Patents by Inventor Takashi Shirai
Takashi Shirai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240125878Abstract: In separating water and fat with applying the Dixon method, peak intensities of fat with multiple peaks are individually calculated with a high degree of accuracy while reducing the number of variables to be estimated. Multiple images made up of signals acquired at different echo times (TEs) are used to solve a predetermined signal equation (signal model) expressing the relation between the pixel values (signal values) of the images and imaging parameters such as signal intensities of components and TE, thereby performing separation of signals for each component. For separating the signals, at least one of the variables (other than the signal intensity) included in the signal equation is subjected to a process (first estimation process) for refining a value roughly obtained, and then using thus refined value of the variable to estimate (second estimation process) other variables (including the signal intensity), the signals are separated.Type: ApplicationFiled: September 22, 2023Publication date: April 18, 2024Inventors: Takashi Nishihara, Toru Shirai, Yoshitaka Bito, Masahiro Takizawa
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Patent number: 11948471Abstract: Provided is a learning assistance technology that uses a learning history to check the level of comprehension by a learner in relation to a learning target.Type: GrantFiled: December 10, 2019Date of Patent: April 2, 2024Assignee: NIPPON TELEGRAPH AND TELEPHONE CORPORATIONInventors: Takashi Hattori, Sanae Fujita, Yoshinari Shirai
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Patent number: 11929589Abstract: A light-emitting component includes: a substrate; plural light-emitting elements that are disposed on the substrate and that emit light in a direction intersecting with a surface of the substrate; and plural thyristors that are stacked on the plural light-emitting elements and that are turned ON to drive the corresponding light-emitting elements so that the light-emitting elements emit light or an amount of light emitted from the light-emitting elements is increased. Each of the plural light-emitting elements includes a current confinement region which is oxidized via a hole provided in a multilayer structure. The multilayer structure is constituted by a corresponding light-emitting element and a corresponding thyristor.Type: GrantFiled: December 20, 2020Date of Patent: March 12, 2024Assignee: FUJIFILM Business Innovation Corp.Inventors: Takashi Kondo, Michiaki Murata, Kenichi Ono, Masahiro Yoshikawa, Takehito Hikichi, Yuji Shirai
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Publication number: 20230219857Abstract: The present invention provides means capable of imparting high temporal stability to a hardening aid solution which serves as a raw material and capable of imparting high strength and high quality stability to a hardened body of the self-hardening material, in the hardened body of the self-hardening material that contains a ceramic powder containing Si element at least on the surface thereof.Type: ApplicationFiled: May 14, 2021Publication date: July 13, 2023Applicants: FUJIMI INCORPORATED, OBAYASHI CORPORATION, NAGOYA INSTITUTE OF TECHNOLOGYInventors: Takashi HAYAKAWA, Naoya MIWA, Keiji ASHITAKA, Takashi HITOMI, Nobuko TAGUCHI, Takashi SHIRAI, Yunzi XIN
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Patent number: 10337900Abstract: A thermal flow meter is provided that can accurately correct zero point and span errors, which change depending on an ambient temperature, independently of a fluid type. The thermal flow meter includes: a flow path through which measuring target fluid flows; an upstream side electrical resistive element provided on the upstream side of the flow path; a downstream side electrical resistive element provided on the downstream side of the flow path; and a flow rate calculation part that calculates a flow rate of the measuring target fluid on the basis of an upstream side voltage that is a voltage applied to the upstream side electrical resistive element, a downstream side voltage that is a voltage applied to the downstream side electrical resistive element, and the thermal conductivity of the measuring target fluid.Type: GrantFiled: September 8, 2014Date of Patent: July 2, 2019Assignee: HORIBA STEC, Co., Ltd.Inventors: Takashi Shirai, Hiroyuki Okano
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Patent number: 10024700Abstract: The present invention is configured to, on the basis of an upstream side parameter having a value that is related to a change rate of an upstream side voltage when a flow rate of measuring target fluid changes, and a downstream side parameter having a value that is related to a change rate of a downstream side voltage when the flow rate of the measuring target fluid changes, calculate a fluid-specific value exhibiting a specific value depending on the thermal conductivity of the fluid.Type: GrantFiled: August 22, 2014Date of Patent: July 17, 2018Assignee: HORIBA STEC, CO., LTD.Inventors: Takashi Shirai, Hiroyuki Okano
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Patent number: 9984794Abstract: A thin and lightweight refractory insulating sheet comprising a refractory bag and a layered type thermal insulator in the bag is disclosed. The layered type thermal insulator comprises a thermal energy consumption layer, a reflector and a graphite layer, and can efficiently attenuate thermal energy by conducting the thermal energy in all directions of the plane even when locally heated, and utilizing the thermal energy for vaporization of the water generated from the thermal energy consumption layer.Type: GrantFiled: November 28, 2017Date of Patent: May 29, 2018Assignee: IMAE INDUSTRY CO., LTD.Inventors: Kenji Imae, Yoshihiko Imae, Takashi Shirai, Naoyuki Oya, Kimihiko Sugiura
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Patent number: 9671182Abstract: The present invention provides a copper alloy tube for heat exchangers which is tolerable to a high operating pressure of new cooling media such as carbon dioxide and HFC-based fluorocarbons, and is excellent in fracture strength, even if the tube is thinned, and a copper alloy tube for a heat exchanger which has a composition having specified amounts of Sn and P, has an average crystal grain size of 30 ?m or less and has a high strength of 250 MPa or more of a tensile strength in the longitudinal direction of the tube improves the fracture strength as a texture in which the orientation distribution density in the Goss orientation is 4% or less.Type: GrantFiled: October 20, 2008Date of Patent: June 6, 2017Assignees: KOBELCO & MATERIALS COPPER TUBE, LTD., Kobe Steel, Ltd.Inventors: Toshiaki Takagi, Yasuhiro Aruga, Mamoru Nagao, Takashi Shirai, Masato Watanabe, Akihiko Ishibashi
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Patent number: 9550834Abstract: The present invention is aimed to provide a method for preparing an acceptor that is N-glycan hydrolyzed antibody or a Fc fragment thereof used for producing antibody having a homogeneous N-glycan structure; a method for determining a combination of endoglycosidases for use in said preparation; and a method for measuring N-glycans linked to an antibody. The present invention is directed to a method for producing a N-glycan hydrolyzed antibody or Fc fragment thereof, comprising reacting the antibody or the Fc fragment thereof with several endoglycosidases; and a method for determining quantitative information of an objective N-glycan with a desired structure linked to an antibody or a Fc thereof, comprising a protease treatment step and a glycopeptide measurement step, etc.Type: GrantFiled: April 17, 2015Date of Patent: January 24, 2017Assignees: THE NOGUCHI INSTITUTE, IMMUNO-BIOLOGICAL LABORATORIES CO., LTD.Inventors: Takashi Shirai, Masako Mori, Masaki Kurogochi, Masahiro Tomita
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Patent number: 9527750Abstract: Hollow nanoparticles having an average particle size of 30 to 300 nm and each including a shell mainly including calcium silicate.Type: GrantFiled: November 9, 2012Date of Patent: December 27, 2016Assignee: NAGOYA INSTITUTE OF TECHNOLOGYInventors: Masayoshi Fuji, Takashi Shirai, Raymond V. Rivera Virtudazo, Chika Takai
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Publication number: 20160131511Abstract: The present invention is configured to, on the basis of an upstream side parameter having a value that is related to a change rate of an upstream side voltage when a flow rate of measuring target fluid changes, and a downstream side parameter having a value that is related to a change rate of a downstream side voltage when the flow rate of the measuring target fluid changes, calculate a fluid-specific value exhibiting a specific value depending on the thermal conductivity of the fluid.Type: ApplicationFiled: August 22, 2014Publication date: May 12, 2016Inventors: Takashi Shirai, Hiroyuki Okano
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Publication number: 20160131512Abstract: A thermal flow meter is provided that can accurately correct zero point and span errors, which change depending on an ambient temperature, independently of a fluid type. The thermal flow meter includes: a flow path through which measuring target fluid flows; an upstream side electrical resistive element provided on the upstream side of the flow path; a downstream side electrical resistive element provided on the downstream side of the flow path; and a flow rate calculation part that calculates a flow rate of the measuring target fluid on the basis of an upstream side voltage that is a voltage applied to the upstream side electrical resistive element, a downstream side voltage that is a voltage applied to the downstream side electrical resistive element, and the thermal conductivity of the measuring target fluid.Type: ApplicationFiled: September 8, 2014Publication date: May 12, 2016Inventors: Takashi Shirai, Hiroyuki Okano
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Publication number: 20160032010Abstract: The present invention is aimed to provide a method for preparing an acceptor that is N-glycan hydrolyzed antibody or a Fc fragment thereof used for producing antibody having a homogeneous N-glycan structure; a method for determining a combination of endoglycosidases for use in said preparation; and a method for measuring N-glycans linked to an antibody. The present invention is directed to a method for producing a N-glycan hydrolyzed antibody or Fc fragment thereof, comprising reacting the antibody or the Fc fragment thereof with several endoglycosidases; and a method for determining quantitative information of an objective N-glycan with a desired structure linked to an antibody or a Fc thereof, comprising a protease treatment step and a glycopeptide measurement step, etc.Type: ApplicationFiled: April 17, 2015Publication date: February 4, 2016Applicants: THE NOGUCHI INSTITUTE, IMMUNO-BIOLOGICAL LABORATORIES CO., LTD.Inventors: Takashi SHIRAI, Masako MORI, Masaki KUROGOCHI, Masahiro TOMITA
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Publication number: 20150331430Abstract: In order to provide an inspection system of a flow sensor capable of charging an appropriate pressure in a flow path in response to the inspection target flow sensor and significantly reducing a waiting time until a start of an inspection, the inspection system is provided with: fluid resistances respectively provided for a plurality of respective branch flow paths branched in a downstream of an upstream side flow path where the inspection target flow sensor is provided: valves respectively provided for the respective branch flow paths; a fluid sensor having at least a part thereof being provided in an upstream side than each of the fluid resistances for measuring a pressure or a flow rate of the fluid; and a valve opening/closing control part configured to allow a plurality of the valves to be in opened states at the time of inspecting the inspection target flow sensor.Type: ApplicationFiled: May 13, 2015Publication date: November 19, 2015Inventors: Tadahiro Yasuda, Takashi Shirai
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Patent number: 9091578Abstract: A thermal flow rate sensor is provided which includes a main flow path through which a fluid flows, and a sensor flow path that branches off from the main flow path so as to cause the fluid to flow in a split flow and that is provided with a flow rate detecting mechanism configured to detect a flow rate of the fluid. The flow rate detecting mechanism includes an upstream-side coil and a downstream-side coil, each configured by using a heat-generating resistance wire wound around a sensor flow pipe forming the sensor flow path. A peak position of a temperature distribution generated in the sensor flow path by the upstream-side coil and the downstream-side coil is positioned on the upstream-side coil side relative to the middle position between the upstream-side coil and the downstream-side coil on the sensor flow path.Type: GrantFiled: December 26, 2012Date of Patent: July 28, 2015Assignee: HORIBA STEC, Co. Ltd.Inventors: Hiroyuki Okano, Takashi Shirai
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Patent number: 8859511Abstract: A method for directly inhibiting proliferation of Helicobacter pylori bacteria, that includes administering to a subject infected with Helicobacter pylori an N-acetylglucosaminyl beta-linked monosaccharide represented by: GlcNAcl-beta-O—Y where Y is an alkyl group, an alkoxyl group, an alkenyl group, an alkynyl group, an aralkyl group, an aryl group, a heteroaryl group, a carboxyl group, or an alkoxycarbonyl group.Type: GrantFiled: January 9, 2013Date of Patent: October 14, 2014Assignee: The Noguchi InstituteInventors: Jun Nakayama, Takashi Shirai, Takashi Yamanoi, Masaya Fujita, Masako Mori
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Publication number: 20140287236Abstract: Hollow nanoparticles having an average particle size of 30 to 300 nm and each including a shell mainly including calcium silicate.Type: ApplicationFiled: November 9, 2012Publication date: September 25, 2014Inventors: Masayoshi Fuji, Takashi Shirai, Raymond V. Rivera Virtudazo, Chika Takai
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Publication number: 20140084203Abstract: An object of the present invention is to provide a method for producing a material for at least any one of an energy device and an electrical storage device, the method being able to form a dense nanostructure, and the material for at least any one of an energy device and an electrical storage device. Disclosed is a method for producing a material for at least any one of an energy device and an electrical storage device, the method including the steps of: treating a raw material including a vitrifiable element with alkali, and solidifying the alkali-treated raw material in a temperature condition of 15 to 30° C.Type: ApplicationFiled: May 16, 2012Publication date: March 27, 2014Applicants: TOYOTA JIDOSHA KABUSHIKI KAISHA, NATIONAL UNIVERSITY CORPORATION NAGOYA INSTITUTE OF TECHNOLOGYInventors: Masayoshi Fuji, Takashi Shirai, Yuki Matsushita
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Patent number: 8575117Abstract: A method for inhibiting proliferation of Helicobacter pylori including a compound that can simply be mass-produced, can specifically inhibit the proliferation of H. pylori, which has high safety and never generates any resistant bacteria, as well as a diet of a food or beverage, and a pharmaceutical preparation containing the proliferation inhibitor of Helicobacter pylori. The proliferation inhibitor of Helicobacter pylori comprises an alpha-N-acetyl-glucosaminyl bond-containing monosaccharide derivative represented by the following chemical formula (1) GlcNAc1-alpha-O—Y ??(1) (in the formula (1), Y is a straight-, branched- or cyclic-aliphatic hydrocarbon group having 1 to 27 carbon atoms or a straight-, branched- or cyclic-acyl group having 1 to 27 carbon atoms). The diet of the food, the beverage or the pharmaceutical preparation comprises the proliferation inhibitor of Helicobacter pylori.Type: GrantFiled: April 9, 2010Date of Patent: November 5, 2013Assignee: The Noguchi InstituteInventors: Jun Nakayama, Takashi Yamanoi, Masaya Fujita, Takashi Shirai
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Patent number: 8562764Abstract: A copper alloy tube according to the present invention includes Sn 0.1 to 2.0 mass %, P 0.005 to 0.1 mass %, S 0.005 mass % or less, O 0.005 mass % or less, and H 0.0002 mass % or less, and the remainder has a composition consisting of Cu and unavoidable impurities. And, as is annealed, the copper alloy tube has the following characteristics: a tensile strength in the longitudinal direction of the copper alloy tube is 250 N/mm2 or more; an average grain diameter is 30 ?m or less when measured in the direction perpendicular to the thickness direction of the tube, in the cross section perpendicular to the tube axis; and assuming that a tensile strength in the longitudinal direction of the copper alloy tube is ?L, and a tensile strength in the circumferential direction of the same is ?T, ?T/?L>0.93 holds.Type: GrantFiled: October 2, 2008Date of Patent: October 22, 2013Assignee: Kobelco & Materials Copper Tube, Ltd.Inventors: Masato Watanabe, Takashi Shirai