Patents by Inventor Takashi Kei Kishimoto

Takashi Kei Kishimoto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TOLEROGENIC SYNTHETIC NANOCARRIERS FOR ALLERGY THERAPY
    Publication number: 20160030554
    Abstract: Disclosed are synthetic nanocarrier compositions, and related methods, comprising immunosuppressants and MHC Class II-restricted epitopes of an allergen that provide tolerogenic immune responses specific to the allergen.
    Type: Application
    Filed: July 27, 2015
    Publication date: February 4, 2016
    Applicant: Selecta Biosciences, Inc.
    Inventors: Takashi Kei Kishimoto, Christopher Fraser, Roberto A. Maldonado
  • TOLEROGENIC SYNTHETIC NANOCARRIERS FOR GENERATING CD8+ REGULATORY T CELLS
    Publication number: 20160030555
    Abstract: Disclosed are synthetic nanocarrier methods, and related compositions, comprising administering MHC Class I-restricted and/or MHC Class II-restricted epitopes of an antigen and immunosuppressants in order to generate tolerogenic immune responses against the antigen, such as the generation of antigen-specific CD8+ regulatory T cells.
    Type: Application
    Filed: July 27, 2015
    Publication date: February 4, 2016
    Applicant: Selecta Biosciences, Inc.
    Inventors: Takashi Kei Kishimoto, Christopher Fraser, Roberto A. Maldonado
  • TOLEROGENIC SYNTHETIC NANOCARRIERS TO REDUCE CYTOTOXIC T LYMPHOCYTE RESPONSES
    Publication number: 20160022650
    Abstract: Disclosed are synthetic nanocarrier compositions, and related methods, comprising MHC Class I-restricted and/or MHC Class II-restricted epitopes associated with undesired CD8+ T cell responses and immunosuppressants that provide tolerogenic immune responses against antigens that comprise the epitopes.
    Type: Application
    Filed: July 27, 2015
    Publication date: January 28, 2016
    Applicant: Selecta Biosciences, Inc.
    Inventors: Christopher Fraser, Takashi Kei Kishimoto, Roberto A. Maldonado
  • METHODS AND COMPOSITIONS FOR TREATMENT WITH SYNTHETIC NANOCARRIERS AND IMMUNE CHECKPOINT INHIBITORS
    Publication number: 20150374815
    Abstract: Disclosed are synthetic nanocarrier compositions and immune checkpoint inhibitor compositions and related methods for administration to a subject.
    Type: Application
    Filed: June 25, 2015
    Publication date: December 31, 2015
    Applicant: Selecta Biosciences, Inc.
    Inventors: Takashi Kei Kishimoto, Petr IIyinskii
  • TOLEROGENIC SYNTHETIC NANOCARRIERS FOR T-CELL-MEDIATED AUTOIMMUNE DISEASE
    Publication number: 20150359865
    Abstract: Disclosed are synthetic nanocarrier compositions, and related methods, comprising autoimmune antigens and immunosuppressants to reduce immune responses to autoimmune antigens.
    Type: Application
    Filed: June 17, 2015
    Publication date: December 17, 2015
    Inventor: Takashi Kei Kishimoto
  • Polysaccharide compositions and methods of use for the treatment and prevention of disorders associated with progenitor cell mobilization
    Patent number: 9212233
    Abstract: Polysaccharide preparations lacking substantial anticoagulant activity are provided herein. Methods of making and using such preparations are provided.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: December 15, 2015
    Assignee: MOMENTA PHARMACEUTICALS, INC.
    Inventors: Mallikarjun Sundaram, Takashi Kei Kishimoto, Sucharita Roy
  • TOLEROGENIC SYNTHETIC NANOCARRIERS TO REDUCE IMMUNE RESPONSES TO THERAPEUTIC PROTEINS
    Publication number: 20150335762
    Abstract: Disclosed are synthetic nanocarrier compositions, and related methods, comprising therapeutic protein APC presentable antigens and immunosuppressants that provide tolerogenic immune responses specific to therapeutic proteins.
    Type: Application
    Filed: July 27, 2015
    Publication date: November 26, 2015
    Applicant: Selecta Biosciences, Inc.
    Inventors: Christopher Fraser, Takashi Kei Kishimoto, Roberto A. Maldonado
  • TOLEROGENIC SYNTHETIC NANOCARRIERS TO REDUCE ANTIBODY RESPONSES
    Publication number: 20150320728
    Abstract: Disclosed are synthetic nanocarrier compositions, and related methods, comprising MHC Class II-restricted epitopes and immunosuppressants that provide tolerogenic immune responses, such as a reduction in CD4+T cell help specific to an antigen.
    Type: Application
    Filed: July 27, 2015
    Publication date: November 12, 2015
    Applicant: Selecta Biosciences, Inc.
    Inventors: Christopher Fraser, Takashi Kei Kishimoto, Roberto A. Maldonado
  • TOLEROGENIC SYNTHETIC NANOCARRIERS FOR ANTIGEN-SPECIFIC DELETION OF T EFFECTOR CELLS
    Publication number: 20150320884
    Abstract: Disclosed are synthetic nanocarrier methods, and related compositions, comprising administering immunosuppressants and MHC Class I-restricted and/or MHC Class II-restricted epitopes that can generate tolerogenic immune responses (e.g., antigen-specific T effector cell deletion).
    Type: Application
    Filed: July 27, 2015
    Publication date: November 12, 2015
    Applicant: Selecta Biosciences, Inc.
    Inventors: Christopher Fraser, Takashi Kei Kishimoto, Roberto A. Maldonado
  • Saccharide structures and methods of making and using such structures
    Patent number: 9163047
    Abstract: Described are oligosaccharides having a protecting group at two, a plurality, a majority of, or each position in the oligosaccharide which is amenable to derivatization. Collections, libraries and methods of making and using such oligosaccharides are also described.
    Type: Grant
    Filed: November 8, 2013
    Date of Patent: October 20, 2015
    Assignee: MOMENTA PHARMACEUTICALS, INC.
    Inventors: Sucharita Roy, Takashi Kei Kishimoto, Ganesh Kaundinya
  • REPEATED ADMINISTRATION OF NON-IMMUNOSUPPRESSIVE ANTIGEN SPECIFIC IMMUNOTHERAPEUTICS
    Publication number: 20140356361
    Abstract: This invention relates to repeated administration of antigen-specific immunotherapeutics using protocols, or elements thereof, that do not induce immunosuppression. In some embodiments, the protocol has been previously shown not to induce immunosuppression in a subject.
    Type: Application
    Filed: June 4, 2014
    Publication date: December 4, 2014
    Applicant: Selecta Biosciences, Inc.
    Inventors: Roberto A. Maldonado, Takashi Kei Kishimoto
  • METHODS AND COMPOSITIONS FOR ENHANCING CD4+ REGULATORY T CELLS
    Publication number: 20140335186
    Abstract: Disclosed are methods and related compositions for administering immunosuppressants and therapeutic macromolecules for enhancing CD4+ regulatory T cells.
    Type: Application
    Filed: May 2, 2014
    Publication date: November 13, 2014
    Applicant: Selecta Biosciences, Inc.
    Inventors: Takashi Kei Kishimoto, Roberto A. Maldonado
  • DOSING COMBINATIONS FOR REDUCING UNDESIRED HUMORAL IMMUNE RESPONSES
    Publication number: 20140328923
    Abstract: Disclosed are dosings of therapeutic macromolecules and immunosuppressants, in some embodiments attached to synthetic nanocarriers, in combination with dosings of therapeutic macromolecules without synthetic nanocarriers, and related methods that provide reduced humoral immune responses.
    Type: Application
    Filed: May 2, 2014
    Publication date: November 6, 2014
    Applicant: Selecta Biosciences, Inc.
    Inventors: Roberto A. Maldonado, Takashi Kei Kishimoto
  • DELIVERY OF IMMUNOSUPPRESSANTS HAVING A SPECIFIED PHARMACODYNAMIC EFFECTIVE-LIFE AND ANTIGEN FOR THE INDUCTION OF IMMUNE TOLERANCE
    Publication number: 20140328924
    Abstract: This invention relates to methods that provide immunosuppressants and therapeutic macromolecules that are administered within a pharmacodynamically effective window of the immunosuppressants to induce immune tolerance to the therapeutic macromolecules. The methods allow shifting the immune response in favor of tolerogenic immune response development specific to the therapeutic macromolecule.
    Type: Application
    Filed: May 2, 2014
    Publication date: November 6, 2014
    Applicant: Selecta Biosciences, Inc.
    Inventor: Takashi Kei Kishimoto
  • TOLEROGENIC SYNTHETIC NANOCARRIERS AND THERAPEUTIC MACROMOLECULES FOR REDUCED OR ENHANCED PHARMACODYNAMIC EFFECTS
    Publication number: 20140328854
    Abstract: Disclosed are compositions and methods that provide pharmacodynamic effects specific to therapeutic macromolecules. The effects may result from reduced doses of therapeutic macromolecules in combination with immunosuppressant doses. The effects may also be enhanced with such compositions.
    Type: Application
    Filed: May 2, 2014
    Publication date: November 6, 2014
    Applicant: Selecta Biosciences, Inc.
    Inventors: Roberto A. Maldonado, Takashi Kei Kishimoto
  • Copolymer assay
    Patent number: 8753833
    Abstract: The present invention provides methods and compositions for evaluating one or more properties of an amino acid copolymer.
    Type: Grant
    Filed: June 19, 2008
    Date of Patent: June 17, 2014
    Assignee: Momenta Pharmaceuticals, Inc.
    Inventors: Josephine S. D'Alessandro, Takashi Kei Kishimoto, Aileen Healy
  • POLYSACCHARIDE COMPOSITIONS AND METHODS OF USE FOR THE TREATMENT AND PREVENTION OF DISORDERS ASSOCIATED WITH PROGENITOR CELL MOBILIZATION
    Publication number: 20140031315
    Abstract: Polysaccharide preparations lacking substantial anticoagulant activity are provided herein. Methods of making and using such preparations are provided.
    Type: Application
    Filed: September 27, 2013
    Publication date: January 30, 2014
    Applicant: MOMENTA PHARMACEUTICALS, INC.
    Inventors: Mallikarjun Sundaram, Takashi Kei Kishimoto, Sucharita Roy
  • POLYSACCHARIDE COMPOSITIONS AND METHODS OF USE FOR THE TREATMENT AND PREVENTION OF DISORDERS ASSOCIATED WITH PROGENITOR CELL MOBILIZATION
    Publication number: 20140024602
    Abstract: Polysaccharide preparations lacking substantial anticoagulant activity are provided herein. Methods of making and using such preparations are provided.
    Type: Application
    Filed: September 27, 2013
    Publication date: January 23, 2014
    Applicant: MOMENTA PHARMACEUTICALS, INC.
    Inventors: Mallikarjun Sundaram, Takashi Kei Kishimoto, Sucharita Roy
  • Saccharide structures and methods of making and using such structures
    Patent number: 8614314
    Abstract: Described are oligosaccharides having a protecting group at two, a plurality, a majority of, or each position in the oligosaccharide which is amenable to derivatization. Collections, libraries and methods of making and using such oligosaccharides are also described.
    Type: Grant
    Filed: May 29, 2009
    Date of Patent: December 24, 2013
    Assignee: Momenta Pharmaceuticals, Inc.
    Inventors: Roy Sucharita, Takashi Kei Kishimoto, Ganesh Venkataraman
  • Polysaccharide compositions and methods of use for the treatment and prevention of disorders associated with progenitor cell mobilization
    Patent number: 8592393
    Abstract: Polysaccharide preparations lacking substantial anticoagulant activity are provided herein. Methods of making and using such preparations are provided.
    Type: Grant
    Filed: April 16, 2010
    Date of Patent: November 26, 2013
    Assignee: Momenta Pharmaceuticals, Inc.
    Inventors: Mallikarjun Sundaram, Takashi Kei Kishimoto, Sucharita Roy