Abstract: The sample imaging apparatus includes: an imaging unit that images a sample by using an achromatic lens in which longitudinal chromatic aberration is corrected in a wavelength range of chemiluminescent light of the sample; an excitation light source (the first epi-illumination light source and/or the second epi-illumination light source) that irradiates the sample with excitation light for causing the sample to emit fluorescent light; and an imaging control unit that adjusts a focal length of the achromatic lens in each imaging in a case of imaging the single sample a plurality of times by changing a wavelength range of the fluorescent light emitted by the sample, and performs imaging in a wavelength order of the fluorescent light used for the imaging.

Abstract: The sample imaging apparatus includes: a housing that forms a closed space; a transparent tray on which a sample is placed in the housing; a plane light source that is formed by using a flat light guide plate, which propagates light emitted by a light emitting element in a plane direction, so as to illuminates the sample with illumination light through the tray in the housing; a lens that is disposed in the housing so as to face the plane light source with the tray interposed between the lens and the plane light source and is used for imaging the sample; and an imaging control unit that adjusts a focal length of the lens and performs imaging in a case of imaging the single sample.

Abstract: The sample imaging apparatus includes: a housing that forms a closed space; a transparent tray on which a sample is placed in the housing; a plane light source that is formed by using a flat light guide plate, which propagates light emitted by a light emitting element in a plane direction, so as to illuminates the sample with illumination light through the tray in the housing; a lens that is disposed in the housing so as to face the plane light source with the tray interposed between the lens and the plane light source and is used for imaging the sample; and an imaging control unit that adjusts a focal length of the lens and performs imaging in a case of imaging the single sample.

Abstract: The sample imaging apparatus includes: an imaging unit that images a sample by using an achromatic lens in which longitudinal chromatic aberration is corrected in a wavelength range of chemiluminescent light of the sample; an excitation light source (the first epi-illumination light source and/or the second epi-illumination light source) that irradiates the sample with excitation light for causing the sample to emit fluorescent light; and an imaging control unit that adjusts a focal length of the achromatic lens in each imaging in a case of imaging the single sample a plurality of times by changing a wavelength range of the fluorescent light emitted by the sample, and performs imaging in a wavelength order of the fluorescent light used for the imaging.

Abstract: Provided is a fluorescence reading device capable of narrowing a distance between a lens unit and an observation object to a distance according to a focal length of a refractive index distribution type lens and focusing fluorescence emitted from the observation object on detecting unit without blurring. Optical fiber sub-bundles equivalent to a light guide unit are buried in lens holding parts of a lens unit. Emission ends of the optical fiber sub-bundles are exposed to upper surfaces of the lens holding parts that face the observation object holding unit. The optical fiber sub-bundles guide the excitation light emitted from the light source and radiate the guided excitation light toward the surface of an observation object that faces the lens unit.

Abstract: In a solid-state laser device and a photoacoustic measurement device including the solid-state laser device, the distance between a laser rod and a flash lamp is narrowed. A shielding lid shields mirrors and an optical path of laser light from the outside. A first portion of a frame body of a laser chamber is exposed from the shielding lid. A flash lamp stored in the frame body of the laser chamber is able to be removed from and inserted into the first portion of the frame body. A thin film portion having a thickness smaller than the thickness of other portions of the shielding lid is provided in at least a part of a region of the shielding lid covering the optical path of a light beam on the outside in a longitudinal direction from the first portion of the frame body of the laser chamber.

Abstract: In a laser device and a photoacoustic measurement device including the laser device, the intensity of light at each wavelength made independently controllable. The laser device includes a laser medium which has oscillation wavelengths at a first wavelength and a second wavelength with higher light emission efficiency than at the first wavelength, an excitation section, a first resonator, a second resonator, a Q-value change unit, and a control section. The control section oscillates light having the first wavelength through Q switching when a first delay time has elapsed after the excitation of the laser medium has been started in a case where the oscillation wavelength is the first wavelength, and oscillates light having the second wavelength through Q switching when a second delay time has elapsed after the excitation of the laser medium has been started in a case where the oscillation wavelength is the second wavelength.

Abstract: Provided is a fluorescence reading device capable of narrowing a distance between a lens unit and an observation object to a distance according to a focal length of a refractive index distribution type lens and focusing fluorescence emitted from the observation object on detecting unit without blurring. Optical fiber sub-bundles equivalent to a light guide unit are buried in lens holding parts of a lens unit. Emission ends of the optical fiber sub-bundles are exposed to upper surfaces of the lens holding parts that face the observation object holding unit. The optical fiber sub-bundles guide the excitation light emitted from the light source and radiate the guided excitation light toward the surface of an observation object that faces the lens unit.

Abstract: Disclosed are a solid-state laser device having an advantage of achieving simplification of a configuration and reduction in size, and a photoacoustic measurement device. In a solid-state laser device which accommodates a solid-state laser medium and an excitation light source having a rod-shaped portion, the excitation light source is provided to be pulled out of a laser chamber. An optical element which bends light is provided at a position separated from the rod-shaped portion such that at least a part of the optical element and at least a part of the rod-shaped portion are at the same position in the longitudinal direction of the rod-shaped portion. One resonator mirror is disposed at a position where bent light is incident. Optical components between the optical element and the resonator mirror are provided at positions separated from a path along which the excitation light source is pulled out.

Abstract: In a solid-state laser device and a photoacoustic measurement device including the solid-state laser device, the distance between a laser rod and a flash lamp is narrowed. A shielding lid shields mirrors and an optical path of laser light from the outside. A first portion of a frame body of a laser chamber is exposed from the shielding lid. A flash lamp stored in the frame body of the laser chamber is able to be removed from and inserted into the first portion of the frame body. A thin film portion having a thickness smaller than the thickness of other portions of the shielding lid is provided in at least a part of a region of the shielding lid covering the optical path of a light beam on the outside in a longitudinal direction from the first portion of the frame body of the laser chamber.

Abstract: In a laser device and a photoacoustic measurement device including the laser device, the intensity of light at each wavelength made independently controllable. The laser device includes a laser medium which has oscillation wavelengths at a first wavelength and a second wavelength with higher light emission efficiency than at the first wavelength, an excitation section, a first resonator, a second resonator, a Q-value change unit, and a control section. The control section oscillates light having the first wavelength through Q switching when a first delay time has elapsed after the excitation of the laser medium has been started in a case where the oscillation wavelength is the first wavelength, and oscillates light having the second wavelength through Q switching when a second delay time has elapsed after the excitation of the laser medium has been started in a case where the oscillation wavelength is the second wavelength.

Abstract: Disclosed are a solid-state laser device having an advantage of achieving simplification of a configuration and reduction in size, and a photoacoustic measurement device. In a solid-state laser device which accommodates a solid-state laser medium and an excitation light source having a rod-shaped portion, the excitation light source is provided to be pulled out of a laser chamber. An optical element which bends light is provided at a position separated from the rod-shaped portion such that at least a part of the optical element and at least a part of the rod-shaped portion are at the same position in the longitudinal direction of the rod-shaped portion. One resonator mirror is disposed at a position where bent light is incident. Optical components between the optical element and the resonator mirror are provided at positions separated from a path along which the excitation light source is pulled out.

Abstract: An X-ray imaging system is provided with an X-ray source (11), first and second absorption gratings (31, 32), and a flat panel detector (FPD) (30), and obtains a phase contrast image of an object H by performing imaging while moving the second absorption grating (32) in x direction relative to the first absorption grating (31). The following mathematical expression is satisfied where p1? denotes a period of a first pattern image at a position of the second absorption grating (32), and p2? denotes a substantial grating pitch of the second absorption grating (32), and DX denotes a dimension, in the x-direction, of an X-ray imaging area of each pixel of the FPD (30). Here, “n” denotes a positive integer.

Abstract: A radiation photographing apparatus 1 includes a radiation irradiating unit 11, a first grating 31 which has a periodic structure which is formed by arranging a plurality of linear bodies 31b and forms a radiation image including a periodic intensity distribution by the passing radiation; a detecting unit 14 which includes a radiation image detector 30 and acquire radiation image data by detecting the radiation image which is irradiated from the radiation irradiating unit to transmit the first grating and a subject and subjected to modulation for the periodic intensity distribution; and a guide unit 70 which guides the arrangement of the subject in relation to an arrangement direction of a group of the linear bodies of the first grating.

Abstract: An X-ray imaging apparatus comprises a first grid, a second grid, and an X-ray image detector. The first grid passes X-rays emitted from an X-ray source and produces a first periodic pattern image. The second grid opposes the first grid. The second grid partly blocks the first periodic pattern image and produces a second periodic pattern image with moiré fringes. The X-ray image detector detects the second periodic pattern image and produces image data. The X-ray image detector has pixels arranged in two dimensions in X and Y directions. The M pixels arranged in the Y direction form one group. The group is shifted in the Y direction by the number of the pixels less than M each time. A phase of an intensity modulated signal, composed of pixel values of the pixels in the each shifted group, is calculated. Thereby a differential phase image is produced.

Abstract: An X-ray imaging apparatus comprises a first grid, a second grid, and an X-ray image detector. The first grid passes X-rays emitted from an X-ray source and produces a first periodic pattern image. The second grid opposes the first grid. The second grid partly blocks the first periodic pattern image and produces a second periodic pattern image with moiré fringes. The X-ray image detector detects the second periodic pattern image and produces image data. The X-ray image detector has pixels arranged in two dimensions in X and Y directions. The M pixels arranged in the Y direction form one group. The group is shifted in the Y direction by the number of the pixels less than M each time. A phase of an intensity modulated signal, composed of pixel values of the pixels in the each shifted group, is calculated. Thereby a differential phase image is produced.

Abstract: An X-ray imaging system includes an X-ray source, first and second absorption gratings, and an FPD. The first absorption grating passes X-ray emitted from the X-ray source to form a G1 image. The second absorption grating modulates intensity of the G1 image at each of relative positions to form two or more fringe images. The relative positions differ in phase with respect to a period pattern of the G1 image. The FPD detects two or more frames of image data of the fringe images. A defective pixel detector reads two or more frames of image data stored in a memory and obtains a characteristic value of an intensity modulated signal on a pixel-by-pixel basis based on the read image data. The defective pixel detector detects a defective pixel based on the characteristic value obtained.

Abstract: A radiographic system which detects a radiation image transmitted through a subject with a radiation image detector and generates a phase contrast image of the subject, includes: a calculation section that calculates a distribution of refraction angles of radiation incident on the radiation image detector and generates the phase contrast image on the basis of the distribution of refraction angles; and a storage section that stores a correction coefficient of each pixel for making sensitivities of pixels equal. The calculation section performs sensitivity correction on a refraction angle of radiation incident on each pixel of the radiation image detector, which is calculated by imaging the subject, using the correction coefficient of the pixel stored in the storage section and generates the phase contrast image of the subject on the basis of the distribution of corrected refraction angles.

Abstract: A radiographic system includes an X-ray source, a first transmission type grating, a second transmission type grating, a scanning mechanism, and a flat panel detector, and an arithmetic processing section. The first transmission type grating is constituted by connecting a plurality of first grating pieces in a first direction, and the second transmission type grating is constituted by connecting a plurality of second grating pieces in the first direction. In projection onto the flat panel detector with the focus of the X-ray source as a viewpoint, at least one pixel is interposed between each pixel of the flat panel detector onto which a connection point of two adjacent first grating pieces is projected and each pixel onto which a connection portion of two adjacent second grating pieces is projected.

Abstract: An X-ray imaging system is provided with an X-ray source (11), first and second absorption gratings (31, 32), and a flat panel detector (FPD) (30), and obtains a phase contrast image of an object H by performing imaging while moving the second absorption grating (32) in x direction relative to the first absorption grating (31). The following mathematical expression is satisfied where p1? denotes a period of a first pattern image at a position of the second absorption grating (32), and p2? denotes a substantial grating pitch of the second absorption grating (32), and DX denotes a dimension, in the x-direction, of an X-ray imaging area of each pixel of the FPD (30). Here, “n” denotes a positive integer.