Patents by Inventor Tetsuya Kawahara
Tetsuya Kawahara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 7410971Abstract: A compound represented by the following general formula (1) or (100), a salt thereof or a hydrate of the foregoing has excellent cell adhesion inhibitory action or cell infiltration inhibitory action, and is useful as a therapeutic or prophylactic agent for various inflammatory diseases and autoimmune diseases associated with adhesion and infiltration of leukocytes, such as inflammatory bowel disease (particularly ulcerative colitis or Crohn's disease), irritable bowel syndrome, rheumatoid arthritis, psoriasis, multiple sclerosis, asthma and atopic dermatitis. wherein R10 represents optionally substituted cycloalkyl, etc., R20-23 represent hydrogen, alkyl, alkoxy, etc., R30-32 represent hydrogen, alkyl, oxo, etc., and R40 represents optionally substituted alkyl, etc.Type: GrantFiled: December 24, 2004Date of Patent: August 12, 2008Assignee: Eisai R&D Management Co., Ltd.Inventors: Tetsuya Kawahara, Makoto Kotake, Naoki Yoneda, Shinsuke Hirota, Masayoshi Ohkuro
-
Patent number: 7350039Abstract: A CPU 290 of a recording/reproducing device 200 acquires automatic video recording request information, and generates, based on EPG data previously acquired, new automatic reservation information incorporating basic video recording information with video recording start date and time or video recording finish date and time for contents corresponding to a keyword in the automatic video recording reservation request information and priority information indicating that the priority is “intermediate”.Type: GrantFiled: June 1, 2005Date of Patent: March 25, 2008Assignee: Pioneer CorporationInventors: Yukio Numakami, Tetsuya Kawahara, Motooki Sugihara, Koji Matsuura, Naoaki Horiuchi
-
Patent number: 7304083Abstract: A 2-iminoimidazole derivative represented by the formula: {wherein R1, R2 and R3 represent hydrogen, optionally substituted C1-6 alkyl, etc.; R6 represents hydrogen, C1-6 alkyl, C1-6 alkyloxycarbonyl, etc.; Y1 represents a single bond, —CH2—, etc.; Y2 represents a single bond, —CO—, etc.; and Ar represents hydrogen, a group represented by the formula: [wherein R10–R14 represent hydrogen, C1-6 alkyl, hydroxyl, C1-6 alkoxy, etc., and R11 and R12 or R12 and R13 may bond together to form a 5- to 8-membered heterocycle], etc.}or salt thereof.Type: GrantFiled: April 19, 2002Date of Patent: December 4, 2007Assignee: Eisai R&D Management Co., Ltd.Inventors: Shuichi Suzuki, Makoto Kotake, Mitsuaki Miyamoto, Tetsuya Kawahara, Akiharu Kajiwara, Ieharu Hishinuma, Kazuo Okano, Syuhei Miyazawa, Richard Clark, Fumihiro Ozaki, Nobuaki Sato, Masanobu Shinoda, Atsushi Kamada, Itaru Tsukada, Fumiyoshi Matsuura, Yoshimitsu Naoe, Taro Terauchi, Yoshiaki Oohashi, Osamu Ito, Hiroshi Tanaka, Takashi Musha, Motoji Kogushi, Tsutomu Kawata, Toshiyuki Matsuoka, Hiroko Kobayashi, Ken-ichi Chiba, Akifumi Kimura, Naoto Ono
-
Patent number: 7244730Abstract: A 2-iminopyrrolidine derivative represented by the formula: {wherein ring B represents a benzene ring, pyridine ring, etc.; R101–R103 represent hydrogen, halogen, C1-6 alkyl, etc.; R5 represents hydrogen, C1-6 alkyl, C1-6 alkoxy-C1-6 alkyl, etc.; R6 represents hydrogen, C1-6 alkyl, C1-6 alkyloxycarbonyl, etc.; Y1 represents a single bond, —CH2—, etc.; Y2 represents a single bond, —CO—, etc.; and Ar represents hydrogen, a group represented by the formula: [wherein R10—R14 represent hydrogen, C1-6 alkyl, hydroxyl, C1-6 alkoxy, etc.; and R11 and R12 or R12 and R13 may bond together to form a 5- to 8-membered heterocyclic ring], etc.}, or a salt thereof.Type: GrantFiled: April 19, 2002Date of Patent: July 17, 2007Assignee: Eisai Co., LtdInventors: Shuichi Suzuki, Makoto Kotake, Mitsuaki Miyamoto, Tetsuya Kawahara, Akiharu Kajiwara, Ieharu Hishinuma, Kazuo Okano, Syuhei Miyazawa, Richard Clark, Fumihiro Ozaki, Nobuaki Sato, Masanobu Shinoda, Atsushi Kamada, Itaru Tsukada, Fumiyoshi Matsuura, Yoshimitsu Naoe, Taro Terauchi, Yoshiaki Oohashi, Osamu Ito, Hiroshi Tanaka, Takashi Musya, Motoji Kogushi, Tsutomu Kawada, Toshiyuki Matsuoka, Hiroko Kobayashi, Ken-ichi Chiba, Akifumi Kimura, Naoto Ono
-
Publication number: 20070112002Abstract: A compound represented by the following general formula (1) or (100), a salt thereof or a hydrate of the foregoing has excellent cell adhesion inhibitory action or cell infiltration inhibitory action, and is useful as a therapeutic or prophylactic agent for various inflammatory diseases and autoimmune diseases associated with adhesion and infiltration of leukocytes, such as inflammatory bowel disease (particularly ulcerative colitis or Crohn's disease), irritable bowel syndrome, rheumatoid arthritis, psoriasis, multiple sclerosis, asthma and atopic dermatitis. wherein R10 represents optionally substituted cycloalkyl, etc., R20-23 represent hydrogen, alkyl, alkoxy, etc., R30-32 represent hydrogen, alkyl, oxo, etc., and R40 represents optionally substituted alkyl, etc.Type: ApplicationFiled: December 24, 2004Publication date: May 17, 2007Inventors: Tetsuya Kawahara, Makoto Kotake, Naoki Yoneda, Shinsuke Hirota, Masayoshi Ohkuro
-
Publication number: 20070015782Abstract: An object of the present invention is to provide a novel chemical compound useful as a therapeutic or prophylactic agent for acid-related diseases, having an excellent inhibitory effect against gastric acid secretion, an excellent effect of maintaining the inhibitory effect against gastric acid secretion, thereby maintaining intragastric pH high for a long time, and having more safety and appropriate physicochemical stability. Provided is a compound represented by where R1 and R3 may be the same or different and each represent a hydrogen atom or a C1-C6 alkyl group; R2 represents (5,5-dimethyl-1,3-dioxan-2-yl)methoxy group, 5,7-dioxaspiro[2.5]oct-6-ylmethoxy group, 1,5,9-trioxaspiro[5.5]undec-3-ylmethoxy group, or (2,2-dimethyl-1,3-dioxan-5-yl)methoxy group; R4, R5, R6 and R7 represent a hydrogen atom, halogen atom, C1-C6 alkyl group, C1-C6 haloalkyl group, C1-C6 alkoxy group or C1-C6 haloalkoxy group; and W1 represents a single bond, methylene or ethylene group, a salt thereof or a solvate of these.Type: ApplicationFiled: April 14, 2006Publication date: January 18, 2007Inventors: Shuhei Miyazawa, Masanobu Shinoda, Tetsuya Kawahara, Nobuhisa Watanabe, Hitoshi Harada, Daisuke Iida, Hiroki Terauchi, Junichi Nagakawa, Hideaki Fujisaki, Atsuhiko Kubota, Masato Ueda
-
Publication number: 20070010542Abstract: An object of the present invention is to provide a novel chemical compound useful as a therapeutic or prophylactic agent for acid-related diseases, having an excellent inhibitory effect against gastric acid secretion, an excellent effect of maintaining the inhibitory effect against gastric acid secretion, thereby maintaining intragastric pH high for a long time, and having more safety and appropriate physicochemical stability. Provided is a compound represented by where R1 and R3 may be the same or different and each represent a hydrogen atom or a C1-C6 alkyl group; R2 represents (5,5-dimethyl-1,3-dioxan-2-yl)methoxy group, 5,7-dioxaspiro[2.5]oct-6-ylmethoxy group, 1,5,9-trioxaspiro[5.5]undec-3-ylmethoxy group, or (2,2-dimethyl-1,3-dioxan-5-yl)methoxy group; R4, R5, R6 and R7 represent a hydrogen atom, halogen atom, C1-C6 alkyl group, C1-C6 haloalkyl group, C1-C6 alkoxy group or C1-C6 haloalkoxy group; and W1 represents a single bond, methylene or ethylene group, a salt thereof or a solvate of these.Type: ApplicationFiled: September 14, 2006Publication date: January 11, 2007Inventors: Shuhei Miyazawa, Masanobu Shinoda, Tetsuya Kawahara, Nobuhisa Watanabe, Hitoshi Harada, Daisuke Iida, Hiroki Terauchi, Junichi Nagakawa, Hideaki Fujisaki, Atsuhiko Kubota, Masato Ueda
-
Publication number: 20060281747Abstract: A compound represented by the following general formula (1) or (100), a salt thereof or a hydrate of the foregoing has excellent cell adhesion inhibitory action and cell infiltration inhibitory action. wherein R10 represents 5- to 10-membered cycloalkyl etc. optionally substituted with hydroxyl etc., R30, R31 and R32 may be the same or different and each represents hydrogen etc., R40 represents C1-10 alkyl etc. optionally substituted with hydroxyl etc., n represents an integer of 0, 1 or 2, X1 represents CH or nitrogen, and R20, R21, R22 and R23 may be the same or different and each represents hydrogen etc.Type: ApplicationFiled: June 14, 2006Publication date: December 14, 2006Inventors: Tetsuya Kawahara, Makoto Kotake, Naoki Yoneda, Shinsuke Hirota, Masayoshi Ohkuro
-
Publication number: 20060276465Abstract: A compound represented by the following general formula (1) or (100), a salt thereof or a hydrate of the foregoing has excellent cell adhesion inhibitory action or cell infiltration inhibitory action, and is useful as a therapeutic or prophylactic agent for various inflammatory diseases and autoimmune diseases associated with adhesion and infiltration of leukocytes, such as inflammatory bowel disease (particularly ulcerative colitis or Crohn's disease), irritable bowel syndrome, rheumatoid arthritis, psoriasis, multiple sclerosis, asthma and atopic dermatitis. wherein R10 represents optionally substituted cycloalkyl, etc., R20-23 represent hydrogen, alkyl, alkoxy, etc., R30-32 represent hydrogen, alkyl, oxo, etc., and R40 represents optionally substituted alkyl, etc.Type: ApplicationFiled: June 23, 2006Publication date: December 7, 2006Applicant: Eisai R&D Management Co., Ltd.Inventors: Tetsuya Kawahara, Makoto Kotake, Naoki Yoneda, Shinsuke Hirota, Masayoshi Ohkuro
-
Publication number: 20050289616Abstract: A storing-reproducing unit 200 recognizes a free space of a contents storage area by a storage-area-administrating device, sets a recording timing duration based on the recognized free space of the contents storage area, and selects a schedule information of a contents to be recorded from recording schedule list information. Hence, frequency of storing the contents in the HDD 270 can be reduced, thereby avoiding that the contents which has not yet watched is erased by self-erasing, so that the contents can be effectively recorded. Therefore, a user can secure flexibility in time in watching the contents.Type: ApplicationFiled: June 2, 2005Publication date: December 29, 2005Applicant: PIONEER CORPORATIONInventors: Naoaki Horiuchi, Motooki Sugihara, Tetsuya Kawahara, Harumi Nakamura, Hideki Nagata
-
Publication number: 20050289594Abstract: A CPU 290 of a recording/reproducing device 200 acquires automatic video recording request information, and generates, based on EPG data previously acquired, new automatic reservation information incorporating basic video recording information with video recording start date and time or video recording finish date and time for contents corresponding to a keyword in the automatic video recording reservation request information and priority information indicating that the priority is “intermediate”.Type: ApplicationFiled: June 1, 2005Publication date: December 29, 2005Applicant: PIONEER CORPORATIONInventors: Yukio Numakami, Tetsuya Kawahara, Motooki Sugihara, Koji Matsuura, Naoaki Horiuchi
-
Publication number: 20050289597Abstract: A CPU 290 of a recording/reproducing device 200 make a recording section 251 record contents reserved by a user for video recording in an HDD 270, and sets remaining time until the contents is automatically deleted. The CPU 290 determines, when a period T is over, whether access to the contents has been carried out or not, and adds additional time D to the remaining time when the CPU 290 determines that the access has been made, and subtracts the period T from the remaining time when the CPU 290 determines that the access has not been made. The CPU 290 executes the afore-mentioned processing once in each period T, and automatically deletes the contents from the HDD 270 when the CPU 290 recognizes that the remaining time is zero or below.Type: ApplicationFiled: June 1, 2005Publication date: December 29, 2005Applicant: PIONEER CORPORATIONInventors: Tetsuya Kawahara, Yukio Numakami, Naoaki Horiuchi, Motooki Sugihara, Masaki Kurihara
-
Publication number: 20050289600Abstract: When request information for receiving or reproducing contents data of a TV program of a predetermined detail due to an input on an input unit 260 of a recording/reproducing device 200 is recognized, a genre or a keyword for the requested contents data is recognized. A basic program information about the genre or the keyword is searched based on a program information table generated from EPG data. By generating history information in which the genre and the keyword are associated, and computing an appearance frequency of the combination, a user's preference can be judged. The contents data is received based on the basic program information including requested genre or information and corresponding to the history information with high appearance frequency.Type: ApplicationFiled: June 1, 2005Publication date: December 29, 2005Applicant: PIONEER CORPORATIONInventors: Tetsuya Kawahara, Yukio Numakami, Harumi Nakamura, Koji Matsuura, Tomoharu Kirihara
-
Publication number: 20050289599Abstract: When a request for receiving or reproducing contents data of a TV program of a predetermined detail based on an input on an input unit 260 of a recording/reproducing device 200 is recognized, a related keyword related to a keyword as a searching request is recognized. Program information is narrowed, from program information including the keyword and the related keyword in accordance with a priority based on an appearance frequency as a history of the related keyword for the keyword. Since the detail of the detected program information corresponds to the priority, improper searching of the program information can be prevented, so that the program information can be selected appropriately, and proper contents data can be retrieved easily.Type: ApplicationFiled: June 1, 2005Publication date: December 29, 2005Applicant: PIONEER CORPORATIONInventors: Koji Matsuura, Harumi Nakamura, Tetsuya Kawahara, Wakako Nagata, Yukio Numkami
-
Publication number: 20050261291Abstract: In one aspect, the present invention provides compounds having formula (1) or (100), a salt thereof or a hydrate of the foregoing, which compounds exhibit excellent cell adhesion inhibitory action or cell infiltration inhibitory action, and are useful as therapeutic or prophylactic agents for various inflammatory diseases and autoimmune diseases associated with adhesion and infiltration of leukocytes, such as inflammatory bowel disease (particularly ulcerative colitis or Crohn's disease), irritable bowel syndrome; rheumatoid arthritis, psoriasis, multiple sclerosis, asthma and atopic dermatitis. wherein R10 represents optionally substituted cycloalkyl, etc., R20-23 represent hydrogen, alkyl, alkoxy, etc., R30-32 represent hydrogen, alkyl, oxo, etc., and R40 represents optionally substituted alkyl, etc.Type: ApplicationFiled: December 27, 2004Publication date: November 24, 2005Inventors: Tetsuya Kawahara, Makoto Kotake, Naoki Yoneda, Shinsuke Hirota, Masayoshi Ohkuro
-
Publication number: 20050245592Abstract: A 2-iminopyrrolidine derivative represented by the formula: {wherein ring B represents a benzene ring, pyridine ring, etc.; R101-R103 represent hydrogen, halogen, C1-6 alkyl, etc.; R5 represents hydrogen, C1-6 alkyl, C1-6 alkoxy-C1-6 alkyl, etc.; R6 represents hydrogen, C1-6 alkyl, C1-6 alkyloxycarbonyl, etc.; Y1 represents a single bond, —CH2—, etc.; Y2 represents a single bond, —CO—, etc.; and Ar represents hydrogen, a group represented by the formula: [wherein R10-R14 represent hydrogen, C1-6 alkyl, hydroxyl, C1-6 alkoxy, etc.; and R11 and R12 or R12 and R13 may bond together to form a 5- to 8-membered heterocyclic ring], etc.}, or a salt thereof.Type: ApplicationFiled: June 22, 2005Publication date: November 3, 2005Inventors: Shuichi Suzuki, Makoto Kotake, Mitsuaki Miyamoto, Tetsuya Kawahara, Akiharu Kajiwara, Ieharu Hishinuma, Kazuo Okano, Syuhei Miyazawa, Richard Clark, Fumihiro Ozaki, Nobuaki Sato, Masanobu Shinoda, Atsushi Kamada, Itaru Tsukada, Fumiyoshi Matsuura, Yoshimitsu Naoe, Taro Terauchi, Yoshiaki Oohashi, Osamu Ito, Hiroshi Tanaka, Takashi Musha, Motoji Kogushi, Tsutomu Kawata, Toshiyuki Matsuoka, Hiroko Kobayashi, Ken-ichi Chiba, Akifumi Kimura, Naoto Ono
-
Publication number: 20050004197Abstract: A 2-iminoimidazole derivative represented by the formula: {wherein R1, R2 and R3 represent hydrogen, optionally substituted C1-6 alkyl, etc.; R6 represents hydrogen, C1-6 alkyl, C1-6 alkyloxycarbonyl, etc.; Y1 represents a single bond, —CH2—, etc.; Y2 represents a single bond, —CO—, etc.; and Ar represents hydrogen, a group represented by the formula: [wherein R10-R14 represent hydrogen, C1-6 alkyl, hydroxyl, C1-6 alkoxy, etc., and R11 and R12 or R12 and R13 may bond together to form a 5- to 8-membered heterocycle], etc.} or salt thereof.Type: ApplicationFiled: April 19, 2002Publication date: January 6, 2005Inventors: Shichi Suzuki, Makoto Kotake, Mitsuaki Miyamoto, Tetsuya Kawahara, Akiharu Kajiwara, Ieharu Hishinuma, Kazuo Okano, Syuhei Miyazawa, Richard Clark, Fumuhiro Ozaki, Nobuaki Sato, Masanobu Shinoda, Atsushi Kamada, Itaru Tsukuda, Fumiyoshi Maatsuura, Yoshimitsu Naoe, Taro Terauchi, Yoshiaki Oohashi, Osamu Ito, Hiroshi Tanaka, Takashi Musha, Motoji Kogushi, Tsutomu Kawata, Toshiyuki Matsuoka, Hiroko Kobayashi, Ken-Ichi Chiba, Akifumi Kimura, Naoto Ono
-
Publication number: 20050004204Abstract: A 2-iminopyrrolidine derivative represented by the formula: {wherein ring B represents a benzene ring, pyridine ring, etc.; R101-R103 represent hydrogen, halogen, C1-6 alkyl, etc.; R5 represents hydrogen, C1-6 alkyl, C1-6 alkoxy-C1-6 alkyl, etc.; R6 represents hydrogen, C1-6 alkyl, C1-6 alkyloxycarbonyl, etc.; Y1 represents a single bond, —CH2—, etc.; Y2 represents a single bond, —CO—, etc.; and Ar represents hydrogen, a group represented by the formula: [wherein R10—R14 represent hydrogen, C1-6 alkyl, hydroxyl, C1-6 alkoxy, etc.; and R11 and R12 or R12 and R13 may bond together to form a 5- to 8-membered heterocyclic ring], etc.}, or a salt thereof.Type: ApplicationFiled: April 19, 2002Publication date: January 6, 2005Inventors: Shuichi Suzuki, Makoto Kotake, Mitsuaki Miyamoto, Tetsuya Kawahara, Akiharu Kajiwara, Ieharu Hishinuma, Kazuo Okano, Syuhei Miyazawa, Richard Clark, Fumihiro Ozaki, Nobuaki Sato, Masanobu Shinoda, Atsushi Kamada, Itaru Tsukada, Fumiyoshi Matsuura, Yoshimitsu Naoe, Taro Terauchi, Yoshiaki Oohashi, Osamu Ito, Hiroshi Tanaka, Takashi Musha, Motoji Kogushi, Tsutomu Kawata, Toshiyuki Matsuoka, Hiroko Kobayashi, Ken-ichi Chiba, Akifumi Kimura, Naoto Ono
-
Publication number: 20040242627Abstract: A 2-iminoimidazole derivative represented by the formula: 1Type: ApplicationFiled: June 11, 2004Publication date: December 2, 2004Inventors: Shuichi Suzuki, Makoto Kotake, Mitsuaki Miyamoto, Tetsuya Kawahara, Akiharu Kajiwara, Ieharu Hishinuma, Kazuo Okano, Syuhei Miyazawa, Richard Clark, Fumihiro Ozaki, Nobuaki Sato, Masanobu Shinoda, Atsushi Kamada, Itaru Tsukada, Fumiyoshi Matsuura, Yoshimitsu Naoe, Taro Terauchi, Yoshiaki Oohashi, Osamu Ito, Hiroshi Tanaka, Takashi Musha, Motoji Kogushi, Tsutomu Kawata, Toshiyuki Matsuoka, Hiroko Kobayashi, Ken-ichi Chiba, Akifumi Kimura, Naoto Ono
-
Publication number: 20040092737Abstract: Benzopiperidine derivatives represented by formula (I), salts thereof or hydrates thereof, processes for producing the same and drugs comprising the same: 1Type: ApplicationFiled: September 20, 2002Publication date: May 13, 2004Applicant: Eisai Co., Ltd.Inventors: Toshihiko Kaneko, Richard Clark, Norihito Ohi, Fumihiro Ozaki, Tetsuya Kawahara, Atsushi Kamada, Kazuo Okano, Hiromitsu Yokohama, Kenzo Muramoto, Tohru Arai, Masayoshi Ohkuro, Osamu Takenaka, Jiro Sonoda