Patents by Inventor Takao Iida

Takao Iida has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Physiologically active substance K-252, process for producing same and pharmaceutical composition containing same
    Patent number: 4555402
    Abstract: A novel physiologically active substance K-252 having an antiallergic action is produced by culturing a microorganism of the genus Nocardiopsis.
    Type: Grant
    Filed: August 10, 1984
    Date of Patent: November 26, 1985
    Assignee: Kyowa Hakko Kogyo Co. Ltd.
    Inventors: Yuzuru Matsuda, Kazuyuki Iwahashi, Takao Iida, Noriaki Hirayama, Kozo Asano, Katsuichi Shuto, Koji Yamada, Kunikatsu Shirahata, Hiroshi Kase
  • Antibiotic substances DC-45, and their use as medicaments
    Patent number: 4511560
    Abstract: New substances designated as DC-45-A, DC-45-B.sub.1 and DC-45-B.sub.2 and represented by the following general formula: ##STR1## wherein (i) R.sub.1 and R.sub.2 together with the carbon atom therebetween represent the group ##STR2## and R.sub.3 represents ##STR3## (designated DC-45-A); (ii) R.sub.1 represents --OH, R.sub.2 represents --CH.sub.2 OH and R.sub.3 represents ##STR4## (designated DC-45-B.sub.1); or (iii) R.sub.1 and R.sub.2 together with the carbon atom therebetween represent the group ##STR5## and R.sub.3 represents ##STR6## (designated DC-45-B.sub.2). DC-45-A, DC-45-B.sub.1 and DC-45-B.sub.2 possess antibiotic and anti-tumor activity and may be obtained by culturing a microorganism of the genus Streptomyces. Preferred strain is Streptomyces bottropensis (FERM-P No. 5219; NRRL 12051).
    Type: Grant
    Filed: August 30, 1982
    Date of Patent: April 16, 1985
    Assignee: Kyowa Hakko Kogyo Kabushiki Kaisha
    Inventors: Fusao Tomita, Tatsuya Tamaoki, Kunikatsu Shirahata, Takao Iida, Makoto Morimoto, Kazuhisa Fujimoto
  • Compounds having antibiotic activity, processes for their preparation, pharmaceutical compositions containing them and their use as medicaments
    Patent number: 4459291
    Abstract: New antibacterial compounds, DC--45--A.sub.1 and DC--45--A.sub.2 are produced by fermentation of a microorganism belonging to the genus Streptomyces. The antibiotics are accumulated in the culture liquor and are isolated therefrom. These compounds are also prepared by acid hydrolysis of known compounds, DC--45--A or DC--45--B.sub.2. DC--45--A.sub.2 is also prepared by acid hydrolysis of DC--45--A.sub.1.
    Type: Grant
    Filed: July 21, 1982
    Date of Patent: July 10, 1984
    Assignee: Kyowa Hakko Kogyo Kabushiki Kaisha
    Inventors: Kunikatsu Shirahata, Takao Iida
  • Antibiotics XK-62-3 and XK-62-4 and process for production thereof
    Patent number: 4310661
    Abstract: New antibacterial compounds, XK-62-3 and XK-62-4, are produced by fermentation of microorganisms belonging to the genus Micromonospora. The compounds are accumulated in the culture liquor and are isolated therefrom.
    Type: Grant
    Filed: December 23, 1980
    Date of Patent: January 12, 1982
    Assignee: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Takao Iida, Kunikatsu Shirahata, Shinzo Ishii, Ryo Okachi, Takashi Nara
  • Antibiotics XK-62-3 and XK-62-4 and process for production thereof
    Patent number: 4298690
    Abstract: New antibacterial compounds, XK-62-3 and XK-62-4, are produced by fermentation of microorganisms belonging to the genus Micromonospora. The compounds are accumulated in the culture liquor and are isolated therefrom.
    Type: Grant
    Filed: May 16, 1978
    Date of Patent: November 3, 1981
    Assignee: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Takao Iida, Kunikatsu Shirahata, Shinzo Ishii, Ryo Okachi, Takashi Nara
  • Novel lactase
    Patent number: 4237230
    Abstract: A novel lactase having a molecular weight of about 3.times.10.sup.5, an optimum pH value of about 6.0, an optimum temperature of about 60.degree. C. and at least 1 of the ratio of the activity for hydrolyzing lactose to the activity for hydrolyzing a synthetic substrate: o-nitrophenyl-.beta.-D-galactopyranoside (Lact/ONPG ratio), which is produced by cultivating a microorganism of the genus Bacillus being capable of producing the enzyme, particularly Bacillus circulans LOB 377 (ATCC No. 31382) and isolating from the culture broth. This novel lactase is characteristic in the excellent thermostability and the high Lact/ONPG ratio and hence is useful for treating milk and milk products as well as for preventing diarrhea due to lactose intolerance, especially in babies and infants.
    Type: Grant
    Filed: June 26, 1979
    Date of Patent: December 2, 1980
    Assignee: Daiwa Kasei Kabushiki Kaisha
    Inventors: Takao Iida, Sho Ozaki, Toshihiko Kotaka
  • Fortimicin factors D and KE compounds
    Patent number: 4216308
    Abstract: New antibiotic compounds, Fortimicin factors D and KE are produced by fermentation of microorganisms belonging to the genus Micromonospora. The antibiotic compounds are accumulated in the culture liquor and are isolated therefrom. A semisynthetic method of producing Fortimicin KE utilizing Fortimicin D is also disclosed.
    Type: Grant
    Filed: December 29, 1978
    Date of Patent: August 5, 1980
    Assignee: Abbott Laboratories
    Inventors: Takao Iida, Kunikatsu Shirahata, Isao Matsubara, Masahiro Sugimoto, Shinzo Ishii, Ryo Okachi, Takashi Nara
  • Fortimicin factors KF and KG and process for production thereof
    Patent number: 4209612
    Abstract: New antibiotic compounds, Fortimicin factors KF and KG are produced by fermentation of microorganisms belonging to the genus Micromonospora. The antibiotic compounds are accumulated in the culture liquor and are isolated therefrom.
    Type: Grant
    Filed: November 6, 1978
    Date of Patent: June 24, 1980
    Assignee: Abbott Laboratories
    Inventors: Keiichi Takahashi, Takao Iida, Kunikatsu Shirahata, Masahiro Sugimoto, Shinzo Ishii, Ryo Okachi, Takashi Nara
  • Process for producing fortimicin factors
    Patent number: 4145253
    Abstract: New antibiotic compounds, Fortimicin factors D and KE are produced by fermentation of microorganisms belonging to the genus Micromonospora. The antibiotic compounds are accumulated in the culture liquor and are isolated therefrom. A semisynthetic method of producing Fortimicin KE utilizing Fortimicin D is also disclosed.
    Type: Grant
    Filed: October 27, 1977
    Date of Patent: March 20, 1979
    Assignee: Abbott Laboratories
    Inventors: Takao Iida, Kunikatsu Shirahata, Isao Maisubara, Masahiro Sugimoto, Shinzo Ishii, Ryo Okachi, Takashi Nara