Abstract: Systems and methods are provided for multi-schema analysis of patient specific anatomical features from medical images. The system may receive medical images of a patient and metadata associated with the medical images indicative of a selected pathology, and automatically classify the medical images using a segmentation algorithm. The system may use an anatomical feature identification algorithm to identify one or more patient specific anatomical features within the medical images by exploring an anatomical knowledge dataset. A 3D surface mesh model may be generated representing the one or more classified patient specific anatomical features, such that information may be extracted from the 3D surface mesh model based on the selected pathology. Physiological information associated with the selected pathology for the 3D surface mesh model may be generated based on the extracted information.

Abstract: A registration fixture for use with a surgical navigation system for registration of medical images to a three-dimensional tracking space includes a base frame adapted to be mounted over a flat panel detector of an x-ray medical imaging device, and a side frame having optical tracking markers mounted to the base frame. The base frame includes a first set of radiopaque markers embedded therein in a first predetermined pattern and arranged on a plane, and a second set of radiopaque markers embedded therein in a second predetermined pattern also arranged on another plane, which is spaced from the first set of radiopaque markers. The side frame has a plurality of optical tracking markers and is configured to detachably mount to the base frame.

Abstract: Instances of a single brain computer interface (BCI) system can be implemented on multiple devices. An active instance can control the associated device. The instances can each communicate with a neural decoding system that can receive neural signals from a user, process the neural signals, and output a command based on the processed neural signals. A device running the active instance of can be in communication with the neural decoding system to receive a command. The device can include a display, a non-transitory memory storing instructions, and a processor to execute the instructions to: run an instance of a control program; and execute the task based on the command.

Abstract: The present disclosure relates generally to a process for producing polymer fibers, typically polyacrylonitrile-based fibers, the properties of which are controlled by certain parameters of the process, such as the amount of jet stretch, the amount of wet stretch, and the amount of hot stretch employed. The present disclosure also relates to a process for producing carbon fiber from such polymer fibers.

Abstract: A registration fixture for use with a surgical navigation system for registration of medical images to a three-dimensional tracking space includes a base frame adapted to be mounted over a flat panel detector of an x-ray medical imaging device, and a side frame having optical tracking markers mounted to the base frame. The base frame includes a first set of radiopaque markers embedded therein in a first predetermined pattern and arranged on a plane, and a second set of radiopaque markers embedded therein in a second predetermined pattern also arranged on another plane, which is spaced from the first set of radiopaque markers. The side frame has a plurality of optical tracking markers and is configured to detachably mount to the base frame without piercing a sterilizing drape to be interposed between the base frame and the side frame.

Abstract: A registration fixture for use with a surgical navigation system for registration of medical images to a three-dimensional tracking space includes a base frame adapted to be mounted over a flat panel detector of an x-ray medical imaging device, and a side frame having optical tracking markers mounted to the base frame. The base frame includes a first set of radiopaque markers embedded therein in a first predetermined pattern and arranged on a plane, and a second set of radiopaque markers embedded therein in a second predetermined pattern also arranged on another plane, which is spaced from the first set of radiopaque markers. The side frame has a plurality of optical tracking markers and is configured to detachably mount to the base frame without piercing a sterilizing drape to be interposed between the base frame and the side frame.

Abstract: An electronic gaming table executes player-versus-player playing card games. The gaming table has a display screen where at least one random virtual playing card is virtually delivered to individual player positions for each of the multiple players. The electronic gaming table includes the display screen, a processor associated with memory, player input controls and a playing card masking element at each player position. The playing card masking system at each player position is positioned over an individual position that is a portion of the display screen where the processor directs delivery of the at least one random virtual playing card virtual face down. The playing card masking system includes a three-dimensional element having a visible light transmissive line of sight between the individual position and a player at the individual player position, while excluding visible light transmission to player positions across from or adjacent to the individual player position.

Abstract: An electronic gaming table executes player-versus-player playing card games. The gaming table has a display screen where at least one random virtual playing card is virtually delivered to individual player positions for each of the multiple players. The electronic gaming table includes the display screen, a processor associated with memory, player input controls and a playing card masking element at each player position. The playing card masking system at each player position is positioned over an individual position that is a portion of the display screen where the processor directs delivery of the at least one random virtual playing card virtual face down. The playing card masking system includes a three-dimensional element having a visible light transmissive line of sight between the individual position and a player at the individual player position, while excluding visible light transmission to player positions across from or adjacent to the individual player position.

Abstract: Methods for forming a multi-layered nanoscale structure by forming a stack of individual polymeric layers on a substrate are provided. Each individual polymeric layer comprises a cured polymeric material immobilizing a pattern of magnetic nanoparticles. The pattern of magnetic nanoparticles can be different within each individual polymeric layer due to their nature of formation.

Abstract: The disclosure is in part directed to crystalline forms of 6-O-(4-dimethylaminoethoxy)cinnamoyl fumagillol and variants thereof.

Abstract: This disclosure features compositions (e.g., re-constitutable solids, such as lyophilized cakes; or liquid compositions, such as solutions or suspensions, e.g., reconstituted lyophilized cakes) that are suitable for subcutaneous administration. The compositions include a crystalline form (e.g., Form A) of 6-O-(4-dimethylaminoethoxy)cinnamoyl fumagillol, free base and one or more pharmaceutically acceptable excipients and/or one or more pharmaceutically acceptable carriers (e.g., one or more bulking agents; one or more dispersing agents; one or more buffers; one or more suspending agents; water, e.g., water for injection (“WFI”)).

Abstract: The disclosure is in part directed to crystalline forms of 6-O-(4-dimethylaminoethoxy)cinnamoyl fumagillol and variants thereof.

Abstract: The disclosure is in part directed to crystalline forms of 6-O-(4-dimethylaminoethoxy)cinnamoyl fumagillol and variants thereof.

Abstract: Holster mechanism techniques are described. In one or more implementations, an apparatus comprises a holster configured to secure a device, a hood connected to the holster, and a locking mechanism. The hood comprises a biasing portion configured to receive a force to cause the hood to move between a closed position and an open position. The locking mechanism comprises a first locking portion and a second locking portion configured to engage the first locking portion to secure the hood in the closed position or the open position.

Abstract: The disclosure is in part directed to crystalline forms of an oxalate salt of 6-O-(4-dimethylaminoethoxy)cinnamoyl fumagillol.

Abstract: A knife and sheath assembly includes a sheath including a knife receptacle defining knife-receiving open chamber, a knife stopper located at the knife receptacle and a stretchable part operable to move said knife stopper, a knife including a blade insertable into the knife-receiving open chamber, a handle and a shoulder connected between the blade and the handle and stoppable by the knife stopper to keep the blade in the knife-receiving open chamber, and an operating member including a mounting part affixed to the sheath or the knife and an actuating part connected to the mounting part and operable to force the stretchable part of the sheath against the knife stopper in direction away from the shoulder of the knife.

Abstract: A knife and sheath assembly includes a sheath including a knife receptacle defining knife-receiving open chamber, a knife stopper located at the knife receptacle and a stretchable part operable to move said knife stopper, a knife including a blade insertable into the knife-receiving open chamber, a handle and a shoulder connected between the blade and the handle and stoppable by the knife stopper to keep the blade in the knife-receiving open chamber, and an operating member including a mounting part affixed to the sheath or the knife and an actuating part connected to the mounting part and operable to force the stretchable part of the sheath against the knife stopper in direction away from the shoulder of the knife.

Abstract: The disclosure is in part directed to crystalline forms of an oxalate salt of 6-O-(4-dimethylaminoethoxy)cinnamoyl fumagillol.

Abstract: Methods for forming a multi-layered nanoscale structure by forming a stack of individual polymeric layers on a substrate are provided. Each individual polymeric layer comprises a cured polymeric material immobilizing a pattern of magnetic nanoparticles. The pattern of magnetic nanoparticles can be different within each individual polymeric layer due to their nature of formation.

Abstract: The disclosure is in part directed to crystalline forms of 6-O-(4-dimethylaminoethoxy)cinnamoyl fumagillol and variants thereof.