solvent. In particular, by using an alcohol having a boiling point of 100° C. or higher as a solvent, the yield of the above-described complex can be increased.Type: GrantFiled: March 18, 2010Date of Patent: February 25, 2014Assignee: Takasago International CorporationInventors: Takahiro Fujiwara, Hideki Nara
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Patent number: 8551908Abstract: An exhaust gas purification catalyst includes: a lower catalyst layer that contains a ceria-zirconia mixed oxide having 50 to 70 mass % of CeO2 and 5 mass % or more of Pr2O3 and carries at least one of Pt and Pd; and an upper catalyst layer that contains at least zirconia and carries at least Rh, wherein the total amount of CeO2 per liter of the carrier base is 15 to 30 g. Because the amount of CeO2 is small, formation of H2S is suppressed and a high capability of adsorbing and releasing oxygen is brought out in spite of the small amount of CeO2.Type: GrantFiled: June 26, 2009Date of Patent: October 8, 2013Assignee: Toyota Jidosha Kabushiki KaishaInventors: Akemi Satou, Masahiko Takeuchi, Keizo Hiraku, Yusuke Kawamura, Takahiro Fujiwara, Tadashi Suzuki, Naoki Takahashi
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Patent number: 8552204Abstract: Disclosed is a novel zinc cluster compound represented by general formula (1): Zn4O (OCOR)6 (RCOOH)n, wherein R represents an alkyl group which has 1 to 4 carbon atoms and may be substituted with a halogen atom, and n represents 0.1 to 1, and also disclosed are a method for producing the compound and a reaction using the compound.Type: GrantFiled: May 31, 2010Date of Patent: October 8, 2013Assignee: Takasago International CorporationInventors: Yoshimasa Matsushima, Hideki Nara, Takahiro Fujiwara
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Publication number: 20120309937Abstract: Provided are peptides imparting cell permeability to a lipid membrane structure and/or enhancing the cell permeability of a lipid membrane structure, and a lipid membrane structure which comprises, as a constituent lipid, a lipid bound to such a peptide and has cell permeability or shows enhanced cell permeability. The amino acid sequences of the peptides imparting cell permeability to a lipid membrane structure and/or enhancing the cell permeability of a lipid membrane structure are represented by: LX1X2X1X1X1L, LLX2X1X1X1L and LX1X2X1X1L (wherein L represents a leucine residue; X1 represents a polar amino acid residue; and X2 represents a polar, non-charged and branched chain amino acid residue).Type: ApplicationFiled: December 14, 2010Publication date: December 6, 2012Applicant: NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITYInventors: Hideyoshi Harashima, Takahiro Fujiwara, Hidetaka Akita
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Patent number: 8241462Abstract: To provide a papermaking internal sizing agent capable of efficiently imparting sizing performance even in neutral papermaking which uses calcium carbonate as filler, and uses no aluminum sulfate or uses a small amount of aluminum sulfate, and also provide a paper or a paperboard obtained by using the papermaking internal sizing agent. The papermaking internal sizing agent comprises as an effective ingredient an amphoteric copolymer having hydrophobic groups and cationic groups, at least a part of the cationic groups being quaternized. Preferably, the amphoteric copolymer is obtained by polymerizing monomer ingredients that it essentially contain a hydrophobic monomer (A), a cationic monomer (B), and an anionic monomer (C) and that an anion equivalent of the monomer (C) is 0.1 to 90% of a cation equivalent of the monomer (B), in which a rate of quaternizing of the cationic groups is not less than 40% by mole. The paper or the paperboard contains the above papermaking internal sizing agent.Type: GrantFiled: March 6, 2008Date of Patent: August 14, 2012Assignees: Harima Chemicals, Inc., Nippon Paper Industries Co., Ltd.Inventors: Kazunari Sakai, Takahiro Fujiwara, Kazushige Inaoka, Takashi Yamaguchi, Masaki Ito, Yasunobu Ooka
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Publication number: 20120172601Abstract: Disclosed is a novel zinc cluster compound represented by general formula (1): Zn4O (OCOR)6 (RCOOH)n, wherein R represents an alkyl group which has 1 to 4 carbon atoms and may be substituted with a halogen atom, and n represents 0.1 to 1, and also disclosed are a method for producing the compound and a reaction using the compound.Type: ApplicationFiled: May 31, 2010Publication date: July 5, 2012Applicant: TAKASAGO INTERNATIONAL CORPORATIONInventors: Yoshimasa Matsushima, Hideki Nara, Takahiro Fujiwara
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Publication number: 20120016148Abstract: The present invention provides a method for inexpensively producing di-?-chloro-bis[chloro(?6-1-isopropyl-4-methylbenzene)ruthenium (II)] complex used as a catalyst raw material for a hydrogenation or metathesis polymerization reaction at a high yield. In the present invention, the above-described problem can be solved by reacting ruthenium chloride or a hydrate thereof with ?-terpinene in a solvent. In particular, by using an alcohol having a boiling point of 100° C. or higher as a solvent, the yield of the above-described complex can be increased.Type: ApplicationFiled: March 18, 2010Publication date: January 19, 2012Inventors: Takahiro Fujiwara, Hideki Nara
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Patent number: 7964744Abstract: Provided is a method for producing a ruthenium complex comprises the step of reacting a ruthenium compound represented by general formula (1): [RuX(L)(PP)]X??(1), wherein Ru represents a ruthenium atom; X represents a halogen atom; L represents an arene; and PP represents an optically active bisphosphine, with a carboxylate salt represented by general formula (2): R1CO2M??(2), wherein M represents a monovalent cation; and R1 represents a group selected from the group consisting of alkyl groups, haloalkyl groups, phenyl groups optionally having a substituent(s), 1-aminoalkyl groups and 1-amino-1-phenylalkyl groups, to produce a ruthenium complex represented by general formula (3): Ru(OCOR1)2(PP)??(3), wherein R1 represents the group selected from the group consisting of alkyl groups, haloalkyl groups, phenyl groups optionally having a substituent(s), 1-aminoalkyl groups and 1-amino-1-phenylalkyl groups; and PP represents the optically active bisphosphine.Type: GrantFiled: August 13, 2009Date of Patent: June 21, 2011Assignee: Takasago International CorporationInventors: Hideki Nara, Noboru Sayo, Takahiro Fujiwara
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Publication number: 20110099987Abstract: An exhaust gas purification catalyst includes: a lower catalyst layer that contains a ceria-zirconia mixed oxide having 50 to 70 mass % of CeO2 and 5 mass % or more of Pr2O3 and carries at least one of Pt and Pd; and an upper catalyst layer that contains at least zirconia and carries at least Rh, wherein the total amount of CeO2 per liter of the carrier base is 15 to 30 g. Because the amount of CeO2 is small, formation of H2S is suppressed and a high capability of adsorbing and releasing oxygen is brought out in spite of the small amount of CeO2.Type: ApplicationFiled: June 26, 2009Publication date: May 5, 2011Inventors: Akemi Satou, Masahiko Takeuchi, Keizo Hiraku, Yusuki Kawamura, Takahiro Fujiwara, Tadashi Suzuki, Naoki Takahashi
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Patent number: 7880025Abstract: The present invention is to provide a ruthenium complex having a novel arene moiety, which has improved solubility in various solvents, and a method for production thereof. The present invention relates to a novel ruthenium complex having an arene moiety, which has a trisubstituted silyl group introduced to the arene moiety, and a method for production thereof.Type: GrantFiled: May 18, 2010Date of Patent: February 1, 2011Assignee: Takasago International CorporationInventors: Taichiro Touge, Hideki Nara, Takahiro Fujiwara
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Publication number: 20100298588Abstract: The present invention is to provide a ruthenium complex having a novel arene moiety, which has improved solubility in various solvents, and a method for production thereof. The present invention relates to a novel ruthenium complex having an arene moiety, which has a trisubstituted silyl group introduced to the arene moiety, and a method for production thereof.Type: ApplicationFiled: May 18, 2010Publication date: November 25, 2010Applicant: Takasago International CorporationInventors: Taichiro Touge, Hideki Nara, Takahiro Fujiwara
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Publication number: 20100200185Abstract: To provide a papermaking internal sizing agent capable of efficiently imparting sizing performance even in neutral papermaking which uses calcium carbonate as filler, and uses no aluminum sulfate or uses a small amount of aluminum sulfate, and also provide a paper or a paperboard obtained by using the papermaking internal sizing agent. The papermaking internal sizing agent comprises as an effective ingredient an amphoteric copolymer having hydrophobic groups and cationic groups, at least a part of the cationic groups being quaternized. Preferably, the amphoteric copolymer is obtained by polymerizing monomer ingredients that it essentially contain a hydrophobic monomer (A), a cationic monomer (B), and an anionic monomer (C) and that an anion equivalent of the monomer (C) is 0.1 to 90% of a cation equivalent of the monomer (B), in which a rate of quaternizing of the cationic groups is not less than 40% by mole. The paper or the paperboard contains the above papermaking internal sizing agent.Type: ApplicationFiled: March 6, 2008Publication date: August 12, 2010Inventors: Kazunari Sakai, Takahiro Fujiwara, Kazushige Inaoka
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Publication number: 20100076210Abstract: Provided is a method for producing a ruthenium complex comprises the step of reacting a ruthenium compound represented by general formula (1): [RuX(L)(PP)]X ??(1), wherein Ru represents a ruthenium atom; X represents a halogen atom; L represents an arene; and PP represents an optically active bisphosphine, with a carboxylate salt represented by general formula (2): R1CO2M ??(2), wherein M represents a monovalent cation; and R1 represents a group selected from the group consisting of alkyl groups, haloalkyl groups, phenyl groups optionally having a substituent(s), 1-aminoalkyl groups and 1-amino-1-phenylalkyl groups, to produce a ruthenium complex represented by general formula (3): Ru(OCOR1)2(PP) ??(3), wherein R1 represents the group selected from the group consisting of alkyl groups, haloalkyl groups, phenyl groups optionally having a substituent(s), 1-aminoalkyl groups and 1-amino-1-phenylalkyl groups; and PP represents the optically active bisphosphine.Type: ApplicationFiled: August 13, 2009Publication date: March 25, 2010Applicant: TAKASAGO INTERNATIONAL CORPORATIONInventors: Hideki Nara, Noboru Sayo, Takahiro Fujiwara
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Patent number: 7312347Abstract: Provided is a method for producing an optically active compound, in more detail, for producing an optically active compound by asymmetric hydrogenation in a high yield and asymmetric yield. The present invention also provides a catalyst for asymmetric synthesis for the above production method, especially a catalyst for asymmetric hydrogenation, containing a transition metal complex. Further, the present invention provides a new diphosphine compound useful as a ligand of the above transition metal complex and a new transition metal complex containing the above diphosphine compound. The present invention relates to a diphosphine compound represented by the following formula (1): a transition metal complex using the compound, a catalyst for asymmetric synthesis comprising the above transition metal complex and a method for producing an optically active compound using the above catalyst for asymmetric synthesis.Type: GrantFiled: September 22, 2006Date of Patent: December 25, 2007Assignee: Takasago International CorporationInventors: Takahiro Fujiwara, Tohru Yokozawa
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Publication number: 20070208143Abstract: The present invention provides a method for preparing a water soluble polymer, which comprises: a first step of polymerizing: (a) 60 to 99.5 mol % of at least one selected from acrylamide and methacrylamide, (b) 0.5 to 20 mol % of at least one selected from ?,?-unsaturated monocarboxylic acid, ?,?-unsaturated dicarboxylic acid and salts thereof, and (c) 1 to 20 mol % of at least one selected from a water soluble cationic monomer and a salt thereof, (d) 0.01 to 1 mol % of a chain transfer agent, and (e) 0.005 to 5 mol % of a crosslinkable monomer, in the presence of a persulfate-based catalyst to obtain a prepolymer; and a second step of further adding the persulfate-based catalyst to the prepolymer obtained in the first step and the residual monomer, followed by the polymerization and termination of the polymerization.Type: ApplicationFiled: March 6, 2006Publication date: September 6, 2007Inventors: Yoshiharu Kimura, Takahiro Fujiwara
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Publication number: 20070142472Abstract: The present invention relates to a process for producing an optically active 3-(4-hydroxyphenyl)propionic acid useful as intermediates for medicines, through short steps in good yield and with high optical purity.Type: ApplicationFiled: November 26, 2004Publication date: June 21, 2007Inventors: Tohru Yokozawa, Hideo Shimizu, Takahiro Fujiwara, Yasunori Ino
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Publication number: 20070073065Abstract: Provided is a method for producing an optically active compound, in more detail, for producing an optically active compound by asymmetric hydrogenation in a high yield and asymmetric yield. The present invention also provides a catalyst for asymmetric synthesis for the above production method, especially a catalyst for asymmetric hydrogenation, containing a transition metal complex. Further, the present invention provides a new diphosphine compound useful as a ligand of the above transition metal complex and a new transition metal complex containing the above diphosphine compound. The present invention relates to a diphosphine compound represented by the following formula (1): a transition metal complex using the compound, a catalyst for asymmetric synthesis comprising the above transition metal complex and a method for producing an optically active compound using the above catalyst for asymmetric synthesis.Type: ApplicationFiled: September 22, 2006Publication date: March 29, 2007Applicant: Takasago International CorporationInventors: Takahiro Fujiwara, Tohru Yokozawa
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Patent number: 7038087Abstract: An object of the present invention is to provide a process for the production of an optically active amino alcohol, particularly an optically active amino alcohol of a trans-form, being excellent in economy and efficiency, and suitable for industry using easily available and less expensive materials. The present invention relates to a process for the production of an optically active amino alcohol comprising the steps that an optically active hydroxy ester in a trans-form obtained by an asymmetric hydrogenation of an easily available ?-keto ester is reacted with hydrazine, the resulting optically active hydrazinocarbonyl alcohol is subjected to a Curtius rearrangement in the presence of alcohol and protective group of amino group of the resulting optically active alkoxycarbonylamino alcohol is deprotected. As a result of the process for the production in accordance with the present invention, the objected substance is able to be prepared in a high optical purity and in a high yield.Type: GrantFiled: September 4, 2003Date of Patent: May 2, 2006Assignee: Takasago International CorporationInventors: Takahiro Fujiwara, Hideki Nara, Tsukasa Sotoguchi
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Patent number: 6912472Abstract: A method of detecting the location of a failure (e.g., a sudden leak) in a fluid pipeline network, which can be suitably used for estimation of the location of a failure in a water pipeline network, includes the steps of periodically measuring a flow rate or fluid pressure with sensors arranged at a plurality of measuring points along a pipeline in a water pipeline network; comparing a latest measured amount and a previous measured amount at each measuring point to determine if an amount of change at an arbitrary point has exceeded a predetermined value; and calculating a position at which an amount of change becomes maximum, the position being calculated from the magnitudes of the amounts of changes in respective measured values at the time of the detection. The pipeline network may be a water supply and distribution pipeline network which includes a trunk pipeline and branch pipelines.Type: GrantFiled: May 7, 2003Date of Patent: June 28, 2005Assignee: Enegene Co., Ltd.Inventors: Shizuo Mizushina, Atsushi Adachi, Takahiro Fujiwara
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Publication number: 20040093172Abstract: There is provided a method of detecting the location of a failure in a fluid feed pipeline network, which can be suitably used for estimation of the location of a failure in a water pipeline network. A method of estimating the location of an abnormality in a fluid feed pipeline network includes the steps of periodically measuring a flow rate or a fluid pressure of a fluid by each sensor arranged at a plurality of measuring points along a pipeline in a fluid feed pipeline network; comparing a latest measured amount and a previous measured amount at each measuring point to determine if an amount of change at an arbitrary point has exceeded a predetermined value; and calculating a position at which an amount of change becomes maximum, the position being calculated from the magnitudes of the amounts of changes in respective measured values at the time of the detection.Type: ApplicationFiled: May 7, 2003Publication date: May 13, 2004Applicant: Hamanen Co., Ltd.Inventors: Shizuo Mizushina, Atsushi Adachi, Takahiro Fujiwara