Abstract: The present invention discloses a pyrimidine heterocyclic compound, and a preparation method and medical use thereof. Specifically, the present invention discloses a pyrimidine heterocyclic compound with a structure shown in Formula (A) or a pharmaceutically acceptable salt thereof (groups are each defined in the specification), a pharmaceutical composition comprising the compound, and use of the compound in treatment of cell proliferative diseases (such as cancers).

Abstract: This application provides an on board power supply apparatus and an electric vehicle, which effectively resolves problems of easy damage to a switch circuit and a waste of electrical energy due to repeated turn-on of the switch circuit. The on board power supply apparatus includes a first power conversion circuit and a switch module. The switch module includes a driver, a switch assembly, and a latch circuit. A low-voltage load is configured to receive the low-voltage direct current or receive an output voltage of a low-voltage power supply through the switch assembly. When the low-voltage power supply supplies power to the low-voltage load through the switch assembly, in response to a turn-off signal output by the latch circuit, the driver controls the switch assembly to break a connection between the low-voltage power supply and the low-voltage load until the latch circuit stops outputting the turn-off signal.

Abstract: Embodiments of this application provide a voltage conversion circuit, a control method, a DC/DC converter and a device. The voltage conversion circuit includes a failure isolation module, a soft start module, and a voltage conversion module. The voltage conversion module includes an output filter capacitor. Both a first terminal of the failure isolation module and a first terminal of the soft start module are connected to a positive electrode of a first battery, both a second terminal of the failure isolation module and a second terminal of the soft start module are connected to a first terminal of the output filter capacitor, and a second terminal of the output filter capacitor is connected to a negative electrode of the first battery. The soft start module is configured to connect the first battery and the output filter capacitor, so that the first battery charges the output filter capacitor.

Abstract: An electrode assembly, a secondary battery, and a battery-powered apparatus. The electrode assembly includes a negative electrode plate, a positive electrode plate, and a separator, and the negative electrode plate, the separator, and the positive electrode plate are laminated and wound around a winding center, where the negative electrode plate includes a first inner layer section, the positive electrode plate includes a second inner layer section, and the first inner layer section and the second inner layer section are immediately adjacent to the winding center; and the first inner layer section is provided with a notch portion, and the first inner layer section is disposed opposite the second inner layer section through the notch portion.

Abstract: The present invention relates to Compounds of Formula (I) and pharmaceutically acceptable salts or prodrug thereof. The present invention also relates to compositions comprising at least one compound of Formula (I), and methods of using the compounds of Formula (I) for treatment or prophylaxis of lysosomal storage diseases, neurodegenerative disease, cystic disease, cancer, or a diseases or disorders associated with elevated levels of glucosylceramide (GlcCer), glucosylsphingosine (GlcSph) and/or other glucosylceramide-based glycosphingolipids (GSLs).

Abstract: Provided are an ROR?t modulator, and a preparation method therefor and an application thereof. The ROR?t modulator is selected from a compound represented by formula I, and a pharmaceutically acceptable salt, solvate, solvate of pharmaceutically acceptable salt, metabolite or prodrug thereof. The compound has inhibitory activity on ROR?t, and can effectively inhibit an ROR?t protein receptor, thereby regulating the differentiation of Th17 cells, inhibiting generation of IL-17, and then treating ROR?t-mediated relevant autoimmune diseases.

Abstract: A packaging structure is provided and may include a housing and a power component. The power component is disposed inside the housing. The housing may include a top cover and a bottom housing. The top cover may have a first heat transfer medium channel inside. The bottom housing may have a second heat transfer medium channel inside. The power component may include a first circuit board and a second circuit board. At least one first heating device may be disposed on the first circuit board. The first heating device may press against an inner wall of the top cover. At least one second heating device may be disposed on the second circuit board, and the second heating device may press against an inner wall of the bottom housing. When the foregoing structure is used, high power density and high heat dissipation efficiency can be achieved.

Abstract: In accordance with an embodiment an apparatus, includes: a power conversion circuit having: a power port configured to receive power from an external power supply, a first direct current port configured to output a first direct current, a second direct current port configured to output a second direct current, wherein a voltage of the second direct current port is configured to be higher than a voltage of the first direct current port, an upper-layer printed circuit board (PCB) electrically connected to the second direct current port, and a lower-layer PCB electrically connected to the first direct current port and to the power port; a bottom housing; and a heat sink, wherein the lower-layer PCB, the upper-layer PCB, and the heat sink are sequentially stacked in and fastened to the bottom housing.

Abstract: A lens forming method is provided, including: heating a blank mold with a pre-molding cavity until a glass preform in the pre-molding cavity is in a semi-molten state; applying a pressure to the blank mold, so that the glass preform is extruded to form a lens rough blank with a predetermined shape; cooling the blank mold and the lens rough blank, and separating the blank mold by depressurization, to transfer the lens rough blank to a molding cavity of a high-precision aspherical mold; heating the high-precision aspherical mold until the lens rough blank is softened to a semi-molten state; applying a pressure to the high-precision aspherical mold, so that the lens rough blank is extruded to form a lens molded part with an aspherical structure; and cooling the high-precision aspherical mold and the lens molded part, and separating the high-precision aspherical mold by depressurization, to remove the lens molded part.

Abstract: The present disclosure belongs to the technical field of hydraulic control, and relates to a velocity and position compound control system for a pump-valve dual-source driven hydraulic cylinder used in engineering machinery. The system includes a first power source, a first hydraulic pump, a second power source, a second hydraulic pump, a safety valve, a proportional directional valve, a pilot operated check valve, a single-rod hydraulic cylinder, a handle, a tank, a rotating speed sensor, a first pressure sensor, a second pressure sensor, a third pressure sensor, a temperature sensor, a position transmitting unit, magnetic induction marks, a count correction module, an integrator module, a calculation control module, a signal acquisition module, a data storage module, a cloud memory, a communication protocol module, a fault diagnosis module, and a process monitoring module.

Abstract: A vehicle-mounted charging apparatus and a vehicle. The vehicle-mounted charging apparatus includes a power conversion circuit and a housing. The housing is configured to accommodate the power conversion circuit. The power conversion circuit is configured to convert an input power supply into at least one of a first direct current or a second direct current. A plurality of electrical interfaces is disposed on an electrical interface mounting surface in the housing. The plurality of electrical interfaces includes one input power interface, two first direct current output interfaces, and one second direct current output interface. The input power interface is configured to be connected to an input end of the power conversion circuit. The plurality of electrical interfaces is disposed on a same surface, so that the external interfaces are appropriately arranged and highly integrated. This facilitates a vehicle layout, improves assembly simplicity.

Abstract: An independent eye-mounted device includes a display that projects pixels onto a retina of a user's eye. The device also includes a memory storing an application, and a processing device coupled to the memory to execute the application. The application populates a canvas with images of rendered graphic objects used by the application. The device further includes a real-time graphics module that, repeatedly and in real-time, transfers the images of the rendered graphic objects from the canvas to the display.

Abstract: A heat management system includes a first heat exchanger, a second heat exchanger, a heat pump, an electric assembly waterway, a radiator waterway, a battery waterway, and a heat exchange waterway. The heat pump module includes a first heat exchange pipeline and a second heat exchange pipeline. A first heat exchange passage and a second heat exchange passage of the first heat exchanger are respectively disposed on the second heat exchange pipeline and the heat exchange waterway. A third heat exchange passage of the second heat exchanger is disposed on the first heat exchange pipeline, and a fourth heat exchange passage of the second heat exchanger is in communication with the radiator waterway. The radiator waterway and the electric assembly waterway may be in communication in series.

Abstract: A method for electric field measurement based on a levitated particle includes steps of (1) capturing a particle and levitating the captured particle; (2) adjusting a quantity of electric charge carried by the levitated particle; (3) measuring a charge number N of the levitated particle; (4) disposing the levitated particle in an electric field to be measured, measuring a displacement power spectral density Svxel of the levitated particle under the electric field and obtaining an electric field force Fel; and (5) according to a formula of E=Fel/Nqe, obtaining an electric field intensity E. An apparatus for electric field measurement based on a levitated particle includes a high-voltage DC (direct current) power supply, two bare wire electrodes, a vacuum chamber, a trapping laser, an objective lens, a pair of parallel electrodes, a collective lens, a quadrant photodetector, a lock-in amplifier, a signal generator and a power amplifier.

Abstract: Embodiments of this application provide a voltage conversion circuit, a control method, a DC/DC converter and a device. The voltage conversion circuit includes a failure isolation module, a soft start module, and a voltage conversion module. The voltage conversion module includes an output filter capacitor. Both a first terminal of the failure isolation module and a first terminal of the soft start module are connected to a positive electrode of a first battery, both a second terminal of the failure isolation module and a second terminal of the soft start module are connected to a first terminal of the output filter capacitor, and a second terminal of the output filter capacitor is connected to a negative electrode of the first battery. The soft start module is configured to connect the first battery and the output filter capacitor, so that the first battery charges the output filter capacitor.

Abstract: Disclosed are high-precision-map data collection methods, devices and storage mediums, which relate to the field of computer technologies, and particularly to the fields of big data technologies, autonomous driving technologies, intelligent transportation technologies, or the like. The data collection method includes: receiving a collection task generated by a server, where the collection task includes to-be-collected track points; generating a navigation path based on the to-be-collected track points, and displaying the navigation path; and acquiring map data collected at the to-be-collected track points when a vehicle travels based on the navigation path.

Abstract: A method for electric field measurement based on a levitated particle includes steps of (1) capturing a particle and levitating the captured particle; (2) adjusting a quantity of electric charge carried by the levitated particle; (3) measuring a charge number N of the levitated particle; (4) disposing the levitated particle in an electric field to be measured, measuring a displacement power spectral density Svxel of the levitated particle under the electric field and obtaining an electric field force Fel; and (5) according to a formula of E=Fel/Nqe, obtaining an electric field intensity E. An apparatus for electric field measurement based on a levitated particle includes a high-voltage DC (direct current) power supply, two bare wire electrodes, a vacuum chamber, a trapping laser, an objective lens, a pair of parallel electrodes, a collective lens, a quadrant photodetector, a lock-in amplifier, a signal generator and a power amplifier.

Abstract: A main body structure of a submarine stratum space cable laying robot includes one telescopic electric linear actuator unit including two dustproof sleeves with one sleeved on the other, and four single supporting arm units for forward motion and supporting. Two ends of each single supporting arm unit are sequentially provided with rotating supporting plates, reducers, motors and connecting flanges from inside to outside, and an outside of each single supporting arm unit is provided with a rotating plate structure. The single supporting arm units in each group are movably connected by the adjacent ends and movably connected to connectors of the telescopic electric linear actuator unit by respective outer ends thereof. The two groups of single supporting arm units connected in series are symmetrically arranged, such that a whole main body structure of the robot is diamond-shaped.

Abstract: The present disclosure provides a method and system for controlling a deposition device, relating to the field of semiconductor technology. The method for controlling a deposition device is applied to the deposition device, the deposition device includes a reaction chamber and an electrostatic chuck arranged in the reaction chamber, the electrostatic chuck carries a wafer, and the controlling method includes: obtaining a pressure value between the wafer and the electrostatic chuck; and when the pressure value exceeds a preset range, the deposition device sending out an alarm signal, and executing a cleaning operation according to a use state of the electrostatic chuck.