Patents by Inventor Takashi Okamura
Takashi Okamura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 6288070Abstract: Disclosed is a triazolopurine derivative represented by the general formula: wherein R1 and R2 represent the same groups as those described in the specification; and A represents a group: wherein R3 represents the same groups as those described in the specification. This compound is incorporated in a pharmaceutical composition because of its affinity to an adenosine A3 receptor, and is used as an adenosine A3 receptor antagonist or a remedy for asthma.Type: GrantFiled: October 3, 2000Date of Patent: September 11, 2001Assignee: Otsuka Pharmaceutical Factory, Inc.Inventors: Takashi Okamura, Yasuhisa Kurogi, Hiroshi Nishikawa
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Patent number: 6276287Abstract: An iron compound catalyst for inhibiting the generation of dioxin of the present invention, comprise iron oxide particles, iron oxide hydroxide particles or mixed particles thereof having a catalytic activity capable of converting not less than 15 % of carbon monoxide into carbon dioxide when 2.8×10−4 mol of iron oxide particles obtained by heat-treating said iron compound catalyst in air at a temperature of 800° C. for 15 minutes, are instantaneously contacted with 6.1×107 mol of carbon monoxide at a temperature of 250° C. at a space velocity (SV) of 42,400 h−1 in an inert gas atmosphere using a pulse catalytic reactor, the iron oxide particles or said iron oxide hydroxide particles having an average particle size of 0.01 to 2.0 &mgr;m, a BET specific surface area of 0.2 to 200 m2/g, a phosphorus content of not more than 0.02 % by weight, a sulfur content of not more than 0.6 % by weight and a sodium content of not more than 0.5 % by weight.Type: GrantFiled: May 3, 1999Date of Patent: August 21, 2001Assignees: Toda Kogyo Corporation, Naikai Plant Kabushiki KaishaInventors: Tomoyuki Imai, Toshiki Matsui, Yasuhiko Fujii, Satoshi Hatakeyama, Kojiro Tsutsumi, Tomoko Okita, Hiroshi Inoue, Tatsuaki Baba, Masaki Ishihara, Takashi Okamura
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Patent number: 6245779Abstract: The present invention provides a naphthyridine derivative represented by the formula (1) wherein A is lower alkylene; R1 is H or an electron pair “-”; R2 is optionally substituted phenyl; when R1 is an electron pair “-”, R3 is a group represented by (wherein R4 and R5 each represent lower alkyl, etc.); when R1 is H, R3 is a group —S—R6 (wherein R6 is lower alkyl, etc.); and R7 is H or lower alkyl; and also provides an analgesic composition containing the above derivative as an active ingredient.Type: GrantFiled: December 9, 1999Date of Patent: June 12, 2001Assignee: Otsuka Pharmaceutical Factory, Inc.Inventors: Tadao Shibutani, Yasuo Shoji, Takashi Okamura, Tsuneo Yasuda, Takeshi Iwamoto
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Patent number: 6166016Abstract: The invention provides amide derivatives which are useful as analgesics, anti-inflammatory agents, antimicrobial drugs, hypoglycemic agents, hypolipidemic agents, antihypertensive agents, anti-cancer agents, etc., the derivatives being represented by the formula ##STR1## wherein ring A represents a benzene ring, a naphthalene ring, a pyridine ring or a furan ring; R.sup.4 represents a heterocyclic group selected from the group consisting of a lower alkyl-substituted thieno[3,2-d]pyrimidin-4-yl group, an optionally substituted pyrazolo[1,5-a]-1,3,5-triazin-4-yl group, a pyrazolo[3,4-d]pyrimidin-4-yl group substituted at the 6-position and a purin-6-yl group substituted at the 2-position; and R.sup.Type: GrantFiled: December 2, 1998Date of Patent: December 26, 2000Assignee: Otsuka Pharmaceutical Factory, Inc.Inventors: Takashi Okamura, Yasuo Shoji, Tadao Shibutani, Tsuneo Yasuda, Takeshi Iwamoto
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Patent number: 6110240Abstract: The present invention provides a method of manufacturing a superhard article with diamond coat having an excellent resistance against breakaway or peeling off of its coat, in particular, a cutting tool. A carbide base material formed to a desired shape containing tungsten carbide (WC) as a main component is soaked in a solution of alkali chloride and undergoes electrolytic etching on the surface of the base material at a maximum removal speed of 0.2 to 1.5 .mu.m/min for 3 to 30 minutes and, after the surface of the base material is washed, a diamond coat is developed on the surface of the base material by vapor deposition.Type: GrantFiled: November 25, 1997Date of Patent: August 29, 2000Assignee: NGK Spark Plug Co., Ltd.Inventors: Hiromi Saguchi, Takashi Okamura, Satoshi Iio
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Patent number: 5985882Abstract: The invention provides pyrazolo[1,5-a]pyrimidine derivatives which are useful as potent analgesics and represented by the formula ##STR1## wherein R.sup.1 is lower alkenyl, hydroxy(lower)alkyl, (lower)alkylthio(lower)alkyl, (lower)alkanoyloxy(lower)alkyl, (lower)alkoxy(lower)alkyl, furyl or thienyl, R.sup.2 is pyridyl, 1-oxide-pyridyl, lower alkyl-substituted pyrazinyl, lower alkyl-substituted pyrimidinyl, or phenyl which may have 1 to 3 substituents selected from the group consisting of lower alkyl, lower alkoxy and halogen, R.sup.3 is hydrogen or halogen, and A is a single bond or lower alkylene.Type: GrantFiled: October 10, 1997Date of Patent: November 16, 1999Assignee: Otsuka Pharmaceutical Factory, Inc.Inventors: Makoto Inoue, Takashi Okamura, Yasuo Shoji, Kinji Hashimoto, Masayuki Ohara, Tsuneo Yasuda
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Patent number: 5955155Abstract: A CVD method of forming a diamond coated article is disclosed, which consists essentially of a substrate and a plurality of polycrystalline diamond film layers accumulatively coated thereon in a total thickness of at least 20 .mu.m, wherein each of the polycrystalline diamond film layers (i) has a thickness of 6 to 13 .mu.m, (ii) has an average crystallite size in the surface direction thereof of 3 to 7 .mu.m, (iii) has (111) oriented diamond crystallites exposed on the surface thereof, and (iv) satisfies the relationship: I(N)/I(D)<0.2, wherein I(D) represents an intensity of diamond Raman peak in counts/sec appearing around 1333 cm.sup.-1 and I(N) represents a maximum intensity among non-diamond Raman peaks appearing between 1200 cm.sup.-1 and 1600 cm.sup.-1.Type: GrantFiled: October 8, 1998Date of Patent: September 21, 1999Assignee: NGK Spark Plug Co., Ltd.Inventors: Hiroshi Yamamoto, Takashi Okamura, Satoshi Iio
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Patent number: 5863606Abstract: Diamond coating member is produced by a method comprising a first coating step in which the first diamond coating layer is closely formed on fine irregularity parts of a substrate having fine irregularities substantially without void left between them and the fine irregularities is engaged with the above first layer to coat the above substrate, and a second coating step in which the surface of the first coating layer is coated with a second diamond coating layer comprising diamond having a higher wear resistance than that of the first coating layer. The diamond coating member is excellent in adhesion between the diamond coating layer and the substrate and has high durability without having the diamond coating layer scaled off by mechanical shocks. It has high wear resistance and enables mass production without fluctuation in product quality.Type: GrantFiled: June 6, 1997Date of Patent: January 26, 1999Assignee: NGK Spark Plug Co., Ltd.Inventors: Takashi Okamura, Takahisa Ushida, Satoshi Iio, Masakazu Watanabe
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Patent number: 5858480Abstract: Ceramic-based substrate for coating, e.g., diamond has a basic irregularities surface having a surface roughness Rz of 2 to 20 .mu.m, with Rz at angle regions of 40% or more of that for other than the angle regions. The basic irregularities surface has micro-sized irregularities on an order of crystal grains constituting the uppermost surface (0.5 to 10 .mu.m), forming dual irregularities surface structure. Coating layer engages with surface irregularities to secure firm adhesion at the cutting edge. WC-based cemented carbide is used as substrate and N-containing surface layer is formed by heat treatment to form the surface irregularities.Type: GrantFiled: September 19, 1996Date of Patent: January 12, 1999Assignee: NGK Spark Plug Co., Ltd.Inventors: Satoshi Iio, Takahisa Ushida, Takashi Okamura, Masakazu Watanabe
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Patent number: 5851658Abstract: A diamond coated article is disclosed which consists essentially of a substrate and a plurality of polycrystalline diamond film layers accumulatively coated thereon in a total thickness of at least 20 .mu.m, wherein each of the polycrystalline diamond film layers (i) has a thickness of 6 to 13 .mu.m, (ii) has an average crystallite size in the surface direction thereof of 3 to 7 .mu.m, (iii) has (111) oriented diamond crystallites exposed on the surface thereof, and (iv) satisfies the relationship: I(N)I(D)<0.2, wherein I(D) represents an intensity of diamond Raman peak in counts/sec appearing around 1333 cm.sup.-1 and I(N) represents a maximum intensity among non-diamond Raman peaks appearing between 1200 cm.sup.-1 and 1600 cm.sup.-1.Type: GrantFiled: July 5, 1996Date of Patent: December 22, 1998Assignee: NGK Spark Plug Co., Ltd.Inventors: Hiroshi Yamamoto, Takashi Okamura, Satoshi Iio
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Patent number: 5843951Abstract: The invention provides an analgesic composition containing as an active ingredient a specific pyrimidine derivative represented by one of the follwing formulas (1) to (3): ##STR1## wherein the substituents are as defined herein. This composition exhibits potent analgesic activity and is effective for alleviating various types of pain such as postoperative pain.Type: GrantFiled: May 21, 1997Date of Patent: December 1, 1998Assignee: Otsuka Pharmaceutical Factory Inc.Inventors: Makoto Inoue, Takashi Okamura, Yasuo Shoji, Kinji Hashimoto, Masayuki Ohara, Tsuneo Yasuda
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Patent number: 5839567Abstract: The present invention relates to a conveying system such as in an assembly line, more particularly to a plurality of transport cars without motor that are driven in close contact with each other on an endless path on guide rails having curved sections, and a friction feeder for moving the transport cars. The cars have a main body and a support for objects to be conveyed. The main body has a plurality of movable bodies and means for coupling the movable bodies to allow a relative yielding motion between the movable bodies at the curved sections in the conveying paths. Driven faces are formed on the movable bodies parallel to the running direction, and a feeder along the conveying path and having a motor driven feed roller that acts on the driven faces of the movable bodies.Type: GrantFiled: January 16, 1996Date of Patent: November 24, 1998Assignee: Daifuku Co., Ltd.Inventors: Hisashi Kyotani, Takashi Okamura, Kiyoshi Hamano
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Patent number: 5725932Abstract: Ceramic-based substrate for coating, e.g., diamond has a basic irregularities surface having a surface roughness Rz of 2 to 20 .mu.m, with Rz at angle regions of 40% or more of that for other than the angle regions. The basic irregularities surface has micro-sized irregularities on an order of crystal grains constituting the uppermost surface (0.5 to 10 .mu.m), forming dual irregularities surface structure. Coating layer engages with surface irregularities to secure firm adhesion at the cutting edge. WC-based cemented carbide is used as substrate and N-containing surface layer is formed by heat treatment to form the surface irregularities.Type: GrantFiled: May 25, 1994Date of Patent: March 10, 1998Assignee: NGK Spark Plug Co., Ltd.Inventors: Satoshi Iio, Takahisa Ushida, Takashi Okamura, Masakazu Watanabe
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Patent number: 5707997Abstract: The invention provides a pyrazolo?1,5-a!pyrimidine derivative of the following formula (1): ##STR1## wherein R.sup.1, R.sup.3, R.sup.4, R.sup.5, R.sup.6, Q, A and n are defined in the description; and R.sup.2 is naphthyl, cycloalkyl, furyl, thienyl, optionally halogen-substituted pyridyl, optionally halogen-substituted phenoxy, or phenyl which may have 1 to 3 substituents selected from the group consisting of lower alkyl, lower alkoxy, halogen, nitro, halogen-substituted lower alkyl, halogen-substituted lower alkoxy, lower alkoxycarbonyl, hydroxyl, phenyl(lower)alkoxy, amino, cyano, lower alkanoyloxy, phenyl and di(lower)alkoxyphos-phoryl(lower)alkyl. This derivative is useful as a potent analgesic.Type: GrantFiled: February 21, 1996Date of Patent: January 13, 1998Assignee: Otsuka Pharmaceutical Factory, Inc.Inventors: Yasuo Shoji, Makoto Inoue, Takashi Okamura, Kinji Hashimoto, Masayuki Ohara, Tsuneo Yasuda
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Patent number: 5705271Abstract: Diamond coating member is produced by a method comprising a first coating step in which the first diamond coating layer is closely formed on fine irregularity parts of a substrate having fine irregularities substantially without void left between them and the fine irregularities is engaged with the above first layer to coat the above substrate, and a second coating step in which the surface of the first coating layer is coated with a second diamond coating layer comprising diamond having a higher wear resistance than that of the first coating layer. The diamond coating member is excellent in adhesion between the diamond coating layer and the substrate and has high durability without having the diamond coating layer scaled off by mechanical shocks. It has high wear resistance and enables mass production without fluctuation in product quality.Type: GrantFiled: April 3, 1995Date of Patent: January 6, 1998Assignee: NGK Spark Plug Co., Ltd.Inventors: Takashi Okamura, Takahisa Ushida, Satoshi Iio, Masakazu Watanabe
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Patent number: 5333982Abstract: A cargo transport system for automated warehousing, wherein there are guide rail structures each mounted from an opposing shelving face structure of two rows of storage shelves extending substantially parallel to each other and present opposing shelving face structures toward one another, each of the guide rail structures including a guide rail with sides, at least one or more power supply conductors, or control signal conductors, or both power supply conductors and control signal conductors disposed substantially parallel to each other and arranged along the side of at least one guide rail, a cargo carrier adapted to roll over the guide rails, and collector attached from the load carrier for maintaining substantially constant electrically conducting contact with the power supply conductors and the control signals conductors for respectively powering and controlling the movement of the cargo carrier.Type: GrantFiled: May 18, 1992Date of Patent: August 2, 1994Assignee: Daifuku Co., Ltd.Inventors: Hideichi Tanizawa, Shuzo Nishino, Takashi Okamura
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Patent number: 5123357Abstract: The present invention is based on the critically important feature of providing a left-right parallel arranged linear motor-based conveying system in which the upper surfaces of the guide rails do double duty as providing the rolling surfaces for the wheel pairs, and also as being secondary (reaction) conductor surfaces for the linear motors, and the linear motors are spaced closely above the upper surfaces of the guide rails by a predetermined clearance.Type: GrantFiled: June 28, 1990Date of Patent: June 23, 1992Assignee: Daifuki Co., Ltd.Inventors: Shigeyoshi Fujita, Naofumi Sekiya, Kazuyoshi Fukuhara, Yoshitaka Watanabe, Takashi Okamura
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Patent number: 5089444Abstract: A method of preparing colored crystallized glass is disclosed, comprising the steps of:(a) adding to a crystallized glass material from 0.1 to 10 parts by weight of a coloring agent per 100 parts by weight of the crystallized glass material, said coloring agent having been prepared by preliminarily burning in an oxidizing atmosphere at a temperature of from 1,000.degree. to 1,400.degree. C. for at least 1 hour from 0.05 to 7 parts by weight of Fe.sub.2 O.sub.3, from 0.03 to 5 parts by weight of CoO, and at least one oxide selected from the group consisting of from 0.01 to 2.5 parts by weight of NiO and from 0.01 to 2.5 parts by weight of Cr.sub.2 O.sub.3, the amounts of the components of the coloring agent being given in parts by weight per 100 parts by weight of the crystallized glass material;(b) molding the resulting mixture under a pressure of from 500 to 3,000 kg/cm.sup.2 ; and(c) calcining the molded mixture to effect crystallization heat treatment.Type: GrantFiled: October 5, 1990Date of Patent: February 18, 1992Assignee: NGK Spark Plug Co., Ltd.Inventors: Masateru Hattori, Takashi Okamura, Kazuo Kondo
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Patent number: 4922830Abstract: A conveyor system comprising a conveyor vehicle, a guide rail for supporting the conveyor vehicle to be freely movable relative thereto, and a linear motor including a primary coil and a secondary conductor for driving the conveyor vehicle. The primary coil is mounted on the conveyor vehicle and the secondary conductor is mounted on the guide rail. The guide rail defines a secondary conductor support portion for limiting downward and transverse movements of the secondary conductor.Type: GrantFiled: December 16, 1988Date of Patent: May 8, 1990Assignee: Daifuku Co., Ltd.Inventors: Shigeyoshi Fujita, Naobumi Sekiya, Takashi Okamura, Yoshitaka Watanabe