Abstract: Systems, computer program products, and methods are described herein for automatically generating resource distributions. The present invention may be configured to receive a text-based instruction and parse, using a machine learning model, the text-based instruction to generate a structured resource distribution including predicted distribution elements. The present invention may be configured to generate, based on the structured resource distribution, a resource distribution. In some embodiments, the text-based instruction may include an email message, an SMS message, recorded speech converted to text, text input to a chat function, text recognized in an image, and/or the like.

Abstract: Apparatuses and methods for data traffic management in multi-source content delivery are described. The apparatus includes a downloader and a controller. The downloader is coupled to servers via communication links. The controller is configured to determine initial download requests for the servers based on predetermined information about a quality of the links. The controller is also configured to send the initial download requests to the servers with the downloader. The controller is further configured to update the information about the quality of the communication links after the downloader receives data associated with a data file from the servers via the communication links. The controller is also configured to determine subsequent download requests for the servers based on the updated information about the quality of the communication links. The controller of further configured to send the subsequent download requests to the servers via the downloader.

Abstract: The invention provides a compound of formula (I): or tautomer or a solvate or a pharmaceutically acceptable salt thereof, wherein the various substituents are as defined in the claims. Also provided are pharmaceutical compositions containing the compounds of formula (I), processes for making the compounds and the medical uses of the compounds.

Abstract: Implementations described herein relate to methods, systems, and computer-readable media for remote production collaboration tools. The remote production collaboration tools can include one or more client devices, a server providing a single connection point, and an animation server configured to produce an animated production. The one or more client devices may provide motion capture data, audio data, control data, and/or associated timestamps. The animation server is configured to process the motion capture data, audio data, control data, and/or the associated timestamps and create the animated production. The animated production may be transmitted as a video stream.

Abstract: Described herein is a system and process for long read sequencing using PCR primers with incorporated Unique Molecular Identifiers (UMIs) for generating a single molecule consensus for each starting molecule in the sample population. This method reduces the sequencing error rate by generating a consensus from the individual reads in each UMI group, averaging out sequencing errors to give better confidence in the actual sequence, to allow for increased accuracy of quantifying the precise knock-in event, and reporting perfect HDR integration.

Abstract: An apparatus includes a light unit and a controller for providing a controlled humanly visible illumination. A solar converter unit and an energy storage device supply an energy output to enable the light unit to provide the controlled illumination. The solar converter unit is configured to charge the energy storage device during a substantial shade charging condition. The controller includes a processor coupled to manage the controlled illumination, a memory accessible to the processor, and a program stored in the memory for execution by the processor to manage the controlled illumination.

Abstract: Implementations described herein relate to methods, systems, and computer-readable media for remote production collaboration tools. The remote production collaboration tools can include one or more client devices, a server providing a single connection point, and an animation server configured to produce an animated production. The one or more client devices may provide motion capture data, audio data, control data, and/or associated timestamps. The animation server is configured to process the motion capture data, audio data, control data, and/or the associated timestamps and create the animated production. The animated production may be transmitted as a video stream.

Abstract: An apparatus includes a light unit and a controller for providing a controlled humanly visible illumination. A solar converter unit and an energy storage device supply an energy output to enable the light unit to provide the controlled illumination. The solar converter unit is configured to charge the energy storage device during a substantial shade charging condition. The controller includes a processor coupled to manage the controlled illumination, a memory accessible to the processor, and a program stored in the memory for execution by the processor to manage the controlled illumination.

Abstract: An introducer includes a dilator received in a lumen defined by an introducer sheath and including a dilation end extending distally beyond a distal end of the introducer sheath. The introducer sheath includes a flat wire reinforcement having a hollow cylindrical shape sandwiched between an inner PTFE tube and an outer nylon tube. The outer nylon tube includes a distal segment that extends distally beyond the PTFE tube, which extends distally beyond the PTFE tube, which extends distally beyond the flat wire reinforcement. A withdrawal support wire has a distal end attached to a distal end turn of the flat wire reinforcement and extends in a proximal direction in parallel with a longitudinal axis between an outer surface of the nylon tube and an inner surface of the PTFE tube. The withdrawal support wire is configured to be in tension when the sheath is placed in tension to inhibit distal stretch separation breakage.

Abstract: An occluding device for occluding fluid flow through a lumen of a body vessel. The device comprises a coil and fibers attached to the coil. The coil has about 5 to 60 grams of initial tension to facilitate the coil to fold when deployed. The fibers extend from the coil at a length.

Abstract: An apparatus includes a welding electrode and a holder with a primary electrical connection for carrying a welding current. The electrode and the holder may separate easily due to a weak interference fit of the primary electrical connection. Bare hands may provide sufficient force for separation. The electrode and the holder may be configured for self-alignment. A quick-release mechanism may prevent unintentional dislodgement of the electrode from the holder and include a rotation-resistant device for preventing electrode rotation. A secondary electrical connection may be included to supplement or replace the primary electrical connection. A workpiece clamping force, traditionally intended for clamping the electrode to a workpiece, may also be utilized to enable the secondary electrical connection.

Abstract: Disclosed is a multi-lumen mixing device that includes a first and second lumen constructed and arranged to separately pass a first and second reagent to a mixing chamber in the device, where the mixing chamber includes a mixing feature that mixes the first and second reagents. The disclosed multi-lumen mixing device may also include a port in fluid communication with the reaction mixing to permit the product of the combined reagents to be injected into a patent.

Abstract: An introducer includes a dilator received in a lumen defined by an introducer sheath and including a dilation end extending distally beyond a distal end of the introducer sheath. The introducer sheath includes a flat wire reinforcement having a hollow cylindrical shape sandwiched between an inner PTFE tube and an outer nylon tube. The outer nylon tube includes a distal segment that extends distally beyond the PTFE tube, which extends distally beyond the PTFE tube, which extends distally beyond the flat wire reinforcement. A withdrawal support wire has a distal end attached to a distal end turn of the flat wire reinforcement and extends in a proximal direction in parallel with a longitudinal axis between an outer surface of the nylon tube and an inner surface of the PTFE tube. The withdrawal support wire is configured to be in tension when the sheath is placed in tension to inhibit distal stretch separation breakage.

Abstract: Among other things, there are disclosed apparatuses and methods for medically sealing an opening in a vessel or wall. For example, in medical applications, a delivery tube is provided for insertion through a sheath into a vessel (e.g. a blood vessel). A dome-shaped seal fixed to a filament, an absorbent and/or compressible buffer, and a locking member are provided in the delivery tube. The delivery tube is configured so that it can be inserted into the vessel through a sheath. Tension is maintained on the filament to hold the seal against the tube or sheath. The sheath is pulled out, which pulls out the tube at the same time, leaving the seal over the opening in the vessel wall. The locking member compresses the buffer against the outside of the vessel and with the filament holds the seal in place against the inside of a vessel.

Abstract: An occluding device for occluding fluid flow through a lumen of a body vessel. The device comprises a coil and fibers attached to the coil. The coil has about 5 to 60 grams of initial tension to facilitate the coil to fold when deployed. The fibers extend from the coil at a length.

Abstract: An occluding device for occluding fluid flow through a lumen of a body vessel. The device comprises a coil and fibers attached to the coil. The coil has about 5 to 60 grams of initial tension to facilitate the coil to fold when deployed. The fibers extend from the coil at a length.

Abstract: A medical device for use in extraction of emboli from a body vessel is described. The medical device includes a tubular member comprising a proximal end and extending to a distal end, and a collection member having a collapsed configuration and an expanded configuration and being movable therebetween, the collection member having an apical end disposed to the distal end of the tubular member and extending to a basal end defining a body portion therebetween, the apical and basal ends having a second lumen formed therethrough and in fluid communication with the tubular member, the collection member comprising at least one port formed through the body portion.

Abstract: A repair device (10) for affixing a migrating stent graft (30) to the interior surface of a vessel wall (31). The repair device includes tubular graft (11) with a bare or uncovered stent (16) affixed to the proximal end (12). The bare stent includes a plurality of distally pointed barbs (17) for securing the repair device to a vessel wall. A second stent (15) is positioned in the passage (14) of the tubular graft to expand the graft against the interior surface of the migrating stent graft (30). Proximally pointing barbs (20) are affixed to the struts of the second stent and extend through the graft material for securing the repair device to the migrating stent graft. Biological glue (22) and other sealing material (23) can be applied to the tubular graft and/or stents for sealing the repair device against the vessel wall and/or the interior of the migrating stent graft.

Abstract: A vessel cooling system may include a beverage holding device, having a bottom with a slit having a length. The system may also include a cooling device, having a convex top configured to be received by a concave bottom of a beverage vessel. The cooling device may have a top sheet of thermoplastic polyurethane, a bottom sheet of thermoplastic polyurethane affixed to the top sheet of thermoplastic polyurethane forming a cavity therebetween, and a shaped depression in the center of the convex top. The cooling device may further include a rigid portion, having a circumference, disposed on the bottom of the cooling device, a lip, having an upper surface with a plurality of raised ridges, formed on the circumference of the rigid portion and configured to contact the perimeter of the concave bottom of the beverage vessel, and coolant, that contracts as its temperature raises, contained within the cavity.