Patents by Inventor Tao Xin

Tao Xin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9529852
    Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for selecting a template for a content item. In one aspect, a method includes receiving a content item request that includes context data. A content item that is eligible to be presented in response to the content item request is identified. A determination is made that the content item includes a template variable that is resolved based on the context data. A template feed including a set of templates is identified based on the template variable. A template is selected from the template feed for the content item. The template can be selected based on the context data. The selected template is populated with content for the content item to create a formatted content item. The formatted content item is provided in response to the content item request.
    Type: Grant
    Filed: August 11, 2015
    Date of Patent: December 27, 2016
    Assignee: Google Inc.
    Inventors: Stephen Tsun, Jayavel Shanmugasundaram, Tao Xin
  • Publication number: 20160083346
    Abstract: Compounds of Formula I which are derivatives of 3-Hydroxypyridin-4-ones. The compounds may be used in treatment of a medical condition related to a toxic concentration of iron. The compounds may be used for preparation of a medicament for treatment of a medical condition related to a toxic concentration of iron. The medical condition related to a toxic concentration of iron may be selected from the group consisting of: cancer, pulmonary disease, progressive kidney disease and Friedreich's ataxia.
    Type: Application
    Filed: December 1, 2015
    Publication date: March 24, 2016
    Inventors: Tim Fat Tam, Regis Leung-Toung, Yingsheng Wang, Yanqing Zhao, Tao Xin, Birenkumar Shah, Blaise N'Zemba, Jolanta Maria Wodzinska, Maryna Premyslova
  • Publication number: 20150335626
    Abstract: Provided are compounds of Formula I which are derivatives of 3-Hydroxypyridin-4-ones. The compounds may be used in treatment of a medical condition related to a toxic concentration of iron. The compounds may be used for preparation of a medicament for treatment of a medical condition related to a toxic concentration of iron. The medical condition related to a toxic concentration of iron may be selected from the group consisting of: cancer, pulmonary disease, progressive kidney disease and Frederich's Ataxia.
    Type: Application
    Filed: June 10, 2015
    Publication date: November 26, 2015
    Inventors: Tim Fat TAM, Regis LEUNG-TOUNG, Yingsheng WANG, Yanqing ZHAO, Tao XIN, Birenkumar SHAH, Blaise N'ZEMBA, Jolanta Maria WODZINSKA, Maryna PREMYSLOVA
  • Publication number: 20150274665
    Abstract: Provided are compounds of Formula I which are derivatives of 3-Hydroxypyridin-4-ones. The compounds may be used in treatment of a medical condition related to a toxic concentration of iron. The compounds may be used for preparation of a medicament for treatment of a medical condition related to a toxic concentration of iron. The medical condition related to a toxic concentration of iron may be selected from the group consisting of: cancer, pulmonary disease, progressive kidney disease and Frederich's Ataxia.
    Type: Application
    Filed: June 11, 2015
    Publication date: October 1, 2015
    Inventors: Tim Fat TAM, Regis LEUNG-TOUNG, Yingsheng WANG, Yanqing ZHAO, Tao XIN, Birenkumar SHAH, Blaise N'ZEMBA, Jolanta Maria WODZINSKA, Maryna PREMYSLOVA, Jianmin Zhang
  • Patent number: 9135292
    Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for selecting a template for a content item. In one aspect, a method includes receiving a content item request that includes context data. A content item that is eligible to be presented in response to the content item request is identified. A determination is made that the content item includes a template variable that is resolved based on the context data. A template feed including a set of templates is identified based on the template variable. A template is selected from the template feed for the content item. The template can be selected based on the context data. The selected template is populated with content for the content item to create a formatted content item. The formatted content item is provided in response to the content item request.
    Type: Grant
    Filed: April 8, 2013
    Date of Patent: September 15, 2015
    Assignee: Google Inc.
    Inventors: Stephen Tsun, Jayavel Shanmugasundaram, Tao Xin
  • Patent number: 9073865
    Abstract: Provided are compounds of Formula I which are derivatives of 3-Hydroxypyridin-4-ones. The compounds may be used in treatment of a medical condition related to a toxic concentration of iron. The compounds may be used for preparation of a medicament for treatment of a medical condition related to a toxic concentration of iron. The medical condition related to a toxic concentration of iron may be selected from the group consisting of: cancer, pulmonary disease, progressive kidney disease and Frederich's Ataxia.
    Type: Grant
    Filed: July 5, 2010
    Date of Patent: July 7, 2015
    Assignee: Apotex Technologies Inc.
    Inventors: Tim Fat Tam, Regis Leung-Toung, Yingsheng Wang, Yanqing Zhao, Tao Xin, Birenkumar Shah, Blaise N'Zemba, Jolanta Maria Wodzinska, Maryna Premyslova
  • Publication number: 20150011484
    Abstract: The present invention provides pro-drugs of D-gamma-glutamyl-[D/L]-tryptophan, said pro-drugs are compounds of Formula I or pharmaceutically acceptable salts thereof, wherein G is C1-C8 alkyl or benzyl, T is C1-C8 alkyl or benzyl, and * is a chiral carbon in a (R) or (S) configuration, provided that when * is in the (R) configuration, at least one of G and T is C5-C8 alkyl; and use of compounds of Formula I in a pharmaceutical composition.
    Type: Application
    Filed: March 30, 2012
    Publication date: January 8, 2015
    Applicant: APTOEX TECHNOLOGIES, INC.
    Inventors: Tim Fat Tam, Regis Leung-Toung, Yinsheng Wang, Yanqing Zhao, Tao Xin, Wanren Li, Jolanta Maria Wodzinska, Vrajlal S. Rabadia, Birenkumar Shah, Christopher John Feeney
  • Publication number: 20140343050
    Abstract: Provided are carboxylic ester derivatives of formula (I), methods of preparing them, and methods for using them. These compounds are prodrugs of D-isoglutamyl-[D/L]-tryptophan. The in vitro bioconversion of some of the prodrugs to the parent drug D-isoglutamyl-D-tryptophan (or thymodepressin) was tested in human hepatocytes and in human blood. In vivo pharmacokinetic studies following oral administration of some of the prodrugs to rats are also reported.
    Type: Application
    Filed: March 30, 2012
    Publication date: November 20, 2014
    Applicant: APTOEX TECHNOLOGIES, INC.
    Inventors: Tim Fat Tam, Regis Leung-Toung, Yingsheng Wang, Yanqing Zhao, Tao Xin, Wanren Li, Jolanta Maria Wodzinska, Vrajlal S. Rabadia, Christopher John Feeney
  • Publication number: 20120302596
    Abstract: Described herein are compounds with affinity for the 5-HT6 receptor, which have the general formula I: wherein A, B, D, E, R1 to R3 and n are described herein. Also described is the use of these compounds as pharmaceuticals to treat indications where inhibition of the 5-HT6 receptor is implicated, such as schizophrenia.
    Type: Application
    Filed: March 1, 2012
    Publication date: November 29, 2012
    Applicant: NPS Pharmaceuticals, Inc.
    Inventors: Louise Edwards, Abdelmalik Slassi, Ashok Tehim, Tao Xin
  • Publication number: 20120270882
    Abstract: Provided are compounds of Formula I which are derivatives of 3-Hydroxypyridin-4-ones. The compounds may be used in treatment of a medical condition related to a toxic concentration of iron. The compounds may be used for preparation of a medicament for treatment of a medical condition related to a toxic concentration of iron. The medical condition related to a toxic concentration of iron may be selected from the group consisting of: cancer, pulmonary disease, progressive kidney disease and Frederich's Ataxia.
    Type: Application
    Filed: July 5, 2010
    Publication date: October 25, 2012
    Applicant: APOTEX TECHNOLOGIES INC.
    Inventors: Tim Fat Tam, Regis Leung-Toung, Yingsheng Wang, Yangqing Zhao, Tao Xin, Birenkumar Shah, Blaise N'zemba, Jolanta Maria Wodzinska, Maryna Premyslova
  • Publication number: 20120157387
    Abstract: Provided are compounds which are prodrugs of D-gamma-glutamyl-D-tryptophan, methods of making the compounds and methods for using the compounds.
    Type: Application
    Filed: February 20, 2012
    Publication date: June 21, 2012
    Applicant: APOTEX TECHNOLOGIES INC.
    Inventors: Tim Fat TAM, Regis Leung-Toung, Yingsheng Wang, Yanqing Zhao, Tao Xin, Wanren Li, Jolanta Maria Wodzinska, Vrajlal S. Rabadia, Birenkumar Shah, Christopher John Feeney
  • Patent number: 8148394
    Abstract: Described herein are compounds with affinity for the 5-HT6 receptor, which have the general formula I: wherein A, B, D, E, R1 to R3 and n are described herein. Also described is the use of these compounds as pharmaceuticals to treat indications where inhibition of the 5-HT6 receptor is implicated, such as schizophrenia.
    Type: Grant
    Filed: August 7, 2007
    Date of Patent: April 3, 2012
    Assignee: NPS Pharmaceuticals, Inc.
    Inventors: Louise Edwards, Abdelmalik Slassi, Ashok Tehim, Tao Xin
  • Patent number: 7960422
    Abstract: Compounds of formula (I) wherein R1 is as well as pharmaceutically acceptable salts, hydrates and/or enantiomers thereof are useful as compounds that exhibit activity at metabotropic glutamate receptors.
    Type: Grant
    Filed: October 17, 2008
    Date of Patent: June 14, 2011
    Assignee: AstraZeneca AB
    Inventors: Erwan Arzel, Louise Edwards, Methvin Isaac, Donald A. McLeod, Abdelmalik Slassi, Tao Xin
  • Patent number: 7902401
    Abstract: Compounds of Formula I are useful in the treatment of epilepsy, neuropathic pain, acute and chronic inflammatory pain, migraine, tardive dyskinesia and other related CNS disorders. wherein: A and R1 to R8 are defined in the specification.
    Type: Grant
    Filed: December 14, 2006
    Date of Patent: March 8, 2011
    Assignee: NPS Pharmaceuticals, Inc.
    Inventors: Guy A. Higgins, Methvin Issac, Abdelmalik Slassi, Tao Xin
  • Patent number: 7772235
    Abstract: The present invention is directed to compounds of formula I: Wherein R1 to R5, X and Z are further defined in the description. The invention also relates to processes for the preparation of the compounds and to intermediates used in the preparation, pharmaceutical compositions containing the compounds, and to the use of the compounds in therapy.
    Type: Grant
    Filed: September 25, 2007
    Date of Patent: August 10, 2010
    Assignee: Astrazeneca AB
    Inventors: Methvin Isaac, Abdelmalik Slassi, Louise Edwards, Peter Dove, Tao Xin, Tomislav Stefanac
  • Patent number: 7691892
    Abstract: The present invention relates to new compounds of formula I, wherein P, Q, X1, X2, X3, X4, R1, R2, m and p, are as defined as in formula I, or, salts, solvates or solvated salts thereof, processes for their preparation and new intermediates used in the preparation thereof, pharmaceutical compositions containing said compounds and to the use of said compounds in therapy.
    Type: Grant
    Filed: February 18, 2005
    Date of Patent: April 6, 2010
    Assignee: AstraZeneca AB
    Inventors: Martin Johansson, Alexander Minidis, Karin Staaf, David Wensbo, Donald McLeod, Louise Edwards, Methvin Isaac, Anne O'Brien, Abdelmalik Slassi, Tao Xin, Tomislav Stefanac
  • Patent number: 7678796
    Abstract: The present invention is directed to novel compounds, to a process for their preparation, their use in therapy and pharmaceutical compositions comprising the novel compounds.
    Type: Grant
    Filed: April 25, 2007
    Date of Patent: March 16, 2010
    Assignee: AstraZeneca AB
    Inventors: Andreas Wallberg, Karolina Nilsson, Björn Holm, Mats Nagard, Kenneth Granberg, Abdelmalik Slassi, Louise Edwards, Methvin Isaac, Tao Xin, Tomislav Stefanac
  • Publication number: 20090312306
    Abstract: A compound of Formula I: and a method for treating a 5-HT2C receptor-mediated disorder in a mammal using the same.
    Type: Application
    Filed: July 20, 2007
    Publication date: December 17, 2009
    Inventors: Guangri Sun, Methvin Isaac, Tao Xin, Higgins Guy
  • Patent number: 7576077
    Abstract: The present invention is directed to compounds of formula I: wherein X1, X2, X3, X4, X5, X6, X7, X8, X9, X10, R1, R2, R3, R4, and n are as defined for formula I in the description. The invention also relates to processes for the preparation of the compounds and to new intermediates employed in the preparation, pharmaceutical compositions containing the compounds, and to the use of the compounds in therapy.
    Type: Grant
    Filed: February 18, 2005
    Date of Patent: August 18, 2009
    Assignee: Astrazeneca AB
    Inventors: David Wensbo, Martin Johansson, Alexander Minidis, Karin Staaf, Annika Kers, Louise Edwards, Methvin Isaac, Tom Stefanac, Abdelmalik Slassi, Don McLeod, Tao Xin
  • Publication number: 20090131454
    Abstract: The present invention is directed to novel compounds, their use in therapy and pharmaceutical compositions comprising said novel compounds.
    Type: Application
    Filed: October 17, 2008
    Publication date: May 21, 2009
    Applicant: AstraZeneca AB
    Inventors: Erwan Arzel, Louise Edwards, Methvin Isaac, Donald A. McLeod, Abdelmalik Slassi, Tao Xin