Abstract: The present invention relates to novel oxazolidinones (Formula I): or a pharmaceutically acceptable salt having ring A characterized by N-containing monocyclic, bicyclic or spirocyclic substituents, to their preparation, and to their use as drugs for treating Mycobacterium tuberculosis and other microbial infections, either alone or in combination with other anti-infective treatments.

Abstract: Provided herein are compounds of Formula (I) as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of tuberculosis.

Abstract: Provided herein are compounds of Formula (I) and Formula (II): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of tuberculosis.

Abstract: Provided herein are compounds of Formula (I) and Formula (II) as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of tuberculosis.

Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of tuberculosis.

Abstract: The present invention relates to novel oxazolidinones (Formula I): or a pharmaceutically acceptable salt having ring A characterized by N-containing monocyclic, bicyclic or spirocyclic substituents, to their preparation, and to their use as drugs for treating Mycobacterium tuberculosis and other microbial infections, either alone or in combination with other anti-infective treatments.

Abstract: The present invention relates to novel oxazolidinones (Formula I): or a pharmaceutically acceptable salt having ring A characterized by N-containing monocyclic, bicyclic or spirocyclic substituents, to their preparation, and to their use as drugs for treating Mycobacterium tuberculosis and other microbial infections, either alone or in combination with other anti-infective treatments.

Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of tuberculosis.

Abstract: The present invention relates to novel oxazolidinones (Formula I): or a pharmaceutically acceptable salt having ring A characterized by N-containing monocyclic, bicyclic or spirocyclic substituents, to their preparation, and to their use as drugs for treating Mycobacterium tuberculosis and other microbial infections, either alone or in combination with other anti-infective treatments.

Abstract: Described herein are compounds and compositions for treating drug resistant and persistent tuberculosis. Also described herein is a method of screening for identifying biofilm formation inhibitors.

Abstract: A lawn mowing vehicle (1) mows a lawn along the travel path of the vehicle. The lawn mowing vehicle (1) includes: at least one electric reel unit having an electric reel (22) raised and lowered by an electric cylinder (26a-26c).

Abstract: A lawn mowing vehicle (1) mows a lawn along the travel path of the vehicle. The lawn mowing vehicle (1) includes: at least one electric reel unit having an electric reel (22) raised and lowered by an electric cylinder (26a-26c); sensors (34a-34c) for detecting the travel speed of the vehicle; sensors for detecting the state of the lawn; and a control device (37) for controlling the electric cylinder (26a-26c) according to the result of the detection by the sensors (34a-34c) to thereby control the elevation position of the electric reel (22) and for controlling whether or not to rotate the electric reel (22) on the basis of the detected results of the sensors for detecting the state of the lawn.

Abstract: A lawn mowing vehicle (1) mows a lawn along the travel path of the vehicle. The lawn mowing vehicle (1) includes: at least one electric reel unit having an electric reel (22) raised and lowered by an electric cylinder (26a-26c); sensors (34a-34c) for detecting the travel speed of the vehicle; and a control device (37) for controlling the electric cylinder (26a-26c) according to the result of the detection by the sensors (34a-34c) to thereby control the elevation position of the electric reel (22).

Abstract: A lawn mowing vehicle (1) mows a lawn along the travel path of the vehicle. The lawn mowing vehicle (1) includes: at least one electric reel unit having an electric reel (22) raised and lowered by an electric cylinder (26a-26c); sensors (34a-34c) for detecting the travel speed of the vehicle; and a control device (37) for controlling the electric cylinder (26a-26c) according to the result of the detection by the sensors (34a-34c) to thereby control the elevation position of the electric reel (22).

Abstract: A lawn moving vehicle (1) is for movwing lawn along the travel path of the vehicle. The lawn moving vehicle (1) includes: at least one electric reel unit having an electric reel (22) driven by a motor (24); sensors (34a-34c) for detecting the travel speed of the vehicle; and a control device (37) for controlling the motor (24) according to the result of the detection by the sensors (34a-34c) to thereby control the rotational speed of the electric reel (22) provided to the electric reel unit.

Abstract: A lawn moving vehicle (1) is for mowing lawn along the travel path of the vehicle. The lawn moving vehicle (1) includes: at least one electric reel unit having an electric reel (22) driven by a motor (24); sensors (34a-34c) for detecting the travel speed of the vehicle; and a control device (37) for controlling the motor (24) according to the result of the detection by the sensors (34a-34c) to thereby control the rotational speed of the electric reel (22) provided to the electric reel unit.

Abstract: A lawn moving vehicle (1) is for movwing lawn along the travel path of the vehicle. The lawn moving vehicle (1) includes: at least one electric reel unit having an electric reel (22) driven by a motor (24); sensors (34a-34c) for detecting the travel speed of the vehicle; and a control device (37) for controlling the motor (24) according to the result of the detection by the sensors (34a-34c) to thereby control the rotational speed of the electric reel (22) provided to the electric reel unit.

Abstract: Macrolide compounds per se, as shown below and defined herein, and their use, e.g., as antibacterial and antiprotozoal agents in animals, including humans: Also disclosed are methods of preparing the compounds, intermediates, and pharmaceutical compositions thereof, and methods of treating or preventing disease by administering the compounds to subjects in need. This abstract is only an excerpt and is not limiting of the invention.

Abstract: This invention relates to compounds of the formula wherein a, R1, R2, R3, R4, R5, R6 and X are each as defined above, and to pharmaceutically acceptable salts thereof, useful as potent antibacterial and antiprotozoal agents that may be used to treat various bacterial and protozoal infections and disorders related to such infections. The invention also relates to pharmaceutical compositions containing the compounds of formula I and to methods of treating bacterial and protozoal infections by administering the compounds of formula I.

Abstract: Macrolide compounds per se, as shown below and defined herein, and their use, e.g., as antibacterial and antiprotozoal agents in animals, including humans: Also disclosed are methods of preparing the compounds, intermediates, and pharmaceutical compositions thereof, and methods of treating or preventing disease by administering the compounds to subjects in need. This abstract is only an excerpt and is not limiting of the invention.