Abstract: It is provided a chip having a supporting substrate, a wavelength conversion layer, a base adhesive layer made of an organic resin, an upper-side substrate provided on an upper surface side of the wavelength conversion layer, and an upper-side adhesive layer made of an organic resin for adhering the wavelength conversion layer to the upper-side substrate. The wavelength conversion layer has an optical waveguide with a periodic domain inversion structure provided therein. The chip is heat treated. Anti-reflection films are formed on an incident side end face and projection side end face of the optical waveguide, respectively.

Abstract: A harmonics generating device has a periodic domain inversion structure 18 for converting a wavelength of laser beam to generate higher harmonics. An angle ? formed by a domain inversion plane P of the periodic domain inversion structure 8 and a propagation direction L of the laser beam is from 80 degrees to 89 degrees.

Abstract: A wavelength conversion device 1 includes a supporting body 8, a wavelength conversion substrate 2 of a Z-plate of a ferroelectric single crystal with a periodic domain inversion structure 5 formed therein and having a thickness “T” of 10 ?m or more and 100 ?m or less, a buffer layer 6 provided on a bottom face 2b of the wavelength conversion substrate 2, and an organic resin adhesive layer 7 adhering the supporting body 8 and buffer layer 6 with a thickness of 0.6 ?m or more and 2.0 ?m or less.

Abstract: A harmonic wave oscillating system includes a solid-state laser oscillator, a converting waveguide converting a wavelength of a laser light oscillated from the solid-state laser oscillator to oscillate a harmonic wave, an incident-side end face of the laser light, an emitting-side end face of the harmonic wave, a first side face and a second side face. The emitting-side end face includes a polished surface 6 formed on the side of the first side face 1a and a light scattering surface formed on the side of the second side face 1b. The first side face 1a and polished surface 6 are intersected at an obtuse angle ?, and the second side face 1b and light scattering surface 5 are intersected at an obtuse or right angle ?.

Abstract: The present invention relates to a pyrimidine derivative of the formula (I) and salts thereof which is useful as an active ingredient of pharmaceutical preparations. The pyrimidine derivative of the present invention has excellent CRTH2 (G-protein-coupled chemoattractant receptor, expressed on Th2 cells) antagonistic activity and can be used for the prophylaxis and treatment of diseases associated with CRTH2 activity, in particular for the treatment of allergic diseases, such as asthma, allergic rhinitis, atopic dermatitis, and allergic conjunctivitis; eosinophil-related diseases, such as Churg-Strauss syndrome and sinusitis; basophil-related diseases, such as basophilic leukemia, chronic urticaria and basophilic leukocytosis in human and other mammals; and inflammatory diseases characterized by T lymphocytes and profuse leukocyte infiltrates such as psoriasis, eczema, inflammatory bowel disease, ulcerative colitis, Crohn's disease, COPD (chronic obstructive pulmonary disorder) and arthritis.

Abstract: In a piezoelectric thin film device of the present invention, the degree of flexibility is enhanced in selection of a piezoelectric material constituting a piezoelectric thin film and the crystal orientation in the piezoelectric thin film. A piezoelectric thin film filter, including four film bulk acoustic resonators, has a configuration where a filter section for providing a filter function of the piezoelectric thin film filter is bonded with a flat base substrate mechanically supporting the filter section via an adhesive layer. In manufacturing of the piezoelectric thin film filter, a piezoelectric thin film is obtained by performing removal processing on a piezoelectric substrate, but the piezoelectric thin film obtained by removal processing cannot independently stand up under its own weight. For this reason, a prescribed member including the piezoelectric substrate is previously bonded to the base substrate as a support prior to the removal processing.

Abstract: The present invention relates to a pyrimidine derivative of the formula (I) and salts thereof which is useful as an active ingredient of pharmaceutical preparations. The pyrimidine derivative of the present invention has excellent CRTH2 (G-protein-coupled chemoattractant receptor, expressed on Th2 cells) antagonistic activity and can be used for the prophylaxis and treatment of diseases associated with CRTH2 activity, in particular for the treatment of allergic diseases, such as asthma, allergic rhinitis, atopic dermatitis, and allergic conjunctivitis; eosinophil-related diseases, such as Churg-Strauss syndrome and sinusitis; basophil-related diseases, such as basophilic leukemia, chronic urticaria and basophilic leukocytosis in human and other mammals; and inflammatory diseases characterized by T lymphocytes and profuse leukocyte infiltrates such as psoriasis, eczema, inflammatory bowel disease, ulcerative colitis, Crohn's disease, COPD (chronic obstructive pulmonary disorder) and arthritis.

Abstract: A wavelength converting substrate 1 is made of a Z plate of a ferroelectric single crystal, and includes a periodic domain inversion structure 2 formed therein, an incident face 1c of a fundamental wave 15, an emitting face 1d of a wavelength converted light, a +Z face 1a and a ?Z face 1b. A wavelength converting device 20A has the substrate 1, a first conductive layer 6A formed to contact the +Z face 1a of the substrate 1, and a second conductive layer 6B formed to contact the ?Z face 1b of the substrate 1.

Abstract: A wavelength conversion device 1 has a supporting body 8, a wavelength conversion substrate 2, a lower side buffer layer 6 provided on the side of a bottom face 2b of the substrate 2, a upper side buffer layer 9 provided on the side of a upper face 2a of the substrate 2, and an adhesive layer 7 adhering the supporting body 8 and the lower side buffer layer 6. The wavelength conversion substrate 2 is made of a Z-plate of a ferroelectric single crystal and a periodic polarization inversion structure 5 formed therein. The supporting body 8 has a volume resistivity lower than that of the ferroelectric single crystal of the wavelength conversion substrate 2.

Abstract: A harmonic wave oscillating device 1 has a supporting body 2, a wavelength converting layer 3, an upper side adhesive layer 8 adhering the wavelength converting layer 3 and the supporting body 2, an upper side substrate 5 provided on the side of an upper face of the wavelength converting layer 3, and an upper side adhesive layer 7 adhering the wavelength converting layer 3 and the upper side substrate 5. The wavelength converting layer 3 is made of a ferroelectric single crystal and has a channel type optical waveguide 10 with a periodic polarization inversion structure 11 formed therein. The wavelength converting layer 3 has a width “w” of 1.5 mm or smaller viewed in the direction “A” perpendicular to light propagating in the optical waveguide. At least one of the supporting body 2 and the upper side substrate 5 has a volume resistivity lower than that of the ferroelectric single crystal.

Abstract: The present invention relates to a sulfonamide derivative which is useful as an active ingredient of pharmaceutical preparations. The sulfonamide derivatives of the present invention have CCR3 (CC type chemokine receptor) antagonistic activity, and can be used for the prophylaxis and treatment of diseases associated with CCR3 activity, in particular for the treatment of asthma, atopic dermatitis, allergic rhinitis and other inflammatory/immunological disorders.

Abstract: The present invention relates to an imidazo[1,2-c]pyrimidinylacetic acid derivative and salts thereof which is useful as an active ingredient of pharmaceutical preparations.

Abstract: A composite substrate 10 is a composite substrate in which a piezoelectric substrate 11 that is transparent to light used for photolithography and a supporting substrate 12 for supporting the piezoelectric substrate 11 are bonded together via an organic adhesive layer 13. At least one of the supporting substrate 12 and the organic adhesive layer 13 of the composite substrate 10 can absorb light used for photolithography.

Abstract: A supporting substrate and a piezoelectric substrate are prepared. A surface of the supporting substrate is bonded to the backside of the piezoelectric substrate with an organic adhesive layer interposed therebetween to form a laminated substrate. Subsequently, a peripheral surface of the laminated substrate is ground such that a peripheral surface of the piezoelectric substrate, a peripheral surface of the organic adhesive layer, and a peripheral surface of the supporting substrate on the side of the organic adhesive layer are made flush with each other. Subsequently, the surface of the piezoelectric substrate is polished to reduce the thickness of the piezoelectric substrate and performing mirror polishing of the surface.

Abstract: A wavelength converting device has a substrate made of an electro-optic material and converts a wavelength of a fundamental light to oscillate a converted light. A wavelength converting portion is provided in the substrate and has a cross sectional area of 0.0001 mm2 or larger and 0.01 mm2 or smaller. A pair of thinner portions are provided in both sides of the wavelength converting portion, respectively, and thinner than the wavelength converting portion.

Abstract: A surface acoustic wave device has a supporting substrate 1, a propagation substrate 3A made of a piezoelectric single crystal, an organic adhesive layer 2 having a thickness of 0.1 to 1.0 ?m and bonding the supporting substrate 1 and the propagation substrate 3, and a surface acoustic wave filter provided on the propagation substrate 3A.

Abstract: A wavelength conversion device has a supporting substrate, and a wavelength conversion element provided on the supporting substrate, with separate portions provided on both sides of the wavelength conversion element. The separate portions are separated from the wavelength conversion element by an adhesive layer that bonds the supporting substrate and the wavelength conversion element while also bonding the supporting substrate with the separate portions. The element and separate portions are made of ferroelectric materials, respectively. The wavelength conversion element has a ridge optical waveguide, with grooves provided on each or both sides of the ridge optical waveguide and extended portions provided on the outside of each of the grooves.

Abstract: The present invention relates to a sulfonamide derivative which is useful as an active ingredient of pharmaceutical preparations. The sulfonamide derivatives of the present invention have CCR3 (CC type chemokine receptor) antagonistic activity, and can be used for the prophylaxis and treatment of diseases associated with CCR3 activity, in particular for the treatment of asthma, atopic dermatitis, allergic rhinitis and other inflammatory/immunological disorders.

Abstract: A liquid crystal composition having a nematic phase that includes two components, wherein the first component is a specific four-membered ring compound having a large maximum temperature, and the second component is a specific four-membered ring compound having a large dielectric anisotropy and a large optical anisotropy, and a liquid crystal display device containing the composition.

Abstract: A cladding layer 7 is formed on a base body made of a material for an optical waveguide, and a groove is formed in the base body and the cladding layer 7. The base body and the cladding layer are joined to a supporting substrate with the cladding layer 7 positioned on the said of the supporting substrate 1. The base body is machined and thinned to form a thin plate 30 so that the groove penetrates through the thin plate 30. An end face 14A on the groove 12 side of the optical waveguide 13A is contacted with a light absorbing material or light reflecting material 9 to form a reflecting mirror.