Patents by Inventor Than Nguyen

Than Nguyen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200046493
    Abstract: A heart valve prosthesis is provided having a self-expanding multi-level frame that supports a valve body comprising a skirt and plurality of coapting leaflets. The frame transitions between a contracted delivery configuration that enables percutaneous transluminal delivery, and an expanded deployed configuration having an asymmetric hourglass shape. The valve body skirt and leaflets are constructed so that the center of coaptation may be selected to reduce horizontal forces applied to the commissures of the valve, and to efficiently distribute and transmit forces along the leaflets and to the frame. Alternatively, the valve body may be used as a surgically implantable replacement valve prosthesis.
    Type: Application
    Filed: October 14, 2019
    Publication date: February 13, 2020
    Inventors: Than Nguyen, Hung Nguyen, MyKim Nguyen, Stanley Komatsu, Robrecht Michiels
  • Patent number: 10478291
    Abstract: A heart valve prosthesis is provided having a self-expanding multi-level frame that supports a valve body comprising a skirt and plurality of coapting leaflets. The frame transitions between a contracted delivery configuration that enables percutaneous transluminal delivery, and an expanded deployed configuration having an asymmetric hourglass shape. The valve body skirt and leaflets are constructed so that the center of coaptation may be selected to reduce horizontal forces applied to the commissures of the valve, and to efficiently distribute and transmit forces along the leaflets and to the frame. Alternatively, the valve body may be used as a surgically implantable replacement valve prosthesis.
    Type: Grant
    Filed: October 17, 2016
    Date of Patent: November 19, 2019
    Assignee: Medtronic CV Luxembourg S.A.R.L
    Inventors: Than Nguyen, Hung Nguyen, MyKim Nguyen, Stanley Komatsu, Robrecht Michiels
  • Patent number: 10201716
    Abstract: Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways.
    Type: Grant
    Filed: December 30, 2010
    Date of Patent: February 12, 2019
    Assignee: CIANNA MEDICAL, INC.
    Inventors: George D. Hermann, Eduardo Chi Sing, Gail S. Lebovic, Mark A. Cole, Mark A. Ritchart, Than Nguyen
  • Publication number: 20190022410
    Abstract: Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways.
    Type: Application
    Filed: July 30, 2018
    Publication date: January 24, 2019
    Inventors: George D. Hermann, Eduardo Chi Sing, Gail S. Lebovic, Mark A. Cole, Mark A. Ritchart, Than Nguyen
  • Publication number: 20170273785
    Abstract: A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable prosthesis frame. If desired, one or more expandable anchors may be used. The prosthesis frame, which entirely supports the valve annulus, valve leaflets, and valve commissure points, is configured to be collapsible for transluminal delivery and expandable to contact the anatomical annulus of the native valve when the assembly is properly positioned. Portions of the prosthesis frame may expand to a preset diameter to maintain coaptivity of the replacement valve and to prevent occlusion of the coronary ostia. The prosthesis frame is compressible about a catheter, and restrained from expanding by an outer sheath. The catheter may be inserted inside a lumen within the body, such as the femoral artery, and delivered to a desired location, such as the heart.
    Type: Application
    Filed: April 6, 2017
    Publication date: September 28, 2017
    Inventors: Jacques Seguin, Georg Bortlein, Than Nguyen, Edward Pannek
  • Patent number: 9585754
    Abstract: Implants formed by a helically wound wire and methods of using same for the treatment of a mitral heart valve. According to the invention, it has dimensions such that it is able to be screwed into the wall of the annulus and/or into the cardiac wall adjoining the annulus such that a portion of the annulus and/or of the wall is located in the perimeter of the implant; and it comprises at least one first coil able, during said screwing of the implant, to insert itself into the wall while having a first dimension and at least one second coil having a second dimension, or adopting this second dimension after implantation, the second dimension being smaller than the first dimension such that the implant, once inserted, enables contraction of the wall portion located in the perimeter of the implant.
    Type: Grant
    Filed: December 17, 2015
    Date of Patent: March 7, 2017
    Assignee: Medtronic, Inc.
    Inventors: Jacques Seguin, Than Nguyen, Bruno Lecointe
  • Publication number: 20170035563
    Abstract: A heart valve prosthesis is provided having a self-expanding multi-level frame that supports a valve body comprising a skirt and plurality of coapting leaflets. The frame transitions between a contracted delivery configuration that enables percutaneous transluminal delivery, and an expanded deployed configuration having an asymmetric hourglass shape. The valve body skirt and leaflets are constructed so that the center of coaptation may be selected to reduce horizontal forces applied to the commissures of the valve, and to efficiently distribute and transmit forces along the leaflets and to the frame. Alternatively, the valve body may be used as a surgically implantable replacement valve prosthesis.
    Type: Application
    Filed: October 17, 2016
    Publication date: February 9, 2017
    Inventors: Than Nguyen, Hung Nguyen, MyKim Nguyen, Stanley Komatsu, Robrecht Michiels
  • Patent number: 9517131
    Abstract: A cardiac valve repair device has a membrane assembly and a frame. The frame has a central structure that defines a central separation, a pair of sleeves positioned below the central structure, and a pair of atrial alignment expansion beams. Each atrial alignment expansion beam has a curved section and inner section at each opposite end that defines a scissor-crossing where they overlap each other to form a separate lower expansion clip beam at each of the opposite ends thereof. The cardiac valve repair device also includes a pair of upper expansion clip beams. A V-shaped ventricular expansion curved beam extends below the two sleeves, with the membrane assembly secured to the V-shaped ventricular expansion curved beam. A pair of ventricular alignment stabilizing beams extends downwardly from the two sleeves.
    Type: Grant
    Filed: May 28, 2015
    Date of Patent: December 13, 2016
    Inventor: Than Nguyen
  • Patent number: 9504564
    Abstract: A heart valve prosthesis is provided having a self-expanding multi-level frame that supports a valve body comprising a skirt and plurality of coapting leaflets. The frame transitions between a contracted delivery configuration that enables percutaneous transluminal delivery, and an expanded deployed configuration having an asymmetric hourglass shape. The valve body skirt and leaflets are constructed so that the center of coaptation may be selected to reduce horizontal forces applied to the commissures of the valve, and to efficiently distribute and transmit forces along the leaflets and to the frame. Alternatively, the valve body may be used as a surgically implantable replacement valve prosthesis.
    Type: Grant
    Filed: May 12, 2006
    Date of Patent: November 29, 2016
    Assignee: Medtronic Corevalve LLC
    Inventors: Than Nguyen, Hung Nguyen, MyKim Nguyen, Stanley Komatsu, Robrecht Michiels
  • Publication number: 20160166382
    Abstract: A cardiac valve repair device has a membrane assembly and a frame. The frame has a central structure that defines a central separation, a pair of sleeves positioned below the central structure, and a pair of atrial alignment expansion beams. Each atrial alignment expansion beam has a curved section and inner section at each opposite end that defines a scissor-crossing where they overlap each other to form a separate lower expansion clip beam at each of the opposite ends thereof. The cardiac valve repair device also includes a pair of upper expansion clip beams. A V-shaped ventricular expansion curved beam extends below the two sleeves, with the membrane assembly secured to the V-shaped ventricular expansion curved beam. A pair of ventricular alignment stabilizing beams extends downwardly from the two sleeves.
    Type: Application
    Filed: May 28, 2015
    Publication date: June 16, 2016
    Inventor: Than Nguyen
  • Publication number: 20160166380
    Abstract: Implants formed by a helically wound wire and methods of using same for the treatment of a mitral heart valve. According to the invention, it has dimensions such that it is able to be screwed into the wall of the annulus and/or into the cardiac wall adjoining the annulus such that a portion of the annulus and/or of the wall is located in the perimeter of the implant; and it comprises at least one first coil able, during said screwing of the implant, to insert itself into the wall while having a first dimension and at least one second coil having a second dimension, or adopting this second dimension after implantation, the second dimension being smaller than the first dimension such that the implant, once inserted, enables contraction of the wall portion located in the perimeter of the implant.
    Type: Application
    Filed: December 17, 2015
    Publication date: June 16, 2016
    Inventors: Jacques Seguin, Than Nguyen, Bruno Lecointe
  • Patent number: 9295550
    Abstract: Methods for delivering a prosthetic heart valve include advancing a delivery catheter containing the prosthetic heart valve to a deployment native heart valve, advancing an inner core movably coupled to a restraining sheath of the delivery catheter to expose a first end of the prosthetic heart valve, and advancing the inner core and the restraining to expose a second end of the prosthetic heart valve. The delivery catheter can include a distal flange located at a distal end of an outer core of the catheter body, configured to restrict distal longitudinal displacement of the prosthetic heart valve, and a retaining structure located proximally from the distal flange along the outer core of the catheter body, configured to restrict proximal longitudinal displacement of the prosthetic heart valve.
    Type: Grant
    Filed: March 28, 2014
    Date of Patent: March 29, 2016
    Assignee: Medtronic CV Luxembourg S.a.r.l.
    Inventors: Than Nguyen, Jacques Seguin, Stan Komatsu, Hung Nguyen, Georg Boertlein
  • Patent number: 9237886
    Abstract: This implant (1) is formed by a helically wound wire (2). According to the invention, it has dimensions such that it is able to be screwed into the wall of the annulus (103) and/or into the cardiac wall (101) adjoining this annulus (103) such that a portion of said annulus (103) and/or of said wall (101) is located in the perimeter of the implant (1); and it comprises at least one first coil able, during said screwing of the implant (1), to insert itself into said wall while having a first dimension and at least one second coil having a second dimension, or adopting this second dimension after implantation, said second dimension being smaller than the first dimension such that the implant (1), once inserted, enables contraction of said wall portion located in the perimeter of this implant (1).
    Type: Grant
    Filed: April 14, 2008
    Date of Patent: January 19, 2016
    Assignee: Medtronic, Inc.
    Inventors: Jacques Seguin, Than Nguyen, Bruno Lecointe
  • Patent number: 9060857
    Abstract: A heart valve prosthesis is provided having a self-expanding multi-level frame that supports a valve body comprising a skirt and plurality of coapting leaflets. The frame transitions between a contracted delivery configuration that enables percutaneous transluminal delivery, and an expanded deployed configuration having an asymmetric hourglass shape. The valve body skirt and leaflets are constructed so that the center of coaptation may be selected to reduce horizontal forces applied to the commissures of the valve, and to efficiently distribute and transmit forces along the leaflets and to the frame. Alternatively, the valve body may be used as a surgically implantable replacement valve prosthesis.
    Type: Grant
    Filed: June 19, 2012
    Date of Patent: June 23, 2015
    Assignee: Medtronic CoreValve LLC
    Inventors: Than Nguyen, Hung Nguyen, Mykim Nguyen, Stanley Komatsu, Robrecht Michiels
  • Publication number: 20150127095
    Abstract: A heart valve prosthesis is provided having a self-expanding multi-level frame that supports a valve body comprising a skirt and plurality of coapting leaflets. The frame transitions between a contracted delivery configuration that enables percutaneous transluminal delivery, and an expanded deployed configuration having an asymmetric hourglass shape. The valve body skirt and leaflets are constructed so that the center of coaptation may be selected to reduce horizontal forces applied to the commissures of the valve, and to efficiently distribute and transmit forces along the leaflets and to the frame. Alternatively, the valve body may be used as a surgically implantable replacement valve prosthesis.
    Type: Application
    Filed: June 19, 2012
    Publication date: May 7, 2015
    Applicant: Medtronic Corevalve, Inc.
    Inventors: Than Nguyen, Hung Nguyen, Mykim Nguyen, Stanley Komatsu, Robrecht Michiels
  • Patent number: 8858415
    Abstract: Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways.
    Type: Grant
    Filed: April 21, 2010
    Date of Patent: October 14, 2014
    Assignee: Cianna Medical, Inc.
    Inventors: Eduardo Chi Sing, George D. Hermann, Mark A. Cole, Mark A. Richart, Than Nguyen, Gail S. Lebovic
  • Publication number: 20140214154
    Abstract: Methods for delivering a prosthetic heart valve include advancing a delivery catheter containing the prosthetic heart valve to a deployment location at a native heart valve, advancing an inner core movably coupled to a restraining sheath of the delivery catheter to expose a first end of the prosthetic heart valve, and advancing the inner core and the restraining sheath to expose a second end of the prosthetic heart valve. The delivery catheter can include a distal flange located at a distal end of an outer core of the catheter body, configured to restrict distal longitudinal displacement of the prosthetic heart valve, and a retaining structure located proximally from the distal flange along the outer core of the catheter body, configured to restrict proximal longitudinal displacement of the prosthetic heart valve.
    Type: Application
    Filed: March 28, 2014
    Publication date: July 31, 2014
    Applicant: Medtronic CoreValve LLC
    Inventors: Than Nguyen, Jacques Seguin, Stan Komatsu, Hung Nguyen, Georg Boertlein
  • Patent number: 8747459
    Abstract: A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable prosthesis frame. The valve may be delivered transluminally or transmyocardially using a thorascopic or other limited access approach using a delivery catheter. Preferably, the initial partial expansion of the valve is performed against the native valve annulus to provide adequate anchoring and positioning of the valve as the remaining portions of the valve expand. The valve may be delivered using a retrograde or antegrade approach. When delivered using a retrograde approach, a delivery catheter with a pull-back sheath may be used, while antegrade delivery is preferably performed with a delivery catheter with a push-forward sheath that releases the proximal end of the valve first.
    Type: Grant
    Filed: December 6, 2007
    Date of Patent: June 10, 2014
    Assignee: Medtronic CoreValve LLC
    Inventors: Than Nguyen, Jacques Seguin, Stan Komatsu, Hung Nguyen, Georg Boertlein
  • Patent number: D732666
    Type: Grant
    Filed: August 9, 2011
    Date of Patent: June 23, 2015
    Assignee: Medtronic Corevalve, Inc.
    Inventors: Than Nguyen, Hung Nguyen, Mykim Nguyen, Stanley Komatsu, Robrecht Michiels
  • Patent number: D812226
    Type: Grant
    Filed: June 19, 2015
    Date of Patent: March 6, 2018
    Assignee: Medtronic CoreValve LLC
    Inventors: Than Nguyen, Hung Nguyen, Mykim Nguyen, Stanley Komatsu, Robert Michiels