Patents by Inventor Takashi Kei Kishimoto

Takashi Kei Kishimoto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PATTERNED DOSING OF IMMUNOSUPPRESSANTS COUPLED TO SYNTHETIC NANOCARRIERS
    Publication number: 20180193482
    Abstract: Provided herein are methods and related compositions for administering viral vectors and synthetic nanocarriers comprising an immunosuppressant. In some embodiments, the methods and compositions provided herein achieve improved transgene expression and/or immune response reduction, such as downregulated IgM and/or IgG immune responses.
    Type: Application
    Filed: January 5, 2018
    Publication date: July 12, 2018
    Applicant: Selecta Biosciences, Inc.
    Inventors: Petr Ilyinskii, Takashi Kei Kishimoto
  • Tolerogenic synthetic nanocarriers for generating CD8+ regulatory T cells
    Patent number: 10004802
    Abstract: Disclosed are synthetic nanocarrier methods, and related compositions, comprising administering MHC Class I-restricted and/or MHC Class II-restricted epitopes of an antigen and immunosuppressants in order to generate tolerogenic immune responses against the antigen, such as the generation of antigen-specific CD8+ regulatory T cells.
    Type: Grant
    Filed: April 27, 2012
    Date of Patent: June 26, 2018
    Assignee: Selecta Biosciences, Inc.
    Inventors: Takashi Kei Kishimoto, Christopher Fraser, Roberto A. Maldonado
  • Tolerogenic synthetic nanocarriers for antigen-specific deletion of T effector cells
    Patent number: 9987354
    Abstract: Disclosed are synthetic nanocarrier methods, and related compositions, comprising administering immunosuppressants and MHC Class I-restricted and/or MHC Class II-restricted epitopes that can generate tolerogenic immune responses (e.g., antigen-specific T effector cell deletion).
    Type: Grant
    Filed: April 27, 2012
    Date of Patent: June 5, 2018
    Assignee: Selecta Biosciences, Inc.
    Inventors: Christopher Fraser, Takashi Kei Kishimoto, Roberto A. Maldonado
  • METHODS AND COMPOSITIONS FOR TREATING CANCER
    Publication number: 20180085319
    Abstract: Provided herein are methods, and related compositions, for treating cancer. For example, a method for creating a neoplasia-neutral tolerogenic environment in a subject, such as one with cancer, and administering a recombinant immunotoxin is provided.
    Type: Application
    Filed: September 27, 2017
    Publication date: March 29, 2018
    Inventor: Takashi Kei Kishimoto
  • TOLEROGENIC SYNTHETIC NANOCARRIERS FOR ALLERGY THERAPY
    Publication number: 20160279234
    Abstract: Disclosed are synthetic nanocarrier compositions, and related methods, comprising immunosuppressants and MHC Class II-restricted epitopes of an allergen that provide tolerogenic immune responses specific to the allergen.
    Type: Application
    Filed: March 4, 2016
    Publication date: September 29, 2016
    Applicant: SELECTA BIOSCIENCES, INC.
    Inventors: TAKASHI KEI KISHIMOTO, CHRISTOPHER FRASER, ROBERTO A. MALDONADO
  • TOLEROGENIC SYNTHETIC NANOCARRIERS TO REDUCE IMMUNE RESPONSES TO THERAPEUTIC PROTEINS
    Publication number: 20160256401
    Abstract: Disclosed are synthetic nanocarrier compositions, and related methods, comprising therapeutic protein APC presentable antigens and immunosuppressants that provide tolerogenic immune responses specific to therapeutic proteins.
    Type: Application
    Filed: March 4, 2016
    Publication date: September 8, 2016
    Applicant: Selecta Biosciences, Inc.
    Inventors: Christopher Fraser, Takashi Kei Kishimoto, Roberto A. Maldonado
  • POLYSACCHARIDE COMPOSITIONS AND METHODS OF USE FOR THE TREATMENT AND PREVENTION OF DISORDERS ASSOCIATED WITH PROGENITOR CELL MOBILIZATION
    Publication number: 20160243153
    Abstract: Polysaccharide preparations lacking substantial anticoagulant activity are provided herein. Methods of making and using such preparations are provided.
    Type: Application
    Filed: May 2, 2016
    Publication date: August 25, 2016
    Inventors: Mallikarjun Sundaram, Takashi Kei Kishimoto, Sucharita Roy
  • TOLEROGENIC SYNTHETIC NANOCARRIERS TO REDUCE IMMUNE RESPONSES TO THERAPEUTIC PROTEINS
    Publication number: 20160220501
    Abstract: Disclosed are synthetic nanocarrier compositions, and related methods, comprising therapeutic protein APC presentable antigens and immunosuppressants that provide tolerogenic immune responses specific to therapeutic proteins.
    Type: Application
    Filed: February 3, 2015
    Publication date: August 4, 2016
    Inventors: Christopher Fraser, Takashi Kei Kishimoto, Roberto A. Maldonado
  • Tissue targeting
    Patent number: 9387256
    Abstract: Methods and compositions related to targeting agents to tumor tissue are described.
    Type: Grant
    Filed: April 15, 2011
    Date of Patent: July 12, 2016
    Assignee: MOMENTA PHARMACEUTICALS, INC.
    Inventors: He Zhou, Edward Cochran, Takashi Kei Kishimoto
  • Polysaccharide compositions and methods of use for the treatment and prevention of disorders associated with progenitor cell mobilization
    Patent number: 9358252
    Abstract: Polysaccharide preparations lacking substantial anticoagulant activity are provided herein. Methods of making and using such preparations are provided.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: June 7, 2016
    Assignee: MOMENTA PHARMACEUTICALS, INC.
    Inventors: Mallikarjun Sundaram, Takashi Kei Kishimoto, Sucharita Roy
  • Non-anticoagulant polysaccharide compositions
    Patent number: 9351992
    Abstract: Preparations of polysaccharides lacking substantial anticoagulant activity are provided herein. Methods of making and using such preparations are provided.
    Type: Grant
    Filed: November 3, 2008
    Date of Patent: May 31, 2016
    Assignee: MOMENTA PHARMACEUTICALS, INC.
    Inventors: Mallikarjun Sundaram, Takashi Kei Kishimoto, Sucharita Roy
  • Tolerogenic synthetic nanocarriers to reduce immune responses to therapeutic proteins
    Patent number: 9295718
    Abstract: Disclosed are synthetic nanocarrier compositions, and related methods, comprising therapeutic protein APC presentable antigens and immunosuppressants that provide tolerogenic immune responses specific to therapeutic proteins.
    Type: Grant
    Filed: April 27, 2012
    Date of Patent: March 29, 2016
    Assignee: Selecta Biosciences, Inc.
    Inventors: Christopher Fraser, Takashi Kei Kishimoto, Roberto A. Maldonado
  • Tolerogenic synthetic nanocarriers for allergy therapy
    Patent number: 9289476
    Abstract: Disclosed are synthetic nanocarrier compositions, and related methods, comprising immunosuppressants and MHC Class II-restricted epitopes of an allergen that provide tolerogenic immune responses specific to the allergen.
    Type: Grant
    Filed: April 27, 2012
    Date of Patent: March 22, 2016
    Assignee: Selecta Biosciences, Inc.
    Inventors: Takashi Kei Kishimoto, Christopher Fraser, Roberto A. Maldonado
  • Tolerogenic synthetic nanocarriers to reduce cytotoxic T lymphocyte responses
    Patent number: 9289477
    Abstract: Disclosed are synthetic nanocarrier compositions, and related methods, comprising MHC Class I-restricted and/or MHC Class II-restricted epitopes associated with undesired CD8+ T cell responses and immunosuppressants that provide tolerogenic immune responses against antigens that comprise the epitopes.
    Type: Grant
    Filed: April 27, 2012
    Date of Patent: March 22, 2016
    Assignee: Selecta Biosciences, Inc.
    Inventors: Christopher Fraser, Takashi Kei Kishimoto, Roberto A. Maldonado
  • METHODS AND COMPOSITIONS FOR ATTENUATING GENE EXPRESSION MODULATING ANTI-VIRAL TRANSFER VECTOR IMMUNE RESPONSES
    Publication number: 20160074427
    Abstract: Provided herein are methods and related compositions for administering viral transfer vectors and antigen-presenting cell targeted immunosuppressants.
    Type: Application
    Filed: September 7, 2015
    Publication date: March 17, 2016
    Applicant: Selecta Biosciences, Inc.
    Inventor: Takashi Kei Kishimoto
  • METHODS AND COMPOSITIONS FOR ATTENUATING GENE THERAPY ANTI-VIRAL TRANSFER VECTOR IMMUNE RESPONSES
    Publication number: 20160074531
    Abstract: Provided herein are methods and related compositions for administering viral transfer vectors and antigen-presenting cell targeted immunosuppressants.
    Type: Application
    Filed: September 7, 2015
    Publication date: March 17, 2016
    Applicant: Selecta Biosciences, Inc.
    Inventor: Takashi Kei Kishimoto
  • METHODS AND COMPOSITIONS FOR ATTENUATING EXON SKIPPING ANTI-VIRAL TRANSFER VECTOR IMMUNE RESPONSES
    Publication number: 20160074372
    Abstract: Provided herein are methods and related compositions for administering viral transfer vectors and antigen-presenting cell targeted immunosuppressants.
    Type: Application
    Filed: September 7, 2015
    Publication date: March 17, 2016
    Applicant: Selecta Biosciences, Inc.
    Inventor: Takashi Kei Kishimoto
  • METHODS AND COMPOSITIONS FOR ATTENUATING GENE EDITING ANTI-VIRAL TRANSFER VECTOR IMMUNE RESPONSES
    Publication number: 20160074532
    Abstract: Provided herein are methods and related compositions for administering viral transfer vectors and antigen-presenting cell targeted immunosuppressants.
    Type: Application
    Filed: September 7, 2015
    Publication date: March 17, 2016
    Applicant: Selecta Biosciences, Inc.
    Inventor: Takashi Kei Kishimoto
  • METHODS AND COMPOSITIONS FOR ATTENUATING ANTI-VIRAL TRANSFER VECTOR IMMUNE RESPONSES
    Publication number: 20160067228
    Abstract: Provided herein are methods and related compositions for administering viral transfer vectors and antigen-presenting cell targeted immunosuppressants.
    Type: Application
    Filed: September 7, 2015
    Publication date: March 10, 2016
    Applicant: Selecta Biosciences, Inc.
    Inventor: Takashi Kei Kishimoto
  • POLYSACCHARIDE COMPOSITIONS AND METHODS OF USE FOR THE TREATMENT AND PREVENTION OF DISORDERS ASSOCIATED WITH PROGENITOR CELL MOBILIZATION
    Publication number: 20160060366
    Abstract: Polysaccharide preparations lacking substantial anticoagulant activity are provided herein. Methods of making and using such preparations are provided.
    Type: Application
    Filed: November 9, 2015
    Publication date: March 3, 2016
    Inventors: Mallikarjun Sundaram, Takashi Kei Kishimoto, Sucharita Roy