Abstract: Provided is a social value evaluation device, including: a feature value generation unit configured to generate a feature value from text information on social value evaluation; an input unit configured to input text information on an evaluation target; an evaluation unit configured to evaluate a relevance between the feature value and the text information input by the input unit; and an output unit configured to output an evaluation result from the evaluation unit.

Abstract: A railroad car condition monitoring/analyzing includes: a car factor estimation unit configured to estimate car factor evaluation data from car data and evaluation data; an infrastructure factor extraction unit configured to extract infrastructure factor evaluation data from the car data, the evaluation data, and the car factor evaluation data; an infrastructure factor estimation unit configured to estimate individual infrastructure factor evaluation data from the infrastructure factor evaluation data; an infrastructure factor DB construction unit configured to store the individual infrastructure factor evaluation data in an infrastructure factor database; an infrastructure factor analysis unit configured to monitor the individual infrastructure factor evaluation data stored in the infrastructure factor database so as to analyze infrastructure factors; and a car analysis unit configured to analyze a car condition in consideration of analysis information on the infrastructure factor.

Abstract: An actinic ray-sensitive or radiation-sensitive resin composition includes a resin having a repeating unit having a group in which a phenolic hydroxyl group is protected with an acid-leaving group; a first photoacid generator that generates an acid having a pKa of ?2.00 to 2.00, in which in a case where the acid thus generated is a carboxylic acid, a pKa of the carboxylic acid is ?2.00 or more and less than 1.00; and a second photoacid generator that generates a carboxylic acid having a pKa of 1.00 or more.

Abstract: A summary generation unit includes a processor and a memory storing program instructions that cause the processor to: extract, based on components of text data regarding an Information and Communication Technology (ICT) service, one or more pieces of first feature information from the text data; a extract, based on components of a target belonging to a goal of sustainable development goals (SDGs), one or more pieces of second feature information from the target; determine a degree of similarity between the first feature information and each of the one or more pieces of second feature information; and generate a result of a cluster analysis of a set of the components that correspond to a piece of second feature information having the similarity equal to or more than a threshold among the one or more pieces of second feature information, the result of the cluster analysis being a summary of the goal.

Abstract: An environmental impact assessment device includes: an input unit configured to accept an input of a utilization purpose of an ICT service from a user, the ICT service being a target of assessment of a reduction effect for an environmental load; a first identification unit configured to refer to a storage unit in which, for each existing case about the assessment, an assessment result about the reduction effect for the environmental load for each activity item and a utilization purpose of the ICT service in the existing case are stored in association with each other, and to identify an existing case associated with the input utilization purpose; a second identification unit configured to identify an activity item for which the reduction effect is highest, for each existing case identified by the first identification unit; an acquisition unit configured to acquire a value of a parameter for an assessment expression for the environmental load, the assessment expression being previously set for each of the activ

Abstract: A value element determination device according to an embodiment includes: an input unit for inputting a function of an evaluation target service and a standpoint of a user using the evaluation target service; a first calculation unit that uses a relevance matrix having relevance between the function of the evaluation target service and each of state-changes of the user using the evaluation target service as elements to calculate the relevance between the function input via the input unit and each of the state-changes; an acquisition unit that acquires, from a database storing sets of the state-change of the user using the evaluation target service and advantage or disadvantage of the user using the evaluation target service, a set including a state-change having the relevance calculated by the first calculation unit exceeding a threshold value; a second calculation unit that calculates similarity in terms of meanings of the advantage or disadvantage included in the set acquired by the acquisition unit, the st

Abstract: Provided is an assessment device that includes: an input unit that receives, as an input, a use field of an ICT solution as an assessment target and a damage item as a target of the ICT solution; a risk extraction unit that extracts one or more risk candidates corresponding to the use field and the damage item from a database in which use fields, damage items, and risks are associated; a calculation unit that calculates cooccurrence probability between each of the one or more risk candidates and an operation target of the ICT solution; and an output unit that outputs the risk candidates based on the cooccurrence probability.

Abstract: An evaluation device includes a first calculation unit configured to calculate feature quantities of respective words, the feature quantities being regarding text data in which a target of any of goals of the SDGs is described and text data in which an outline of one or more first services a contribution of which to the goal is clear is described, the respective words being included in the text data, a generation unit configured to generate a sentence feature matrix based on the feature quantities of the respective words, a second calculation unit configured to calculate, when text data in which an outline of a second service is described is input, feature quantities of respective words, the feature quantities being regarding the text data, the respective words being included in the text data, and an evaluation unit configured to evaluate a degree of a contribution of the second service to the goal based on the feature quantities of the respective words relevant to the second service and the sentence feature

Abstract: An assessment support device capable of efficiently acquiring the elements of the value of an ICT service is provided. The assessment support device includes: a question generation unit that generates a plurality of questions including a plurality of stages of values with respect to advantages felt about an assessment target service as choices on the basis of information related to states of a user when the user uses the service and when the user does not use the service; an answer acquisition unit that acquires answers of a plurality of persons with respect to the plurality of questions generated by the question generation unit; and a statistics calculation unit that executes factor analysis with respect to the answers of the plurality of persons to extract a prescribed number of factors and calculates a value based on a distribution of values indicated by the answers to some questions having relatively higher factor loads for each of the extracted factors.

Abstract: The present inventors found that a fusion gene present in some cancer patients is an oncogene. The present invention relates to a polypeptide as a novel fusion protein, a polynucleotide encoding the polypeptide, a vector comprising the polynucleotide, a transformed cell comprising the vector, a method for detecting the fusion protein or polynucleotide, a method for screening a therapeutic agent for cancer, and a method for treating cancer that is shown to be positive for the fusion gene. Further, the present invention relates kit, primer set, and probe useful in the detection of cancer that is shown to be positive for the fusion gene.

Abstract: The present inventors found that a fusion gene present in some cancer patients is an oncogene. The present invention relates to a polypeptide as a novel fusion protein, a polynucleotide encoding the polypeptide, a vector comprising the polynucleotide, a transformed cell comprising the vector, a method for detecting the fusion protein or polynucleotide, a method for screening a therapeutic agent for cancer, and a method for treating cancer that is shown to be positive for the fusion gene.

Abstract: The present inventors found that a fusion gene present in some cancer patients is an oncogene. The present invention relates to a polypeptide as a novel fusion protein, a polynucleotide encoding the polypeptide, a vector comprising the polynucleotide, a transformed cell comprising the vector, a method for detecting the fusion protein or polynucleotide, a method for screening a therapeutic agent for cancer, and a method for treating cancer that is shown to be positive for the fusion gene.

Abstract: The present inventors found that a fusion gene present in some cancer patients is an oncogene. The present invention relates to a polypeptide as a novel fusion protein, a polynucleotide encoding the polypeptide, a vector comprising the polynucleotide, a transformed cell comprising the vector, a method for detecting the fusion protein or polynucleotide, a method for screening a therapeutic agent for cancer, and a method for treating cancer that is shown to be positive for the fusion gene. Further, the present invention relates kit, primer set, and probe useful in the detection of cancer that is shown to be positive for the fusion gene.

Abstract: As a result of studies on compounds having a selective inhibitory activity against 17?HSD type 5, the present inventors have confirmed that a {1-[(indol-2-yl)carbonyl]piperidyl}alkanol derivative has a potent selective inhibitory activity against 17?HSD type 5. The invention has been completed based on these findings. The compound of the present invention can be used as an agent for treating and/or an agent for preventing diseases associated with 17?HSD type 5, such as benign prostatic hyperplasia and prostate cancer, without accompanying adverse effects due to a decrease in testosterone.

Abstract: [Problem] An object of the present invention is to provide a novel anticancer drug which is useful for treating prostate cancer accompanying androgen receptor mutation [Means for Solution] The present inventors conducted thorough research on mutant androgen-related diseases for which the traditional anti-androgen drugs become ineffective. As a result, they found that the compound, which is an active ingredient of the pharmaceutical composition of the present invention, exhibits an inhibitory action against transcriptional activation in a human mutant androgen receptor (AR), and has an excellent antitumor action in a human prostate cancer-bearing mouse, thereby completing the present invention. Accordingly, the compound, which is an active ingredient of the pharmaceutical composition of the present invention, is useful for a series of androgen receptor-related diseases including prostate cancer.

Abstract: The present inventors found that a fusion gene present in some cancer patients is an oncogene. The present invention relates to a polypeptide as a novel fusion protein, a polynucleotide encoding the polypeptide, a vector comprising the polynucleotide, a transformed cell comprising the vector, a method for detecting the fusion protein or polynucleotide, a method for screening a therapeutic agent for cancer, and a method for treating cancer that is shown to be positive for the fusion gene. Further, the present invention relates kit, primer set, and probe useful in the detection of cancer that is shown to be positive for the fusion gene.

Abstract: The present invention provides a compound which is useful as an inhibitor against the kinase activity of EML4-ALK fusion proteins and mutant EGFR proteins. As a result of extensive and intensive studies on compounds having an inhibitory effect against the kinase activity of EML4-ALK fusion proteins and mutant EGFR proteins, the inventors of the present invention have found that the di(arylamino)aryl compound of the present invention has inhibitory activity against the kinase activity of EML4-ALK fusion proteins and mutant EGFR proteins. This finding led to the completion of the present invention.

Abstract: The present invention provides a compound which is useful as an inhibitor against the kinase activity of EML4-ALK fusion proteins and mutant EGFR proteins. As a result of extensive and intensive studies on compounds having an inhibitory effect against the kinase activity of EML4-ALK fusion proteins and mutant EGFR proteins, the inventors of the present invention have found that the di(arylamino)aryl compound of the present invention has inhibitory activity against the kinase activity of EML4-ALK fusion proteins and mutant EGFR proteins. This finding led to the completion of the present invention.

Abstract: A glass paste for a plasma display panel includes at least dielectric glass fine particles and hollow fine particles. The dielectric glass fine particle has a spherical shape or a scaly shape. Average particle diameter d1 of the dielectric glass fine particles is at most 120 nm, and a largest particle diameter thereof is at most 400 nm. Average particle diameter d2 of the hollow fine particles is at most 120 nm, and a largest particle diameter thereof is at most 400 nm.

Abstract: A plasma display panel includes a front plate and a rear plate disposed so as to face the front plate. A discharge space is formed between the front plate and the rear plate. The front plate includes display electrodes and a dielectric layer formed to coat the display electrodes. The dielectric layer includes hollow fine particles which are hollowed out inside.