Patents by Inventor Theodore I. Malinin

Theodore I. Malinin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190134268
    Abstract: The present invention discloses the method of preparation and use of soft tissue membranous structures into slip resistant membranes with regularly spaced surface projections on one side and concave depressions on the other side with perforations or without perforations which enhance vascular ingrowth and tissue incorporation.
    Type: Application
    Filed: November 6, 2017
    Publication date: May 9, 2019
    Inventor: Theodore I. Malinin
  • Patent number: 10143562
    Abstract: A particulate composition for stimulating nucleus pulposus regeneration has a particulate composition made of vertebral end-plates having an osseous component wherein the composition is milled, ground or particulized into particles from 10 to 1000 microns in size. At least a part of the composition can be non-demineralized or demineralized or a mixture of demineralized and non-demineralized particles from the vertebral end-plates. Preferably, the non-demineralized part is not subjected to harsh chemical treating. To possibly enhance the release of growth factors and other similar substances from the osseous layer of the end-plate, the material may be treated with hydrochloric acid, ethylene diamine or other demineralizing agents or regimens.
    Type: Grant
    Filed: May 21, 2015
    Date of Patent: December 4, 2018
    Assignee: Vivex Biomedical, Inc.
    Inventor: Theodore I. Malinin
  • Publication number: 20180264148
    Abstract: The invention is a novel method of sterilizing bone and soft tissues intended for human transplantation. In one embodiment the process includes steps of subjecting transplants to high hydrostatic pressures of aqueous fluid to which chlorhexidine gluconate or similar sterilizing chemicals have been added.
    Type: Application
    Filed: May 24, 2018
    Publication date: September 20, 2018
    Applicant: Vivex Biomedical, Inc.
    Inventor: Theodore I. Malinin
  • Patent number: 10004819
    Abstract: The invention is a novel method of sterilizing bone and soft tissues intended for human transplantation. In one embodiment the process includes steps of subjecting transplants to high hydrostatic pressures of aqueous fluid to which chlorhexidine gluconate or similar sterilizing chemicals have been added.
    Type: Grant
    Filed: June 10, 2014
    Date of Patent: June 26, 2018
    Assignee: Vivex Biomedical, Inc.
    Inventor: Theodore I Malinin
  • Patent number: 9814502
    Abstract: A bone plate assembly has the screws on one plate, either distal or proximal to the fracture, placed through round holes perpendicular to long axis of a first bone thus securing the plate rigidly to the bone on one side relative to the fracture. The screw holes can be either threaded on non-threaded. On the other side of the fracture, the bone fragment is first secured with an inclined screw placed from less than 90 to 10 degrees towards the fracture. As the screw is tightened it advances away from the fracture pulling the first bone, securely attached, plate towards the fracture site and thus compressing the fracture.
    Type: Grant
    Filed: August 21, 2014
    Date of Patent: November 14, 2017
    Inventor: Theodore I Malinin
  • Patent number: 9737590
    Abstract: The present invention is a composition of a self-assembly of collagen fibers made from a plurality of sized pieces of a source material. The source material made from animal or human tissue selected from one of dermis, tendon, fascia or dura mater. The self-assembly occurring by induction of a magnetic field in a liquid medium.
    Type: Grant
    Filed: July 31, 2013
    Date of Patent: August 22, 2017
    Assignee: Vivex Biomedical, Inc.
    Inventor: Theodore I. Malinin
  • Publication number: 20160338844
    Abstract: A particulate composition for stimulating nucleus pulposus regeneration has a particulate composition made of vertebral end-plates having an osseous component wherein the composition is milled, ground or particulized into particles from 10 to 1000 microns in size. At least a part of the composition can be non-demineralized or demineralized or a mixture of demineralized and non-demineralized particles from the vertebral end-plates. Preferably, the non-demineralized part is not subjected to harsh chemical treating. To possibly enhance the release of growth factors and other similar substances from the osseous layer of the end-plate, the material may be treated with hydrochloric acid, ethylene diamine or other demineralizing agents or regimens.
    Type: Application
    Filed: May 21, 2015
    Publication date: November 24, 2016
    Applicant: VIVEX BIOMEDICAL, INC.
    Inventor: Theodore I. Malinin
  • Publication number: 20160326493
    Abstract: The present invention discloses recovery and isolation of mesenchymal stem cells from the peripheral blood. This has an advantage of being able to obtain multilineage inducible cells from readily obtainable and autologous allogenic blood. With the present invention it is no longer necessary to depend on cadaver donor bone marrow, a technically complicated and an expensive process. Instead the patient may obtain the needed stem cells from a relatively small amount of his/her own blood, or from readily available blood donors.
    Type: Application
    Filed: May 7, 2015
    Publication date: November 10, 2016
    Applicant: Vivex Biomedical, Inc.
    Inventors: Theodore I. Malinin, Dorothy R. Malinin, Wendy W. Weston
  • Patent number: 9433702
    Abstract: Cartilage materials such as cartilage fluff and a cartilage composition comprising a particulate material are disclosed. These are suitable for stimulating chondrogenesis and/or producing cartilage regeneration. Also disclosed are processes for their preparation. Methods for regenerating articular cartilage are also disclosed, which involve, for example, placing the cartilage fluff or cartilage composition into a cartilage defect.
    Type: Grant
    Filed: January 14, 2011
    Date of Patent: September 6, 2016
    Assignee: Vivex Biomedical, Inc.
    Inventor: Theodore I. Malinin
  • Patent number: 9402869
    Abstract: A treated composition of neural tissue is made of spinal cord tissue harvested from a spinal cord of a mammal. The spinal cord tissue is harvested from vertebral column of the mammal. The spinal cord tissue is harvested post mortem. The mammal is one of a primate, an equine, a bovine, a porcine or other mammalian animal. The spinal cord tissue is dried or has the water content in the tissue reduced or eliminated by freeze drying or hypothermic dehydration and treated with a cryopreservative.
    Type: Grant
    Filed: April 6, 2015
    Date of Patent: August 2, 2016
    Assignee: Vivex Biomedical, Inc.
    Inventors: Timothy Ganey, Theodore I. Malinin, Wendy W. Weston
  • Patent number: 9314330
    Abstract: Cruciate ligament substitutes are formed using fan-folded iliotibial band grafts of fascia lata. Devices of making the same and methods of making and using the same are described herein. The thick fan-folded grafts of fascia lata cruciate ligament substitutes disclosed herein are used in a single-loop fashion and have surprisingly exhibited load to failure and stiffness values that compare favorably with conventional grafts, including tibialis anterior, tibialis posterior, peroneus longus, and bone-patellar tendon-bone (BPTB) half-patella specimens, when the harvested iliotibial band grafts of fascia lata avoid portions thicker than 5 mm, or even 3 mm.
    Type: Grant
    Filed: January 10, 2011
    Date of Patent: April 19, 2016
    Assignee: Vivex Biomedical, Inc.
    Inventors: H. Thomas Temple, Theodore I. Malinin, Siu Tung Wu
  • Publication number: 20160051298
    Abstract: A bone plate assembly has the screws on one plate, either distal or proximal to the fracture, placed through round holes perpendicular to long axis of a first bone thus securing the plate rigidly to the bone on one side relative to the fracture. The screw holes can be either threaded on non-threaded. On the other side of the fracture, the bone fragment is first secured with an inclined screw placed from less than 90 to 10 degrees towards the fracture. As the screw is tightened it advances away from the fracture pulling the first bone, securely attached, plate towards the fracture site and thus compressing the fracture.
    Type: Application
    Filed: August 21, 2014
    Publication date: February 25, 2016
    Applicant: VALERIS MEDICAL, LLC
    Inventor: Theodore I. Malinin
  • Publication number: 20150352235
    Abstract: The invention is a novel method of sterilizing bone and soft tissues intended for human transplantation. In one embodiment the process includes steps of subjecting transplants to high hydrostatic pressures of aqueous fluid to which chlorhexidine gluconate or similar sterilizing chemicals have been added.
    Type: Application
    Filed: June 10, 2014
    Publication date: December 10, 2015
    Applicant: VIVEX BIOMEDICAL INC.
    Inventor: Theodore I. Malinin
  • Publication number: 20150344847
    Abstract: A method for production of large numbers of cartilage cells with phenotype retention intended for treatment of articular cartilage lesions or preparing viable cartilage tissue by propagation of chondrocytes from cartilage explants, human or animal, with the retention of phenotypes of the cartilage cells, in which cells are chondrocytes retaining morphologic attributes of the same or chondrocyte progenitor cells. The method includes culturing the cells in which cultured cells are organized into mature hyaline cartilage on the surface of biologic structures such as cancellous or cortical bone lamina. The method for culturing chondrocytes to produce three dimensional cellular structures consisting of cartilage cells and cell produced extracellular cartilage matrix.
    Type: Application
    Filed: May 29, 2014
    Publication date: December 3, 2015
    Applicant: VIVEX BIOMEDICAL INC.
    Inventor: Theodore I Malinin
  • Publication number: 20150258243
    Abstract: Particulate bone and structural bone, more specifically decalcified bone from endosteum having osteoinductive capacity and methods for their isolation and production are provided, more specifically, decalcified bone preparations derived from endosteal layer of bone are provided. Compositions formulated with material from endosteal layer of bone are provided along with preparation and methods of using decalcified endosteal compositions are disclosed. Endosteum is avascular and areolar in distinction to bone marrow which fills the canal. Because of its structure and anatomic position, endosteum is difficult to isolate and recognize, and therefore not regarded as an important constituent of allograft materials. One embodiment of the present invention allows for recognition and isolation of endosteum.
    Type: Application
    Filed: April 28, 2015
    Publication date: September 17, 2015
    Applicant: VIVEX BIOMEDICAL INC.
    Inventor: Theodore I Malinin
  • Publication number: 20150140096
    Abstract: Particulate bone and structural bone, more specifically decalcified bone from endosteum having osteoinductive capacity and methods for their isolation and production are provided, more specifically, decalcified bone preparations derived from endosteal layer of bone are provided. Compositions formulated with material from endosteal layer of bone are provided along with preparation and methods of using decalcified endosteal compositions are disclosed. Endosteum is avascular and areolar in distinction to bone marrow which fills the canal. Because of its structure and anatomic position, endosteum is difficult to isolate and recognize, and therefore not regarded as an important constituent of allograft materials. One embodiment of the present invention allows for recognition and isolation of endosteum.
    Type: Application
    Filed: March 12, 2014
    Publication date: May 21, 2015
    Applicant: VIVEX BIOMEDICAL INC.
    Inventor: Theodore I. Malinin
  • Publication number: 20150037432
    Abstract: The present invention is a composition of a self-assembly of collagen fibers made from a plurality of sized pieces of a source material. The source material made from animal or human tissue selected from one of dermis, tendon, fascia or dura mater. The self-assembly occurring by induction of a magnetic field in a liquid medium.
    Type: Application
    Filed: July 31, 2013
    Publication date: February 5, 2015
    Applicant: VIVEX BIOMEDICAL INC.
    Inventor: Theodore I. Malinin
  • Patent number: 8940698
    Abstract: Cartilage materials such as cartilage fluff and a cartilage composition comprising a particulate material are disclosed. These are suitable for stimulating chondrogenesis and/or producing cartilage regeneration. Also disclosed are processes for their preparation. Methods for regenerating articular cartilage are also disclosed, which involve, for example, placing the cartilage fluff or cartilage composition into a cartilage defect.
    Type: Grant
    Filed: August 14, 2013
    Date of Patent: January 27, 2015
    Assignee: Vivex Biomedical, Inc.
    Inventor: Theodore I. Malinin
  • Patent number: 8940692
    Abstract: Cartilage materials such as cartilage fluff and a cartilage composition comprising a particulate material are disclosed. These are suitable for stimulating chondrogenesis and/or producing cartilage regeneration. Also disclosed are processes for their preparation. Methods for regenerating articular cartilage are also disclosed, which involve, for example, placing the cartilage fluff or cartilage composition into a cartilage defect.
    Type: Grant
    Filed: June 5, 2014
    Date of Patent: January 27, 2015
    Assignee: Vivex Biomedical, Inc.
    Inventor: Theodore I. Malinin
  • Patent number: 8916339
    Abstract: A composition of neural tissue is made of spinal cord tissue harvested from a spinal cord of a mammal. The spinal cord tissue is harvested from vertebral column of the mammal. The spinal cord tissue is harvested post mortem. The mammal is one of a primate, an equine, a bovine, a porcine or other mammalian animal. The spinal cord tissue is dried or has the water content in the tissue reduced or eliminated by freeze drying or hypothermic dehydration.
    Type: Grant
    Filed: March 7, 2014
    Date of Patent: December 23, 2014
    Assignee: Vivex Biomedical, Inc.
    Inventor: Theodore I. Malinin