Patents by Inventor Thomas A. McDonald

Thomas A. McDonald has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10832859
    Abstract: A hardened inductive device and systems and methods for protecting the inductive device from impact is provided. The inductive device is hardened with protective coating and/or an armor steel housing. The hardened inductive device is protected from impact by an object such as a bullet and leakage of dielectric fluid is prevented. Acoustic and vibration sensors are provided to detect the presence and impact, respectively, of an object in relation to the inductive device housing. The measurements of the acoustic and vibration sensors are compared to thresholds for sending alarms to the network control center and initiating shut-down and other sequences to protect the active part. The acoustic sensor results are utilized to determine the location of origin of the projectile.
    Type: Grant
    Filed: August 19, 2019
    Date of Patent: November 10, 2020
    Assignee: ABB Schweiz AG
    Inventors: George K. Frimpong, Alberto Prieto, Mirrasoul J. Mousavi, James Stoupis, Ed G teNyenhuis, Jeremy R. Schueler, Andrew Bleich, Elizabeth D. Sullivan, Claude J. Lambert, Petter A. Fiskerud, Andrew J. Wall, Gary C. McLeish, Thomas McDonald, Ronald A. Kupiec
  • Publication number: 20200197343
    Abstract: The present invention is directed to novel anti-inflammatory immunomodulators including creatinine or a creatinine salt, for example, creatinine hydrochloride. The present invention is also directed to methods for treating inflammation and inducing an immunomodulatory response. In particular, the anti-inflammatory immunomodulators are useful for treating an inflammatory condition or an autoimmune disease.
    Type: Application
    Filed: January 6, 2020
    Publication date: June 25, 2020
    Applicants: Vireo Systems, Inc., Creighton University
    Inventors: Thomas McDonald, Kristen Drescher
  • Patent number: 10679787
    Abstract: A hardened inductive device and systems and methods for protecting the inductive device from impact is provided. The inductive device is hardened with protective coating and/or an armor steel housing. The hardened inductive device is protected from impact by an object such as a bullet and leakage of dielectric fluid is prevented. Acoustic and vibration sensors are provided to detect the presence and impact, respectively, of an object in relation to the inductive device housing. The measurements of the acoustic and vibration sensors are compared to thresholds for sending alarms to the network control center and initiating shut-down and other sequences to protect the active part. The acoustic sensor results are utilized to determine the location of origin of the projectile.
    Type: Grant
    Filed: August 19, 2019
    Date of Patent: June 9, 2020
    Assignee: ABB Schweiz AG
    Inventors: George K. Frimpong, Alberto Prieto, Mirrasoul J. Mousavi, James Stoupis, Ed G teNyenhuis, Jeremy R. Schueler, Andrew Bleich, Elizabeth D. Sullivan, Claude J. Lambert, Petter A. Fiskerud, Andrew J. Wall, Gary C. McLeish, Thomas McDonald, Ronald A. Kupiec
  • Publication number: 20200150097
    Abstract: The disclosure relates to a system for liquid sample introduction into a chromatography system. The system includes a syringe, a first valve in fluid communication with the syringe, a second valve in fluid communication with the sample, a vessel located between, and in fluid communication with, the first and second valves, a third valve in fluid communication with the first valve, the second valve and a chromatography column, and a pump in fluid communication with the third valve and a mobile phase. When the valves are in a first position the syringe draws the sample into the vessel. The mobile phase flows to the chromatography column. When the valves are in a second position, a portion of the mobile phase flows into the vessel, mixing with and pressurizing the sample. When the valves are in a third position, the mixed and pressurized sample flows to the chromatography column.
    Type: Application
    Filed: November 8, 2019
    Publication date: May 14, 2020
    Applicant: Waters Technologies Corporation
    Inventors: Jason Hill, Abhijit Tarafder, Michael O. Fogwill, Thomas McDonald, Sylvain Cormier
  • Publication number: 20200058439
    Abstract: A hardened inductive device and systems and methods for protecting the inductive device from impact is provided. The inductive device is hardened with protective coating and/or an armor steel housing. The hardened inductive device is protected from impact by an object such as a bullet and leakage of dielectric fluid is prevented. Acoustic and vibration sensors are provided to detect the presence and impact, respectively, of an object in relation to the inductive device housing. The measurements of the acoustic and vibration sensors are compared to thresholds for sending alarms to the network control center and initiating shut-down and other sequences to protect the active part. The acoustic sensor results are utilized to determine the location of origin of the projectile.
    Type: Application
    Filed: August 19, 2019
    Publication date: February 20, 2020
    Inventors: George K. Frimpong, Alberto Prieto, Mirrasoul J. Mousavi, James Stoupis, Ed G teNyenhuis, Jeremy R. Schueler, Andrew Bleich, Elizabeth D. Sullivan, Claude J. Lambert, Petter A. Fiskerud, Andrew J. Wall, Gary C. McLeish, Thomas McDonald, Ronald A. Kupiec
  • Patent number: 10525027
    Abstract: The present invention is directed to novel anti-inflammatory immunomodulators including creatinine or a creatinine salt, for example, creatinine hydrochloride. The present invention is also directed to methods for treating inflammation and inducing an immunomodulatory response. In particular, the anti-inflammatory immunomodulators are useful for treating an inflammatory condition or an autoimmune disease.
    Type: Grant
    Filed: May 15, 2018
    Date of Patent: January 7, 2020
    Assignees: Vireo Systems, Inc., Creighton University
    Inventors: Thomas McDonald, Kristen Drescher
  • Publication number: 20190378649
    Abstract: A hardened inductive device and systems and methods for protecting the inductive device from impact is provided. The inductive device is hardened with protective coating and/or an armor steel housing. The hardened inductive device is protected from impact by an object such as a bullet and leakage of dielectric fluid is prevented. Acoustic and vibration sensors are provided to detect the presence and impact, respectively, of an object in relation to the inductive device housing. The measurements of the acoustic and vibration sensors are compared to thresholds for sending alarms to the network control center and initiating shut-down and other sequences to protect the active part. The acoustic sensor results are utilized to determine the location of origin of the projectile.
    Type: Application
    Filed: August 19, 2019
    Publication date: December 12, 2019
    Inventors: George K. Frimpong, Alberto Prieto, Mirrasoul J. Mousavi, James Stoupis, Ed G. teNyenhuis, Jeremy R. Schueler, Andrew Bleich, Elizabeth D. Sullivan, Claude J. Lambert, Petter A. Fiskerud, Andrew J. Wall, Gary C. McLeish, Thomas McDonald, Ronald A. Kupiec
  • Publication number: 20190314340
    Abstract: An antimicrobial composition containing a synergistic combination of an imidazole antifungal agent and activated creatinine is provided, wherein the imidazole antifungal agent represents in the range of about 0.5 mol % to about 30 mol % of the combination of the antifungal agent and the activated creatinine in the composition. Methods for treating bacterial infections, fungal infections, viral infections, and wounds are also provided, as are other methods of use, including methods for disinfecting inert surfaces, methods for preserving food products, and methods for treating plants. In addition, the invention provides a method for enhancing the antifungal effect of an imidazole antifungal agent as well as a method for enhancing the antibacterial effect of activated creatinine. Compositions and methods involving use of activated 2-amino-imidazol-4-one analogs other than activated creatinine are also provided.
    Type: Application
    Filed: December 27, 2017
    Publication date: October 17, 2019
    Inventors: Thomas McDonald, Steven M. Tracy
  • Patent number: 10431375
    Abstract: A hardened inductive device and systems and methods for protecting the inductive device from impact is provided. The inductive device is hardened with protective coating and/or an armor steel housing. The hardened inductive device is protected from impact by an object such as a bullet and leakage of dielectric fluid is prevented. Acoustic and vibration sensors are provided to detect the presence and impact, respectively, of an object in relation to the inductive device housing. The measurements of the acoustic and vibration sensors are compared to thresholds for sending alarms to the network control center and initiating shut-down and other sequences to protect the active part. The acoustic sensor results are utilized to determine the location of origin of the projectile.
    Type: Grant
    Filed: October 22, 2015
    Date of Patent: October 1, 2019
    Assignee: ABB Schweiz AG
    Inventors: George K. Frimpong, Alberto Prieto, Mirrasoul J. Mousavi, James Stoupis, Ed G teNyenhuis, Jeremy R. Schueler, Andrew Bleich, Elizabeth D. Sullivan, Claude J. Lambert, Petter A. Fiskerud, Andrew J. Wall, Gary C. McLeish, Thomas McDonald, Ronald A. Kupiec
  • Publication number: 20190170706
    Abstract: A method for injecting a diluted sample in a chromatography system includes merging a flow of a sample and a flow of a diluent to form a flow of a diluted sample. A dilution ratio of the diluted sample equals a sum of the volumetric flow rates of the sample and the diluent divided by the volumetric flow rate of the sample. The diluted sample is stored in a holding element before injection into a chromatographic system flow. Sample dilution occurs under low pressure relative to the chromatographic flow thereby allowing lower pressure sample and diluent syringes to be used. Other benefits include reduced compressibility and a reduction in leaks due to the lower pressure operation. The method avoids problems associated with manual techniques which can introduce errors due, for example, to loss of sample, sample precipitation and adsorption of sample to vials.
    Type: Application
    Filed: May 4, 2017
    Publication date: June 6, 2019
    Inventors: Martin Gilar, Richard W. Andrews, Peyton C. Beals, Thomas McDonald, Keith Fadgen, Jordan Kornfeld, Geoff Gerhardt, Sylvain Cormier
  • Publication number: 20190159415
    Abstract: An automatic vertical farming system may include a frame defining at least one growth area and configured to support a plurality of vertical plant growth structures within the at least one growth area. The system may include at least one light, at least one liquid conduit, and at least one gas conduit. The system may include at least one robot disposed on a top side of the frame and movably supported by the frame. The at least one robot may include at least one tool configured to manipulate the plurality of vertical plant growth structures. The system may include a control system including at least one processor configured to automatically control illumination by the at least one light, liquid flow through the at least one liquid conduit, gas flow through the at least one gas conduit, and operation of the at least one robot.
    Type: Application
    Filed: November 30, 2018
    Publication date: May 30, 2019
    Applicant: OnePointOne, Inc.
    Inventors: Samuel Bernard Clifford Bertram, John Russell Bertram, Sara Sadae Kuwahara, Robert Thomas McDonald, Travis Alexander Woodrow, Scot Andrew Tomer, Paul David Mahacek, Zach Daniel Bellay, Daniel James Buckley, Robert John Drazovich, Ian Scott Knight, Sebastian Alexander Schwartz, Anthony Yu
  • Publication number: 20180250255
    Abstract: The present invention is directed to novel anti-inflammatory immunomodulators including creatinine or a creatinine salt, for example, creatinine hydrochloride. The present invention is also directed to methods for treating inflammation and inducing an immunomodulatory response. In particular, the anti-inflammatory immunomodulators are useful for treating an inflammatory condition or an autoimmune disease.
    Type: Application
    Filed: May 15, 2018
    Publication date: September 6, 2018
    Applicants: Vireo Systems, Inc., Creighton University
    Inventors: Thomas McDonald, Kristen Drescher
  • Patent number: 9993452
    Abstract: The present invention is directed to novel anti-inflammatory immunomodulators including creatinine or a creatinine salt, for example, creatinine hydrochloride. The present invention is also directed to methods for treating inflammation and inducing an immunomodulatory response. In particular, the anti-inflammatory immunomodulators are useful for treating an inflammatory condition or an autoimmune disease.
    Type: Grant
    Filed: December 7, 2015
    Date of Patent: June 12, 2018
    Assignees: Vireo Systems, Inc., Creighton University
    Inventors: Thomas McDonald, Kristen Drescher
  • Publication number: 20170328872
    Abstract: Described are a chromatographic separation device and a method for performing a chromatographic separation. The device two chromatographic separation modules in serial communication. The first module is adapted to receive a gradient includes mobile phase. The second module receives the gradient mobile phase that exits from the first module. The first and second modules include chromatographic sorbents that differ in one or more of composition, particle size and sorbent temperature. The retentivity of the second module is greater than the retentivity of the first module and the chromatographic dispersion of the second module is less than the chromatographic dispersion of the first module. The width of a chromatographic peak eluted from the first module is greater than a width of the same chromatographic peak after elution from the second module. The device has a high peak capacity without the need to pack a full column length with small sorbent particles.
    Type: Application
    Filed: October 30, 2015
    Publication date: November 16, 2017
    Inventors: Martin GILAR, Thomas MCDONALD
  • Patent number: 9683395
    Abstract: An advanced latch for a main door of an aircraft emergency oxygen container can be manually released by a manual release actuator pin to move the main door to an intermediate test position, while pushing the manual release actuator pin further releases the latch completely, causing the main door to open. The latch also can be operated automatically by utilizing a small, lightweight motor or an equivalent pneumatic actuator mechanism to rotate a gear mechanism of the latch.
    Type: Grant
    Filed: June 12, 2014
    Date of Patent: June 20, 2017
    Assignee: B/E Aerospace, Inc.
    Inventors: Girish Kshirsagar, Thomas McDonald, Dominic Nadukudiyil
  • Publication number: 20160175272
    Abstract: The present invention is directed to novel anti-inflammatory immunomodulators including creatinine or a creatinine salt, for example, creatinine hydrochloride. The present invention is also directed to methods for treating inflammation and inducing an immunomodulatory response. In particular, the anti-inflammatory immunomodulators are useful for treating an inflammatory condition or an autoimmune disease.
    Type: Application
    Filed: December 7, 2015
    Publication date: June 23, 2016
    Applicants: Vireo Systems, Inc., Creighton University
    Inventors: Thomas McDonald, Kristen Drescher
  • Publication number: 20160118186
    Abstract: A hardened inductive device and systems and methods for protecting the inductive device from impact is provided. The inductive device is hardened with protective coating and/or an armor steel housing. The hardened inductive device is protected from impact by an object such as a bullet and leakage of dielectric fluid is prevented. Acoustic and vibration sensors are provided to detect the presence and impact, respectively, of an object in relation to the inductive device housing. The measurements of the acoustic and vibration sensors are compared to thresholds for sending alarms to the network control center and initiating shut-down and other sequences to protect the active part. The acoustic sensor results are utilized to determine the location of origin of the projectile.
    Type: Application
    Filed: October 22, 2015
    Publication date: April 28, 2016
    Applicant: ABB Technology AG
    Inventors: George K. Frimpong, Alberto Prieto, Mirrasoul J. Mousavi, James Stoupis, Ed G. teNyenhuis, Jeremy R. Schueler, Andrew Bleich, Elizabeth D. Sullivan, Claude J. Lambert, Petter A. Fiskerud, Andrew J. Wall, Gary C. McLeish, Thomas McDonald, Ronald A. Kupiec
  • Publication number: 20140367976
    Abstract: An advanced latch for a main door of an aircraft emergency oxygen container can be manually released by a manual release actuator pin to move the main door to an intermediate test position, while pushing the manual release actuator pin further releases the latch completely, causing the main door to open. The latch also can be operated automatically by utilizing a small, lightweight motor or an equivalent pneumatic actuator mechanism to rotate a gear mechanism of the latch.
    Type: Application
    Filed: June 12, 2014
    Publication date: December 18, 2014
    Inventors: Girish Kshirsagar, Thomas McDonald, Dominic Nadukudiyil
  • Publication number: 20130243847
    Abstract: Creatinine, creatinine precursors or the pharmaceutically acceptable salts thereof are activated to function as an antibacterial agent which has broad spectrum activity and is beneficially used in a variety of applications, such as antimicrobial wound dressings, compositions for topical delivery of the antibacterial agent and for preventing and/or inhibiting the occurrence or spread of bacterial infection, as well as the growth of odor-causing bacteria, to name a few.
    Type: Application
    Filed: May 1, 2013
    Publication date: September 19, 2013
    Applicant: Board of Regents of the University of Nebraska
    Inventors: Thomas McDonald, Steven Tracy, Annika Weber
  • Patent number: 7935495
    Abstract: The present invention provides a method for the detection of early renal disease in animals. The method includes the steps of (a) obtaining a sample from an animal to be tested and (b) determining the amount of albumin in the sample. An amount of albumin in the range of from 10 ?g/ml to about 300 ?g/ml indicates the presence of early renal disease. The present invention also provides antibodies to canine, feline and equine albumin which can be used to detect the presence of early renal disease.
    Type: Grant
    Filed: January 26, 2007
    Date of Patent: May 3, 2011
    Assignee: Heska Corporation
    Inventors: Thomas McDonald, Wayne Arthur Jensen, Annika Weber, Janet S. Andrews