Patents by Inventor Thierry Verpoort
Thierry Verpoort has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10058646Abstract: The present invention relates to a blood bag system, a method for its manufacture, and a process for reducing pathogens and leucocytes in biological fluids in particular in therapeutic quantities of platelet concentrates (PC) contained in the blood bag system, using UV-light and agitation, wherein part of the plasma of the PC is optionally exchanged against a platelet additive solution.Type: GrantFiled: March 6, 2017Date of Patent: August 28, 2018Assignee: MACO PHARMA S.A.Inventors: Wolfram Hubert Walker, Frank Tolksdorf, Thierry Verpoort, Francis Goudaliez
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Publication number: 20170232163Abstract: The present invention relates to a blood bag system, a method for its manufacture, and a process for reducing pathogens and leucocytes in biological fluids in particular in therapeutic quantities of platelet concentrates (PC) contained in the blood bag system, using UV-light and agitation, wherein part of the plasma of the PC is optionally exchanged against a platelet additive solution.Type: ApplicationFiled: March 6, 2017Publication date: August 17, 2017Applicant: MACO PHARMA S.A.Inventors: Wolfram Hubert Walker, Frank Tolksdorf, Thierry Verpoort, Francis Goudaliez
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Irradiation apparatus for inactivating pathogens and/or leukocytes in a biological fluid and process
Patent number: 9320817Abstract: The invention relates to an irradiation apparatus for inactivating pathogens and/or leukocytes in a biological fluid such as a platelet suspension and/or plasma comprising: a casing (2), a support member (3) for carrying at least one irradiation bag (19) containing the biological fluid, a light source (4) comprising two banks of light (5, 6) disposed above and below the support member (3), and an agitating system (25) for moving the support member (3), the light source generating UVC light of suitable intensity to inactivate pathogens and/or leukocytes and the agitation system moving the support member in an orbital path with predetermined amplitude and rotational frequency suitable to expose the whole biological fluid to UVC.Type: GrantFiled: July 11, 2014Date of Patent: April 26, 2016Assignee: MACO PHARMA S.A.Inventors: Wolfram Hubert Walker, Frank Tolksdorf, Thierry Verpoort, Francis Goudaliez, Maurice Behague, Arnaud Chavatte -
Patent number: 8986237Abstract: A filtering unit for removing a virucidal substance from a biological fluid including an outer casing having at least one input aperture and at least one output aperture. The outer casing including a filter medium, which separates the filtration unit into an input compartment and an output compartment. The filter medium includes at least one hydrophilic material able to absorb or adsorb the virucidal substance. The at least one hydrophilic material includes either porous non-woven material or a porous membrane.Type: GrantFiled: April 19, 2011Date of Patent: March 24, 2015Assignee: MacopharmaInventors: Francis Goudaliez, Thierry Verpoort
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IRRADIATION APPARATUS FOR INACTIVATING PATHOGENS AND/OR LEUKOCYTES IN A BIOLOGICAL FLUID AND PROCESS
Publication number: 20150030500Abstract: The invention relates to an irradiation apparatus for inactivating pathogens and/or leukocytes in a biological fluid such as a platelet suspension and/or plasma comprising: a casing (2), a support member (3) for carrying at least one irradiation bag (19) containing the biological fluid, a light source (4) comprising two banks of light (5, 6) disposed above and below the support member (3), and an agitating system (25) for moving the support member (3), the light source generating UVC light of suitable intensity to inactivate pathogens and/or leukocytes and the agitation system moving the support member in an orbital path with predetermined amplitude and rotational frequency suitable to expose the whole biological fluid to UVC.Type: ApplicationFiled: July 11, 2014Publication date: January 29, 2015Applicant: MACO PHARMA S.A.Inventors: Wolfram Hubert Walker, Frank Tolksdorf, Thierry Verpoort, Francis Goudaliez, Maurice Behague, Arnaud Chavatte -
Irradiation apparatus for inactivating pathogens and/or leukocytes in a biological fluid and process
Patent number: 8778263Abstract: The invention relates to an irradiation apparatus for inactivating pathogens and/or leukocytes in a biological fluid such as a platelet suspension and/or plasma comprising: a casing (2), a support member (3) for carrying at least one irradiation bag (19) containing the biological fluid, a light source (4) comprising two banks of light (5, 6) disposed above and below the support member (3), and an agitating system (25) for moving the support member (3), the light source generating UVC light of suitable intensity to inactivate pathogens and/or leukocytes and the agitation system moving the support member in an orbital path with predetermined amplitude and rotational frequency suitable to expose the whole biological fluid to UVC.Type: GrantFiled: June 17, 2008Date of Patent: July 15, 2014Assignee: Maco Pharma S.A.Inventors: Wolfram Hubert Walker, Frank Tolksdorf, Thierry Verpoort, Francis Goudaliez, Maurice Behague, Arnaud Chavatte -
Publication number: 20130292320Abstract: One aspect of the disclosure relates to a filtration unit intended to allow the removal of leukocytes from a fluid such as blood or a blood component, the unit containing a porous element including a medium for the removal of leukocytes by adsorption and filtration of the leukocytes. The disclosure also relates to a bag-based system including such a unit, said system being in particular arranged for the sterile and closed-circuit filtration of the fluid.Type: ApplicationFiled: July 1, 2013Publication date: November 7, 2013Inventors: Thierry Verpoort, Stephane Chollet
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Patent number: 8388597Abstract: The invention includes a bag system for collecting a biological fluid, in particular blood. The system includes a device for collecting the fluid which is in fluid communication with at least one fluid collection bag, and a device for sampling the fluid to be collected which includes at least one sampling receptacle. The sampling device includes a device for transferring the fluid from the bag system into the sampling receptacle or receptacles, in which the transfer device is provided with a device for associating the receptacle or receptacles. The transfer device may be arranged to allow the support of the receptacle or receptacles in a standby position, the guidance of the receptacle or receptacles to a transfer position and, after transfer, the dissociation of the receptacle or receptacles from the bag system.Type: GrantFiled: October 27, 2009Date of Patent: March 5, 2013Assignee: MacopharmaInventors: Sylvie Demay, Francis Goudaliez, Thierry Verpoort
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Publication number: 20110192798Abstract: A filtering unit for removing a virucidal substance from a biological fluid including an outer casing having at least one input aperture and at least one output aperture. The outer casing including a filter medium, which separates the filtration unit into an input compartment and an output compartment. The filter medium includes at least one hydrophilic material able to absorb or adsorb the virucidal substance. The at least one hydrophilic material includes either porous non-woven material or a porous membrane.Type: ApplicationFiled: April 19, 2011Publication date: August 11, 2011Inventors: Francis Goudaliez, Thierry Verpoort
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Patent number: 7879000Abstract: The invention concerns a method of collecting a biological fluid, in particular blood, with an anticoagulant and/or preservation solution added, in which the biological fluid is collected by natural flow and the anticoagulant and/or preservation solution is added by pumping, the method making provision for measuring the flow of fluid collected and slaving the pumping speed to the measured flow, so as to obtain continuously during collection a given ratio between the quantity of fluid collected and the quantity of anticoagulant and/or preservation solution added. The invention also concerns a collection machine and bag system for implementing the method.Type: GrantFiled: December 31, 2003Date of Patent: February 1, 2011Assignee: MacopharmaInventors: Maurice Behague, Francis Goudaliez, Thierry Verpoort
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Patent number: 7766854Abstract: A biological fluid collection system including a collecting device, a collecting container, a first channel connecting the two, a sampling bag, a second channel connecting the sampling bag and the first tube and at least one substantially irreversible closure device in an open position on at least the first or second channel. The biological fluid may be blood. A method of collecting biological fluid such as blood using the system so that fluid in the sampling bag is substantially irreversibly prevented from entering the collecting container.Type: GrantFiled: December 6, 2007Date of Patent: August 3, 2010Assignee: MacoPharmaInventors: Francis Goudaliez, Thierry Verpoort
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IRRADIATION APPARATUS FOR INACTIVATING PATHOGENS AND/OR LEUKOCYTES IN A BIOLOGICAL FLUID AND PROCESS
Publication number: 20100178200Abstract: The invention relates to an irradiation apparatus for inactivating pathogens and/or leukocytes in a biological fluid such as a platelet suspension and/or plasma comprising: a casing (2), a support member (3) for carrying at least one irradiation bag (19) containing the biological fluid, a light source (4) comprising two banks of light (5, 6) disposed above and below the support member (3), and an agitating system (25) for moving the support member (3), the light source generating UVC light of suitable intensity to inactivate pathogens and/or leukocytes and the agitation system moving the support member in an orbital path with predetermined amplitude and rotational frequency suitable to expose the whole biological fluid to UVC.Type: ApplicationFiled: June 17, 2008Publication date: July 15, 2010Applicant: MACO PHARMA S.A.Inventors: Wolfram Hubert Walker, Frank Tolksdorf, Thierry Verpoort, Francis Goudaliez, Maurice Behague, Arnaud Chavatte -
Publication number: 20100133203Abstract: The present invention relates to a blood bag system, a method for its manufacture, and a process for reducing pathogens and leucocytes in biological fluids in particular in therapeutic quantities of platelet concentrates (PC) contained in the blood bag system, using UV-light and agitation, wherein part of the plasma of the PC is optionally exchanged against a platelet additive solution.Type: ApplicationFiled: June 22, 2007Publication date: June 3, 2010Inventors: Wolfram Hubert Walker, Frank Tolksdorf, Thierry Verpoort, Francis Goudaliez
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Publication number: 20100049089Abstract: The invention includes a bag system for collecting a biological fluid, in particular blood. The system includes a device for collecting the fluid which is in fluid communication with at least one fluid collection bag, and a device for sampling the fluid to be collected which includes at least one sampling receptacle. The sampling device includes a device for transferring the fluid from the bag system into the sampling receptacle or receptacles, in which the transfer device is provided with a device for associating the receptacle or receptacles. The transfer device may be arranged to allow the support of the receptacle or receptacles in a standby position, the guidance of the receptacle or receptacles to a transfer position and, after transfer, the dissociation of the receptacle or receptacles from the bag system.Type: ApplicationFiled: October 27, 2009Publication date: February 25, 2010Applicant: MacoPharmaInventors: Sylvie Demay, Francis Goudaliez, Thierry Verpoort
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Patent number: 7621298Abstract: A recipient has a body designed to contain a fluid and an orifice by which the fluid may be introduced into the body. The recipient is equipped with a system for the sterile transfer of the fluid from inside the body. The transfer system comprises a deformable and impervious wall, wherein the wall is positioned with respect to the recipient so that it forms a closed and sterile space inside which the orifice is located, a fluid communication device between the closed space and the outside of the recipient, wherein the device may be handled without compromising the sterility, and a seal structure associated with the orifice, wherein the seal structure is at least partially located inside the closed space so that it may be moved between an open position and a closed position of the orifice.Type: GrantFiled: October 24, 2007Date of Patent: November 24, 2009Assignee: Maco Pharma, S.A.Inventors: Francis Goudaliez, Thierry Verpoort
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Patent number: 7618407Abstract: The invention includes a bag system for collecting a biological fluid, in particular blood. The system includes a device for collecting the fluid which is in fluid communication with at least one fluid collection bag, and a device for sampling the fluid to be collected which includes at least one sampling receptacle. The sampling device includes a device for transferring the fluid from the bag system into the sampling receptacle or receptacles, in which the transfer device is provided with a device for associating the receptacle or receptacles. The transfer device may be arranged to allow the support of the receptacle or receptacles in a standby position, the guidance of the receptacle or receptacles to a transfer position and, after transfer, the dissociation of the receptacle or receptacles from the bag system.Type: GrantFiled: December 10, 2007Date of Patent: November 17, 2009Assignee: MacoPharmaInventors: Sylvie Demay, Francis Goudaliez, Thierry Verpoort
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Publication number: 20090071905Abstract: A filtering unit for removing a virucidal substance from a biological fluid including an outer casing having at least one input aperture and at least one output aperture. The outer casing including a filter medium, which separates the filtration unit into an input compartment and an output compartment. The filter medium includes at least one hydrophilic material able to absorb or adsorb the virucidal substance. The at least one hydrophilic material includes either porous non-woven material or a porous membrane.Type: ApplicationFiled: March 24, 2008Publication date: March 19, 2009Inventors: Francis Goudaliez, Thierry Verpoort
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Patent number: 7503901Abstract: The invention concerns a bag system for collecting a biological fluid the system intended for use in a collection machine including a peristaltic pump, the system including, in closed circuit, a fluid collection device, a solution bag containing an anticoagulant and/or preservation solution, and a collection bag intended to receive the fluid collected with the anticoagulant and/or preservation solution added. The collection bag is in fluid communication with the collection device by way of a first tube provided with a connector and with the solution bag by way of a second tube connected to the connector. A device for associating the first and second tubes is provided to allow, between the connector and the association device, the formation of a loop with the second tube, the conformation of the loop being arranged to enable it to be disposed around at least part of a head of a peristaltic pump.Type: GrantFiled: December 31, 2003Date of Patent: March 17, 2009Assignee: MacoPharmaInventors: Maurice Behague, Francis Goudaliez, Thierry Verpoort
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Patent number: 7427278Abstract: An extraction device for a biological fluid with an additive solution in which it is desirable for the additive solution to be present in a particular volume proportion to the biological fluid. The volume proportion of the additive solution is determined by the ratio of cross sections of two tubes, one which supplies the biological fluid to a collecting bag and a second which supplies the additive solution to a collecting bag. The tubes are periodically constricted in constriction areas by a pump. The tubes are configured so that the additive solution and the biological fluid only mix downstream of the constriction areas, thereby reducing the risk of supplying the additive solution to the source of the biological fluid. In an exemplary embodiment the biological fluid is blood collected from a patient or donor and the additive solution is an anticoagulant and/or preservation solution.Type: GrantFiled: November 12, 2002Date of Patent: September 23, 2008Assignee: MacoPharmaInventors: Francis Goudaliez, Thierry Verpoort
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Patent number: 7384416Abstract: A biological fluid collection system including a collecting device, a collecting container, a first channel connecting the two, a sampling bag, a second channel connecting the sampling bag and the first tube and at least one substantially irreversible closure device in an open position on at least the first or second channel. The biological fluid may be blood. A method of collecting biological fluid such as blood using the system so that fluid in the sampling bag is substantially irreversibly prevented from entering the collecting container.Type: GrantFiled: August 12, 2002Date of Patent: June 10, 2008Assignee: MacopharmaInventors: Francis Goudaliez, Thierry Verpoort