Patents by Inventor Than Nguyen
Than Nguyen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20150127095Abstract: A heart valve prosthesis is provided having a self-expanding multi-level frame that supports a valve body comprising a skirt and plurality of coapting leaflets. The frame transitions between a contracted delivery configuration that enables percutaneous transluminal delivery, and an expanded deployed configuration having an asymmetric hourglass shape. The valve body skirt and leaflets are constructed so that the center of coaptation may be selected to reduce horizontal forces applied to the commissures of the valve, and to efficiently distribute and transmit forces along the leaflets and to the frame. Alternatively, the valve body may be used as a surgically implantable replacement valve prosthesis.Type: ApplicationFiled: June 19, 2012Publication date: May 7, 2015Applicant: Medtronic Corevalve, Inc.Inventors: Than Nguyen, Hung Nguyen, Mykim Nguyen, Stanley Komatsu, Robrecht Michiels
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Patent number: 8858415Abstract: Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways.Type: GrantFiled: April 21, 2010Date of Patent: October 14, 2014Assignee: Cianna Medical, Inc.Inventors: Eduardo Chi Sing, George D. Hermann, Mark A. Cole, Mark A. Richart, Than Nguyen, Gail S. Lebovic
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Publication number: 20140214154Abstract: Methods for delivering a prosthetic heart valve include advancing a delivery catheter containing the prosthetic heart valve to a deployment location at a native heart valve, advancing an inner core movably coupled to a restraining sheath of the delivery catheter to expose a first end of the prosthetic heart valve, and advancing the inner core and the restraining sheath to expose a second end of the prosthetic heart valve. The delivery catheter can include a distal flange located at a distal end of an outer core of the catheter body, configured to restrict distal longitudinal displacement of the prosthetic heart valve, and a retaining structure located proximally from the distal flange along the outer core of the catheter body, configured to restrict proximal longitudinal displacement of the prosthetic heart valve.Type: ApplicationFiled: March 28, 2014Publication date: July 31, 2014Applicant: Medtronic CoreValve LLCInventors: Than Nguyen, Jacques Seguin, Stan Komatsu, Hung Nguyen, Georg Boertlein
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Patent number: 8747459Abstract: A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable prosthesis frame. The valve may be delivered transluminally or transmyocardially using a thorascopic or other limited access approach using a delivery catheter. Preferably, the initial partial expansion of the valve is performed against the native valve annulus to provide adequate anchoring and positioning of the valve as the remaining portions of the valve expand. The valve may be delivered using a retrograde or antegrade approach. When delivered using a retrograde approach, a delivery catheter with a pull-back sheath may be used, while antegrade delivery is preferably performed with a delivery catheter with a push-forward sheath that releases the proximal end of the valve first.Type: GrantFiled: December 6, 2007Date of Patent: June 10, 2014Assignee: Medtronic CoreValve LLCInventors: Than Nguyen, Jacques Seguin, Stan Komatsu, Hung Nguyen, Georg Boertlein
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Patent number: 8517907Abstract: Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways.Type: GrantFiled: November 24, 2008Date of Patent: August 27, 2013Assignee: Cianna Medical, Inc.Inventors: Eduardo Chi Sing, Tommy G. Nguyen, George D. Hermann, Than Nguyen, Doug S. Sutton
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Patent number: 8518108Abstract: Prosthetic heart valve suture rings having a suturable annulus of a compliant internal member and a cloth covering. Three evenly spaced upwardly opening depressions formed on an internal circumference of the suturable annulus receive downwardly-directed cusps of a stent structure of the heart valve. The suture ring may include a silicone sponge waffle annulus having a walled lip on an inner circumference thereof. The lip is contoured to include the three depressions, and a ring washer mounts on the annulus surrounding the walled lip for added stiffness.Type: GrantFiled: August 12, 2005Date of Patent: August 27, 2013Assignee: Edwards Lifesciences CorporationInventors: Van Le Huynh, Than Nguyen, Hung Ly Lam, Xiaoming G. Guo, Ralph Kafesjian
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Publication number: 20120259409Abstract: A heart valve prosthesis is provided having a self-expanding multi-level frame that supports a valve body comprising a skirt and plurality of coapting leaflets. The frame transitions between a contracted delivery configuration that enables percutaneous transluminal delivery, and an expanded deployed configuration having an asymmetric hourglass shape. The valve body skirt and leaflets are constructed so that the center of coaptation may be selected to reduce horizontal forces applied to the commissures of the valve, and to efficiently distribute and transmit forces along the leaflets and to the frame. Alternatively, the valve body may be used as a surgically implantable replacement valve prosthesis.Type: ApplicationFiled: June 19, 2012Publication date: October 11, 2012Applicant: Medtronic Corevalve, Inc.Inventors: Than Nguyen, Hung Nguyen, Mykim Nguyen, Stanley Komatsu, Robrecht Michiels
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Patent number: 8226710Abstract: A heart valve prosthesis is provided having a self-expanding multi-level frame that supports a valve body comprising a skirt and plurality of coapting leaflets. The frame transitions between a contracted delivery configuration that enables percutaneous transluminal delivery, and an expanded deployed configuration having an asymmetric hourglass shape. The valve body skirt and leaflets are constructed so that the center of coaptation may be selected to reduce horizontal forces applied to the commissures of the valve, and to efficiently distribute and transmit forces along the leaflets and to the frame. Alternatively, the valve body may be used as a surgically implantable replacement valve prosthesis.Type: GrantFiled: March 25, 2011Date of Patent: July 24, 2012Assignee: Medtronic Corevalve, Inc.Inventors: Than Nguyen, Hung Nguyen, Mykim Nguyen, Stanley Komatsu, Robrecht Michiels
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Publication number: 20110172765Abstract: A heart valve prosthesis is provided having a self-expanding multi-level frame that supports a valve body comprising a skirt and plurality of coapting leaflets. The frame transitions between a contracted delivery configuration that enables percutaneous transluminal delivery, and an expanded deployed configuration having an asymmetric hourglass shape. The valve body skirt and leaflets are constructed so that the center of coaptation may be selected to reduce horizontal forces applied to the commissures of the valve, and to efficiently distribute and transmit forces along the leaflets and to the frame. Alternatively, the valve body may be used as a surgically implantable replacement valve prosthesis.Type: ApplicationFiled: March 25, 2011Publication date: July 14, 2011Applicant: Medtronic CoreValve LLCInventors: Than Nguyen, Hung Nguyen, Mykim Nguyen, Stanley Komatsu, Robrecht Michiels
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Publication number: 20110137103Abstract: Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways.Type: ApplicationFiled: December 30, 2010Publication date: June 9, 2011Inventors: George D. Hermann, Eduardo Chi Sing, Gail S. Lebovic, Mark A. Cole, Mark A. Ritchart, Than Nguyen
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Patent number: 7914569Abstract: A heart valve prosthesis is provided having a self-expanding multi-level frame that supports a valve body comprising a skirt and plurality of coapting leaflets. The frame transitions between a contracted delivery configuration that enables percutaneous transluminal delivery, and an expanded deployed configuration having an asymmetric hourglass shape. The valve body skirt and leaflets are constructed so that the center of coaptation may be selected to reduce horizontal forces applied to the commissures of the valve, and to efficiently distribute and transmit forces along the leaflets and to the frame. Alternatively, the valve body may be used as a surgically implantable replacement valve prosthesis.Type: GrantFiled: May 13, 2005Date of Patent: March 29, 2011Assignee: Medtronics CoreValve LLCInventors: Than Nguyen, Hung Nguyen, Mykim Nguyen, Stanley Komatsu, Robrecht Michiels
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Patent number: 7862498Abstract: Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways. The apparatus may include features to prevent overexpansion of the elongate members and/or to facilitate rapid collapse of the elongate members.Type: GrantFiled: October 6, 2007Date of Patent: January 4, 2011Assignee: Cianna Medical, Inc.Inventors: Tommy G. Nguyen, Than Nguyen, Doug S. Sutton
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Patent number: 7862496Abstract: Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways.Type: GrantFiled: March 16, 2006Date of Patent: January 4, 2011Assignee: Cianna Medical, Inc.Inventors: George D. Hermann, Eduardo Chi Sing, Gail S. Lebovic, Mark A. Cole, Mark A. Ritchart, Than Nguyen
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Publication number: 20100292785Abstract: This implant (1) is formed by a helically wound wire (2). According to the invention, it has dimensions such that it is able to be screwed into the wall of the annulus (103) and/or into the cardiac wall (101) adjoining this annulus (103) such that a portion of said annulus (103) and/or of said wall (101) is located in the perimeter of the implant (1); and it comprises at least one first coil able, during said screwing of the implant (1), to insert itself into said wall while having a first dimension and at least one second coil having a second dimension, or adopting this second dimension after implantation, said second dimension being smaller than the first dimension such that the implant (1), once inserted, enables contraction of said wall portion located in the perimeter of this implant (1).Type: ApplicationFiled: April 14, 2008Publication date: November 18, 2010Applicant: Medtronic Corevalve LLCInventors: Jacques Seguin, Than Nguyen, Bruno Lecointe
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Publication number: 20100204537Abstract: Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways.Type: ApplicationFiled: April 21, 2010Publication date: August 12, 2010Inventors: George D. Hermann, Eduardo Chi Sing, Gail S. Lebovic, Mark A. Cole, Mark A. Ritchart, Than Nguyen
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Publication number: 20090156882Abstract: Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways.Type: ApplicationFiled: November 24, 2008Publication date: June 18, 2009Applicant: CIANNA MEDICAL, INC.Inventors: Eduardo Chi Sing, Tommy G. Nguyen, George D. Hermann, Than Nguyen, Doug S. Sutton
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Publication number: 20080140189Abstract: A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable prosthesis frame. The valve may be delivered transluminally or transmyocardially using a thorascopic or other limited access approach using a delivery catheter. Preferably, the initial partial expansion of the valve is performed against the native valve annulus to provide adequate anchoring and positioning of the valve as the remaining portions of the valve expand. The valve may be delivered using a retrograde or antegrade approach. When delivered using a retrograde approach, a delivery catheter with a pull-back sheath may be used, while antegrade delivery is preferably performed with a delivery catheter with a push-forward sheath that releases the proximal end of the valve first.Type: ApplicationFiled: December 6, 2007Publication date: June 12, 2008Applicant: CoreValve, Inc.Inventors: Than Nguyen, Jacques Seguin, Stan Komatsu, Hung Nguyen, Georg Boertlein
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Publication number: 20080091055Abstract: Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways. The apparatus may include features to prevent overexpansion of the elongate members and/or to facilitate rapid collapse of the elongate members.Type: ApplicationFiled: October 6, 2007Publication date: April 17, 2008Applicant: Cianna Medical, Inc.Inventors: Tommy Nguyen, Than Nguyen, Doug Sutton, George Hermann, Luis Urquidi
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Publication number: 20070239271Abstract: A system for loading a replacement valve prosthesis onto a minimally invasive delivery system, such as a delivery catheter. The system may include one or more frustoconical housings which define a tapered surface. The prosthesis may be moved along the tapered surface to compress the prosthesis. Desirably, for compression of the valve portion of the prosthesis, the prosthesis is moved along the tapered surface in a direction wherein the inlet end of the valve leads an outlet end of the valve. After compression, the prosthesis may be loaded into the sheath of the delivery catheter. Methods of loading the replacement valve prosthesis are also disclosed.Type: ApplicationFiled: July 18, 2006Publication date: October 11, 2007Inventor: Than Nguyen
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Publication number: 20070106108Abstract: Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways.Type: ApplicationFiled: March 16, 2006Publication date: May 10, 2007Inventors: George Hermann, Eduardo Chi Sing, Gail Lebovic, Mark Cole, Mark Ritchart, Than Nguyen