Abstract: This invention relates to a novel use of IL-1?-ligand/IL-1 receptor disrupting compounds (herein referred to as “IL-1beta Compounds”); such as small molecular compounds disrupting IL-1? ligand—IL-1 receptor interaction, IL-1? antibodies or IL-1 receptor antibodies, e.g. IL-1? binding molecules described herein, e.g. antibodies disclosed herein, e.g. IL-1? binding compounds or IL-1 receptor binding compounds, and/or RNA compounds decreasing either IL-1? ligands or IL-1 receptor protein levels, in the treatment and/or prevention of auto-inflammatory syndromes, e.g. Juvenile rheumatoid arthritis or adult rheumatoid arthritis syndrome and to methods of treating and/or preventing auto-inflammatory syndromes, e.g. Juvenile rheumatoid arthritis or adult rheumatoid arthritis syndrome, in mammals, particularly humans.

Abstract: A vehicle scat includes a sitting part structure and a seatback structure which is arranged so as to pivot at its lower end on the sitting part structure and is covered by a seatback cover and to which, in its upper region on the vehicle sill side, is secured a belt deflector. The belt deflector has a belt runner opening for a seatbelt, which faces in the longitudinal direction of the vehicle. The seatbelt is guided out of an automatic belt roller mechanism, which accommodates one end of the seatbelt, through the belt runner opening in the belt deflector. The belt deflector is covered by the seatback cover which has a belt-passage through-opening which coincides with the belt runner opening and is covered on the front face of the seatback by a belt cover which has a belt-guide slot and is connected to the seatback cover.

Abstract: A novel and useful multi-antenna receiver that receives, demodulates and decodes a broadcast signal, whose modulation and encoding of time and timing information allow for reliable and power-efficient operation. The multi-antenna receiver of the present invention is adapted to eliminate or substantially reduce the reception nulls that occur in receivers having a single antenna that is placed in a fixed position. Two or more antennas are employed whereby the receiver generates a combined signal based on a combination of the individual antenna signals or selects one of the antenna signals for input to the receiver based on desired criteria such as signal-to-noise-and-interference-ratio (SNIR). This results in greater robustness of the communication link by reducing or eliminating reception nulls and by rejecting interference through the selection of the antenna for which the signal-to-interference ratio is higher.

Abstract: This invention relates to a novel use of IL-1?-ligand/IL-1 receptor disrupting compounds (herein referred to as “IL-1beta Compounds”); such as small molecular compounds disrupting IL-1? ligand-IL-1 receptor interaction, IL-1? antibodies or IL-1 receptor antibodies, e.g. IL-1? binding molecules described herein, e.g. antibodies disclosed herein, e.g. IL-1? binding compounds or IL-1 receptor binding compounds, and/or RNA compounds decreasing either IL-1? ligands or IL-1 receptor protein levels, in the treatment and/or prevention of auto-inflammatory syndromes, e.g. Juvenile rheumatoid arthritis or adult rheumatoid arthritis syndrome and to methods of treating and/or preventing auto-inflammatory syndromes, e.g. Juvenile rheumatoid arthritis or adult rheumatoid arthritis syndrome, in mammals, particularly humans.

Abstract: In order to provide a method for the three-dimensional representation of a digital roadmap, which makes greater use of areas near the horizon of the visual representation and provides the user with supplementary information, a provision is made to draw in these areas navigation or orientation-related information as image elements.

Abstract: This invention relates to methods employing IL-1?-ligand/IL-1 receptor disrupting compounds (herein referred to as “IL-1beta Compounds”); such as small molecular compounds disrupting IL-1? ligand-IL-1 receptor interaction, IL-1? antibodies or IL-1 receptor antibodies, e.g. IL-1? binding molecules as described herein, e.g. antibodies disclosed herein, e.g. IL-1? binding compounds or IL-1 receptor binding compounds, and/or RNA compounds decreasing either IL-1? ligands or IL-1 receptor protein levels, in the treatment and/or prevention of auto-inflammatory syndromes, e.g. Juvenile rheumatoid arthritis or adult rheumatoid arthritis syndrome and to methods of treating and/or preventing auto-inflammatory syndromes, e.g. Juvenile rheumatoid arthritis or adult rheumatoid arthritis syndrome, in mammals, particularly humans.

Abstract: A navigational device for guiding a vehicle within a network of traffic routes provides, for guidance purposes, a guide object that is shown in relation to the traffic route in such a manner that the guide object's movement represents driving maneuvers to be performed by the driver. The driver emulates the driving maneuvers shown to him/her and thus follows the previously calculated route.

Abstract: An integrated circuit (IC), a method of operating the IC and devices incorporating the IC. In one embodiment, the IC includes: (1) a monolithic substrate and (2) a time code receiver supported by the monolithic substrate and configured to receive a timing signal and employ the timing signal to adjust a local oscillator of a real time clock (RTC).

Abstract: This invention relates to a novel use of IL-1?-ligand/IL-1 receptor disrupting compounds (herein referred to as “IL-1beta Compounds”); such as small molecular compounds disrupting IL-1? ligand-IL-1 receptor interaction, IL-1? antibodies or IL-1 receptor antibodies, e.g. IL-1? binding molecules described herein, e.g. antibodies disclosed herein, e.g. IL-1? binding compounds or IL-1 receptor binding compounds, and/or RNA compounds decreasing either IL-1? ligands or IL-1 receptor protein levels, in the treatment and/or prevention of auto-inflammatory syndromes, e.g. Juvenile rheumatoid arthritis or adult rheumatoid arthritis syndrome and to methods of treating and/or preventing auto-inflammatory syndromes, e.g. Juvenile rheumatoid arthritis or adult rheumatoid arthritis syndrome, in mammals, particularly humans.

Abstract: This invention relates to a novel use of IL-1?-ligand/IL-1 receptor disrupting compounds (herein referred to as “IL-1beta Compounds”); such as small molecular compounds disrupting IL-1? ligand-IL-1 receptor interaction, IL-1? antibodies or IL-1 receptor antibodies, e.g. IL-1? binding molecules described herein, e.g. antibodies disclosed herein, e.g. IL-1? binding compounds or IL-1 receptor binding compounds, and/or RNA compounds decreasing either IL-1? ligands or IL-1 receptor protein levels, in the treatment and/or prevention of auto-inflammatory syndromes, e.g. Juvenile rheumatoid arthritis or adult rheumatoid arthritis syndrome and to methods of treating and/or preventing auto-inflammatory syndromes, e.g. Juvenile rheumatoid arthritis or adult rheumatoid arthritis syndrome, in mammals, particularly humans.

Abstract: A downhole mud motor includes, a stator, a rotor in operable communication with the stator, and a plurality of nanoparticles embedded in at least a portion of the stator

Abstract: The invention relates to an internal combustion engine having at least one combustion chamber, wherein a surface of at least one component of the combustion chamber and/or of an internal-combustion-engine component which is close to the combustion chamber and carries the exhaust gas stream is at least partially coated with a catalytic coating, said surface coming into contact with an air-fuel mixture or with an exhaust gas stream. The invention provides that the catalytic coating has a nanostructure composed of oblong structural elements, wherein the first ends of the structural elements adhere to the coated surface and the second ends of the structural elements project into the combustion chamber or into the space which carries the exhaust gas stream. Such a coating is preferably produced according to the gas flow sputtering method or according to the magnetron sputtering method.

Abstract: This invention relates to methods employing IL-1?-ligand/IL-1 receptor disrupting compounds (herein referred to as “IL-1beta Compounds”); such as small molecular compounds disrupting IL-1? ligand-IL-1 receptor interaction, IL-1? antibodies or IL-1 receptor antibodies, e.g. IL-1? binding molecules as described herein, e.g. antibodies disclosed herein, e.g. IL-1? binding compounds or IL-1 receptor binding compounds, and/or RNA compounds decreasing either IL-1? ligands or IL-1 receptor protein levels, in the treatment and/or prevention of auto-inflammatory syndromes, e.g. Juvenile rheumatoid arthritis or adult rheumatoid arthritis syndrome and to methods of treating and/or preventing auto-inflammatory syndromes, e.g. Juvenile rheumatoid arthritis or adult rheumatoid arthritis syndrome, in mammals, particularly humans.

Abstract: This invention relates to methods employing IL-1?-ligand/IL-1 receptor disrupting compounds (herein referred to as “IL-1beta Compounds”); such as small molecular compounds disrupting IL-1? ligand-IL-1 receptor interaction, IL-1? antibodies or IL-1 receptor antibodies, e.g. IL-1? binding molecules as described herein, e.g. antibodies disclosed herein, e.g. IL-1? binding compounds or IL-1 receptor binding compounds, and/or RNA compounds decreasing either IL-1? ligands or IL-1 receptor protein levels, in the treatment and/or prevention of auto-inflammatory syndromes, e.g. Juvenile rheumatoid arthritis or adult rheumatoid arthritis syndrome and to methods of treating and/or preventing auto-inflammatory syndromes, e.g. Juvenile rheumatoid arthritis or adult rheumatoid arthritis syndrome, in mammals, particularly humans.

Abstract: The invention relates to an ultrasonic sensor (2) in particular a motor vehicle ultrasonic sensor, comprising a housing (4), and a diaphragm (6) which is supported in or on a section (12) of the housing (4) and which has a diaphragm base (8) and a substantially cylindrical wall section (18) adjoining the diaphragm base (8), at least one stabilizing and/or attenuating auxiliary element (22, 30, 32) being arranged on or in the wall section (18) of the diaphragm (6).

Abstract: In order to provide a method that uses the region of a visual depiction of a digital road map in the vicinity of and above the horizon to convey to the user an enhanced impression of depth, provision is made that a plurality of image objects are drawn in the region of the horizon and thereabove, the individual image objects shifting with respect to one another upon a change in the position or travel direction of the vehicle.

Abstract: A method and a system for coding and reading out information in a microscopic cluster formed with coupled functional islands includes: generating the cluster by forming a regular microscopic pattern for locating the functional islands; making use of a physical or chemical property of each individual island and making use of the coupling between the functional islands; assigning different information to different energy levels of the cluster; effecting a change of the physical or chemical property of at least one functional island in order to change the energy level of the cluster to the energy level equivalent to the information content to be coded; and reading out the information. These measures allow forming a cluster having distinct energy levels, each being assigned to a distinct information content.

Abstract: Ultrasound sensor (2), in particular motor vehicle ultrasound sensor, having a housing (4), having a diaphragm (6) which is mounted in or on a section (12) of the housing (4), and having a decoupling element (10) which extends at least partially between the diaphragm (6) and the housing section (12), wherein the decoupling element (10) and the housing section (12) have latching means (14) by means of which the decoupling element (10) and the housing section (12) are connected to one another.

Abstract: A vehicle seat is provided, in particular a commercial vehicle seat, having a scissor-type stand (3) that can vibrate and comprises a bottom frame (5), a top frame (7), two first rocker arms (8a) and two second rocker arms (8b) that intersect in pairs at a scissor axis (10) extending in a transverse seat direction (y). At least one first rocker arm (8a) is supported at one end by at least one bearing mechanism (20) on the top frame (7) or on the bottom frame (5) so as to be able to rotate and vibrate in the longitudinal seat direction (x). The at least one bearing mechanism (20) has at least one damping spring (26), which elastically absorbs and dampens vibrations in the longitudinal seat direction (x).