Patents by Inventor Thomas A. Osborne

Thomas A. Osborne has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10544132
    Abstract: The invention provides a compound of formula (I): or tautomer or a solvate or a pharmaceutically acceptable salt thereof, wherein the various substituents are as defined in the claims. Also provided are pharmaceutical compositions containing the compounds of formula (I), processes for making the compounds and the medical uses of the compounds.
    Type: Grant
    Filed: September 29, 2016
    Date of Patent: January 28, 2020
    Assignees: ASTEX THERAPEUTICS LIMITED, CANCER RESEARCH TECHNOLOGY LIMITED
    Inventors: Gianni Chessari, Steven Howard, Ildiko Maria Buck, Benjamin David Cons, Christopher Norbert Johnson, Rhian Sara Holvey, David Charles Rees, Jeffrey David St. Denis, Emiliano Tamanini, Bernard Thomas Golding, Ian Robert Hardcastle, Celine Florence Cano, Duncan Charles Miller, Martin Edward Mäntylä Noble, Roger John Griffin, James Daniel Osborne, Joanne Peach, Arwel Lewis, Kim Louise Hirst, Benjamin Paul Whittaker, David Wyn Watson, Dale Robert Mitchell
  • Patent number: 10544077
    Abstract: Disclosed is a process for recovering formic acid from a formate ester that allows for recovery of a formic acid product comprising greater than 75 wt. % formic acid. Disclosed is also a process for producing formic acid by carbonylating a carrier alcohol, hydrolyzing the formate ester of the carrier alcohol, and recovering a formic acid product comprising greater than 70 wt. % formic acid. Discloses are carrier alcohols that enable more favorable hydrolysis equilibriums and/or distillation sequences.
    Type: Grant
    Filed: July 24, 2018
    Date of Patent: January 28, 2020
    Assignee: Eastman Chemical Company
    Inventors: Scott Donald Barnicki, Robert Thomas Hembre, Sumit Chakraborty, Vickie Haygood Osborne, Michael Richard Laningham, Stijn Van de Vyver
  • Patent number: 10526311
    Abstract: The invention provides a compound of formula (I): or tautomer or a solvate or a pharmaceutically acceptable salt thereof, wherein the various substituents are as defined in the claims. Also provided are pharmaceutical compositions containing the compounds of formula (I), processes for making the compounds and the medical uses of the compounds.
    Type: Grant
    Filed: September 29, 2016
    Date of Patent: January 7, 2020
    Assignees: ASTEX THERAPEUTICS LIMITED, CANCER RESEARCH TECHNOLOGY LIMITED
    Inventors: Gianni Chessari, Steven Howard, Ildiko Maria Buck, Benjamin David Cons, Christopher Norbert Johnson, Rhian Sara Holvey, David Charles Rees, Jeffrey David St. Denis, Emiliano Tamanini, Bernard Thomas Golding, Ian Robert Hardcastle, Celine Florence Cano, Duncan Charles Miller, Martin Edward Mäntylä Noble, Roger John Griffin, James Daniel Osborne, Joanne Peach, Arwel Lewis, Kim Louise Hirst, Benjamin Paul Whittaker, David Wyn Watson, Dale Robert Mitchell
  • Publication number: 20190381849
    Abstract: A height-adjusting axle assembly separate from and connectable to a trailer frame. A first pair of wheels is connected to a first cross-beam by a first pair of torsion axles such that rotation of the first cross-beam causes rotation of the first pair of torsion axles. A second pair of wheels is connected to a second cross-beam by a second pair of torsion axles such that rotation of the second cross-beam causes rotation of the second pair of torsion axles. An interconnecting bar is pivotally connected to the first cross-beam and the second cross-beam. A first frame rail and a second frame rail are connectable to the trailer frame. The first cross-beam and the second cross-beam are supported by and extend between the first frame rail and the second frame rail.
    Type: Application
    Filed: August 28, 2019
    Publication date: December 19, 2019
    Applicant: Raizer Enterprises, LLC
    Inventors: Kelly Osborne, Thomas L. Sundberg
  • Patent number: 10441256
    Abstract: Among other things, there are disclosed apparatuses and methods for medically sealing an opening in a vessel or wall. For example, in medical applications, a delivery tube is provided for insertion through a sheath into a vessel (e.g. a blood vessel). A dome-shaped seal fixed to a filament, an absorbent and/or compressible buffer, and a locking member are provided in the delivery tube. The delivery tube is configured so that it can be inserted into the vessel through a sheath. Tension is maintained on the filament to hold the seal against the tube or sheath. The sheath is pulled out, which pulls out the tube at the same time, leaving the seal over the opening in the vessel wall. The locking member compresses the buffer against the outside of the vessel and with the filament holds the seal in place against the inside of a vessel.
    Type: Grant
    Filed: March 7, 2016
    Date of Patent: October 15, 2019
    Assignees: Cook Medical Technologies LLC, Cook Biotech Incorporated
    Inventors: Ram H. Paul, Jr., Cleon Stanley, Brian L. Bates, F. Joseph Obermiller, Thomas A. Osborne, Sean D. Chambers
  • Patent number: 10399405
    Abstract: A height-adjusting axle assembly separate from and connectable to a trailer frame. A first pair of wheels is connected to a first cross-beam by a first pair of torsion axles such that rotation of the first cross-beam causes rotation of the first pair of torsion axles. A second pair of wheels is connected to a second cross-beam by a second pair of torsion axles such that rotation of the second cross-beam causes rotation of the second pair of torsion axles. A interconnecting bar is pivotally connected to the first cross-beam and the second cross-beam. A first frame rail and A second frame rail are connectable to the trailer frame. The first cross-beam and the second cross-beam are supported by and extend between the first frame rail and the second frame rail.
    Type: Grant
    Filed: April 27, 2018
    Date of Patent: September 3, 2019
    Assignee: Raizer Enterprises, LLC
    Inventors: Kelly Osborne, Thomas L. Sundberg
  • Publication number: 20190255278
    Abstract: A humidification system can include a heater base, a humidification chamber, and a breathing circuit. A cartridge can be removably coupled to the heater base. The cartridge can include various sensors, probes, sensor wire connectors, heater wire connectors, and/or other features. The cartridge can include features configured to mate with corresponding features on the humidification chamber and the heater base. The cartridge includes a memory, such as an EEPROM, or other suitable storage device. When the cartridge is installed on the heater base, the memory is electrically connected to a processor and/or memory of the heater base. Various models of cartridges can be produced for use with different humidification chambers, breathing circuits, and/or therapies. A connector can be configured to couple an inspiratory conduit to an outlet port of the humidification chamber. The connector can provide a pneumatic connection to the outlet port and an electrical connection to the cartridge.
    Type: Application
    Filed: February 8, 2019
    Publication date: August 22, 2019
    Inventors: Hamish Adrian OSBORNE, Gavin Walsh MILLAR, Stephen David EVANS, Bruce Gordon HOLYOAKE, James William STANTON, David Leon MCCAULEY, Gareth Thomas MCDERMOTT, Nicholas James Michael MCKENNA, Myfanwy Jane Antica NORTON, Adrian John ELSWORTH, Michael John ANDRESEN, Jonathan Andrew George LAMBERT, Sandeep Singh GURM, Tessa Hazel PARIS, Joseph Nathaniel GRIFFITHS, Ping SI, Christopher Gareth SIMS, Elmo Benson STOKS, Dexter Chi Lun CHEUNG, Peter Alan SEEKUP, Po-Yen LIU, Richard Edward LANG, Paul James TONKIN, Ian Lee Wai KWAN
  • Publication number: 20190142429
    Abstract: An occluding device for occluding fluid flow through a lumen of a body vessel. The device comprises a coil and fibers attached to the coil. The coil has about 5 to 60 grams of initial tension to facilitate the coil to fold when deployed. The fibers extend from the coil at a length.
    Type: Application
    Filed: January 16, 2019
    Publication date: May 16, 2019
    Inventors: Robert I. White, Jr., Thomas A. Osborne, Kurt J. Tekulve
  • Patent number: 10213209
    Abstract: An occluding device for occluding fluid flow through a lumen of a body vessel. The device comprises a coil and fibers attached to the coil. The coil has about 5 to 60 grams of initial tension to facilitate the coil to fold when deployed. The fibers extend from the coil at a length.
    Type: Grant
    Filed: February 26, 2016
    Date of Patent: February 26, 2019
    Assignee: COOK MEDICAL TECHNOLOGIES LLC
    Inventors: Robert I. White, Jr., Thomas A. Osborne, Kurt J. Tekulve
  • Publication number: 20180103974
    Abstract: A medical device for use in extraction of emboli from a body vessel is described. The medical device includes a tubular member comprising a proximal end and extending to a distal end, and a collection member having a collapsed configuration and an expanded configuration and being movable therebetween, the collection member having an apical end disposed to the distal end of the tubular member and extending to a basal end defining a body portion therebetween, the apical and basal ends having a second lumen formed therethrough and in fluid communication with the tubular member, the collection member comprising at least one port formed through the body portion.
    Type: Application
    Filed: October 11, 2017
    Publication date: April 19, 2018
    Inventors: Thomas A. Osborne, Charles W. Agnew
  • Patent number: 9770320
    Abstract: A repair device (10) for affixing a migrating stent graft (30) to the interior surface of a vessel wall (31). The repair device includes tubular graft (11) with a bare or uncovered stent (16) affixed to the proximal end (12). The bare stent includes a plurality of distally pointed barbs (17) for securing the repair device to a vessel wall. A second stent (15) is positioned in the passage (14) of the tubular graft to expand the graft against the interior surface of the migrating stent graft (30). Proximally pointing barbs (20) are affixed to the struts of the second stent and extend through the graft material for securing the repair device to the migrating stent graft. Biological glue (22) and other sealing material (23) can be applied to the tubular graft and/or stents for sealing the repair device against the vessel wall and/or the interior of the migrating stent graft.
    Type: Grant
    Filed: April 12, 2005
    Date of Patent: September 26, 2017
    Assignee: Cook Medical Technologies LLC
    Inventors: Scott E. Eells, Thomas A. Osborne
  • Patent number: 9702609
    Abstract: A vessel cooling system may include a beverage holding device, having a bottom with a slit having a length. The system may also include a cooling device, having a convex top configured to be received by a concave bottom of a beverage vessel. The cooling device may have a top sheet of thermoplastic polyurethane, a bottom sheet of thermoplastic polyurethane affixed to the top sheet of thermoplastic polyurethane forming a cavity therebetween, and a shaped depression in the center of the convex top. The cooling device may further include a rigid portion, having a circumference, disposed on the bottom of the cooling device, a lip, having an upper surface with a plurality of raised ridges, formed on the circumference of the rigid portion and configured to contact the perimeter of the concave bottom of the beverage vessel, and coolant, that contracts as its temperature raises, contained within the cavity.
    Type: Grant
    Filed: June 16, 2015
    Date of Patent: July 11, 2017
    Assignee: COLD CAN INNOVATIONS, LLC
    Inventors: Michael P. Robb, Thomas Osborne
  • Patent number: 9619467
    Abstract: A dynamic classification dictionary is built for use in profiling and targeting users for additional relevant content. Behavioral data is gathered from user activity, and user documents and actions are categorized. Author-generated document classification information is analyzed and assigned a first taxonomic noun to characterize the document. User-generated tags characterizing a portion of the document are assigned a second taxonomic noun. Search terms that resulted in the user accessing the document are identified and assigned a third taxonomic noun. Attributes related to the manner in which the document was accessed are evaluated and assigned a fourth taxonomic noun. The document is processed using pattern rules to extract a fifth taxonomic noun. The taxonomic nouns are aggregated into a composite set of taxonomic nouns, and the dynamic classification dictionary is built by storing the composite set of taxonomic nouns.
    Type: Grant
    Filed: July 23, 2012
    Date of Patent: April 11, 2017
    Assignee: CBS INTERACTIVE INC.
    Inventors: Tushar Pradhan, Thomas Osborne, John Potter
  • Publication number: 20170035653
    Abstract: Disclosed is a multi-lumen mixing device that includes a first and second lumen constructed and arranged to separately pass a first and second reagent to a mixing chamber in the device, where the mixing chamber includes a mixing feature that mixes the first and second reagents. The disclosed multi-lumen mixing device may also include a port in fluid communication with the reaction mixing to permit the product of the combined reagents to be injected into a patent.
    Type: Application
    Filed: October 20, 2016
    Publication date: February 9, 2017
    Inventors: Thomas A. Osborne, Jeffry S. Melsheimer, Christopher D. BoseI
  • Patent number: 9555215
    Abstract: A turbulator for promoting mixing of fluids passing through a body lumen includes an elongate flow perturbing component and an elongate shape controlling component freely slidable within the flow perturbing component. The turbulator is adjustable from a low profile, lumen access configuration to a deployed configuration via sliding the shape controlling component within the flow perturbing component. Adjusting the turbulator within a body lumen of a patient induces turbulence within a flow of fluid passing through the body lumen to increase mixing of a treatment fluid with the body fluid by way of the induced turbulence.
    Type: Grant
    Filed: November 12, 2015
    Date of Patent: January 31, 2017
    Assignee: Cook Medical Technologies LLC
    Inventors: James R. Randolph, Thomas A. Osborne
  • Patent number: 9501476
    Abstract: A dynamic classification dictionary is built for use in profiling and targeting users for additional relevant content. Behavioral data is gathered from user activity, and user documents and actions are categorized. Author-generated document classification information is analyzed and assigned a first taxonomic noun to characterize the document. User-generated tags characterizing a portion of the document are assigned a second taxonomic noun. Search terms that resulted in the user accessing the document are identified and assigned a third taxonomic noun. Attributes related to the manner in which the document was accessed are evaluated and assigned a fourth taxonomic noun. The document is processed using pattern rules to extract a fifth taxonomic noun. The taxonomic nouns are aggregated into a composite set of taxonomic nouns, and the dynamic classification dictionary is build by storing the composite set of taxonomic nouns.
    Type: Grant
    Filed: April 7, 2015
    Date of Patent: November 22, 2016
    Assignee: CBS Interactive Inc.
    Inventors: Tushar Pradhan, Thomas Osborne, John Potter
  • Patent number: 9498271
    Abstract: Disclosed is a multi-lumen mixing device that includes a first and second lumen constructed and arranged to separately pass a first and second reagent to a mixing chamber in the device, where the mixing chamber includes a mixing feature that mixes the first and second reagents. The disclosed multi-lumen mixing device may also include a port in fluid communication with the reaction mixing to permit the product of the combined reagents to be injected into a patent.
    Type: Grant
    Filed: October 28, 2010
    Date of Patent: November 22, 2016
    Assignee: Cook Medical Technologies LLC
    Inventors: Thomas A. Osborne, Jeffry S. Melsheimer, Christopher D. Bosel
  • Publication number: 20160262737
    Abstract: Among other things, there are disclosed apparatuses and methods for medically sealing an opening in a vessel or wall. For example, in medical applications, a delivery tube is provided for insertion through a sheath into a vessel (e.g. a blood vessel). A dome-shaped seal fixed to a filament, an absorbent and/or compressible buffer, and a locking member are provided in the delivery tube. The delivery tube is configured so that it can be inserted into the vessel through a sheath. Tension is maintained on the filament to hold the seal against the tube or sheath. The sheath is pulled out, which pulls out the tube at the same time, leaving the seal over the opening in the vessel wall. The locking member compresses the buffer against the outside of the vessel and with the filament holds the seal in place against the inside of a vessel.
    Type: Application
    Filed: March 7, 2016
    Publication date: September 15, 2016
    Inventors: Ram H. Paul, JR., Cleon Stanley, Brian L. Bates, F. Joseph Obermiller, Thomas A. Osborne, Sean D. Chambers
  • Patent number: 9440058
    Abstract: An implantable prosthesis with at least one fenestration in a side wall of that prosthesis is disclosed. The fenestration provides an access port through which a medical device (such as a needle or a cannula) can be directed to enable access to the lumen of the blood vessel which the prosthesis is supporting.
    Type: Grant
    Filed: December 16, 2008
    Date of Patent: September 13, 2016
    Assignee: Cook Medical Technologies, LLC
    Inventors: Thomas A. Osborne, Michael H. Palne
  • Patent number: 9430471
    Abstract: A dynamic classification dictionary is built for use in profiling and targeting users for additional relevant content. Behavioral data is gathered from user activity, and user documents and actions are categorized. Author-generated document classification information is analyzed and assigned a first taxonomic noun to characterize the document. User-generated tags characterizing a portion of the document are assigned a second taxonomic noun. Search terms that resulted in the user accessing the document are identified and assigned a third taxonomic noun. Attributes related to the manner in which the document was accessed are evaluated and assigned a fourth taxonomic noun. The document is processed using pattern rules to extract a fifth taxonomic noun. The taxonomic nouns are aggregated into a composite set of taxonomic nouns, and the dynamic classification dictionary is build by storing the composite set of taxonomic nouns.
    Type: Grant
    Filed: April 7, 2015
    Date of Patent: August 30, 2016
    Assignee: CBS Interactive Inc.
    Inventors: Tushar Pradhan, Thomas Osborne, John Potter