Abstract: A pen-enabled editor application for an electronic device is disclosed that provides adaptive guidelines for handwritten text. The adaptive guidelines are generated, in real time with the handwritten text, to allow the user to take advantage of the freeform input possibilities of a blank page, while still benefiting from the neatness and organization that results from writing on a lined page. The adaptive guidelines are generated and have a location and a length that changes with measured aspects of the handwritten input text, as the text is written. The handwritten input text may be provided by a pen device interacting with a display device of the electronic device.

Abstract: Methods for providing information related to selected content and a suggested completion of one or more written words are provided. In one aspect, a method includes invoking an assistant tool, displaying an assistant window on a device display, receiving an indication of a selection of content on the display, generating a query for information associated with the selected content, receiving ranked results from the query, and displaying the received results in the assistant window. In one aspect, a snapshot of the selected content is captured and displayed with the results. In one aspect, a method includes receiving an indication of one or more words being written on the display and providing at least one suggested completion of a word or sentence being written. Systems and machine-readable media are also provided.

Abstract: A note-taking application may be provided as a unified package that includes a full application for an unlocked state of the device, and a limited application for a locked state of the device. A user may perform a trigger action, such as swiping down from a corner, when the device is in a standby mode or displaying a lock screen. In response to the trigger action, the device may execute the limited application, allowing the user to write notes while the device remains in a locked state. The limited application accesses a sandboxed local note store with configurable note persistence, but can communicate with the full application by using secure API calls.

Abstract: An electronic stylus may include a wireless interface, a memory, and a processor. The wireless interface may be configured to send and receive signals to and from at least a first computing system and a second computing system. The memory may be configured to store text. The processor may be configured to store, in the memory, a text string received from the first computing system via the wireless interface, and send, to the second computing system via the wireless interface, the text string received from the first computing system.

Abstract: Devices, systems and methods for controlling a patient's body temperature by endovascular heat exchange.

Abstract: Devices, systems and methods for controlling a patient's body temperature by endovascular heat exchange.

Abstract: Aspects of the subject technology relate to providing shortcut assistance. A graphical element and an associated identifier are displayed on a display device. The graphical element is associated with an application. A predetermined user input to display visual representations of shortcuts on the display device is received. In response to receiving the predetermined user input, a visual representation of a shortcut for the application is displayed. The shortcut, when performed, causes launching of the application.

Abstract: The present invention provides a method of treating BPH using modified pore-forming proteins (MPPs). These MPPs are derived from naturally occurring cytotoxic proteins (nPPs) that kill cells by forming pores or channels in the cell membrane, resulting in cell death. The MPPs are generated by modification of the nPPs such that they are capable of being selectively activated at normal prostate cells. Such modification may include the addition of a prostate-specific protease cleavage site to the activation sequence, and/or the addition of a prostate-specific targeting domain to allow selective targeting of prostate cells. These MPPs are capable of selectively targeting and killing normal prostate cells in vivo. The MPPs may be used either alone or in combination with other therapies for the treatment of BPH.

Abstract: The present invention provides a method of treating BPH using modified pore-forming proteins (MPPs). These MPPs are derived from naturally occurring cytotoxic proteins (nPPs) that kill cells by forming pores or channels in the cell membrane, resulting in cell death. The MPPs are generated by modification of the nPPs such that they are capable of being selectively activated at normal prostate cells. Such modification may include the addition of a prostate-specific protease cleavage site to the activation sequence, and/or the addition of a prostate-specific targeting domain to allow selective targeting of prostate cells. These MPPs are capable of selectively targeting and killing normal prostate cells in vivo. The MPPs may be used either alone or in combination with other therapies for the treatment of BPH.

Abstract: A drug compounding skid for sterile transfer of a compounded drug. The skid includes vessels configured to form a sterile seal of a drug contained therein. The skid may include a sterilization system, a drug transfer system, and a cleaning system. The skid may be used to perform sterile transfer of a compounded drug from the vessels to a holding tank. A skid may include a plurality of drug compounding tanks with agitation devices mounted thereto.

Abstract: Consistent with embodiments of the present disclosure, a Document Layering (DL) platform may enable a user to overlay a color layer and/or an interactive electronic layer on an existing legacy document. Such embodiments may begin by receiving a legacy document and a specification of layers to be added to the legacy document. The legacy document may include, for example, a PDF document. The specified layers may include, for example, color layer design or an interactive layer design. The DL platform may overlay the color design and/or interactive layer design upon the legacy document. Further, the DL platform may output an updated document comprised of the legacy document with the color layer and/or the interactive layer overlaid upon it.

Abstract: A cycling shoe cover is designed to provide maximum protection from the elements such as rain, snow, and cold. It also provides aerodynamic benefit with minimum weight. The cover is flexible unitary made from an elastomer, such as silicone or latex rubber, and is highly elastic and waterproof. The upper part of the cover fits snugly over the cyclist's ankle to prevent water egress into the shoes from above. The lower part of the cover snugly cover and seals to the bottom edge of the shoe without interfering with the cycling shoe's cleat or attachment to the cycle pedal.

Abstract: A Targeted Content Marketing (TCM) platform may be provided. Consistent with embodiments of the present disclosure, TCM platform may enable the dynamic placement of, for example, targeted messages, advertisements and/or onserts (hereinafter referred to as “content”) in various documents. The content may be placed within any portion of the document, including, but not limited to for example, the body, margins, various fields, and any white-space in the document. In addition to being effective with high-volume electronic document processing, TCM platform may be integrated with, but not limited to, for example, outbound printing and communication channels, interactive voice response (IVR) systems, and customer service (CSR) popup message prompts.

Abstract: The present invention provides a method of treating BPH using modified pore-forming proteins (MPPs). These MPPs are derived from naturally occurring cytotoxic proteins (nPPs) that kill cells by forming pores or channels in the cell membrane, resulting in cell death. The MPPs are generated by modification of the nPPs such that they are capable of being selectively activated at normal prostate cells. Such modification may include the addition of a prostate-specific protease cleavage site to the activation sequence, and/or the addition of a prostate-specific targeting domain to allow selective targeting of prostate cells. These MPPs are capable of selectively targeting and killing normal prostate cells in vivo. The MPPs may be used either alone or in combination with other therapies for the treatment of BPH.

Abstract: A drug compounding skid for sterile transfer of a compounded drug. The skid includes vessels configured to form a sterile seal of a drug contained therein. The skid may include a sterilization system, a drug transfer system, and a cleaning system. The skid may be used to perform sterile transfer of a compounded drug from the vessels to a holding tank. A skid may include a plurality of drug compounding tanks with agitation devices mounted thereto.

Abstract: Methods and apparatus for providing purchase intention and consumer preference data to merchants are described. In an embodiment, the process includes receiving, by a server computer from a device at a merchant location, consumer check-in data and then retrieving consumer preferences data and purchase history data. The method also includes retrieving merchant data indicative of items and/or services offered by the merchant, and determining purchase intention data indicative of an item or service that the consumer intends to purchase based on at least one of the consumer preferences data, the consumer purchase history data, and the merchant data. The process then includes transmitting the purchase intention data in real-time to a merchant device at the merchant location.

Abstract: A finishing system for finishing a part using a robot may include a staging fixture, a gripper, and a regrip fixture. The part may include an inner surface, a protrusion, and a notch. The staging fixture may include first pads adapted to engage the protrusion. The gripper may be adapted to couple to the robot and may include a first outer surface and second pads. The first outer surface may be shaped to engage the inner surface of the part and the second pads may be adapted to clamp the protrusion on the part. The regrip fixture may include a tab adapted to engage the notch.

Abstract: An automated system for adapting a gripper to conform to parts having various configurations is disclosed herein. The gripper includes clamp pads having clamp surfaces for clamping protrusions on the parts. The automated system includes an actuator coupled to the gripper, a transfer mechanism engaging the actuator and moveable in response to actuations by the actuator, and a clamp block coupled to and moveable with the transfer mechanism.

Abstract: Disclosed herein are modified proaerolysin (PA) peptide. In some examples, the proteins include a prostate-specific protease cleavage site and can further include a prostate-tissue-specific binding domain which functionally replaces the native PA binding domain. In other examples, the proteins include a furin cleavage site and a prostate tissue-specific binding domain which functionally replaces the native PA binding domain. Methods of using such peptides to treat prostate cancer are also disclosed.