Abstract: An implantable cardiac device comprises a device can and a single lead extending from the device can for cardiac emplacement. The lead senses a first cardiac wave propagating along a first vector and the same cardiac wave propagating along a second vector. The first vector may be between first and second locations on the lead, and the second vector between the lead and the device can or involving other locations on the lead so that a second lead is not needed and it is possible to make a single lead device.

Abstract: Disclosed herein is a device for auricular vagal nerve stimulation in a. subject, said device having an electrode configuration including at least one electrode contact operative to be adhered to a first portion of inner skin surface of an ear Concha of the subject, and at least one return electrode with an opposite polarity operative to be adhered to a second portion of the inner skin surface.

Abstract: The invention is an apparatus and method for Orbital welding of pipes or pipe segments together to form a pipeline, i.e., Orbital welding. A scanner welding unit, a control unit and a welding unit are combined to travel along and above a seam, which is formed between two interfacing base/cylindrical surfaces of every two pipe or pipe segments, scan the pipes/pipe segments relative positioning, alignment and levelling, and their surface geometry and topography and overlay a welding material starting from the root layer at the bottom of the seam and up to its edge and sealing it with a capping layer. The welding unit lowers a welding tip into the seam that may rotate on its axis at different angels relative to the surface during welding. The scanner unit may alert on mismatches on the relative position of the pipes/pipe segments before or after welding and in some cases enable repositioning for a more hermetically sealed weld.

Abstract: The present invention discloses means and methods for performing evaluation of an electrocardiogram (ECG) morphology in an implantable device, optionally the implantable device has a single ECG sensing lead.

Abstract: A method of anti-tachycardia pacing via an implanted cardiac device, comprising: positioning at least one electrode of the implanted cardiac device at an intra-cardiac location; detecting a tachycardia episode; delivering, via the at least one electrode, anti-tachycardia pacing pulses, wherein an anti-tachycardia pacing pulse comprises at least one of: a duration of between 5-10 msec and an amplitude of between 7.5-10V.

Abstract: A method of treating a heart, the method including providing an Implantable Pulse Generator (IPG) adapted to provide a combination of at least two treatment modalities including Cardiac Contractility Modulation therapy and one more modality selected from a group consisting of Cardiac pacing, Cardioversion, Defibrillation, Cardioversion and Defibrillation, and Cardiac Resynchronization Therapy (CRT), detecting a patient's physical condition, and selecting a combination of Cardiac Contractility Modulation therapy and at least one treatment modality from the group, and providing the combination of the Cardiac Contractility Modulation therapy and the at least one treatment modality. Related apparatus and methods are also described.

Abstract: A method of dispensing medication from a plurality of medication containers, using a dispensing system for collecting a medication dosage from a medication container including: receiving a medication selection; selecting a medication container, from the plurality of medication containers, based on the medication selection; matching a collection protocol to be applied to the medication container including one or more parameter for control of the dispensing system; and dispensing the medication selection from the medication container according to the collection protocol.

Abstract: A method of cardiac signal processing including: receiving measurements from at least two electrodes positioned within the heart; determining, using the measurements, relative positioning of the at least two electrodes relative to each other; evaluating suitability of the relative positioning of the at least two electrodes for measurement of cardiac activity to determine which cardiac cycles should receive cardiac contractility modulation stimulation.

Abstract: A device for providing a passage between a first and second heart chamber is provided. The device includes a middle region having first and second ends, a lumen extending therethrough having a longitudinal axis, a first end region coupled to the first end, and a second end region coupled to the second end. The first end region may be delivered in the first heart chamber in a compressed state and transitioned to a deployed state, the first end region being deformable such that portions of the first end region are expandable to different angles relative to the longitudinal axis. The second end region may be delivered in the second heart chamber in a compressed state and transitioned to a deployed state therein, the second end region being deformable such that portions of the second end region are expandable to different angles relative to the longitudinal axis.

Abstract: A neuromodulation system for treatment of physiological disorders. The system includes one or more stimulators for stimulating one or more cranial nerves; one or more detectors configured for detecting a predetermined physiological state; and a control unit that controls nerve stimulation by the one or more stimulators so that it is synchronized with the at least one predetermined physiological state detected by the one or more detectors. A method of neuromodulating a patient for treatment of physiological disorder. The method includes the steps of detecting a predetermined physiological state and applying stimulation to one of the cranial nerves during the predetermined physiological state by one or more stimulators of a neuromodulation system.

Abstract: An improved device delivers a fluid medicament to the subcutaneous tissue of a user. The device is better suited for patients with Parkinson's Disease and other central nervous system disorders, than conventional infusion devices. The device can include a reusable part including a drive component (e.g., motor) and control electronics and a disposable part including a medicament reservoir. Medicament can be evacuated from the medicament reservoir by a plunger assembly that includes a plunger attached to a lead screw that is rotated by a nut, all within the disposable part. The device can be fluidically coupled with the tissue via a flexible cannula. Various embodiments relate to an improved cannula insertion mechanism that delivers the cannula under a force applied by a spring. Various embodiments relate to improved filling of the device, for example, using a vial adapter and an automated filling station.

Abstract: A contraceptive device is provided including an occluding component for deployment in a tubal lumen of a reproductive organ. The device includes an expandable frame reversibly expandable from a collapsed state to an expanded state and a barrier supported by the expandable frame. In the expanded state the barrier is disposed between the expandable frame and walls of the lumen to inhibit in-growth of cellular material into and onto the occluding component, and additionally the barrier is urged against walls of the tubal lumen to define at least two tube lumen sealing areas, disposed perpendicular to a longitudinal axis of the walls of the tube lumen such that (i) the expandable frame is disposed between the two tubal lumen sealing surface, and (ii) passage of reproductive cells through the expandable frame, and through the tube lumen is blocked, therefore, creating a the complete blockage for liquids from a first part of the tube to a second part of the tube, downstream the first part.

Abstract: The present invention relates to methods of distributing pharmaceuticals in a pharmaceutical dispensing system comprising two or more pharmaceutical dispensers configured to store, package and dispense pharmaceuticals in batches according to a schedule and/or immediately dispense non-scheduled pharmaceuticals in response to at least one non-scheduled demand, where some of the pharmaceutical dispensers comprise a limited pharmaceutical storage capacity. The method comprises distributing pharmaceuticals scheduled to be dispensed in batches to one pharmaceutical dispenser and distributing only a subset of non-scheduled pharmaceuticals to another pharmaceutical dispenser.

Abstract: A device for providing a passage between a first and second heart chamber is provided. The device includes a middle region having first and second ends, a lumen extending therethrough having a longitudinal axis, a first end region coupled to the first end, and a second end region coupled to the second end. The first end region may be delivered in the first heart chamber in a compressed state and transitioned to a deployed state, the first end region being deformable such that portions of the first end region are expandable to different angles relative to the longitudinal axis. The second end region may be delivered in the second heart chamber in a compressed state and transitioned to a deployed state therein, the second end region being deformable such that portions of the second end region are expandable to different angles relative to the longitudinal axis.

Abstract: The present invention, in some embodiments thereof, relates to a pharmaceutical dispensing system with dynamic and automatic pharmaceutical dispensing regimes and methods thereof.

Abstract: A pharmaceutical dispensing machine comprising a plurality of modules, said plurality of modules comprise one or more sensors configured to monitor at least one pharmaceutical during a pharmaceutical dispensing process and alert when said at least one pharmaceutical is not detected by at least one of said one or more sensors.

Abstract: An improved device delivers a fluid medicament to the subcutaneous tissue of a user. The device is better suited for patients with Parkinson's Disease and other central nervous system disorders, than conventional infusion devices. The device can include a reusable part including a drive component (e.g., motor) and control electronics and a disposable part including a medicament reservoir. Medicament can be evacuated from the medicament reservoir by a plunger assembly that includes a plunger attached to a lead screw that is rotated by a nut, all within the disposable part. The device can be fluidically coupled with the tissue via a flexible cannula. Various embodiments relate to an improved cannula insertion mechanism that delivers the cannula under a force applied by a spring. Various embodiments relate to improved filling of the device, for example, using a vial adapter and an automated filling station.

Abstract: A neuromodulation system for treatment of physiological disorders. The system includes one or more stimulators for stimulating one or more cranial nerves; one or more detectors configured for detecting a predetermined physiological state; and a control unit that controls nerve stimulation by the one or more stimulators so that it is synchronized with the at least one predetermined physiological state detected by the one or more detectors. A method of neuromodulating a patient for treatment of physiological disorder. The method includes the steps of detecting a predetermined physiological state and applying stimulation to one of the cranial nerves during the predetermined physiological state by one or more stimulators of a neuromodulation system.

Abstract: A medication dispensing system, comprising one or more medication panels, each having a plurality of docking ports located at a vertical displacement one from another. The medication dispensing system comprises: a plurality of medication container assemblies for storing medication, coupled to the plurality of docking ports; one or more actuators; a gripping assembly, movable vertically by the one or more actuators to a proximate one or more of the medication container assemblies for picking a medication dosage out of the one or more of the medication container assemblies; and a receptacle carrier having a receptacle mount for holding one or more medication receptacles configured to receive the medication dosage.

Abstract: Systems and methods are provided for evaluating a Parkinson disease (PD) condition or a progression thereof by using voice analysis, and for treating the PD condition. Evaluation of the PD condition or of the progression thereof may be performed instantly or over time by analyzing current voice samples of the PD subject and, optionally, historical voice samples that are stored in a data storage unit, determining pertinent voice characteristics of the PD subject based on the analysis of the voice samples, and evaluating the PD condition, or the progression thereof by comparing current voice characteristics to similar voice characteristics. Treating a PD condition may include, for example, adjusting a drug delivery parameter to a level that is treatment-wise beneficial, for example, in preventing or delaying the onset of “off” periods or shortening the duration of an “off” period, or ameliorating a Hypokinetic dysarthria (HD) symptom or another PD symptom.