Abstract: The present invention relates to a new path to synthesize crystalline Tafamidis polymorphs starting from a Tafamidis acetic acid adduct. In addition, this invention relates to a process to synthesize Tafamidis (2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid*(2R,3R,4R,5S)-6-(methyl-amino)-hexane-1,2,3,4,5-pentol), new Tafamidis crystalline polymorphs, a pharmaceutical compositions comprising the new crystalline polymorphs and to the therapeutic use of such new polymorphs.

Abstract: An electronic module for power control includes a carrier element, at least one power switching element having a cooling surface, and a cooling body. The at least one power switching element may be electrically connected to the carrier element. In an assembled state of the electronic module, the cooling body may be thermally conductively connected directly to the cooling surface of the power switching element. When a busbar is present, the busbar may be arranged between the carrier element and the at least one power switching element thereby producing an electrical connection between the carrier element and the at least one power switching element.

Abstract: A valve for closing a fluid line, comprising: an inlet element with an inlet line; an outlet element with an outlet line; a closing element which, in a first state, allows a fluid passage between the inlet line and the outlet line and which, in a second state, closes the fluid passage, wherein the closing element, in the first state, is fixedly connected to the inlet element or the outlet element and, in the second state, is detached from the inlet element or the outlet element; an actuator which, when actuated, is configured to move the closing element from the first state towards the second state; and a pretension element which is pretensioned and is configured to move the closing element into the second state after actuation of the actuator.

Abstract: A transmission may include a housing and also a power electronics module, the power electronics module including a carrier element with at least one power switching element with a cooling surface and also a cooling body, which may be connected in a thermally conductive manner to the cooling surface of the at least one power switching element. The housing may have an oil space for at least partially accommodating transmission components. The power electronics module may be at least partially arranged inside the oil space of the transmission.

Abstract: A power module has a plurality of packaged power semiconductors, a printed circuit board, a heat sink, and possibly a sealing compound. The power semiconductors have electrically conductive connection elements and heat removal areas on respective outer sides. The power semiconductors are arranged on a cooling surface of the heat sink and has its heat removal area connected to the cooling surface of the heat sink to conduct heat, and the printed circuit board is arranged on a side of the power semiconductors that is opposite the heat sink in an orthogonal direction, wherein the connection elements of the power semiconductors make electrical contact with pads on the printed circuit board regions, for example, laterally beside an edge of the heat sink, in which a projection of the heat sink onto the printed circuit board in the orthogonal direction does not cover the connection elements.

Abstract: The disclosure relates to an electronic unit with a circuit board having at least one component arranged on a main surface of the circuit board and a casing element, which incorporates the at least one component, as well as with an ESD protection arrangement for the circuit board. According to the disclosure, open areas on the circuit board, which are not covered by the casing element, are covered with a gold layer directly mounted on a copper surface of the circuit board.

Abstract: A method for determining a current that flows through a load, wherein the current comprises a DC component and a dithering component, and the dithering component is modified in predetermined time intervals, comprises steps for recording a momentary current; determining a dithering parameter; and determining the current based on the momentary current and the dithering parameter.

Abstract: A fender assembly for an agricultural tractor including a carrier bracket which supports a wheel fender adjacent to a vehicle wheel. A steering mechanism is provided as part of the fender assembly, such that the wheel fender can be rotated relative to the carrier bracket. Accordingly, the rotation of the wheel fender can be controlled based on a steering signal generated by the vehicle steering system, to ensure that the wheel fender accurately follows the movement of the adjacent tractor wheel.

Abstract: A measurement system for matching and/or transmission measurements with respect to a device under test comprising an interface is provided. Said measurement system comprises at least one signal generator comprising at least one signal generator signal path, and at least one receiver comprising at least two receiver signal paths. In this context, a signal of a first signal generator signal path of the at least one signal generator signal path and/or a signal of a first receiver signal path of the at least two receiver signal paths is adaptively phase-shifted and/or amplitude-modified with respect to a signal of a second receiver signal path of the at least two receiver signal paths.

Abstract: The invention relates to an electronic module (100) mounted on a transmission component (112). The electronic module (100) comprises a printed circuit board element (102) that has component side (104) with at least one electronic component (108) and a contact side (106) lying opposite the component side (104), and a heat conducting film (110) that is placed between a surface section of the contact side (106) lying opposite the component (108) and a surface section of the transmission component (112). The printed circuit board element (102) can be or is tightened to the transmission component (112) such that the heat conducting film (110) is pressed against the surface section of the contact side (106) and the surface section of the transmission component (112).

Abstract: This invention relates to the use of Lyocell fibers with a tendency to fibrillate for the manufacture of a nonwoven fibrous web material, in particular for the use in a wipe, by using a foam technique.

Abstract: The invention relates to methods and instruments for the rapid detection and rapid mass spectrometric identification of microbial infective agents in blood or other body fluids. The invention recognizes that blood is not a good environment for the cultivation of microbes and provides a method which (a) largely destroys or dissolves the human particles in body fluids, such as erythrocytes and leukocytes in blood, without impairing the ability of the microbes to reproduce, (b) separates the microbial pathogens from the fluid, (c) cultivates them in a nutrient broth which contains none of the antimicrobial components of the body fluids, (d) separates them from the nutrient broth, and (e) identifies the microbes by a mass spectrum of the microbial proteins. The dissolution of the human particles also releases the microbes nesting in macrophages.

Abstract: A fender assembly for an agricultural tractor including a carrier bracket which supports a wheel fender adjacent to a vehicle wheel. A steering mechanism is provided as part of the fender assembly, such that the wheel fender can be rotated relative to the carrier bracket. Accordingly, the rotation of the wheel fender can be controlled based on a steering signal generated by the vehicle steering system, to ensure that the wheel fender accurately follows the movement of the adjacent tractor wheel.

Abstract: A fender assembly for an agricultural tractor including a carrier bracket which supports a wheel fender adjacent to a vehicle wheel. A steering mechanism is provided as part of the fender assembly, such that the wheel fender can be rotated relative to the carrier bracket. Accordingly, the rotation of the wheel fender can be controlled based on a steering signal generated by the vehicle steering system, to ensure that the wheel fender accurately follows the movement of the adjacent tractor wheel.

Abstract: The invention relates to an electronic module (100) mounted on a transmission component (112). The electronic module (100) comprises a printed circuit board element (102) that has component side (104) with at least one electronic component (108) and a contact side (106) lying opposite the component side (104), and a heat conducting film (110) that is placed between a surface section of the contact side (106) lying opposite the component (108) and a surface section of the transmission component (112). The printed circuit board element (102) can be or is tightened to the transmission component (112) such that the heat conducting film (110) is pressed against the surface section of the contact side (106) and the surface section of the transmission component (112).

Abstract: The invention relates to an electronics module (100) for power control. The electronics module (100) comprises a carrier element (102), which has at least a first power switch element (104) with a first cooling surface (106) and a second power switch element (108) with a second cooling surface (110), a heat sink (126), and a cooling plate (122), which connects the first cooling surface (105) and the second cooling surface (110) to one another as well as to the heat sink (126) in a thermally conductive manner, when the electronics module (100) is installed.

Abstract: The disclosure relates to a control device for controlling a load, wherein the control device comprises the following elements: a first current control valve between a first port of the load and a first potential of an operating voltage; a second current control valve between a second port of the load and a second potential of the operating voltage; a processor configured to actuate the second current control valve when the first current control valve is closed, in order to control a current through the load; and a sampling device for determining an input voltage through the first current control valve, wherein the processor is configured to determine the presence of a short circuit between the first port and the first potential if the input voltage does not increase when the first current control valve is opened gradually.

Abstract: A prechamber assembly for an internal combustion engine is disclosed. The prechamber assembly may have a prechamber housing with a first prechamber housing portion and a second prechamber housing portion. The first prechamber housing portion and the second prechamber housing portion may define a prechamber volume. The prechamber assembly may also have a cooling system. The cooling system may be configured to cool at least one of the first prechamber housing portion and the second prechamber housing portion based on a flow of a cooling fluid through the cooling system. The cooling system may have at least one cooling channel formed within the prechamber housing.

Abstract: A wheel of a vehicle, in particular a motor vehicle, has a rim, a hub portion, and at least two spokes connecting the hub portion to the rim. At least one free space between the spokes is covered at least in part by a substantially planar covering element. The covering element is produced from two different material layers.

Abstract: Control center for an aerial device, said aerial device comprising a main boom part mounted on a turret, the main boom part being inclinable around a horizontal axis in a first inclination movement, rotatable around a vertical axis in a rotation movement, and extendable and retractable in a first telescopic movement, wherein the control center comprises a first control device configured for controlling the first inclination movement and the rotation movement of the main boom part, and a second control device comprising at least a first control lever for controlling the first telescopic movement.