Patents by Inventor Terumi Tamura
Terumi Tamura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240044798Abstract: Embodied is a flow cell that is for analysis of nucleic acid and that is capable of inhibiting complication of data processing without a reduction in throughput. The flow cell for analysis of nucleic acid comprises: a flow path formation body that has a flow path into which a nucleic acid sample flows; and a flow path formation body support member that has a region in which nucleic acid in a nucleic acid sample flowing into the flow path is to be adsorbed. The flow path formation body support member has the nucleic acid adsorption region in which nucleic acid is to be adsorbed, and a fluorescent particle adsorption region which is separated from the nucleic acid adsorption region, and in which fluorescent particles are to be adsorbed. In the fluorescent particle adsorption region, a blocking substance that can be specifically adsorbed to the fluorescent particle adsorption region is adsorbed.Type: ApplicationFiled: December 21, 2020Publication date: February 8, 2024Inventors: Noriko EBINE, Terumi TAMURA, Masatoshi NARAHARA
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Patent number: 11209197Abstract: The present invention provides a refrigerating/heating device that efficiently refrigerates and heats while suppressing device costs. This refrigerating/heating device for efficiently heating and refrigerating is provided with: a refrigeration chamber; a Peltier-type cooler for supplying cold air to inside the refrigeration chamber; a heat radiation member for radiating Peltier heat; fans for air-cooling the heat radiation member; an exhaust duct through which waste heat from the fans and the heat radiation member passes; and an installation part to which a subject to be heated can be installed. The subject to be heated is installed in the waste heat flow path of the exhaust duct and heated.Type: GrantFiled: June 28, 2016Date of Patent: December 28, 2021Assignee: Hitachi High-Tech CorporationInventors: Tadao Yabuhara, Terumi Tamura, Hiroshi Watanabe
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Publication number: 20210208172Abstract: The purpose of the present invention is to enhance the throughput of an analysis device by efficiently delivering sample containers between an accommodation unit and measurement unit. This analysis device comprises a first holding part for holding a sample container to be delivered to a measurement unit and a second holding part for holding a sample container received from the measurement unit. The first holding part and second holding part are moved in an integrated manner (see FIG. 1B).Type: ApplicationFiled: May 22, 2018Publication date: July 8, 2021Applicant: Hitachi High-Tech CorporationInventors: Tadao Yabuhara, Akira Masuya, Terumi Tamura
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Patent number: 10815524Abstract: The purpose of the invention is to provide a nucleic acid analyzer that sets and executes temperature regulation, said temperature regulation matching the characteristics of analyzing items and the configuration of the analyzer, by a simple operation while preventing deterioration in analytical performance caused by partial overheating of a liquid reaction mixture to thereby improve temperature change speed and shorten analysis time. To achieve the above purpose, provided is a method wherein, in the case of performing overshooting: as a first processing, the temperature is continuously elevated until reaching a target overshoot temperature; as a second processing, after reaching the aforesaid temperature, the overshoot target temperature is maintained for a preset period of time; and, as a third processing, the temperature is continuously lowered until reaching a target temperature of the liquid reaction mixture.Type: GrantFiled: February 23, 2015Date of Patent: October 27, 2020Assignee: Hitachi High-Tech CorporationInventors: Manami Nammoku, Terumi Tamura, Kohshi Maeda, Daisuke Morishima, Toshinari Sakurai, Wataru Sato
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Patent number: 10781440Abstract: An automatic analyzer including a function for operating control materials and its operation method are provided. The analyzer is configured to start sampling by giving priority to an entirety of control materials corresponding to all assay items required for measurement. The analyzer is also configured to automatically start sampling of a patient specimen based on a preliminarily set sampling timing after completion of sampling of the entirety of control materials. The analyzer is also configured to stop, when an abnormality is present in a measurement result of at least any one of control materials in the group of control materials, sampling of a patient specimen corresponding to a control material in which the abnormality is found, and notify a tester of the abnormality.Type: GrantFiled: February 23, 2015Date of Patent: September 22, 2020Assignee: Hitachi High-Tech CorporationInventors: Kohshi Maeda, Terumi Tamura, Daisuke Morishima
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Publication number: 20200182518Abstract: The present invention provides a refrigerating/heating device that efficiently refrigerates and heats while suppressing device costs. This refrigerating/heating device for efficiently heating and refrigerating is provided with: a refrigeration chamber; a Peltier-type cooler for supplying cold air to inside the refrigeration chamber; a heat radiation member for radiating Peltier heat; fans for air-cooling the heat radiation member; an exhaust duct through which waste heat from the fans and the heat radiation member passes; and an installation part to which a subject to be heated can be installed. The subject to be heated is installed in the waste heat flow path of the exhaust duct and heated.Type: ApplicationFiled: June 28, 2016Publication date: June 11, 2020Inventors: Tadao YABUHARA, Terumi TAMURA, Hiroshi WATANABE
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Patent number: 10302641Abstract: An analyzing device of the present invention is provided with a flow chamber that a fluid including magnetic particles associated with a labeling substance flows from a fluid inlet to a fluid outlet, magnetic trap means to apply a magnetic field for trapping the magnetic particles to the fluid in the flow chamber, a working electrode and a counter electrode to apply a voltage to the magnetic particles trapped by the magnetic trap means, and to emit a luminescence, a light detection element to detect a luminescence derived from the labeling substance on the magnetic particles trapped in the flow chamber, and regulating means to regulate a region that the light detection element detects the luminescence derived from the labeling substance on a part of magnetic particles of them trapped by the magnetic trap means.Type: GrantFiled: January 23, 2014Date of Patent: May 28, 2019Assignee: Roche Diagnostics Operations, Inc.Inventors: Shunichiro Nobuki, Muneo Maeshima, Terumi Tamura, Kenta Imai
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Patent number: 10018644Abstract: A cartridge for dispensing a fluid is presented. The cartridge comprises a reservoir chamber for receiving the fluid. The reservoir chamber has a fluid outlet. The cartridge further comprises a controllable dispenser component for dispensing a dispensing volume of the fluid from the reservoir chamber. The dispenser component is connected to the fluid outlet of the reservoir. The cartridge further comprises a single compressible fluid pump with a single elastic pumping element and a conduit extending from the fluid pump towards the fluid outlet. The fluid pump discharges a mixing volume of the fluid from the conduit into the reservoir chamber upon compression of the elastic pumping element. The mixing volume depends on the degree of compression of the elastic pumping element. The fluid pump sucks in the mixing volume from the reservoir into the conduit upon decompression of the elastic pumping element.Type: GrantFiled: January 26, 2016Date of Patent: July 10, 2018Assignees: Roche Diagnostics Operations, Inc., Hitachi High-Technologies CorporationInventors: Thorsten Brueckner, Christoph Boehm, Juergen Spinke, Terumi Tamura, Taku Sakazume, Kyoko Imai
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Publication number: 20180037930Abstract: The purpose of the invention is to provide a nucleic acid analyzer that sets and executes temperature regulation, said temperature regulation matching the characteristics of analyzing items and the configuration of the analyzer, by a simple operation while preventing deterioration in analytical performance caused by partial overheating of a liquid reaction mixture to thereby improve temperature change speed and shorten analysis time. To achieve the above purpose, provided is a method wherein, in the case of performing overshooting: as a first processing, the temperature is continuously elevated until reaching a target overshoot temperature; as a second processing, after reaching the aforesaid temperature, the overshoot target temperature is maintained for a preset period of time; and, as a third processing, the temperature is continuously lowered until reaching a target temperature of the liquid reaction mixture.Type: ApplicationFiled: February 23, 2015Publication date: February 8, 2018Inventors: Manami NAMMOKU, Terumi TAMURA, Kohshi MAEDA, Daisuke MORISHIMA, Toshinari SAKURAI, Wataru SATO
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Publication number: 20180030433Abstract: Operation methods for control material conventionally differ in each inspection laboratory, and automatic operation according to laboratory operation standards has been difficult. Further, since operation for control material is complex and devices are operated on the basis of judgments by inspectors in accordance with results of measurement for control materials, highly-trained inspectors have been necessary. The present invention comprises multiple settings for automatically operating a control material in an automated analyzer, and executes an optimal setting according to the test laboratory and inspection items, and also executes an operation process for control material. If there is a possibility of a problem in an inspection process, the control material is automatically re-measured so that wasteful inspection can be prevented and the inspection can be automatically continued.Type: ApplicationFiled: February 23, 2015Publication date: February 1, 2018Inventors: Kohshi MAEDA, Terumi TAMURA, Daisuke MORISHIMA
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Patent number: 9395298Abstract: A blood coagulation analyzer that realizes both securement of a wide dynamic range and enhancement of sensitivity in blood coagulation analysis by selecting an appropriate angle of detection depending on the intensity of scattered light from each specimen without causing complexity of the analyzer. The analyzer has a reaction container. A storage unit is provided which takes in and stores multiple pieces of chronological light intensity variation data acquired from detectors arranged around a reaction container. A judgment unit selects light intensity variation data to be used for calculation of a blood coagulation time from the multiple pieces of light intensity variation data stored in the storage unit based on the amount of light intensity variation. A calculation unit calculates the blood coagulation time from the light intensity variation data selected by the judgment unit.Type: GrantFiled: November 19, 2010Date of Patent: July 19, 2016Assignee: Hitachi High-Technologies CorporationInventors: Akihisa Makino, Tomonori Mimura, Terumi Tamura, Sakuichiro Adachi
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Publication number: 20160139164Abstract: A cartridge for dispensing a fluid is presented. The cartridge comprises a reservoir chamber for receiving the fluid. The reservoir chamber has a fluid outlet. The cartridge further comprises a controllable dispenser component for dispensing a dispensing volume of the fluid from the reservoir chamber. The dispenser component is connected to the fluid outlet of the reservoir. The cartridge further comprises a single compressible fluid pump with a single elastic pumping element and a conduit extending from the fluid pump towards the fluid outlet. The fluid pump discharges a mixing volume of the fluid from the conduit into the reservoir chamber upon compression of the elastic pumping element. The mixing volume depends on the degree of compression of the elastic pumping element. The fluid pump sucks in the mixing volume from the reservoir into the conduit upon decompression of the elastic pumping element.Type: ApplicationFiled: January 26, 2016Publication date: May 19, 2016Inventors: Thorsten Brueckner, Christoph Boehm, Juergen Spinke, Terumi Tamura, Taku Sakazume, Kyoko Imai
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Publication number: 20160061831Abstract: An analyzing device of the present invention is provided with a flow chamber that a fluid including magnetic particles associated with a labeling substance flows from a fluid inlet to a fluid outlet, magnetic trap means to apply a magnetic field for trapping the magnetic particles to the fluid in the flow chamber, a working electrode and a counter electrode to apply a voltage to the magnetic particles trapped by the magnetic trap means, and to emit a luminescence, a light detection element to detect a luminescence derived from the labeling substance on the magnetic particles trapped in the flow chamber, and regulating means to regulate a region that the light detection element detects the luminescence derived from the labeling substance on a part of magnetic particles of them trapped by the magnetic trap means.Type: ApplicationFiled: January 23, 2014Publication date: March 3, 2016Applicant: Roche Diagnostics Operations, Inc.Inventors: Shunichiro Nobuki, Muneo Maeshima, Terumi Tamura, Kenta Imai
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Patent number: 8952324Abstract: The mass analyzing apparatus of the present invention can achieve the speed-up and simplification of the formation of a calibration curve for quantifying an analysis object in a mass analyzing apparatus.Type: GrantFiled: December 27, 2011Date of Patent: February 10, 2015Assignee: Hitachi High-Technologies CorporationInventors: Midori Sasaki, Terumi Tamura, Shinya Ito, Makoto Nogami
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Patent number: 8858882Abstract: There is provided a data processing method that reduces influences of air bubbles and dirt while maintaining changes in light amounts. Two scattering light photoreceivers are disposed in the forward direction. A photoreceiver 33a closer to the optical axis is taken to be a main angle photoreceiver, and a photoreceiver 33b further from the optical axis is taken to be a sub-angle photoreceiver. Noise is estimated based on the reaction process data of the sub-angle photoreceiver, and noise is reduced by subtracting the estimated noise from the reaction process data of the main angle photoreceiver.Type: GrantFiled: February 24, 2011Date of Patent: October 14, 2014Assignee: Hitachi High-Technologies CorporationInventors: Sakuichiro Adachi, Terumi Tamura, Hajime Yamazaki, Akihisa Makino, Takeshi Yogi
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Publication number: 20130277542Abstract: The mass analyzing apparatus of the present invention can achieve the speed-up and simplification of the formation of a calibration curve for quantifying an analysis object in a mass analyzing apparatus.Type: ApplicationFiled: December 27, 2011Publication date: October 24, 2013Inventors: Midori Sasaki, Terumi Tamura, Shinya Ito, Makoto Nogami
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Publication number: 20130048853Abstract: An adsorbent that enables solid phase extraction with high efficiency and good selectivity of solutes having a broad chromatographic polarity range including high-polarity solute molecules while suppressing adsorption of impurities, and a solid phase extraction method therefor are provided. A heterocyclic-ring-containing copolymer adsorbent that is provided herein comprises a copolymer that comprises: a multifunctional heterocyclic-ring-containing monomer having a heterocyclic ring containing at least two heteroatoms in the ring system; and a monomer that is copolymerizable with the multifunctional heterocyclic-ring-containing monomer, wherein the multifunctional heterocyclic ring constitutes the main chain structure.Type: ApplicationFiled: April 28, 2011Publication date: February 28, 2013Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATIONInventors: Jun Nunoshige, Hiroyuki Kagawa, Shinya Ito, Katsuhiro Kanda, Izumi Waki, Kotaro Araya, Terumi Tamura
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Publication number: 20120315190Abstract: There is provided a data processing method that reduces influences of air bubbles and dirt while maintaining changes in light amounts. Two scattering light photoreceivers are disposed in the forward direction. A photoreceiver 33a closer to the optical axis is taken to be a main angle photoreceiver, and a photoreceiver 33b further from the optical axis is taken to be a sub-angle photoreceiver. Noise is estimated based on the reaction process data of the sub-angle photoreceiver, and noise is reduced by subtracting the estimated noise from the reaction process data of the main angle photoreceiver.Type: ApplicationFiled: February 24, 2011Publication date: December 13, 2012Inventors: Sakuichiro Adachi, Terumi Tamura, Hajime Yamazaki, Akihisa Makino, Takeshi Yogi
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Publication number: 20120282139Abstract: A blood coagulation analyzer that realizes both securement of a wide dynamic range and enhancement of sensitivity in blood coagulation analysis by selecting an appropriate angle of detection depending on the intensity of scattered light from each specimen without causing complexity of the analyzer. The analyzer has a reaction container. A storage unit is provided which takes in and stores multiple pieces of chronological light intensity variation data acquired from detectors arranged around a reaction container. A judgment unit selects light intensity variation data to be used for calculation of a blood coagulation time from the multiple pieces of light intensity variation data stored in the storage unit based on the amount of light intensity variation. A calculation unit calculates the blood coagulation time from the light intensity variation data selected by the judgment unit.Type: ApplicationFiled: November 19, 2010Publication date: November 8, 2012Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATIONInventors: Akihisa Makino, Tomonori Mimura, Terumi Tamura, Sakuichiro Adachi
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Patent number: D687563Type: GrantFiled: September 12, 2012Date of Patent: August 6, 2013Assignee: Hitachi High-Technologies CorporationInventor: Terumi Tamura