Patents by Inventor Theodore I. Malinin
Theodore I. Malinin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8916339Abstract: A composition of neural tissue is made of spinal cord tissue harvested from a spinal cord of a mammal. The spinal cord tissue is harvested from vertebral column of the mammal. The spinal cord tissue is harvested post mortem. The mammal is one of a primate, an equine, a bovine, a porcine or other mammalian animal. The spinal cord tissue is dried or has the water content in the tissue reduced or eliminated by freeze drying or hypothermic dehydration.Type: GrantFiled: March 7, 2014Date of Patent: December 23, 2014Assignee: Vivex Biomedical, Inc.Inventor: Theodore I. Malinin
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Patent number: 8882774Abstract: Procedures and instruments for preparing and transplanting osteochondral allograft plugs to a host bone to repair an articular cartilage defect. An allograft bone plug having a cartilage plate and cancellous bone tissue attached thereto is removed from a donor bone. The allograft plug is further shaped by removing or cutting away cancellous bone tissue to form a cancellous stalk extending from the cartilage plate. At the recipient site of the host bone, a cutout is formed corresponding in shape to the allograft plug. The allograft plug is inserted into the cutout such that the cancellous stalk is retained in the host bone and the cartilage plate aligns with the condyle surface of the host bone.Type: GrantFiled: February 21, 2007Date of Patent: November 11, 2014Assignee: Biomet Sports Medicine, LLCInventor: Theodore I. Malinin
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Publication number: 20140294911Abstract: Cartilage materials such as cartilage fluff and a cartilage composition comprising a particulate material are disclosed. These are suitable for stimulating chondrogenesis and/or producing cartilage regeneration. Also disclosed are processes for their preparation. Methods for regenerating articular cartilage are also disclosed, which involve, for example, placing the cartilage fluff or cartilage composition into a cartilage defect.Type: ApplicationFiled: June 5, 2014Publication date: October 2, 2014Applicant: Vivex Biomedical Inc.Inventor: Theodore I. Malinin
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Publication number: 20140220096Abstract: Cartilage materials such as cartilage fluff and a cartilage composition comprising a particulate material are disclosed. These are suitable for stimulating chondrogenesis and/or producing cartilage regeneration. Also disclosed are processes for their preparation. Methods for regenerating articular cartilage are also disclosed, which involve, for example, placing the cartilage fluff or cartilage composition into a cartilage defect.Type: ApplicationFiled: April 7, 2014Publication date: August 7, 2014Applicant: VIVEX BIOMEDICAL INC.Inventor: Theodore I. Malinin
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Patent number: 8791071Abstract: Cartilage materials such as cartilage fluff and a cartilage composition comprising a particulate material are disclosed. These are suitable for stimulating chondrogenesis and/or producing cartilage regeneration. Also disclosed are processes for their preparation. Methods for regenerating articular cartilage are also disclosed, which involve, for example, placing the cartilage fluff or cartilage composition into a cartilage defect.Type: GrantFiled: April 7, 2014Date of Patent: July 29, 2014Assignee: Vivex Biomedical, Inc.Inventor: Theodore I. Malinin
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Publication number: 20130330391Abstract: Cartilage materials such as cartilage fluff and a cartilage composition comprising a particulate material are disclosed. These are suitable for stimulating chondrogenesis and/or producing cartilage regeneration. Also disclosed are processes for their preparation. Methods for regenerating articular cartilage are also disclosed, which involve, for example, placing the cartilage fluff or cartilage composition into a cartilage defect.Type: ApplicationFiled: August 14, 2013Publication date: December 12, 2013Applicant: VIVEX BIOMEDICAL INC.Inventor: Theodore I. Malinin
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Patent number: 8523864Abstract: Provided are procedures and instruments for preparing and transplanting osteochondral allograft plugs to a host bone to repair an articular cartilage defect. An allograft bone plug having a cartilage plate and cancellous bone tissue attached thereto is removed from a donor bone. The allograft plug is further shaped by removing or cutting away cancellous bone tissue to form a cancellous stalk extending from the cartilage plate. The formed cancellous stalk can have any suitable shape including cylindrical, conical, and rectilinear. At the recipient site of the host bone, a cutout is formed corresponding in shape to the allograft plug. The allograft plug is inserted into the cutout such that the cancellous stalk is retained in the host bone and the cartilage plate aligns with the condyle surface of the host bone. Aspects of the invention may also be applicable to preparing and transplanting osteochondral autograft plugs.Type: GrantFiled: February 23, 2007Date of Patent: September 3, 2013Assignee: Biomet Sports Medicine, LLCInventor: Theodore I. Malinin
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Patent number: 8318212Abstract: Disclosed is a method for regenerating articular cartilage in an animal comprising administering a therapeutically effective amount of a non-demineralized particulate articular cartilage having a distribution of particle sizes within the range of from about 60 microns to about 500 microns.Type: GrantFiled: November 5, 2010Date of Patent: November 27, 2012Assignee: University of MiamiInventor: Theodore I. Malinin
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Publication number: 20120283829Abstract: Cruciate ligament substitutes are formed using fan-folded fascia lata grafts. Devices of making the same and methods of making and using the same are described herein. The fan-folded fascia lata cruciate ligament substitutes disclosed herein are used in a single-loop fashion and have surprisingly exhibited load to failure and stiffness values that compare favorably with conventional grafts, including tibialis anterior, tibialis posterior, peroneus longus, and bone-patellar tendon-bone (BPTB) half-patella specimens. It has been demonstrated that single-loop, fan-folded fascia lata sheets can exhibit mechanical properties that compare favorably with existing cruciate ligament grafts. An apparatus for handling a fascia lata sheet can include a first and a second removable anchoring member.Type: ApplicationFiled: January 10, 2011Publication date: November 8, 2012Inventors: H. Thomas Temple, Theodore I. Malinin, Siu Tung Wu
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Publication number: 20110104242Abstract: Cartilage materials such as cartilage fluff and a cartilage composition comprising a particulate material are disclosed. These are suitable for stimulating chondrogenesis and/or producing cartilage regeneration. Also disclosed are processes for their preparation. Methods for regenerating articular cartilage are also disclosed, which involve, for example, placing the cartilage fluff or cartilage composition into a cartilage defect.Type: ApplicationFiled: January 14, 2011Publication date: May 5, 2011Inventor: Theodore I. Malinin
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Publication number: 20110052705Abstract: Disclosed is a method for regenerating articular cartilage in an animal comprising administering a therapeutically effective amount of a non-demineralized particulate articular cartilage having a distribution of particle sizes within the range of from about 60 microns to about 500 microns.Type: ApplicationFiled: November 5, 2010Publication date: March 3, 2011Inventor: Theodore I. Malinin
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Publication number: 20110009967Abstract: An intervertebral implant for replacing a damage intervertebral disk within the spinal column can include a generally flat body having opposing surfaces. To promote bone growth and fusion of the adjacent vertebrae together, in an aspect, the implant can be provided with osteogenic or medicinal material received into one or more apertures disposed into the surfaces of the implant. To better retain the osteogenic material, the apertures can be disposed on a non-perpendicular angle with respect to the implant and/or can be tapered. In another aspect, the implant can include a plurality of grooves disposed across a surface to reduce slipping of the inserted implant between the adjacent vertebrae. In a further aspect, the implant can be formed by cutting a plurality of implants parallel along the diaphysis of a long bone. In another aspect, the implant can be generally as a bow or question mark.Type: ApplicationFiled: September 2, 2010Publication date: January 13, 2011Inventors: Theodore I. Malinin, H. Thomas Temple
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Publication number: 20100268339Abstract: An invertebral implant for replacing a damage invertebral disk within the spinal column can include a generally flat body having opposing surfaces and peripheral wall or surface that extends between the opposing surface. Protruding outwardly from the peripheral wall can be a shelf-like flange that has a reduced thickness compared to the thickness of the main body of the implant. The flange provides an object or structure that the surgeon can grasp with forceps during insertion between adjacent vertebrae. Because the protruding nature and reduced thickness of the flange, both the flange and the forceps placed thereon can fit within or adjacent to the intervertebral space between the adjacent vertebrae without interfering with orientation or placement of the main body between the vertebrae. Hence, the flange may simplify the surgical insertion procedure.Type: ApplicationFiled: June 25, 2010Publication date: October 21, 2010Inventors: Theodore I. Malinin, H. Thomas Temple
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Patent number: 7550007Abstract: Provided are procedures and instruments for preparing and transplanting osteochondral allograft plugs to a host bone to repair an articular cartilage defect. An allograft bone plug having a cartilage plate and cancellous bone tissue attached thereto is removed from a donor bone. The allograft plug is further shaped by removing or cutting away cancellous bone tissue to form a cancellous stalk extending from the cartilage plate. The formed cancellous stalk can have any suitable shape including cylindrical, conical, and rectilinear. At the recipient site of the host bone, a cutout is formed corresponding in shape to the allograft plug. The allograft plug is inserted into the cutout such that the cancellous stalk is retained in the host bone and the cartilage plate aligns with the condyle surface of the host bone. Aspects of the invention may also be applicable to preparing and transplanting osteochondral autograft plugs.Type: GrantFiled: February 23, 2007Date of Patent: June 23, 2009Assignee: Biomet Sports Medicine, LLCInventor: Theodore I. Malinin
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Publication number: 20090018659Abstract: An invertebral implant for replacing a damage invertebral disk within the spinal column can include a generally flat body having opposing surfaces. To promote bone growth and fusion of the adjacent vertebrae together, in an aspect, the implant can be provided with osteogenic or medicinal material received into one or more apertures disposed into the surfaces of the implant. To better retain the osteogenic material, the apertures can be disposed on a non-perpendicular angle with respect to the implant and/or can be tapered. In another aspect, the implant can include a plurality of grooves disposed across a surface to reduce slipping of the inserted implant between the adjacent vertebrae. In a further aspect, the implant can be formed by cutting a plurality of implants parallel along the diaphysis of a long bone. In another aspect, the implant can be generally as a bow or question mark.Type: ApplicationFiled: July 10, 2007Publication date: January 15, 2009Inventor: Theodore I. Malinin
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Publication number: 20080279825Abstract: Cartilage materials such as cartilage fluff and a cartilage composition comprising a particulate material are disclosed. These are suitable for stimulating chondrogenesis and/or producing cartilage regeneration. Also disclosed are processes for their preparation. Methods for regenerating articular cartilage are also disclosed, which involve, for example, placing the cartilage fluff or cartilage composition into a cartilage defect.Type: ApplicationFiled: May 10, 2007Publication date: November 13, 2008Inventor: Theodore I. Malinin
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Patent number: 7371260Abstract: Provided are procedures and instruments for preparing and transplanting osteochondral allograft plugs to a host bone to repair an articular cartilage defect. An allograft bone plug having a cartilage plate and cancellous bone tissue attached thereto is removed from a donor bone. The allograft plug is further shaped by removing or cutting away cancellous bone tissue to form a cancellous stalk extending from the cartilage plate. The formed cancellous stalk can have any suitable shape including cylindrical, conical, and rectilinear. At the recipient site of the host bone, a cutout is formed corresponding in shape to the allograft plug. The allograft plug is inserted into the cutout such that the cancellous stalk is retained in the host bone and the cartilage plate aligns with the condyle surface of the host bone. Aspects of the invention may also be applicable to preparing and transplanting osteochondral autograft plugs.Type: GrantFiled: October 26, 2005Date of Patent: May 13, 2008Assignee: Biomet Sports Medicine, Inc.Inventor: Theodore I. Malinin
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Patent number: 7335381Abstract: A particulate bone of defined sizes which has a unique property of direct bone osteoinduction without going through endochondral ossification stage is disclosed. The bone is not subjected to chemical extraction or decalcification. This allows for the retention of all physiologically active components of native bone. The invention hinges on the newly discovered ability of bone particles of defined sizes to exert osteoinduction by a pathway superior to and distinct from demineralized bone matrix and similar preparations.Type: GrantFiled: October 1, 2004Date of Patent: February 26, 2008Assignee: Losec, IncInventors: Theodore I. Malinin, H. Thomas Temple, Alvaro Flores, Billy E. Buck