Abstract: A treatment device is disclosed for treating an area within a biological pathway or space. The treatment device includes a catheter that has a first pair of dilation balloons and a second pair of dilation balloons configured to create a sealed treatment area within a vessel. Treatment fluids may be provided to the treatment area via a fluid lumen and fluid may be removed from the treatment area via the same fluid lumen or separate aspiration lumen.

Abstract: A biopsy device having a cutting element is disclosed. The cutting element includes an inner cannula having a tissue receiving aperture disposed proximate a distal end thereof and an inner lumen. The inner cannula is slidably disposed within the inner lumen of an outer cannula. A vacuum chamber is disposed about at least a portion of the cutting element and is configured to create a vacuum in the cutting element during a biopsy procedure. The inner cannula is advanced distally outwardly and to cause the vacuum to be generated in the vacuum chamber. The vacuum is delivered to the cutting element whereby tissue is drawn into the tissue receiving aperture. The outer cannula is advanced distally outwardly after the inner cannula such that tissue drawn into the tissue cutting aperture is severed.

Abstract: A treatment device is disclosed for treating an area within a biological pathway or space. The treatment device includes a catheter that has a first pair of dilation balloons and a second pair of dilation balloons configured to create a sealed treatment area within a vessel. Treatment fluids may be provided to the treatment area via a fluid lumen and fluid may be removed from the treatment area via the same fluid lumen or separate aspiration lumen.

Abstract: A biopsy device having a cutting element is disclosed. The cutting element includes an inner cannula having a tissue receiving aperture disposed proximate a distal end thereof and an inner lumen. The inner cannula is slidably disposed within the inner lumen of an outer cannula. A vacuum chamber is disposed about at least a portion of the cutting element and is configured to create a vacuum in the cutting element during a biopsy procedure. The inner cannula is advanced distally outwardly and to cause the vacuum to be generated in the vacuum chamber. The vacuum is delivered to the cutting element whereby tissue is drawn into the tissue receiving aperture. The outer cannula is advanced distally outwardly after the inner cannula such that tissue drawn into the tissue cutting aperture is severed.

Abstract: An biopsy apparatus includes a pressure and vacuum generator including a first cylinder and a first piston movably disposed within the cylinder. The cylinder has a pressure generating region and a vacuum generating region. The biopsy apparatus also includes an outer cannula and an inner cannula having a lumen. The inner cannula is movably disposed within the outer cannula, and the vacuum generating region is in one-way fluid communication with the inner cannula lumen.

Abstract: An adapter is provided for use with a biopsy device that includes a cutting element having an outer cannula hub removably mounted to a handpiece. The cutting element includes an outer cannula connected to the outer cannula hub and an inner cannula disposed within the outer cannula and attached to the handpiece. The outer cannula hub allows removal of the handpiece and inner cannula from the outer cannula. The adapter includes a base, a cradle moveably mounted to the base and configured to rotatably support the biopsy device therein, and an indexing guide moveable with the cradle having a receptacle within which the outer cannula hub is rotatably received. The cradle and indexing guide are configured to inhibit rotation and axial movement of the biopsy device relative to the cradle, and facilitates removal of the handpiece and inner cannula from the outer cannula, while maintaining registration with the biopsy site.

Abstract: A tissue sample collection device and method are described and disclosed. The tissue sample collection device has a filter that is removably disposed within a sleeve. The filter has an open proximal end and an internal passageway that is in fluid communication with the open proximal end for the passage of fluids. The filter is substantially impermeable to tissue samples but allows the passage of fluids into the internal passageway at a plurality of spaced apart locations along at least a portion of the filter's length. When used to collect tissue samples, the samples are collected on the exterior surface of the filter. Thus, the filter can be removed from the sleeve, and samples can be removed from the exterior surface of the filter.

Abstract: A medical targeting and device introduction system includes an introducer having a cannula, and a hub. The cannula is defined, at least in part, by an inner lumen. The hub includes a latch to releasably secure the hub to a biopsy device. The hub includes a proximal end and a distal end. The latch extends from the proximal end, and the hemostatic valve is interposed within the introducer.

Abstract: A selectively lockable introducer assembly is disclosed that comprises an introducer cannula and a needle guide. The introducer cannula is defined by a proximal end and a distal end and includes a lumen extending therebetween. The needle guide is defined by a body portion that includes at least one channel extending therethrough. The introducer cannula is configured to be selectively receivable within the at least one channel and the introducer cannula may be selectively lockable with respect to the needle guide such that the introducer cannula is selectively prevented from moving laterally with respect to the needle guide.

Abstract: A medical targeting and device introduction system includes an introducer having a cannula, and a hub. The cannula is defined, at least in part, by an inner lumen. The hub includes a latch to releasably secure the hub to a biopsy device. The hub includes a proximal end and a distal end. The latch extends from the proximal end, and the hemostatic valve is interposed within the introducer.

Abstract: A biopsy marker deployment device adapted to selectively deposit a marker in a target location, such as a biopsy site. In one embodiment, the device includes a deployment assembly comprising a cannula adapted to house at least one marker, an outlet aperture defined by a portion of the cannula, and an actuatable pushrod slidably disposed and movable within the cannula. The deployment assembly further comprises a selectively opening outlet door movable between an open position and a closed position. The outlet door is biased in the closed position and at least partially obstructs the aperture in the closed position to prevent a marker from reentering the cannula upon deployment.

Abstract: A biopsy device is disclosed that comprises a cutting element mounted to a handpiece and a vacuum chamber. The cutting element comprises a stylet assembly and an outer cannula assembly. The stylet assembly includes a stylet that includes an open proximal end and a tissue opening at a distal end thereof. The tissue receiving opening is in communication with a lumen extending through the stylet. The outer cannula assembly includes an outer cannula that is slidably mounted over the stylet and has an open distal end with a cutting edge formed thereon. The vacuum chamber is in communication with the lumen of the stylet. The stylet is selectively advanced distally outwardly with respect to outer cannula to expose the tissue opening to targeted tissue. The outer cannula is selectively advanced over the tissue opening to sever tissue, while vacuum is generated in the vacuum chamber and delivered to the tissue opening through the lumen.

Abstract: A fluid control element having a flexible member that is adapted for selective deformation when an element inserted therein. The flexible member includes at least one incision or opening that defines at least one cusp that selectively opens when the element is inserted therein. The incision or opening is biased into a normally and substantially closed position such that fluids are substantially prevented from flowing through the fluid control element.

Abstract: A biopsy marker deployment device adapted to selectively deposit a marker in a target location, such as a biopsy site. In one embodiment, the device includes a deployment assembly comprising a cannula adapted to house at least one marker, an outlet aperture defined by a portion of the cannula, and an actuatable pushrod slidably disposed and movable within the cannula. The deployment assembly further comprises a selectively opening outlet door movable between an open position and a closed position. The outlet door is biased in the closed position and at least partially obstructs the aperture in the closed position to prevent a marker from reentering the cannula upon deployment.

Abstract: A tissue collection tray is described for use with a biopsy device. The tissue collection tray includes a well portion, a body portion and a divider. The well portion is defined by first and second ends, a bottom and at least two walls. The body portion includes a recess formed therein. The divider includes a groove formed therein. The divider is positioned between the recess and the well portion.

Abstract: A biopsy marker deployment device is provided herein. According to one exemplary embodiment, the deployment device includes a deployment assembly and an actuator configured to selectively actuate the deployment assembly. The deployment assembly is configured to selectively deposit a marker in a biopsy site through at least one aperture and to substantially reduce space between the aperture and the deployment assembly.

Abstract: A site marker deployment device is disclosed. The site marker deployment device comprises an inner member and a deployment cannula. The inner member has a distal end. The deployment cannula has an open distal end. The deployment cannula is slidably disposed over the inner member and a site marker that is disposed within the deployment cannula adjacent the inner member at the distal end of the depolyment cannula. The inner member is configured to be held generally stationary relative to a target location as deployment cannula is selectively moved between a pre-deployment configuration wherein the deployment cannula is positioned over at least a portion of the site marker and a deployed configuration wherein the deployment cannula is retracted such that the site marker is released from the deployment cannula.

Abstract: An adapter is provided for use with a biopsy device that includes a cutting element having an outer cannula hub removably mounted to a handpiece. The cutting element includes an outer cannula connected to the outer cannula hub and an inner cannula disposed within the outer cannula and attached to the handpiece. The outer cannula hub allows removal of the handpiece and inner cannula from the outer cannula. The adapter includes a base, a cradle moveably mounted to the base and configured to rotatably support the biopsy device therein, and an indexing guide moveable with the cradle having a receptacle within which the outer cannula hub is rotatably received. The cradle and indexing guide are configured to inhibit rotation and axial movement of the biopsy device relative to the cradle, and facilitates removal of the handpiece and inner cannula from the outer cannula, while maintaining registration with the biopsy site.

Abstract: An biopsy apparatus includes a pressure and vacuum generator including a first cylinder and a first piston movably disposed within the cylinder. The cylinder has a pressure generating region and a vacuum generating region. The biopsy apparatus also includes an outer cannula and an inner cannula having a lumen. The inner cannula is movably disposed within the outer cannula, and the vacuum generating region is in one-way fluid communication with the inner cannula lumen.

Abstract: Method, system, and article of manufacture for assembling a compound document according to a collection of domain-specific rules. For example, a content management system (CMS) may be configured to process the domain-specific compound document according to domain-specific schema and rules (e.g., an XML schema and DTD), while at the same time, maintaining the compound document in a generic form according to a generic schema for a compound document format used by the CMS.