Patents by Inventor Tetsuo Yokoyama

Tetsuo Yokoyama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100229634
    Abstract: Disclosed is an improved post-column fluorimetric determination-boric acid complex anion exchange method which allows analysis of mannose-6-phosphate. The disclosed method is a method for separation analysis of reducing sugars using column chromatography, comprising loading a sample onto an anion exchange column, washing the column by allowing to flow a sufficient volume of a first mobile phase consisting of an aqueous solution of a predetermined concentration of boric acid containing a predetermined concentration of a water-soluble inorganic salt through the column, supplying a second mobile phase with an elevated concentration of the salt to elute the reducing sugars, adding to the eluate a basic amino acid, heating, and continuously measuring and recording the intensity of fluorescent light emitted under irradiation with excitation light.
    Type: Application
    Filed: March 12, 2010
    Publication date: September 16, 2010
    Applicant: JCR PHARMACEUTICALS CO., LTD.
    Inventor: Tetsuo YOKOYAMA
  • Patent number: 7235253
    Abstract: A method is disclosed for stabilizing a physiologically active peptide in a process of preparing a powder containing the physiologically active peptide by drying an aqueous liquid containing the physiologically active peptide, wherein the method comprises adding to the aqueous liquid at least one compound selected from the group consisting of a nonionic surfactant, a water-soluble, nonionic, organic binder, hydrogenated lecithin, and mannitol.
    Type: Grant
    Filed: November 28, 2001
    Date of Patent: June 26, 2007
    Assignee: JCR Pharmaceuticals Co., Ltd.
    Inventors: Yoshinobu Hanyu, Mariko Okada, Chihiro Shindo, Satoshi Nishimuro, Tetsuo Yokoyama, Masato Horie
  • Publication number: 20030089696
    Abstract: An automated soldering system with an intelligent power supply that can automatically configure the power output to interchangeable soldering cartridges, where the soldering cartridges include readable information to allow the power supply to properly power the cartridge to achieve a desired, entered operating temperature. The system includes a cartridge with an identifier that contains information particular to that cartridge, a reader able to read that information, and an indicator positioned on a connector into which the cartridge is inserted.
    Type: Application
    Filed: November 14, 2001
    Publication date: May 15, 2003
    Inventors: Tetsuo Yokoyama, Mitsuhiko Miyazaki, Yoshihiro Hagihara
  • Patent number: 6563087
    Abstract: An automated soldering system with an intelligent power supply that can automatically configure the power output to interchangeable soldering cartridges, where the soldering cartridges include readable information to allow the power supply to properly power the cartridge to achieve a desired, entered operating temperature. The system includes a cartridge with an identifier that contains information particular to that cartridge, a reader able to read that information, and an indicator positioned on a connector into which the cartridge is inserted.
    Type: Grant
    Filed: November 14, 2001
    Date of Patent: May 13, 2003
    Assignee: Hakko Corporation
    Inventors: Tetsuo Yokoyama, Mitsuhiko Miyazaki, Yoshihiro Hagihara
  • Publication number: 20030044909
    Abstract: The present invention provides materials capable of screening human melatonin which comprise an animal cell containing an expression plasmid for the gene encoding a human melatonin receptor protein and having said protein expressed therein, as well as a method for screening the same, thus permitting not only human melatonin but also hormones showing affinity for the same, and their agonists or antagonists to be screened with an enhanced degree of precision.
    Type: Application
    Filed: March 29, 2002
    Publication date: March 6, 2003
    Applicant: JCR PHARMACEUTICALS Co., Ltd.
    Inventors: Tetsuo Yokoyama, Hiroyuki Shirono, Jun-Ichi Koga
  • Publication number: 20020058624
    Abstract: A method is disclosed for stabilizing a physiologically active peptide in a process of preparing a powder containing the physiologically active peptide by drying an aqueous liquid containing the physiologically active peptide, wherein the method comprises adding to the aqueous liquid at least one compound selected from the group consisting of a nonionic surfactant, a water-soluble, nonionic, organic binder, hydrogenated lecithin, and mannitol.
    Type: Application
    Filed: November 28, 2001
    Publication date: May 16, 2002
    Applicant: JCR PHARMACEUTICALS CO., Lrd.
    Inventors: Yoshinobu Hanyu, Mariko Okada, Chihiro Shindo, Satoshi Nishimuro, Tetsuo Yokoyama, Masato Horie
  • Publication number: 20020009789
    Abstract: A method is disclosed for stabilizing a physiologically active peptide in a process of preparing a powder containing the physiologically active peptide by drying an aqueous liquid containing the physiologically active peptide, wherein the method comprises adding to the aqueous liquid at least one compound selected from the group consisting of a nonionic surfactant, a water-soluble, nonionic, organic binder, hydrogenated lecithin, and mannitol.
    Type: Application
    Filed: March 19, 2001
    Publication date: January 24, 2002
    Applicant: JCR PHARMACEUTICALS CO., Ltd.
    Inventors: Yoshinobu Hanyu, Mariko Okada, Chihiro Shindo, Satoshi Nishimuro, Tetsuo Yokoyama, Masato Horie
  • Patent number: 6326189
    Abstract: The sample vessel 1 comprises plurality of vessels 1a. The vessel 1a comprises an opening for sample inlet 3, a liquid sample outlet 4, and a silicon oxide composite particles structural body 2 is arranged at the bottom of the vessel 1a, i.e. the liquid sample outlet 4. The silicon oxide composite particles structural body 2 is a structural body composed of a composite made of plural silicon oxide particles having smaller diameter combined with a resin particle having larger diameter. Accordingly, even if the diameter of the silicon oxide particles 7 is set small in order to maintain the nucleic acid combination ability high, the presence of the resin particles 6 having a large diameter makes it possible to ensure the liquid conduction path, and the nucleic acid separating vessel, which is capable of suppressing decrease of the B/F separating velocity with maintaining the nucleic acid combining ability high can be realized.
    Type: Grant
    Filed: March 2, 2000
    Date of Patent: December 4, 2001
    Assignee: Hitachi, Ltd.
    Inventors: Shinichi Fukuzono, Tetsuo Yokoyama, Yukiko Ikeda, Yoshishige Endo
  • Patent number: 6162356
    Abstract: Composite particles formed from resin particles and silica particles (amount of silica particles: 0.2 to 10 wt. % on the basis of the resin particles) in an apparatus for formation of composite particles are placed in a PTFE mold and heat treated to weld the resin particles to one another, thereby forming a structural element, which is dipped in an ethyl silicate solution containing monodispersed silica particles, then taken out of the solution and subjected to further heat treatment to form an ultimate structural element, which is sealed in a tip case, whereby a tip can be produced at a low cost and used to separate nucleic acid from a liquid sample for a short time at a high recovery rate without any defects such as breaking, etc.
    Type: Grant
    Filed: March 19, 1999
    Date of Patent: December 19, 2000
    Assignee: Hitachi, Ltd.
    Inventors: Yukiko Ikeda, Yoshishige Endo, Yasuhiro Yoshimura, Takao Terayama, Kenji Yasuda, Toshinari Sakurai, Tetsuo Yokoyama, Takanori Aono
  • Patent number: 6085998
    Abstract: A dismountable hot air nozzle comprising a mounting adapter (2) to be secured to a nozzle pipe (92), a generally annular adapter spring (59) cut in one position and having engaging bosses (59a) adapted to project from the inner circumferential surface of the mounting adapter when assembled, a stopper pin (58) projecting out of the inner circumferential surface of the mounting adapter in a position adjacent to the engaging boss when assembled, and a nozzle holder (3) carrying a nozzle (8) at its lower end and formed as a cylindrical member (6) adapted to fit into the mounting adapter at its upper end, the upper end of the cylindrical member being formed with recesses (61) engageable with the stopper pin (58) at their circumferentially lateral edges and the cylindrical member being further formed with slits (62) engageable with the engaging bosses (59a) as the engageable circumferentially lateral edge of recess (61) is engaged by the stopper pin (58).
    Type: Grant
    Filed: February 5, 1999
    Date of Patent: July 11, 2000
    Assignee: Hakko Corporation
    Inventor: Tetsuo Yokoyama
  • Patent number: 6064391
    Abstract: To efficiently, 3-dimensionally, perspectively project and display the extracting processing procedure of a predetermined region on a 3-dimensional image, the extracting process is executed while observing the displayed image. Further, the process is interrupted as necessary so that the process can progress or be returned. The result of the extraction at the interruption time point is edited on a 2-dimensional image and the result of the edition is immediately reflected onto the 3-dimensional image, so that whether the edition is proper or improper can be decided.
    Type: Grant
    Filed: November 26, 1991
    Date of Patent: May 16, 2000
    Assignee: Hitachi, Ltd.
    Inventors: Koichi Sano, Hiroyuki Sekiguchi, Tetsuo Yokoyama
  • Patent number: 5857726
    Abstract: An instrument panel is formed symmertrically with respect to a center of the panel. The instrument panel comprises a pair of recesses defined by left and right reinforcing/partition walls, and a pair of lower openings located under the recesses. A meter unit is mounted in the recess to oppose the driver seat. An under cover is mounted in the lower opening which is to oppose the driver seat. The under cover is formed with a hole through which a steering shaft is adapted to be passed. A tray is mounted in the recess which is to oppose the front passenger seat. A glove box is mounted in the lower opening which is to oppose the front passenger seat. The walls for defining the recesses of the instrument panel have a common fixing section usable for mounting any of the meter unit and the tray.
    Type: Grant
    Filed: March 14, 1997
    Date of Patent: January 12, 1999
    Assignee: Mitsubishi Jidosha Kogyo Kabushiki Kaisha
    Inventors: Tetsuo Yokoyama, Mitsuhisa Fujino, Yasunobu Yamazaki
  • Patent number: 5795633
    Abstract: A material composition comprising (a) a poly-functional isocyanate, (b) a compound having MW of 600-3,500 and two functional groups polymerizable with an isocyanate group, (c) a compound having MW below 500 and two functional groups polymerizable with an isocyanate group, and (d) a compound having MW below 700 and at least three functional groups polymerizable with an isocyanate group. A shaped polymeric material is made by mixing and heating (a) with part of (b) to give a prepolymer, adding the remainder of (b), (c) and (d) to the prepolymer, and then heating the mixture to effect additional polymerization of (a), (b), (c) and (d). The shaped polymeric material has enhanced tear strength, tensile strength and elongation, reduced permanent set and low toxicity, and suitable for parts for which high stretchability is required.
    Type: Grant
    Filed: February 21, 1997
    Date of Patent: August 18, 1998
    Assignee: Nippon Zeon Co., Ltd.
    Inventors: Tetsuo Yokoyama, Kyoko Hiraoka, Hiroto Kidokoro
  • Patent number: 5553207
    Abstract: In a region extraction to be achieved by a concatenated region expansion processing, to improve reliability of extraction results and to reduce loads imposed on the operator, when a region other than an objective region is extracted as a result of the region extraction, a point belonging to the region other than the objective region is specified in a three-dimensional display image to execute deletion of the overflow region.
    Type: Grant
    Filed: May 24, 1994
    Date of Patent: September 3, 1996
    Assignee: Hitachi, Ltd.
    Inventors: Hiroyuki Sekiguchi, Koichi Sano, Tetsuo Yokoyama
  • Patent number: 5427100
    Abstract: Disclosed is a method for automatically determining the median line of a selected region of a human body so as to simplify complex imaging required hithero for a magnetic resonance imaging apparatus, and, in the method, an artifact of the imaged selected region of the human body is utilized to automatically determine the median line. For example, two artifacts 1010 and 1020 intersecting each other appear from the superior sagittal sinus as shown in FIG. 1 when the direction of phase encoding is changed. By subtracting one of these artifacts 1010 and 1020 from the other and calculating the absolute value of the result of subtraction, the point 1030 of intersection of the artifacts determines the location of the superior sagittal sinus which is the source of apperance of the artifacts, so that the median line can be automatically determined on the basis of the result of determination of location of the superior sagittal sinus.
    Type: Grant
    Filed: February 3, 1993
    Date of Patent: June 27, 1995
    Assignee: Hitachi, Ltd.
    Inventors: Noboru Higashi, Koichi Sano, Tetsuo Yokoyama
  • Patent number: 5319551
    Abstract: In order to ensure that region extraction for extracting a specified internal organ can be effected with high reliability, a region expansion method is applied by using a combination of an expansion condition taking the local density change into consideration and an expansion condition taking the global density change into consideration.
    Type: Grant
    Filed: October 24, 1990
    Date of Patent: June 7, 1994
    Assignee: Hitachi, Ltd.
    Inventors: Hiroyuki Sekiguchi, Koichi Sano, Tetsuo Yokoyama
  • Patent number: 5277182
    Abstract: A method for imaging the coronary artery of a living body using nuclear magnetic resonance, wherein a patient is located in a static magneic field and the heart cycle of the patient is detected with the heart dilation period of the patient being determined in accordance with the detected heart cycle. Then, the coronary artery of the patient is portrayed on the nuclear magnetic resonance signal generated by applying high-frequency energy to the patient during the determined heart dilation period.
    Type: Grant
    Filed: June 24, 1991
    Date of Patent: January 11, 1994
    Assignee: Hitachi, Ltd.
    Inventors: Hideaki Koizumi, Ryuzaburo Takeda, Hideki Kohno, Tetsuo Yokoyama, Yoshiyuki Miyamoto, Koichi Sano
  • Patent number: 5275164
    Abstract: A method and apparatus for MRI imaging capable of reducing the time between end of measurement and completion of image reconstruction by performing part of image reconstruction calculation in parallel with measurement of magnetic resonance signals, which particularly performs image reconstruction calculation up to (N-1) dimensions of N-dimensional image reconstruction calculation in parallel with measurement of signals and performs the image reconstruction calculation for the remaining one-dimensional direction after the measurement has been finished.
    Type: Grant
    Filed: July 28, 1989
    Date of Patent: January 4, 1994
    Assignee: Hitachi, Ltd.
    Inventors: Akira Maeda, Koichi Sano, Tetsuo Yokoyama, Hideaki Koizumi
  • Patent number: D590853
    Type: Grant
    Filed: November 10, 2007
    Date of Patent: April 21, 2009
    Assignee: Hakko Corporation
    Inventors: Tetsuo Yokoyama, Toshikazu Mochizuki
  • Patent number: RE34495
    Abstract: A slice selection gradient magnetic field used in a pulse sequence for generating a spin echo signal is applied in such a fashion that its polarity at the time of a 90.degree. pulse becomes opposite to the one at the time of 180.degree. pulse, in order to expand a dynamic range of blood flow speed measurement. When the blood flow speed contains a component in a slice vertical direction, the gradient magnetic field in the slice vertical direction is adjusted so that the phase changes of two sets of flow encoded pulses contained in the slice vertical direction are opposite to each other.The flow speed in the direction of the readout gradient magnetic field, which is a lateral direction of the slice plane, is purely measured by canceling influences of the flow in the slice vertical direction.
    Type: Grant
    Filed: July 3, 1991
    Date of Patent: January 4, 1994
    Assignee: Hitachi, Ltd.
    Inventors: Koichi Sano, Tetsuo Yokoyama, Ryuzaburo Takeda, Yasuhiko Ozawa, Shinichi Sato, Hideaki Koizumi