Abstract: Through the present invention, a perimetry result is obtained for a position on a retina surface designated as a position to be tested. As illustrated in the drawing, “the position of a ganglion cell (RGC)” and “the position of a photoreceptor cell (C) for sending information to the ganglion cell (RGC)” are offset on the retina surface (macular part). Here, when position (P1) is designated as a test position for testing the functioning of a ganglion cell at position (P1), the perimeter of the present invention finds “the position (P2) of the photoreceptor cell for sending information to the ganglion cell at position (P1),” presents a visual target at position (P2) rather than position (P1), and tests a visual field. The information of the visual target is sent to the ganglion cell at position (P1), and the functioning of the ganglion cell can therefore be tested.

Abstract: This invention provides an easy-to-tear resin film. Such easy-to-tear resin film is an easy-to-tear, unstretched resin film composed of a blend of a polyethylene terephthalate-based resin with the second resin having a difference in SP value from the polyethylene terephthalate-based resin of 1.1 to 4.0 (cal/cm3)0.5. This invention also provides a laminate film 1B for a packaging material comprising the easy-to-tear, unstretched resin film 10 between the inner layer film 20 serving as a heat seal surface and the surface layer film 30 comprising an isophthalic acid-modified polyethylene terephthalate resin having a copolymerization ratio of isophthalic acid component of 0 mol % to 5 mol %.

Abstract: In a perimetry to be conducted, designating an inspection region through a region designator, a perimeter is configured to set a required time of the perimetry (upper limit time) through an upper limit condition setter and to determine total number or positions of stimulus presentation spots based upon the upper limit time. In such a configuration, an examinee knows the time to finish the inspection, and is able to highly keep his (her) concentration in comparison with a case where the required time is not known, thereby improving precision of the inspection.

Abstract: In a perimetry to be conducted, designating an inspection region through a region designator, stimuli are presented to regions separated in an up/down direction, an oblique direction and a right/left direction from the inspection region (“the spaced region”) in addition to the designated inspection region. At the result, examinees are not able to predict to which of both regions, the inspection region and the spaced region the stimuli are presented, thereby obtaining correct inspection results that do not receive a prediction of the examinees.

Abstract: Electric resistance welded steel pipe excellent in deformability and fatigue properties after quenching which enables working into complicated shapes without spheroidization and which improves the fatigue properties after cold working and quenching without carburization are provided. The electric resistance welded steel pipe is characterized by containing, by mass %, C: 0.15 to 0.55%, Si: 0.01 to 0.30%, Mn: 0.5 to 1.5%, Ca: 0.0010 to 0.0030%, S: 0.0005 to 0.0050%, and O: 0.0005 to 0.0050%, having contents of Ca, O, and S satisfying 0.10?[Ca](1?124[O])/1.25[S]?2.50, having Ca-based inclusions present at the base material and electric resistance weld zone with an average particle size of 1.0 to 10 ?m and a density of 3 to 300/mm2, and having a difference ?Hv of the maximum hardness of the electric resistance weld zone and the average hardness of the base material part satisfying 100 to 500.

Abstract: The present invention provides high strength steel pipe for line pipe superior in low temperature toughness suppressed in drop of toughness of the HAZ and a method of production of the same, more particularly high strength steel plate for line pipe used as a material for high strength steel pipe for line pipe and a method of production of the same, in particular high strength steel pipe for line pipe superior in low temperature toughness characterized in that the chemical compositions of the base metal is, by mass %, C: 0.020 to 0.080%, Si: 0.01 to 0.50%, Mo: 0.01 to 0.15%, Al: 0.0005 to 0.030%, and Nb: 0.0001 to 0.030% contained in a range of C+0.25Si+0.1Mo+Al+Nb: 0.100% or less and the mixture of austenite and martensite present along prior austenite grain boundaries of the reheated part of the heat affected zone has a width of 10 ?m or less and a length of 50 ?m or less.

Abstract: A perimeter 2 for measuring a visual field by conducting perimetry operations regarding measurement points RG of the subject eye 22a has means 17 for storing perimetry result, means 10, 24 for composing the perimetry result as a map image corresponding to a fundus and indicating it on the display 20, means 13 for obtaining and indicating a structure examination image PC1 of the subject eye 22a, means 16 for superimposing the map image MAP2 on the indicated structure examination image PC1 and indicating the superimposed as a composite image PC2, and means 15 for setting a concerned area NA on the composite image PC2, and means 21 for computing an evaluation value of the perimetry based upon the perimetry result.

Abstract: In a perimetry to be conducted, designating an inspection region through a region designator, stimuli are presented to regions separated in an up/down direction, an oblique direction and a right/left direction from the inspection region (“the spaced region”) in addition to the designated inspection region. At the result, examinees are not able to predict to which of both regions, the inspection region and the spaced region the stimuli are presented, thereby obtaining correct inspection results that do not receive a prediction of the examinees.

Abstract: In a perimetry to be conducted, designating an inspection region through a region designator, a perimeter is configured to set a required time of the perimetry (upper limit time) through an upper limit condition setter and to determine total number or positions of stimulus presentation spots based upon the upper limit time. In such a configuration, an examinee knows the time to finish the inspection, and is able to highly keep his (her) concentration in comparison with a case where the required time is not known, thereby improving precision of the inspection.

Abstract: An amplifying circuit according to an embodiment includes a sample and hold circuit, an operational amplifier, a feedback capacitance, and a level shift circuit. The sample and hold circuit includes a sampling capacitance to sample an analog input signal in a sampling phase. The operational amplifier amplifies and outputs the analog input signal held by the sampling capacitance in the amplifying phase. The feedback capacitance is connected between the input terminal of the operational amplifier and the analog output terminal. The level shift circuit includes a level shift capacitance to sample the analog input signal in the sampling phase. A plurality of level shift capacitances is provided and connected in cascade between the output terminal of the operational amplifier and the analog output terminal.

Abstract: A color perception test has a color matching processor that executes a color matching processing on a color monitor, and an image display controller that displays two or more images for color perception test in order on the color monitor on which the color matching processing was done. When displaying each image for color perception test, a color perception test is done in a state that one of its hue, brightness, saturation and display time is changed and the other elements are fixed. Since the color perception tester has the color matching processor, colors of the image are not changed with passage of time different from color printed one, and correct test can be done thereby. If the test is periodically done on some examinee, a degree of decreasing color perception function by aging can be exactly known.

Abstract: Through the present invention, a perimetry result is obtained for a position on a retina surface designated as a position to be tested. As illustrated in the drawing, “the position of a ganglion cell (RGC)” and “the position of a photoreceptor cell (C) for sending information to the ganglion cell (RGC)” are offset on the retina surface (macular part). Here, when position (P1) is designated as a test position for testing the functioning of a ganglion cell at position (P1), the perimeter of the present invention finds “the position (P2) of the photoreceptor cell for sending information to the ganglion cell at position (P1),” presents a visual target at position (P2) rather than position (P1), and tests a visual field. The information of the visual target is sent to the ganglion cell at position (P1), and the functioning of the ganglion cell can therefore be tested.

Abstract: The invention relates to compositions and methods for inhibiting macrophage activation via modulating PARP9 and/or PARP14 expression or activity, such as small molecules, RNAi and antibodies. Modulating the expression and/or activity of PARP9 and/or PARP14 allows the inhibition of monocytes or macrophage M1 activation and inflammation. Inhibiting undesirable excessive or sustained inflammation found in humans, for the treatment, prevention and/or management of conditions where undesirable excessive or sustained inflammation is known or likely to contribute to the onset, development and/or progression the conditions.

Abstract: A perimeter having means for setting a measurement coordinate system CS, a detector for blind spots, a means for measuring a visual field of the same subject eye based on set measurement coordinate systems at a first and second point of time and a memory for storing the position of the blind spot, a detector for detecting the position of the blind spot at the second point of time and computing amount of deviation with the position of the blind spot, and a control for conducting new measurement coordinate based on the deviation (?).

Abstract: [Problem] To increase, compared to conventional devices, the range of motion of the light emitter (fixation lamp) in an external fixation lamp for an ophthalmological instrument and allow movement of the light emitter to arbitrary positions. [Solution] The fixation lamp (1) has a first arm (A1), which supports a light emitter (2) and is supported by a second arm (A2) via a first joint (C1), and is configured so that the first arm (A1) is able to revolve around at least two axes of revolution (E1, E2) by means of the first joint (C1) and said axes of rotation (E1, E2) are not disposed on the same line. Thereby, the range in which the light emitter (2) can be moved can be increased compared to conventional devices and the light emitter can be moved to an arbitrary position in an arbitrary direction.

Abstract: A perimeter 2 for measuring a visual field by conducting perimetry operations regarding measurement points RG of the subject eye 22a has means 17 for storing perimetry result, means 10, 24 for composing the perimetry result as a map image corresponding to a fundus and indicating it on the display 20, means 13 for obtaining and indicating a structure examination image PC1 of the subject eye 22a, means 16 for superimposing the map image MAP2 on the indicated structure examination image PC1 and indicating the superimposed as a composite image PC2, and means 15 for setting a concerned area NA on the composite image PC2, and means 21 for computing an evaluation value of the perimetry based upon the perimetry result.

Abstract: The present invention provides a hot coil for line pipe use which can reduce deviation in ordinary temperature strength and improve low temperature toughness despite the numerous restrictions in production conditions due to the coiling step and provides a method of production of the same, specifically makes the steel plate stop for a predetermined time between rolling passes in the recrystallization temperature range and performs cooling by two stages after hot rolling so as to thereby make the steel structure at the center part of plate thickness and effective crystal grain size of 3 to 10 ?m, make the total of the area ratios of bainite and acicular ferrite 60 to 99%, and make the absolute value of A-B 0 to 30% when the totals of the area ratios of bainite and acicular ferrite at any two portions are designated as respectively A and B.

Abstract: A high-strength welded steel pipe is obtained by welding a seam weld portion of a steel plate that are formed in a pipe shape. In the high-strength welded steel pipe, a base metal of the steel plate includes, by mass %, C: 0.010% to 0.080%, Si: 0.01% to 0.50%, Mn: 0.50% to 2.00%, S: 0.0001% to 0.0050%, Ti: 0.003% to 0.030%, Mo: 0.05% to 1.00%, B: 0.0003% to 0.0100%, O: 0.0001% to 0.0080%, N: 0.006% to 0.0118%, P: limited to 0.050% or less, Al: limited to 0.008% or less, and the balance of Fe and inevitable impurities, Ceq is 0.30 to 0.53, Pcm is 0.10 to 0.20, [N]?[Ti]/3.4 is less than 0.003, the average grain size of the prior ? grains in heat affected zones in the steel plate is 250 ?m or less, and the prior ? grains include bainite and intragranular bainite.

Abstract: The present invention provides a thick welded steel pipe excellent in low temperature toughness in which contents of Mn and Mo satisfy (Expression 1) below, Pcm obtained by (Expression 2) below is 0.16 to 0.19, and a metal structure of a base material steel plate consists of ferrite being 30 to 95% in an area ratio and a low temperature transformation structure, and in a metal structure of a coarse-grained HAZ, an area ratio of grain boundary ferrite is 1.5% or more, the total area ratio of the grain boundary ferrite and intragranular ferrite is not less than 11% nor more than 90%, an area ratio of MA is 10% or less, and its balance is composed of bainite. 1.2325?(0.85×[Mn]?[Mo])?1.5215??(Expression 1) and Pcm=[C]+[Si]/30+([Mn]+[Cu]+[Cr])/20+[Ni]/60+[Mo]/15+[V]/10??(Expression 2).

Abstract: The present invention provides high strength steel pipe for line pipe superior in low temperature toughness suppressed in drop of toughness of the HAZ and a method of production of the same, more particularly high strength steel plate for line pipe used as a material for high strength steel pipe for line pipe and a method of production of the same, in particular high strength steel pipe for line pipe superior in low temperature toughness characterized in that the chemical compositions of the base metal is, by mass %, C: 0.020 to 0.080%, Si: 0.01 to 0.50%, Mo: 0.01 to 0.15%, Al: 0.0005 to 0.030%, and Nb: 0.0001 to 0.030% contained in a range of C+0.25Si+0.1Mo+Al+Nb: 0.100% or less and the mixture of austenite and martensite present along prior austenite grain boundaries of the reheated part of the heat affected zone has a width of 10 ?m or less and a length of 50 ?m or less.