Abstract: The present invention relates to a biologic that inhibits angiogenesis. In particular, the present invention relates to fusion proteins that inhibit the integrin activated pathway and one other angiogenic factor-activated pathway as well as formulation compositions of such fusion proteins, as well as methods for producing and using the same.

Abstract: A spectroscopic metrology system includes a spectroscopic metrology tool and a controller. The controller generates a model of a multilayer grating including two or more layers, the model including geometric parameters indicative of a geometry of a test layer of the multilayer grating and dispersion parameters indicative of a dispersion of the test layer. The controller further receives a spectroscopic signal of a fabricated multilayer grating corresponding to the modeled multilayer grating from the spectroscopic metrology tool. The controller further determines values of the one or more parameters of the modeled multilayer grating providing a simulated spectroscopic signal corresponding to the measured spectroscopic signal within a selected tolerance. The controller further predicts a bandgap of the test layer of the fabricated multilayer grating based on the determined values of the one or more parameters of the test layer of the fabricated structure.

Abstract: Various embodiments of a laser driver are described herein. In an embodiment, a laser driver system includes: an external set of inductors including a first external inductor and a second external inductor; an internal set of inductors including a first internal inductor and a second internal inductor; and a DC-to-DC convertor configured to bias a first output path defined by the first external inductor and the first internal inductor and a second output path defined by the second external inductor and the second internal inductor.

Abstract: An electronic device may have a display with an array of display pixels. To increase the efficiency of the display, the display may also include an array of microlenses. Each microlens may overlap and focus light from a respective pixel. Pixels for one of the colors of light may have a high aspect ratio. These pixels may be covered by two microlenses or a single cylindrical microlens. The microlens dimensions may be tuned to mitigate non-uniformities in the brightness profiles of the pixels. The microlens edges may be laterally shifted towards or away from the center of the light-emitting areas to either reduce or increase the focusing power of the microlens. The microlenses and color filter elements in each pixel may also be shifted to account for the chief ray angle of the display.

Abstract: Source code routines are generated for storage management in a storage code development management tool. A script that includes the source code routines is generated. The storage code development management tool receives indications based on an execution of an object code generated via execution of the script. The storage code development management tool modifies the source code routines based on the received indications.

Abstract: Provided are methods and systems for traversing a data model with a plurality of workers to generate a plurality of virtual records for use in evaluating an expression by a plurality of aggregators. Each aggregator may receive a respective virtual record and evaluate a hypercube function and determine a respective hash based on the respective virtual record. The virtual records based on the respective hash values of the respective virtual records may be stored by the plurality of aggregators.

Abstract: In an aspect, provided is a method for targeted extraction of data satisfying a query. The method can rely upon one or more data structures indicative of data values satisfying or not satisfying one or more filters. Only the data indicated as satisfying (or as not satisfying) the data in a data structure related to the query are extracted. The extracted data may then be sorted.

Abstract: A method includes receiving a seismic data volume comprising seismic information of subterranean formations and receiving a set of seismic traces of the seismic data volume. The method also includes, determining, along each seismic trace of the set of seismic traces, a set of seed points comprising minimum or maximum onsets. Further, the method includes sorting the set of seed points into a sorted set of seed points by absolute amplitude values of the set of seed points. Furthermore, the method includes generating a horizon representation of every seismic event in the seismic data volume by automatically tracking horizons throughout an entirety of the seismic data volume from the sorted set of seed points in an order of the absolute amplitude values of the sorted set of seed points. Additionally, the method includes generating a graphical user interface that includes the horizon representation for display on a display device.

Abstract: The present invention relates to a biologic that inhibits angiogenesis. In particular, the present invention relates to fusion proteins that inhibit the integrin activated pathway and one other angiogenic factor-activated pathway as well as formulation compositions of such fusion proteins, as well as methods for producing and using the same.

Abstract: In an aspect, provided is a method comprising receiving, at a master node, capability information associated with a plurality of worker nodes, receiving, at the master node, an indexation request, and in response to the indexation request, distributing one or more tasks to the plurality of worker nodes based on the respective capability information, wherein the one or more tasks relate to generating a plurality of indexlets.

Abstract: A portable cargo carrying assembly includes a cargo carrier that has a hitch engagement such that the hitch engagement is attachable to a hitch receiver of a vehicle to transport cargo. The cargo carrier has a pair of handles each is integrated into the cargo carrier thereby facilitating the cargo carrier to be carried by a user. A plurality of support legs is each pivotally attached to the cargo carrier. Each of the support legs is positionable in a stored position when the cargo carrier is attached to the vehicle. Each of the support legs is positionable in a deployed position when the cargo carrier is detached from the vehicle thereby facilitating the support legs to support the cargo carrier above a support surface such that the cargo carrier defines a table.

Abstract: In an aspect, provided is a method comprising receiving, at a master node, capability information associated with a plurality of worker nodes, receiving, at the master node, an indexation request, and in response to the indexation request, distributing one or more tasks to the plurality of worker nodes based on the respective capability information, wherein the one or more tasks relate to generating a plurality of indexlets.

Abstract: Disclosed are systems and methods for extracting and visualizing patterns in large-scale data sets. A data set comprising a plurality of data points is received. A plurality of connections between the plurality of data points is generated. Based on the plurality of connections, a plurality of groups from the plurality of data points is generated. A visual analytic comprising a plurality of geometrical shapes corresponding to the plurality of groups is generated.

Abstract: Disclosed are systems and methods for extracting and visualizing patterns in large-scale data sets. A data set comprising a plurality of data points is received. A plurality of connections between the plurality of data points is generated. Based on the plurality of connections, a plurality of groups from the plurality of data points is generated. A visual analytic comprising a plurality of geometrical shapes corresponding to the plurality of groups is generated.

Abstract: Ophthalmic formulations containing nintedanib, or a pharmaceutically acceptable salt thereof are provided. The ophthalmic formulations can contain microparticles or nanoparticles of nintedanib. Also provided are methods of using the ophthalmic formulations for treating ocular surface diseases, such as dry eye disease.

Abstract: Ophthalmic formulations containing nintedanib, or a pharmaceutically acceptable salt thereof are provided. The ophthalmic formulations can contain microparticles or nanoparticles of nintedanib. Also provided are methods of using the ophthalmic formulations for treating ocular surface diseases, such as dry eye disease.

Abstract: In an aspect, provided is a method comprising receiving, at a master node, capability information associated with a plurality of worker nodes, receiving, at the master node, an indexation request, and in response to the indexation request, distributing one or more tasks to the plurality of worker nodes based on the respective capability information, wherein the one or more tasks relate to generating a plurality of indexlets.

Abstract: The present invention relates to a biologic that inhibits angiogenesis. In particular, the present invention relates to fusion proteins that inhibit the integrin activated pathway and one other angiogenic factor-activated pathway, the compositions of these fusion proteins, as well as methods for producing and using the same.

Abstract: Methods, systems and apparatus for detecting object location and generating alerts are disclosed herein. An example disclosed method includes determining an assigned area for an object being handled by a loader; detecting a first location of the loader; determining whether the first location corresponds to the assigned area for the object; and in response to the first location not corresponding to the assigned area for the object, generating a first output indicative of a difference between the first location and the assigned area for the object.

Abstract: In an aspect, provided is a method comprising receiving, at a master node, capability information associated with a plurality of worker nodes, receiving, at the master node, an indexation request, and in response to the indexation request, distributing one or more tasks to the plurality of worker nodes based on the respective capability information, wherein the one or more tasks relate to generating a plurality of indexlets.