Patents by Inventor Tetsuo Nishikawa
Tetsuo Nishikawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20200024388Abstract: A polyester resin composition includes a copolymer of a polycarboxylic acid component and a polyol component. The polycarboxylic acid component includes terephthalic acid and/or a derivative thereof The polyol component includes ethylene glycol and/or a derivative thereof and 2,2-dimethyl-1,3-propanediol and/or a derivative thereof. A content by percentage of 2,2-dimethyl-1,3-propanediol and/or the derivative thereof is 27 mol % to 55 mol % based on the total amount of the polyol component. The composition has an intrinsic viscosity of 0.5 dl/g to 0.6 dl/g.Type: ApplicationFiled: August 22, 2017Publication date: January 23, 2020Inventors: Yusuke ITO, Tomomitsu UENO, Hideaki TOMURA, Masahiro YAMA, Tetsuo NISHIKAWA, Toshio HONMA
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Patent number: 8110662Abstract: A cDNA fragment participating in the maintenance of smooth muscle differentiation was isolated using a culture system of chicken gizzard smooth muscle cells, the differential display method and the subtracted hybridization method. Using the obtained cDNA sequence as a query, cDNA sequences of Helix Research Institute (Japanese Patent Application No. 2000-118776) were retrieved, and thus, a novel gene “C-NT2RP3001495” was obtained. The protein encoded by this gene has two WW domains that participate in protein interactions in the N-terminal domain. Evidence suggests that this protein binds to other proteins, and thus regulates the intracellular signal transduction, gene expression, and so on, thereby participating in the maintenance of the differentiation of smooth muscle cells. This protein and compounds regulating the expression thereof are markedly useful in developing drugs for various diseases associated with abnormality in the maintenance of smooth muscle cell differentiation.Type: GrantFiled: October 9, 2007Date of Patent: February 7, 2012Assignees: Chugai Seiyaku Kabushiki KaishaInventors: Toshio Ota, Takao Isogai, Tetsuo Nishikawa, Koji Hayashi, Kaoru Otsuka, Jun-Ichi Yamamoto, Shizuko Ishii, Tomoyasu Sugiyama, Ai Wakamatsu, Keiichi Nagai, Tetsuji Otsuki, Shin-Ichi Funahashi, Shoji Miyata, Kenji Sobue, Kenichiro Hayashi
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Patent number: 7668344Abstract: (A) Luminance data is prepared. (B) A group of first order differential values is obtained from luminance values of said luminance data along a first direction, a group of second order differential values is obtained from the group of first order differential values, and first data is output in accordance with the group of second order differential values. There is provided a stain inspection method having high inspection correctness.Type: GrantFiled: February 9, 2006Date of Patent: February 23, 2010Assignee: Fujifilm CorporationInventors: Ichiro Matsumoto, Tetsuo Nishikawa
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Patent number: 7354968Abstract: The present invention provides a thermoplastic resin composition having a high specific gravity, flexibility and excellent processability that can be used as a material for forming various articles requiring both massiveness and flexibility. This thermoplastic resin composition contains 2.5 to 15 wt % of a styrene-based thermoplastic elastomer and 85 to 97.5 wt % of tungsten powder, and an molded article is obtained by melting and kneading this thermoplastic resin composition. This article can be used preferably as a balance weight attached to a wheel of an automobile, sports goods or the like.Type: GrantFiled: October 9, 2001Date of Patent: April 8, 2008Assignee: Sumitomo Rubber Industries, Ltd.Inventors: Tetsuo Nishikawa, Kazuo Haruta, Toshiaki Sakaki, Tetsuo Mizoguchi
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Publication number: 20080069826Abstract: A cDNA fragment participating in the maintenance of smooth muscle differentiation was isolated using a culture system of chicken gizzard smooth muscle cells, the differential display method and the subtracted hybridization method. Using the obtained cDNA sequence as a query, cDNA sequences of Helix Research Institute (Japanese Patent Application No. 2000-118776) were retrieved, and thus, a novel gene “C-NT2RP3001495” was obtained. The protein encoded by this gene has two WW domains that participate in protein interactions in the N-terminal domain. Evidence suggests that this protein binds to other proteins, and thus regulates the intracellular signal transduction, gene expression, and so on, thereby participating in the maintenance of the differentiation of smooth muscle cells. This protein and compounds regulating the expression thereof are markedly useful in developing drugs for various diseases associated with abnormality in the maintenance of smooth muscle cell differentiation.Type: ApplicationFiled: October 9, 2007Publication date: March 20, 2008Inventors: Toshio Ota, Takao Isogai, Tetsuo Nishikawa, Koji Hayashi, Kaoru Otsuka, Jun-Ichi Yamamoto, Shizuko Ishii, Tomoyasu Sugiyama, Ai Wakamatsu, Keiichi Nagai, Tetsuji Otsuki, Shin-Ichi Funahashi, Shoji Miyata, Kenji Sobue, Kenichiro Hayashi
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Patent number: 7279558Abstract: A cDNA fragment participating in the maintenance of smooth muscle differentiation was isolated using a culture system of chicken gizzard smooth muscle cells, the differential display method and the subtracted hybridization method. Using the obtained cDNA sequence as a query, cDNA sequences of Helix Research Institute (Japanese Patent Application No. 2000-118776) were retrieved, and thus, a novel gene “C-NT2RP3001495” was obtained. The protein encoded by this gene has two WW domains that participate in protein interactions in the N-terminal domain. Evidence suggests that this protein binds to other proteins, and thus regulates the intracellular signal transduction, gene expression, and so on, thereby participating in the maintenance of the differentiation of smooth muscle cells. This protein and compounds regulating the expression thereof are markedly useful in developing drugs for various diseases associated with abnormality in the maintenance of smooth muscle cell differentiation.Type: GrantFiled: February 4, 2005Date of Patent: October 9, 2007Assignees: Chugai Seiyaku Kabushiki KaishaInventors: Toshio Ota, Takao Isogai, Tetsuo Nishikawa, Koji Hayashi, Kaoru Otsuka, Jun-Ichi Yamamoto, Shizuko Ishii, Tomoyasu Sugiyama, Ai Wakamatsu, Keiichi Nagai, Tetsuji Otsuki, Shin-Ichi Funahashi, Shoji Miyata, Kenji Sobue, Kenichiro Hayashi
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Patent number: 7217800Abstract: A cDNA encoding a novel LTC4 receptor has been isolated. Provision of the novel protein, an LTC4 receptor, enabled binding experiments using the LTC4. By screening for compounds that modulate LTC4 receptor activity based on these binding experiments, development of drugs targeting the LTC4 receptor becomes possible.Type: GrantFiled: September 2, 2004Date of Patent: May 15, 2007Assignees: Astellas Pharma Inc., Helix Research InstituteInventors: Jun Takasaki, Masazumi Kamohara, Mitsuyuki Matsumoto, Tetsu Saito, Tohru Sugimoto, Toshio Ota, Takao Isogai, Tetsuo Nishikawa, Yuri Kawai
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Publication number: 20070105122Abstract: Primers for synthesizing full-length cDNAs and their use are provided. 5602 cDNA encoding a human protein has been isolated and nucleotide sequences of 5?-, and 3?-ends of the cDNA have been determined. Furthermore, primers for synthesizing the full-length cDNA have been provided to clarify the function of the protein encoded by the cDNA. The full-length cDNA of the present invention containing the translation start site provides information useful for analyzing the functions of the protein.Type: ApplicationFiled: August 13, 2004Publication date: May 10, 2007Inventors: Toshio Ota, Takao Isogai, Tetsuo Nishikawa, Koji Hayashi, Kaoru Saito, Junichi Yamamoto, Shizuko Ishii, Tomoyasu Sugiyama, Ai Wakamatsu, Keiichi Nagai, Tetsuji Otsuki
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Publication number: 20070082345Abstract: Novel human secretory proteins or membrane proteins, and full length cDNAs encoding the proteins are provided. 173 kinds of novel proteins and polynucleotides encoding these proteins have been isolated. The proteins of the present invention are useful as candidates for medicines or as target molecules for developing medicines. The polynucleotides of the present invention are used to produce these proteins.Type: ApplicationFiled: May 8, 2006Publication date: April 12, 2007Inventors: Toshio Ota, Takao Isogai, Tetsuo Nishikawa, Yuri Kawai, Tomoyasu Sugiyama, Koji Hayashi
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Publication number: 20070048740Abstract: Novel full-length cDNAs are provided. 1,995 cDNA derived from human have been isolated. The full-length nucleotide sequences of the cDNA and amino acid sequences encoded by the nucleotide sequences have been determined. Because the cDNA of the present invention are full-length and contain the translation start site, they provide information useful for analyzing the functions of the polypeptide.Type: ApplicationFiled: February 13, 2004Publication date: March 1, 2007Inventors: Takao Isogai, Junichi Yamamoto, Tetsuo Nishikawa, Yuko Isono, Tomoyasu Sugiyama, Tetsuji Otsuki, Ai Wakamatsu, Shizuko Ishii, Keiichi Nagai, Ryotaro Irie
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Publication number: 20060287831Abstract: One of a plurality of data display formats with different units of correlation data that are prepared in advance is automatically selected depending on the variation of the amount of data in terms of the number of items thereof. One of a plurality of display methods with different summarization levels that are prepared in advance is also automatically selected for information (about correlation data or individual events) regarding individual cells. Information about the correlation data and individual cells is then displayed. The amount of work required to repeat the operation of observing the correlation data as a whole and the detailed observation of a small amount of data is reduced in a method for visualizing correlation data concerning two events in a matrix format.Type: ApplicationFiled: July 12, 2004Publication date: December 21, 2006Inventors: Motoi Totiba, Tetsuo Nishikawa, Ken Horiuchi, Masashi Nemoto, Kenji Araki
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Patent number: 7129338Abstract: Human cDNA encoding a secretory or membrane protein useful as a candidate for developing medicine or as a target molecule for developing medicine. The expression level of the polynucleotide of the present invention increased in NT2 cells after retinoic acid-treatment. Accordingly, this cDNA is associated neurological disease.Type: GrantFiled: November 27, 2002Date of Patent: October 31, 2006Assignee: Research Association for BiotechnologyInventors: Toshio Ota, Takao Isogai, Tetsuo Nishikawa, Yuri Kawai, Tomoyasu Sugiyama, Koji Hayashi
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Publication number: 20060193497Abstract: (A) Luminance data is prepared. (B) A group of first order differential values is obtained from luminance values of said luminance data along a first direction, a group of second order differential values is obtained from the group of first order differential values, and first data is output in accordance with the group of second order differential values. There is provided a stain inspection method having high inspection correctness.Type: ApplicationFiled: February 9, 2006Publication date: August 31, 2006Applicant: Fuji Photo Film Co., Ltd.Inventors: Ichiro Matsumoto, Tetsuo Nishikawa
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Patent number: 7085651Abstract: An object of the present invention is to perform the clustering and assembling of nucleic acid base sequences at a high speed. Partial sequences 102 are extracted from each input sequence 101 and entered into a fixed-length partial sequence table 103. In the case where a sequence overlapping with a consensus sequence 104 is searched while making reference to the fixed-length partial sequence table 103 and consequently a partial sequence 102, which exactly matches with a sequence defined by a fixed length window 105 scanning along the consensus sequence, is found to be present, whether the whole input sequence can be assembled or not is determined by comparing the sequences. If it is possible to assemble the sequences, they are assembled into a consensus sequence and also joined into the same cluster. The clustering and assembling are performed by repeatedly processing this procedure based on greedy method until no unprocessed input nucleic acid base sequence is left.Type: GrantFiled: February 27, 2002Date of Patent: August 1, 2006Assignee: Hitachi, Ltd.Inventors: Tomohiro Yasuda, Tetsuo Nishikawa
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Patent number: 7047255Abstract: The present invention visualizes the contents of a plurality of documents without a lack of the listing property. Two document units are extracted from a document database and relevance degrees between individual elements of a group of the document units are calculated. The results are displayed on a two-dimensional coordinate plane depending on the relevance degree.Type: GrantFiled: February 27, 2003Date of Patent: May 16, 2006Assignee: Hitachi, Ltd.Inventors: Osamu Imaichi, Tetsuo Nishikawa, Toru Hisamitsu, Makoto Iwayama, Masakazu Fujio
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Patent number: 7029860Abstract: The present invention provides: proteins suppressing or promoting the aggregation or deposition of amyloid-? protein; polynucleotides encoding the proteins; a method for screening a compound suppressing or promoting the aggregation or deposition of amyloid-? protein; and therapeutic agents for treating or preventing Alzheimer's diseases comprising a compound that regulates the activity of a protein suppressing or promoting the aggregation or deposition of amyloid-? protein.Type: GrantFiled: December 17, 2004Date of Patent: April 18, 2006Assignee: Fujisawa Pharmaceutical Co., Ltd.Inventors: Toshio Ota, Takao Isogai, Tetsuo Nishikawa, Yuri Hio, Mayako Yamazaki, Susumu Satoh, Hiroyuki Arakawa, Masahiko Morita
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Patent number: 7010141Abstract: In a speaker device 10 having: a magnetic circuit 13 including a magnet 14 and a yoke 11; a voice coil 16 which is placed in a magnetic gap 12 of the magnetic circuit 13; and a diaphragm 17 which is vibrating available in a state where the diaphragm is coupled with the voice coil 16, a peripheral edge of the diaphragm 17 being fixed to a housing 20, a damper holder 30 is disposed in a portion where a damper 27 is attached to the housing 20. The damper holder 30 is in point contact with the housing 20 via three or more projections 31 which are disposed on one of the damper holder 30 and the housing 20. Preferably, the damper holder 30 is made of a hybrid material of a resin (polypropylene) and tungsten, and has a specific gravity of 10.0 or larger.Type: GrantFiled: November 21, 2003Date of Patent: March 7, 2006Assignees: Pioneer Corporation, Tohoku Pioneer CorporationInventors: Hideaki Sugiura, Taizo Nakata, Tetsuo Nishikawa
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Publication number: 20050250144Abstract: Selection of clones having the kinase and/or phosphatase-like structure from clones which had been isolated and the structures thereof had been determined in the Helix Research Institute (helix clones; Japanese Patent Application No. 2000-183767) was conducted. Two novel genes were provided by carrying out homology search for all the helix clones by using the amino acid sequences of known kinases and phosphatases as queries. The genes are expected to be involved in intracellular signal transduction. The physiological functions of the inventive genes can be tested by using reporter gene assay systems capable of detecting signal transduction. The proteins of the present invention are useful as target molecules in drug discovery and in the development of new pharmaceuticals.Type: ApplicationFiled: April 19, 2005Publication date: November 10, 2005Inventors: Toshio Ota, Takao Isogai, Tetsuo Nishikawa, Koji Hayashi, Kaoru Otsuka, Jun-Ichi Yamamoto, Shizuko Ishii, Tomoyasu Sugiyama, Ai Wakamatsu, Keiichi Nagai, Tetsuji Otsuki, Shin-Ichi Funahashi, Chiaki Senoo, Jin-Ichi Nezu
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Patent number: 6960435Abstract: The present invention provides: proteins suppressing or promoting the aggregation or deposition of amyloid-? protein; polynucleotides encoding the proteins; a method for screening a compound suppressing or promoting the aggregation or deposition of amyloid-? protein; and therapeutic agents for treating or preventing Alzheimer's diseases comprising a compound that regulates the activity of a protein suppressing or promoting the aggregation or deposition of amyloid-? protein.Type: GrantFiled: July 6, 2000Date of Patent: November 1, 2005Assignee: Fujisawa Pharmaceutical Co., Ltd.Inventors: Toshio Ota, Takao Isogai, Tetsuo Nishikawa, Yuri Hio, Mayako Yamazaki, Susumu Satoh, Hiroyuki Arakawa, Masahiko Morita
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Publication number: 20050214813Abstract: The present invention provides: proteins suppressing or promoting the aggregation or deposition of amyloid-? protein; polynucleotides encoding the proteins; a method for screening a compound suppressing or promoting the aggregation or deposition of amyloid-? protein; and therapeutic agents for treating or preventing Alzheimer's diseases comprising a compound that regulates the activity of a protein suppressing or promoting the aggregation or deposition of amyloid-? protein.Type: ApplicationFiled: December 17, 2004Publication date: September 29, 2005Applicant: Fujisawa Pharmaceutical Co. Ltd.Inventors: Toshio Ota, Takao Isogai, Tetsuo Nishikawa, Yuri Hio, Mayako Yamazaki, Susumu Satoh, Hiroyuki Arakawa, Masahiko Morita