Patents by Inventor Takashi Miwa

Takashi Miwa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220380879
    Abstract: A zinc spraying material comprises a zinc material containing zinc; and a sulfate salt whose solubility in water is 1/8 or more of the solubility of calcium sulfate. The content of the sulfate salt in the zinc spraying material can be 0.006 to 0.14 mol based on 100 g of the content of the zinc material. Note that the sulfate salt can be at least one of potassium sulfate, sodium sulfate, magnesium sulfate, calcium sulfate, ferric sulfate, ferrous sulfate, lithium sulfate, calcium sulfate, and aluminum sulfate. Also, the zinc material is zinc. Alternatively, the zinc material can also be a zinc alloy containing zinc as the main component and at least one metal selected from aluminum and magnesium.
    Type: Application
    Filed: November 6, 2019
    Publication date: December 1, 2022
    Inventors: Takashi Miwa, Azusa Ishii, Masamitsu Watanabe, Soichi Oka
  • Patent number: 11506649
    Abstract: To estimate penetration behavior of hydrogen up until hydrogen content reaches saturation even if load stress on steel is equal to or higher than threshold stress.
    Type: Grant
    Filed: April 24, 2019
    Date of Patent: November 22, 2022
    Assignee: NIPPON TELEGRAPH AND TELEPHONE CORPORATION
    Inventors: Takuya Kamisho, Masamitsu Watanabe, Takashi Miwa, Yosuke Takeuchi
  • Patent number: 11434279
    Abstract: This invention relates to selective inhibition of the alternative pathway (AP) of the complement system using an anti-factor D antibody. Specifically, the invention relates to methods of treating an AP-mediated disease or AP-mediated disorder in an individual by contacting the individual with an anti-factor D antibody.
    Type: Grant
    Filed: February 9, 2018
    Date of Patent: September 6, 2022
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Wenchao Song, Lin Zhou, Sayaka Sato, Takashi Miwa, Damodar Gullipalli, Madhu Golla
  • Publication number: 20220266171
    Abstract: A first chromatogram is obtained by analyzing a second standard sample by size exclusion chromatography analysis using a first detector. Also, a second chromatogram is obtained by analyzing a solvent for the second standard sample by size exclusion chromatography analysis using the first detector. Then, from the difference between the first chromatogram and the second chromatogram, a third elution time in size exclusion chromatography analysis of the second standard sample using the first detector is determined.
    Type: Application
    Filed: June 24, 2019
    Publication date: August 25, 2022
    Inventors: Azusa Ishii, Takashi Miwa, Masamitsu Watanabe, Soichi Oka
  • Patent number: 11391665
    Abstract: A painting fiber probe having a measurement surface on which a coating film is formed with the same painting specification as that of a sample (painted steel sheet) is placed in a test tank together with the sample. A cycle consisting of three steps of saline water spraying, drying and wetting is repeated on the sample and the painting fiber probe. In the drying step of the cycle, absorbance at a specific wavelength of the coating film formed on the painting fiber probe is measured at a regular interval and drying is ended when the measured absorbance satisfies a predetermined condition.
    Type: Grant
    Filed: April 5, 2019
    Date of Patent: July 19, 2022
    Assignee: NIPPON TELEGRAPH AND TELEPHONE CORPORATION
    Inventors: Takashi Miwa, Azusa Ishii
  • Publication number: 20220204602
    Abstract: This invention relates to inhibition of the complement signaling using an anti-C5 antibody or fusion protein thereof. Specifically, the invention relates to methods of treating a complement-mediated disease or complement-mediated disorder in an individual by contacting the individual with an anti-C5 antibody fusion protein thereof.
    Type: Application
    Filed: April 24, 2020
    Publication date: June 30, 2022
    Inventors: Wenchao Song, Takashi Miwa, Damodar Gullipalli, Sayaka Sato, Ping Tsui, Yingjie Zhu, Xihua Zhu
  • Publication number: 20220177556
    Abstract: This invention relates to inhibition of the complement signaling using an anti-C5 antibody. Specifically, the invention relates to methods of treating a complement-mediated disease or complement-mediated disorder in an individual by contacting the individual with an anti-C5 antibody.
    Type: Application
    Filed: September 6, 2019
    Publication date: June 9, 2022
    Inventors: Wenchao Song, Takashi Miwa, Damodar Gullipalli, Ping Tsui, Sayaka Sato
  • Publication number: 20220153824
    Abstract: This invention relates to inhibition of the complement signaling using an anti-C5a antibody. Specifically, the invention relates to methods of treating a complement-mediated disease or complement-mediated disorder in an individual by contacting the individual with an anti-C5a antibody.
    Type: Application
    Filed: February 2, 2022
    Publication date: May 19, 2022
    Inventors: Wenchao Song, Sayaka Sato, Takashi Miwa, Damodar Gullipalli
  • Patent number: 11274146
    Abstract: This invention relates to inhibition of the complement signaling using an anti-C5a antibody. Specifically, the invention relates to methods of treating a complement-mediated disease or complement-mediated disorder in an individual by contacting the individual with an anti-C5a antibody.
    Type: Grant
    Filed: March 23, 2018
    Date of Patent: March 15, 2022
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Wenchao Song, Sayaka Sato, Takashi Miwa, Damodar Gullipalli
  • Publication number: 20220034828
    Abstract: In a first step, a sample formed of a polyester or decomposition products of a polyester is dissolved in a pretreatment liquid containing a secondary amine to obtain a reaction product (amide) of the sample. In a second step, the obtained reaction product, amide, is mixed into a solvent containing deuterated chloroform and deuterated 1,1,1,3,3,3-hexafluoro-2-propanol to fabricate a sample liquid. In a third step, the amount of the amide in the sample liquid is measured through a nuclear magnetic resonance spectroscopy aiming at hydrogen atoms to determine the amount of acid anhydride in the sample.
    Type: Application
    Filed: December 13, 2019
    Publication date: February 3, 2022
    Inventors: Azusa Ishii, Takashi Miwa, Masamitsu Watanabe, Soichi Oka
  • Publication number: 20220003699
    Abstract: In a first step, a sample formed of a polyester or decomposition products of a polyester is dissolved in a pretreatment liquid containing 1,1,1,3,3,3-hexafluoro-2-propanol and an organic base to produce a reaction product of the sample, and in a second step, the obtained reaction product is mixed into a solvent (measurement solvent) containing deuterated chloroform and deuterated 1,1,1,3,3,3-hexafluoro-2-propanol to fabricate a sample liquid. Next, in a third step, the amount of the reaction product in the sample liquid is measured through NMR aiming at hydrogen atoms to determine the amount of an acid anhydride structure in the sample.
    Type: Application
    Filed: December 13, 2019
    Publication date: January 6, 2022
    Inventors: Azusa Ishii, Takashi Miwa, Masamitsu Watanabe, Soichi Oka
  • Publication number: 20210318228
    Abstract: An accelerated corrosion test apparatus that accelerates corrosion of reinforcing steel contained in reinforced concrete specimen having cracking includes: a moisture sensor disposed near the reinforcing steel exposed from a cracked portion of concrete; a weight measuring instrument that measures a weight of the reinforced concrete specimen; and a control terminal that is connected both to the moisture sensor and to the weight measuring instrument and controls a temperature and humidity control device, thereby alternately and repeatedly performing a wetting step of supplying moisture to the inside of a crack in the cracked concrete, and a drying step of removing moisture in the inside of the crack and moisture on the exposed surface of the reinforcing steel, wherein the control terminal terminates the wetting step and starts the drying step when moisture is detected in the moisture sensor, or when change in slope of weight change of the reinforced concrete specimen is detected, after the start of the wetting
    Type: Application
    Filed: June 28, 2019
    Publication date: October 14, 2021
    Inventors: Yosuke Takeuchi, Takashi Miwa, Takuya Kamisho, Soichi Oka
  • Publication number: 20210285082
    Abstract: The galvanized member includes a member formed of a metal and a hot-dip galvanized layer formed on the surface of the member. The hot-dip galvanized layer contains a sulfate salt having a higher water solubility than calcium sulfate. A sulfate salt content of the hot-dip galvanized layer is preferably 0.008 to 0.133 mol based on 100 g of zinc. The sulfate salt contained in the hot-dip galvanized layer is preferably at least one of potassium sulfate, sodium sulfate, magnesium sulfate, calcium sulfate, ferric sulfate, ferrous sulfate, lithium sulfate, calcium sulfate, and aluminum sulfate.
    Type: Application
    Filed: June 28, 2019
    Publication date: September 16, 2021
    Inventors: Takashi Miwa, Azusa Ishii
  • Publication number: 20210239674
    Abstract: To estimate penetration behavior of hydrogen up until hydrogen content reaches saturation even if load stress on steel is equal to or higher than threshold stress.
    Type: Application
    Filed: April 24, 2019
    Publication date: August 5, 2021
    Inventors: Takuya Kamisho, Masamitsu Watanabe, Takashi Miwa, Yosuke Takeuchi
  • Publication number: 20210181131
    Abstract: In a first step, a sample liquid is fabricated by mixing a sample formed of a polyester or decomposition products of a polyester into a solvent. The solvent used here contains chloroform and 2,2,2-trifluoroethanol and has an organic base added thereto. The organic base is at least one of a primary amine, a secondary amine, a tertiary amine and a heterocyclic amine.
    Type: Application
    Filed: May 10, 2019
    Publication date: June 17, 2021
    Inventors: Azusa Ishii, Takashi Miwa
  • Publication number: 20210181129
    Abstract: In a first step, a sample liquid is fabricated by mixing a sample formed of a polyester or decomposition products of a polyester into a solvent. The solvent used here contains chloroform and 2,2,2-trifluoroethanol and has an organic base added thereto. The organic base is at least one of a primary amine, a secondary amine, a tertiary amine and a heterocyclic amine. Next, in a second step, each of the amount of the terephthalic acid terminal and the amount of the hydroxy group terminal in the sample liquid is measured through a nuclear magnetic resonance spectroscopy aiming at hydrogen atoms. Subsequently, in a third step, the number average molecular weight of the sample is calculated from the amount of the terephthalic acid terminal and the amount of the hydroxy group terminal measured in the second step.
    Type: Application
    Filed: May 10, 2019
    Publication date: June 17, 2021
    Inventors: Azusa Ishii, Takashi Miwa
  • Publication number: 20210171592
    Abstract: A recombinant vector having an expression cassette comprising a modified human factor H (hfH) gene is provided, wherein said hfH gene encodes a hfH protein variant comprising SCR1-4, 19-20, and one or more of SCR7, SCR17 and/or SCR18. Also provided are pharmaceutical compositions containing this vector and uses therefor in treating AMD and/or other complement associated diseases.
    Type: Application
    Filed: January 22, 2021
    Publication date: June 10, 2021
    Inventors: Wenchao Song, Damodar Gullipalli, Takashi Miwa
  • Publication number: 20210155808
    Abstract: A coating material is allowed to contain a sulfate having a higher degree of solubility in water than that of calcium sulfate. The sulfate is an additive for coating materials which is used for reducing the consumption of zinc (including zinc oxide) in a coating film formed from the coating material and the corrosion of a base material when the coating film is scratched. The content of the sulfate can be 0.004 to 0.65 mol per 100 g of the content of zinc. Alternatively, the content of the sulfate may be 0.006 to 0.186 mol per 100 g of a heating residue (except for the sulfate added) of a coating film.
    Type: Application
    Filed: May 27, 2019
    Publication date: May 27, 2021
    Inventors: Takashi Miwa, Masamitsu Watanabe, Azusa Ishii, Soichi Oka
  • Patent number: 10988519
    Abstract: Provided herein is a recombinant viral vector having packaged therein an expression cassette comprising an engineered complement regulator factor H (fH), wherein the gene encodes a hfH protein variant comprising short consensus repeats (SCRs) 1-4, 6-8, and 17-20. Pharmaceutical compositions containing this vector and plasmids comprising nucleic acid sequences that encode the fH protein variant are also provided.
    Type: Grant
    Filed: September 23, 2016
    Date of Patent: April 27, 2021
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Wenchao Song, Damodar Gullipalli, Takashi Miwa
  • Publication number: 20210116357
    Abstract: A painting fiber probe having a measurement surface on which a coating film is formed with the same painting specification as that of a sample (painted steel sheet) is placed in a test tank together with the sample. A cycle consisting of three steps of saline water spraying, drying and wetting is repeated on the sample and the painting fiber probe. In the drying step of the cycle, absorbance at a specific wavelength of the coating film formed on the painting fiber probe is measured at a regular interval and drying is ended when the measured absorbance satisfies a predetermined condition.
    Type: Application
    Filed: April 5, 2019
    Publication date: April 22, 2021
    Inventors: Takashi Miwa, Azusa Ishii