Abstract: A discharge valve includes a valve body, a closure, and a non-rigid valve member. The valve body has a bore that extends between an inlet and an outlet. The closure is seated to the valve body and extends to the bore. The non-rigid valve member has an interior and is fixed within the bore between the inlet and the outlet of the valve, the interior of the non-rigid valve member in fluid communication with the closure for expansion and contraction of the non-rigid valve member. Fire extinguisher assemblies and methods of making fire extinguisher assemblies are also described.

Abstract: The present disclosure provides delivery constructs comprising a carrier coupled to a heterologous payload, wherein coupling of the carrier to the payload can result in transportation of the payload (e.g., a therapeutic payload) into and/or across intact polarized epithelial cells (e.g., epithelial cells of the gut of a mammal). The delivery construct can be part of a pharmaceutical composition that can be orally administered to a subject to provide for improved, effective therapies for treatment of, e.g., inflammatory diseases or autoimmune diseases.

Abstract: This document describes methods by which an autonomous vehicle deploys a simulation scenario while operating in a real-world environment. The vehicle's sensors collect perception data. During a run of the vehicle in a real-world environment, the vehicle's on-board computing system will: (i) receive the perception data; (ii) publish the perception data to a muxing tool of the on-board computing system; (iii) generate simulation data that identifies and labels one or more simulated objects in the environment; (iv) publish the simulation data to the muxing tool; (v) use the muxing tool to add at least a portion of the simulation data to the perception data to yield augmented perception data; and (v) use at least a portion of the augmented perception data to make one or more navigation decisions based for the autonomous vehicle.

Abstract: A spinal implant comprises an implant body extending between an anterior surface and a posterior surface, and including a first vertebral engaging surface and a second vertebral engaging surface. The implant body includes an inner surface that defines at least a first cavity and a second cavity. The cavities are oriented to implant fasteners in alignment with an oblique surgical pathway relative to a bilateral axis of a subject body and adjacent an anterior portion of an intervertebral space of the subject body. Systems and methods are disclosed.

Abstract: A fire suppression system has a tank unit (40, 42, 44, 46). A tank body has a first port and an interior for storing at least one of fire suppressant and driver gas. A discharge assembly is mounted to the first port and has a discharge valve (50, 52) and a first monitoring switch or sensor (230 240) having a normally closed output (532) and a normally open output (534). A first monitoring system (100) is coupled to one of the normally closed output and the normally open output. A second monitoring system (340) is coupled to the other of the normally closed output and the normally open output.

Abstract: A method for spinal disorder diagnosis and treatment planning comprising the steps of: imaging a body including vertebral tissue; acquiring data points corresponding to a surface of the body adjacent to the vertebral tissue with a mixed reality holographic display; transmitting the imaging to a computer database; superimposing a first holographic image of the vertebral tissue with a body image including the surface; and displaying the first holographic image and the body image with the mixed reality holographic display. Systems, spinal constructs, implants and surgical instruments are disclosed.

Abstract: A spinal disorder diagnosis and treatment planning system is provided. The diagnosis and treatment planning system includes a mixed reality holographic display including at least one processor, at least one camera, at least one sensor, and being configured to acquire data points corresponding to a surface of a body adjacent to vertebral tissue. A computer database is configured to transmit imaging of the body including the vertebral tissue to the mixed reality holographic display. The mixed reality holographic display is configured to display a first holographic image of the vertebral tissue superimposed with a body image including the surface. Methods are also disclosed.

Abstract: A system for assessing a status of a spinal implant includes a wearable apparatus having an electronics system and one or more spinal implants in communication with the wearable apparatus. The electronics system includes a first short-range receiver, a first short-range transmitter, and an inertial measurement unit. The wearable apparatus is configured to constrain one or more movements of a wearer when worn. The one or more spinal implants include one or more sensors configured to measure one or more characteristics of a fusion status of the spinal implant, a second short-range receiver, and a second short-range transmitter. The one or more spinal implants are configured to communicate one or more of the measured characteristics to the wearable apparatus via the second transmitter.

Abstract: A fire suppression and isolation system includes an ejection nozzle, a dispersion nozzle, and a valve assembly. The ejection nozzle is positioned between a non-hazard volume and a hazard volume. The dispersion nozzle is spaced apart from the ejection nozzle and is disposed within the hazard volume. The valve assembly is arranged to control a release of a suppression medium from a container to the ejection nozzle and the dispersion nozzle, responsive to a thermal event, such that the suppression medium that is ejected from the ejection nozzle defines a fluid barrier that is disposed between the non-hazard volume and the hazard volume.

Abstract: A spinal implant comprises an implant body extending between an anterior surface and a posterior surface, and including a first vertebral engaging surface and a second vertebral engaging surface. The implant body includes an inner surface that defines at least a first cavity and a second cavity. The cavities are oriented to implant fasteners in alignment with an oblique surgical pathway relative to a bilateral axis of a subject body and adjacent an anterior portion of an intervertebral space of the subject body. Systems and methods are disclosed.

Abstract: A system of creating a simulation scenario definition to simulate behavior of an autonomous vehicle includes a computing device and a computer-readable storage medium having one or more programming instructions. The system identifies an event on which a simulation scenario definition is to be based, identifies one or more log files associated with the event, parses the one or more log files in a time-sequential order and populates the simulation scenario definition with information from the identified log files until an event trigger is detected, identifies an actor from one or more of the log files, infer a shape of the actor, generates one or more simulated tracks that includes the inferred shape for the actor, and adds the simulated tracks to the simulation scenario definition.

Abstract: A system of creating a simulation to simulate behavior of an autonomous vehicle includes a simulation system having an electronic device and a computer-readable storage medium having one or more programming instructions. When executed, the one or more programming instructions cause the electronic device to identify an event that is to be analyzed, receive from an autonomous vehicle system a first data stream that includes event information from one or more vehicle event log files that corresponds to the event, receive from a vehicle dynamics model a second data stream that includes synthetic event information that corresponds to the event, until a switch point is detected operate in a pure log execution stage, upon detection of the switch point operate in a play-forward execution stage, and cause the new simulation to be executed.

Abstract: A ventilation hood system is provided. The ventilation hood system includes a hood body defining an interior through which cooking vapors are passable, a support system affixed to a fixed body and supportive of an entire weight of the hood body and a weight sensing system operably coupled to the support system to sense and monitor the entire weight of the hood body over time.

Abstract: A fire suppression system includes at least one spray nozzle for expelling a fire suppression agent into a space; a first container at least partially filled with a first fire suppression agent. The first fire suppression agent within the first container has a first pressure. A conduit extends from the first container to at least one spray nozzle. A second container is at least partially filled with a second fire suppression agent and is arranged in fluid communication with the conduit. The second fire suppression agent within the second container has a second pressure less than the first pressure. A mixture of the first fire suppression agent and the second fire suppression agent is movable through the conduit to the at least one spray nozzle via the first pressure.

Abstract: The present disclosure provides delivery constructs comprising a carrier coupled to a heterologous payload, wherein coupling of the carrier to the payload can result in transportation of the payload (e.g., a therapeutic payload) into and/or across intact polarized epithelial cells (e.g., epithelial cells of the gut of a mammal). The delivery construct can be part of a pharmaceutical composition that can be orally administered to a subject to provide for improved, effective therapies for treatment of, e.g., inflammatory diseases or autoimmune diseases.

Abstract: A spinal construct includes a first member having a first thread form and an implant cavity configured for disposal of the spinal implant. A second member is engageable with a spinal implant and includes a second thread form configured for engagement with the first thread form. A gauge is coupled to the second member. The gauge is configured to measure a force between the second member and the spinal implant when the second member is engaged with the first member. The second thread form is timed with the first thread form to position the gauge in a selected orientation relative to the spinal implant. Systems and methods are disclosed.

Abstract: The present disclosure relates to isolated non-naturally occurring delivery constructs comprising a bacterial toxin-derived delivery construct coupled to a biologically active therapeutic cargo; wherein the delivery construct is capable of delivering the biologically active cargo via transcytosis transport across an epithelial cell; and wherein the delivery construct does not comprise a bacterial toxin-derived translocation domain or a bacterial toxin-derived catalytic (cytotoxic) domain.

Abstract: A cable bracket that can be used to hold and route electrical cables and other wires. The cable bracket has a base member and a plurality of thin flexible fingers projecting from the base member. The fingers define slots that are each adapted to releasably hold a cable or wire.

Abstract: A pool cover assembly includes a first encapsulation member defining a first side of a pool cover encapsulation, the first encapsulation member comprising a first mating feature. The pool cover assembly further includes a second encapsulation member defining a second side of the pool cover encapsulation, the second encapsulation member comprising a second mating feature. And the pool cover assembly further includes a corner endcap member comprising a third mating feature and a fourth mating feature. The first encapsulation member is coupleable to the corner endcap by the first mating feature and the third mating feature, and the second encapsulation member is coupleable to the corner endcap by the second mating feature and the fourth mating feature. The corner endcap member couples with the first encapsulation member and the second encapsulation member to form a corner of the pool cover encapsulation.

Abstract: A spinal construct includes a first member having a first thread form and an implant cavity configured for disposal of the spinal implant. A second member is engageable with a spinal implant and includes a second thread form configured for engagement with the first thread form. A gauge is coupled to the second member. The gauge is configured to measure a force between the second member and the spinal implant when the second member is engaged with the first member. The second thread form is timed with the first thread form to position the gauge in a selected orientation relative to the spinal implant. Systems and methods are disclosed.