Abstract: A system comprises one or more processors. The system further comprises memory having computer readable instructions stored thereon that, when executed by the one or more processors, cause the system to: obtain a reference tree of nodes and linkages for a reference three dimensional volumetric representation of a branched anatomical formation in a reference state; based on the reference tree, generate a reference three dimensional geometric model; based on measurements from a sensor system, detect deformation of the branched anatomical formation; based on the detected deformation, obtain a deformed tree of nodes and linkages; and generate a three dimensional deformation field that represents the detected deformation of the branched anatomical formation.

Abstract: A system comprises a medical instrument including a sensing tool and comprises a processing unit including one or more processors. The processing unit is configured to receive data related to a patient anatomy from the sensing tool while the medical instrument traverses the patient anatomy. The processing unit is further configured to construct an anatomic model of the patient anatomy from the data received from the sensing tool. The processing unit is further configured to generate an image of the anatomic model for display and register a position of the medical instrument to the anatomic model.

Abstract: A method of planning a procedure to deploy an interventional instrument comprises receiving a model of an anatomic structure. The anatomic structure includes a plurality of passageways. The method further includes identifying a target structure in the model and receiving information about an operational capability of the interventional instrument within the plurality of passageways. The method further comprises identifying a planned deployment location for positioning a distal tip of the interventional instrument to perform the procedure on the target structure based upon the operational capability of the interventional instrument.

Abstract: A computer-assisted medical system comprises a fluoroscopic imager having a full scan range in a surgical coordinate space. The system further comprises one or more processors configured to perform a method. The method includes receiving a first fluoroscopic image data set of a patient anatomy. The first fluoroscopic image data set is obtained from the full scan range of the fluoroscopic imager. The method further includes receiving at least one additional fluoroscopic image data set of the patient anatomy from the fluoroscopic imager operating in a constrained range substantially smaller than the full scan range. The method further includes constructing a first planar tomographic image from the first and at least one additional fluoroscopic image data sets.

Abstract: A method of registering sets of anatomical data for use during a surgical procedure is provided herein. The method may include segmenting a set of first modality image data representing a model of one or more passageways within a patient and generating a first set of points based on the segmented set of first modality image data representing the model of the one or more passageway's. The method may further include determining a set of matches between a second set of points and the first set of points, wherein the second set of points is obtained by a second modality and discarding a subset of the set of matches based on a first heuristic to generate a modified set of matches. The second set of points may then be moved relative to the first set of points based on the modified set of matches and displayed on a display.

Abstract: A trans-inductor voltage regulator (TLVR) circuit has multiple phases and a regulator block for each phase. Each regulator block is connected to an output capacitor of the TLVR circuit by way of a first winding of a corresponding nonlinear transformer. A second winding of the nonlinear transformers are connected in series with a compensation inductor. The first winding of the corresponding nonlinear transformer has a first inductance when a load current is at a first level, and the first winding of the corresponding nonlinear transformer has a second inductance that is less than the first inductance when the load current is at a second level that is higher than the first level.

Abstract: A tool tracking method comprises receiving stereo image data of a tool. The tool includes a tracking marker. The method also comprises receiving first kinematic data for the tool and determining a three-dimensional image-derived pose of the tool from the stereo image data of the tool and the tracking marker. The method also comprises determining a first kinematic pose of the tool from the first kinematic data and determining a pose offset between the image-derived pose of the tool and the first kinematic pose of the tool. The method also comprises determining a corrected first kinematic pose of the tool based on the pose offset and the first kinematic data.

Abstract: An earpiece includes a housing, a sound transmission component, a sound reception component, a force application structure and a trigger. A cavity is formed in the housing. The sound transmission component is provided in the cavity. The sound reception component is provided on the housing, and can move along a predetermined path. At least a retracted position and a stretched position are arranged on the predetermined path. The force application structure is connected to the sound reception component, and configured to drive the sound reception component to move to the retracted position or the stretched position. The earpiece in the present disclosure stretches out or retracts the sound reception component automatically. The earpiece in the present disclosure does not need the user to stretch out or retract the sound reception component manually, with good user experience.

Abstract: A system may comprise an image capture device to capture an image of a work site. The system may also comprise a processor to determine whether a tool disposed at the work site is energized and determine a first area of the captured image of the work site, including or adjacent to an image of a portion of the tool in the captured image. The processor may also determine a second area of the captured image including a remainder of the captured image that does not include the first area. Conditioned upon determining that the tool is energized, at least one of the first area and the second area of the captured image of the work site may be processed to indicate that the tool in the first area is being energized. The image of the work site with the first area and the second area may be displayed.

Abstract: A trans-inductor voltage regulator (TLVR) circuit has multiple phases and a regulator block for each phase. Each regulator block has a winding of a transformer as an output inductor. The other windings of the transformers are connected in series with a nonlinear compensation inductor. The compensation inductor has a large inductance when the compensation inductor current is responsive to a steady state load current and has a small inductance when the compensation inductor current is responsive to a transient load current.

Abstract: A system comprises a medical instrument, including a sensing tool, and a processing unit configured to apply a segmentation function using a first seed to a three-dimensional image of a patient anatomy to create a model; receive position data from the instrument while navigating the patient anatomy; register a position of the instrument with the model; receive data related to the patient anatomy from the sensing tool; and update the model in response to detecting a difference between the model and the patient anatomy. Updating the model includes reapplying the segmentation function using a second seed corresponding to a passageway of the patient anatomy that is not present within the model. Detecting the difference between the model and the patient anatomy includes analyzing temporal information obtained from shape data generated by the sensing tool while the instrument traverses portions of the patient anatomy not represented by the model.

Abstract: A multi-rotor unmanned aerial vehicle (UAV) includes a central body including an outer surface and an inner surface, a plurality of branch members connected to the central body, each branch member configured to support a corresponding actuator assembly, one or more receiving structures positioned on the outer surface of the central body and configured to receive one or more electrical components, the one or more electrical components comprising at least a battery of the UAV, and an indicator light disposed at an opening or a window on one of the plurality of branch members, wherein the opening or the window is made of a transparent or semi-transparent material.

Abstract: An unmanned aerial vehicle includes a central body and a plurality of arms extendable from the central body. Each of the plurality of arms is configured to support one or more propulsion units. Each of the plurality of arms is configured to transform between (1) a flight configuration in which the arm is extending away from the central body and (2) a compact configuration in which the arm is folded against the central body. At least one of the plurality of arms is configured to rotate about a first rotational axis and at least a portion of the at least one of the plurality of arms is configured to rotate about a second rotational axis not parallel to the first rotational axis.

Abstract: A shared electronic device management method is implemented in a shared electronic device management device. The method includes receiving a function instruction, obtaining verification information, linking the obtained verification information to verification information in a database, determining whether the obtained verification information meets a first preset condition, implementing the function instruction if the obtained verification information meets the first preset condition, and outputting a prompt if the obtained verification information does not meet the first preset condition. The function instruction includes any one of retrieving, depositing, and repairing a shared electronic device. The verification information includes user verification information and shared electronic device verification information.

Abstract: A system for performing an interventional procedure comprises an interventional instrument and a control system.

Abstract: An apparatus includes a controller. To control current through a motor winding, the controller monitors a magnitude of current supplied through the motor winding. The controller compares the magnitude of current to a threshold value. In response to detecting that the magnitude of current crosses the threshold value, the controller terminates a flow of the current through the motor winding. In one application, termination of the current through the motor winding supports more efficient use of energy to drive the motor winding. For example, via the controller, terminating the current through the motor winding to prevent the current from flowing in a reverse direction through the motor winding.

Abstract: A system for inducing activity of immune cells, comprises a chimeric antigen receptor, a T cell receptor, and various combinations thereof.

Abstract: A system includes a catheter, a display system, and a control system in communication with the catheter and the display system. The control system includes one or more processors configured for receiving a set of model points of a model of one or more passageways of a patient and receiving a first set of measured points collected from within the patient passageways. Each point includes coordinates within a surgical environment occupied by the patient. The one or more processors are also configured for generating a first registration between the set of measured points and the set of model points, generating a second registration between a second set of measured points and the set of model points, and determining, after generating the first and second registrations, whether to implement the second registration in place of the first registration.

Abstract: An exemplary processing system accesses a three-dimensional (3D) model of an anatomical structure of a patient and applies a detection process to the 3D model to detect a single-layer anatomical feature in the anatomical structure. The detection process includes generating, from the 3D model, a probability map of candidate points for the single-layer anatomical feature, and generating, based on the probability map of candidate points, a single-layer mesh representing the single-layer anatomical feature.

Abstract: Provided herein are anti-DLL3 chimeric antigen receptors (CARs), DLL3 binding proteins and uses of such CARs or DLL3 binding proteins in the treatment of DLL3 associated disorders, such as small cell lung cancer.