Abstract: A system for image reconstruction in magnetic resonance imaging (MRI) is provided. The system may obtain undersampled k-space data associated with an object, wherein the undersampled K-space data may be generated based on magnetic resonance (MR) signals collected by an MR scanner that scans the object. The system may construct an ordinary differential equation (ODE) that formulates a reconstruction of an MR image based on the undersampled k-space data. The system may further generate the MR image of the object by solving the ODE based on the undersampled k-space data using an ODE solver.

Abstract: Described herein are neural network-based systems, methods and instrumentalities associated with estimating the motion of an anatomical structure. The motion estimation may be performed using a feature pyramid and/or a motion pyramid that correspond to multiple image scales. The motion estimation may be performed using neural networks and parameters that are learned via a training process involving a student network and a teacher network pre-pretrained with abilities to apply progressive motion compensation.

Abstract: Methods and systems for organizing medical data. For example, a computer-implemented method includes receiving first data of a first data category, the first data having a first data format; extracting a first plurality of attributes from the first data using a first extractor; mapping the first plurality of attributes to an unified data format using a first mapper; receiving second data of a second data category, the second data having a second data format; extracting a second plurality of attributes from the second data using a second extractor; mapping the second plurality of attributes to the unified data format using a second mapper; and building an ontology for a use case by at least linking the first plurality of attributes and the second plurality of attributes.

Abstract: A system for physiological motion measurement is provided. The system may acquire a reference image corresponding to a reference motion phase of an ROI and a target image of the ROI corresponding to a target motion phase, wherein the reference motion phase may be different from the target motion phase. The system may identify one or more feature points relating to the ROI from the reference image, and determine a motion field of the feature points from the reference motion phase to the target motion phase using a motion prediction model. An input of the motion prediction model may include at least the reference image and the target image. The system may further determine a physiological condition of the ROI based on the motion field.

Abstract: For patient weight estimation in a medical imaging system, a patient model, such as a mesh, is fit to a depth image. One or more feature values are extracted from the fit patient model, reducing the noise and clutter in the values. The weight estimation is regressed from the extracted features.

Abstract: Described herein are neural network-based systems, methods and instrumentalities associated with estimating the motion of an anatomical structure. The motion estimation may be performed utilizing pre-learned knowledge of the anatomy of the anatomical structure. The anatomical knowledge may be learned via a variational autoencoder, which may then be used to optimize the parameters of a motion estimation neural network system such that, when performing motion estimation for the anatomical structure, the motion estimation neural network system may produce results that conform with the underlying anatomy of anatomical structure.

Abstract: An apparatus is configured to receive input image data corresponding to output image data of a first radiology scanner device, translate the input image data into a format corresponding to output image data of a second radiology scanner device and generate an output image corresponding to the translated input image data on a post processing imaging device associated with the first radiology scanner device. Medical images from a new scanner can be translate to look as if they came from a scanner of another vendor.

Abstract: An automated process for data annotation of medical images includes obtaining image data from an imaging sensor, partitioning the image data, identifying an object of interest in the partitioned image data, generating an initial contour with one or more control points with respect to the object of interest, identifying a manual adjustment of one of the control points, automatically adjust a position of at least one other control point within a predetermined range of the manually adjusted control point to a new position, the new position of the at least one other control point and manually adjusted control point defining a new contour, and generating an updated image with the new contour and corresponding control points.

Abstract: Described herein are systems, methods, and instrumentalities associated with denoising medical images such as fluoroscopic images using deep learning techniques. A first artificial neural network (ANN) is trained to denoise an input medical image in accordance with a provided target noise level. The training of the first ANN is conducted by pairing a noisy input image with target denoised images that include different levels of noise. These target denoised images are generated using a second ANN as intermediate outputs of the second ANN during different training iterations. As such, the first ANN may learn to perform the denoising task in an unsupervised manner without requiring noise-free training images as the ground truth.

Abstract: Described herein are systems, methods, and instrumentalities associated with image segmentation such as tubular structure segmentation. An artificial neural network is trained to segment tubular structures of interest in a medical scan image based on annotated images of a different type of tubular structures that may have a different contrast and/or appearance from the tubular structures of interest. The training may be conducted in multiple stages during which a segmentation model learned from the annotated images during a first stage may be modified to fit the tubular structures of interest in a second stage. In examples, the tubular structures of interest may include coronary arteries, catheters, guide wires, etc., and the annotated images used for training the artificial neural network may include blood vessels such as retina blood vessels.

Abstract: Described herein are systems, methods, and instrumentalities associated with landmark detection. The detection may be accomplished by determining a graph representation of a plurality of hypothetical landmarks detected in one or more medical images. The graph representation may include nodes that represent the hypothetical landmarks and edges that represent the relationships between paired hypothetical landmarks. The graph representation may be processed using a graph neural network such a message passing graph neural network, by which the landmark detection problem may be converted and solved as a graph node labeling problem.

Abstract: Described herein are systems, methods, and instrumentalities associated with generating multi-contrast MRI images associated with an MRI study. The systems, methods, and instrumentalities utilize an artificial neural network (ANN) trained to jointly determine MRI data sampling patterns for the multiple contrasts based on predetermined quality criteria associated with the MRI study and reconstruct MRI images with the multiple contrasts based on under-sampled MRI data acquired using the sampling patterns. The training of the ANN may be conducted with an objective to improve the quality of the whole MRI study rather than individual contrasts. As such, the ANN may learn to allocate resources among the multiple contrasts in a manner that optimizes the performance of the whole MRI study.

Abstract: Described herein are systems, methods and instrumentalities associated with automatic assessment of aneurysms. An automatic aneurysm assessment system or apparatus may be configured to obtain, e.g., using a pre-trained artificial neural network, strain values associated one or more locations of a human heart and one or more cardiac phases of the human heart and derive a representation (e.g., a 2D matrix) of the strain values across time and/or space. The system or apparatus may determine, based on the derived representation of the strain values, respective strain patterns associated with the one or more locations of the human heart and further determine whether the one or more locations are aneurysm locations by comparing the automatically determined strain patterns with predetermined normal strain patterns of the heart and determining the presence or risk of aneurysms based on the comparison.

Abstract: Described herein are systems, methods, and instrumentalities associated with segmenting and/or determining the shape of an anatomical structure. An artificial neural network (ANN) is used to perform these tasks based on a statistical shape model of the anatomical structure. The ANN is trained by evaluating and backpropagating multiple losses associated with shape estimation and segmentation mask generation. The model obtained using these techniques may be used for different clinical purposes including, for example, motion estimation and motion tracking.

Abstract: Described herein are neural network-based systems, methods and instrumentalities associated with cardiac assessment. An apparatus as described herein may obtain electrocardiographic imaging (ECGI) information associated with a human heart and magnetic resonance imaging (MRI) information associated with the human heart, and integrate the ECGI and MRI information using a machine-learned model. Using the integrated ECGI and MRI information, the apparatus may predict target ablation sites, estimate electrophysiology (EP) measurements, and/or simulate the electrical system of the human heart.

Abstract: In Multiplex MRI image reconstruction, a hardware processor acquires sub-sampled Multiplex MRI data and reconstructs parametric images from the sub-sampled Multiplex MRI data. A machine learning model or deep learning model uses the subsampled Multiplex MRI data as the input and parametric maps calculated from the fully sampled data, or reconstructed fully sample data, as the ground truth. The model learns to reconstruct the parametric maps directly from the subsampled Multiplex MRI data.

Abstract: A neural network-based method for quantifying a volume of a specimen. The method includes providing a specimen, capturing images of the specimen, and directly classifying to one of a plurality of volume classes or volumes using a trained neural network. Quality check modules and specimen testing apparatus adapted to carry out the volume quantification method are described, as are other aspects.

Abstract: Automatically generating an explanation for a decision prediction from a machine learning algorithm includes using a first processor of a computing device to run the machine learning algorithm using one or more input data; generating a decision prediction output based on the one or more input data; using a second processor to access the decision prediction output of the first processor; generating additional information that identifies one or more causal relationships between the prediction of the first algorithm and the one or more input data; and providing the additional information as the explanation in a user-understandable format on a display of the computing device.

Abstract: A model-based method for quantifying a specimen. The method includes providing a specimen, capturing images of the specimen while illuminated by multiple spectra at different nominal wavelengths, and exposures, and classifying the specimen into various class types comprising one or more of serum or plasma portion, settled blood portion, gel separator (if used), air, tube, label, or cap; and quantifying of the specimen. Quantifying includes determining one or more of: a location of a liquid-air interface, a location of a serum-blood interface, a location of a serum-gel interface, a location of a blood-gel interface, a volume and/or a depth of the serum or plasma portion, or a volume and/or a depth of the settled blood portion. Quality check modules and specimen testing apparatus adapted to carry out the method are described, as are other aspects.

Abstract: Disclosed herein are systems, methods, and instrumentalities associated with reconstructing magnetic resonance (MR) images based on multi-slice, under-sampled MRI data (e.g., k-space data). The multi-slice MRI data may be acquired using a simultaneous multi-slice (SMS) technique and MRI information associated with multiple MRI slices may be entangled in the multi-slice MRI data. A neural network may be trained and used to disentangle the MRI information and reconstruct MRI images for the different slices. A data consistency component may be used to estimate k-space data based on estimates made by the neural network, from which respective MRI images associated with multiple MRI slices may be obtained by applying a Fourier transform to the k-space data.