Patents by Inventor Takanori Okada

Takanori Okada has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4548146
    Abstract: There is disclosed a method of finishing lengthwise both ends of a towel fabric by sewing after automatically forming a three-ply part on each and, and an apparatus for practicing this method.At each end of the towel fabric, a first part and a second part to wrap up the first part are folded automatically in turn so as to form a three-ply part including the above two parts and a ground fabric part.Selvages extending outwardly slightly farther than crosswise both ends of the first and the second parts are formed on both ends of the ground fabric part of the three-ply part. The three-ply part thus provided with selvages is stitched from one selvage side to the other with sewing thread so that automatic folding and sewing of the three-ply part can be performed without causing the crosswise end of the first and the second folded parts to jut out from crosswise both ends of the towel fabric.
    Type: Grant
    Filed: December 6, 1982
    Date of Patent: October 22, 1985
    Inventor: Takanori Okada
  • Patent number: 4346099
    Abstract: The imidazole derivatives of the general formula: ##STR1## [wherein m represents an integer of 4 to 9, R.sup.1 represents a hydrogen atom or a straight- or branched-chain alkyl group containing from 1 to 12 carbon atoms, and one of R.sup.2 and R.sup.3 represents a hydrogen atom, and the other represents a halogen atom or a phenyl group, or R.sup.2 and R.sup.3 together represent --(CH.sub.2).sub.n --(in which n represents an integer of 4 to 6) or represent .dbd.CH.sub.2 ] and non-toxic salts thereof, which have a specifically inhibitory effect on the biosynthesis of thromboxane A.sub.2 (abbreviated as TXA.sub.2 hereafter) and are, therefore, useful as treating agents for diseases caused by TXA.sub.2 such as inflammation, cerebral apoplexy, myocardial infarction, acute cardiac death, cardiostenosis and thrombus etc.
    Type: Grant
    Filed: September 22, 1981
    Date of Patent: August 24, 1982
    Assignees: Ono Pharmaceutical Co., Ltd., Kissei Pharmaceutical Co., Ltd.
    Inventors: Tadao Tanouchi, Masanori Kawamura, Takanori Okada, Masaki Hayashi
  • Patent number: 4294849
    Abstract: Prostaglandin analogues of the formula:- ##STR1## (wherein R represents a hydrogen atom or a straight- or branched-chain alkyl group containing from 1 to 4 carbon atoms, the wavy line indicates attachment in .alpha.- or .beta.-configuration or a mixture thereof, and the double bonds between C.sub.2 -C.sub.3 and C.sub.13 -C.sub.14 are trans), and cyclodextrin clathrates of such acids and esters, and when R represents a hydrogen atom, non-toxic salts of such acids, possess hypotensive activity, inhibitory activity on blood platelet aggregation and vasodilator activity, and weak diarrhoea-producing activity.
    Type: Grant
    Filed: January 24, 1980
    Date of Patent: October 13, 1981
    Assignee: Warner-Lambert Company
    Inventors: Masaki Hayashi, Sadahiko Iguchi, Takanori Okada, Akiyoshi Kawasaki
  • Patent number: 4195182
    Abstract: This invention relates to prostaglandin analogues of the formula: ##STR1## (wherein R represents a hydrogen atom or a methyl group, and the double bonds between C.sub.2 -C.sub.3 and C.sub.13 -C.sub.14 are trans) and cyclodextrin clathrates of such compounds and, when R represents a hydrogen atom, non-toxic salts thereof, which possess characteristic prostaglandin-like activity.
    Type: Grant
    Filed: August 12, 1977
    Date of Patent: March 25, 1980
    Assignee: Ono Pharmaceutical Co. Ltd.
    Inventors: Masaki Hayashi, Seiji Kori, Takanori Okada
  • Patent number: 4180675
    Abstract: The present invention relates to 15-cycloalkyl-prostaglandins of the formula: ##STR1## wherein A represents a grouping of the formula: ##STR2## W represents ethylene or trans-vinylene, X represents ethylene or cis-vinylene, Y represents ethylene or trans-vinylene, R represents a hydrogen atom or a straight- or branched-chain alkyl group containing from 1 to 12 carbon atoms, R.sup.1 represents a hydrogen atom or a methyl or ethyl group, R.sup.2 represents a straight- or branched-chain alkyl group containing from 2 to 8 carbon atoms or a phenyl group unsubstituted or substituted by an alkyl group containing from 1 to 3 carbon atoms, R.sup.3 represents a hydrogen atom or a straight- or branched-chain alkyl group containing from 1 to 3 carbon atoms, and n represents 4 or 5 and cyclodextrin clathrates of such acids and esters and, when R represents a hydrogen atom, non-toxic salts thereof.These new compounds exhibit characteristic prostaglandin-like activities.
    Type: Grant
    Filed: December 5, 1977
    Date of Patent: December 25, 1979
    Assignee: Warner-Lambert Company
    Inventors: Masaki Hayashi, Seiji Kori, Isao Ohyama, Sadahiko Iguchi, Takanori Okada
  • Patent number: 4165437
    Abstract: The present invention relates to prostaglandin analogues of the general formula: ##STR1## [wherein X represents cis or trans-vinylene or ethylene, R represents ##STR2## R.sup.1 represents a hydrogen atom or a straight- or branched-chain alkyl group containing from 1 to 12 carbon atoms, R.sup.2 represents a hydrogen atom or a methyl group, R.sup.3 represents a straight- or branched-chain alkylene group containing from 1 to 7 carbon atoms and R.sup.4 represents a cycloalkyl group containing from 5 to 7 carbon atoms, a grouping of the formula: ##STR3## (wherein R.sup.5 and R.sup.6, which may be the same or different, each represent a hydrogen atom or halogen atom, a trifluoromethyl group or a straight- or branched-chain alkyl group containing from 1 to 4 carbon atoms), or a grouping of the formula: ##STR4## (wherein R.sup.5 and R.sup.6 are as hereinbefore defined), or R.sup.3 and R.sup.
    Type: Grant
    Filed: August 17, 1978
    Date of Patent: August 21, 1979
    Assignee: Ono Pharmaceutical Company, Ltd.
    Inventors: Masaki Hayashi, Seiji Kori, Yoshinobu Arai, Takanori Okada, Yoshitaka Konishi
  • Patent number: 4145555
    Abstract: The present invention relates to prostaglandin analogues of the general formula: ##STR1## ?wherein X represents cis or trans-vinylene or ethylene, Z represents ##STR2## R.sup.1 represents a hydrogen atom or a straight- or branched-chain alkyl group containing from 1 to 12 carbon atoms, R.sup.2 represents a hydrogen atom or a methyl group, R.sup.3 represents a straight- or branched-chain alkylene group containing from 1 to 7 carbon atoms and R.sup.4 represents a cycloalkyl group containing from 5 to 7 carbon atoms, a grouping of the formula: ##STR3## (wherein R.sup.5 and R.sup.6, which may be the same or different, each represent a hydrogen atom or halogen atom, a trifluoromethyl group or a straight- or branched-chain alkyl group containing from 1 to 4 carbon atoms), or a grouping of the formula: ##STR4## (wherein R.sup.5 and R.sup.6 are as hereinbefore defined), or R.sup.3 and R.sup.
    Type: Grant
    Filed: March 7, 1977
    Date of Patent: March 20, 1979
    Assignee: Ono Pharmaceutical Company
    Inventors: Masaki Hayashi, Seiji Kori, Yoshinobu Arai, Takanori Okada, Yoshitaka Konishi
  • Patent number: 4087620
    Abstract: The present invention relates to 15-cycloalkyl-prostaglandins of the formula: ##STR1## WHEREIN A represents a grouping of the formula: ##STR2## W represents ethylene or trans-vinylene, X represents ethylene or cis-vinylene, Y represents ethylene or trans-vinylene, R represents a hydrogen atom or a straight- or branched-chain alkyl group containing from 1 to 12 carbon atoms, R.sup.1 represents a hydrogen atom or a methyl or ethyl group, R.sup.2 represents a straight- or branched-chain alkyl group containing from 2 to 8 carbon atoms or a phenyl group unsubstituted or substituted by an alkyl group containing from 1 to 3 carbon atoms, R.sup.3 represents a hydrogen atom or a straight- or branched-chain alkyl group containing from 1 to 3 carbon atoms, and n represents 4 or 5) and cyclodextrin clathrates of such acids and esters and, when R represents a hydrogen atom, non-toxic salts thereof.These new compounds exhibit characteristic prostaglandin-like activities.
    Type: Grant
    Filed: July 7, 1976
    Date of Patent: May 2, 1978
    Assignee: Ono Pharmaceutical Company
    Inventors: Masaki Hayashi, Seiji Kori, Isao Ohyama, Sadahiko Iguchi, Takanori Okada
  • Patent number: 4065632
    Abstract: The present invention relates to compounds of the formula: ##STR1## wherein A represents a grouping of the formula: ##STR2## B represents an oxygen or sulphur atom, R.sup.1 and R.sup.2, which may be the same or different, each represent a hydrogen or halogen atom, a trifluoromethyl group, or a straight- or branched-chain alkyl or alkoxy group containing from 1 to 4 carbon atoms, R represents a group of the formula --COOR.sup.3, in which R.sup.3 represents a hydrogen atom or a straight- or branched-chain alkyl group containing from 1 to 12 carbon atoms, or a group of the formula --CH.sub.2 OR.sup.4, in which R.sup.4 represents a hydrogen atom or an alkylcarbonyl group containing from 2 to 5 carbon atoms and the double bonds depicted in positions C.sub.2 -C.sub.3, C.sub.5 -C.sub.6 and C.sub.13 -C.sub.14 are trans, cis and trans respectively, the cyclodextrin clathrates thereof and, when R.sup.3 in the group --COOR.sup.3 represents a hydrogen atom, non-toxic salts thereof.
    Type: Grant
    Filed: August 12, 1976
    Date of Patent: December 27, 1977
    Assignee: Ono Pharmaceutical Company
    Inventors: Masaki Hayashi, Seiji Kori, Hajimu Miyake, Takanori Okada