Abstract: Provided herein are compounds, compositions, and methods for the treatment of diseases and disorders associated with influenza, including VX-787 and derivatives thereof, baloxavir and derivatives thereof, and baloxavir marboxil and derivatives thereof, and protein (e.g., antibody) drug conjugates thereof.

Abstract: A linear-acting electric pump unit and method for operating said unit. A linear-acting electric pump unit comprises an electromagnet and a pump unit. It is to be suitable for delivering gas/liquid mixtures. In order that it may be compactly assembled with other devices, it is to have a central inlet. The fluid delivered by the pump unit flows through the electromagnet and enters the pump unit on one side and leaves it on the other through the non-return valves, each arranged on the same centre line as the electromagnet. The pump unit can be used for delivery of gas/liquid mixtures, preferably in the sphere of combustion engines and their fuel supply systems and exhaust emission control systems.

Abstract: An electromagnet and method for producing an electromagnet. The electromagnet includes a sheet metal casing encompassing a magnetic coil at its end face on a magnetic pole side and extends into an interior of the magnetic coil and forms, in this case, a magnetic pole which interacts with a magnet keeper. The electromagnet enables actuation of a valve, a coupling or a reciprocating pump. The structure is achieved with as few cutting processes as possible to be used for generating the individual parts and as small a number as possible of individual parts is to be used per electromagnet.

Abstract: The present invention relates to a CT imaging system as well as a method for CT imaging is provided. For CT imaging, in practice a scout scan and a main scan of a human subject may be performed. It has been found that a detector signal, provided by a detector which detects the X-ray radiation during the scout scan, may be used on the one hand for determining a respective scout image and on the other hand to determine the bone mineral density of the human subject. Although the scout scan is usually primarily performed for determining the scout image, it is of advantage, if the detector used for detecting the X-ray radiation during the scout scan is formed and/or configured to detect X-ray radiation of a first energy spectrum and to detect X-ray radiation of a different, second energy spectrum. In this case, the detector can provide more precise information about the scout region of the human subject and resulting therefrom in a more precise determination of the bone mineral density.

Abstract: An electromagnetically actuated valve. The electromagnetically actuated valve with a small longitudinal extension, allows great through-flow quantities for the fluid with a small pressure difference. It is intended in this case that it should be producible cost-effectively in large unit numbers. An armature carries a plurality of valve bodies arranged in a point-symmetrical manner which together form a movable valve, wherein the plurality of valve bodies interact with a same plurality of valve seats which together form a stationary valve. The valve can be used along with a pump, a tank and/or other fluid units in assemblies for conveying mixtures of gas and liquid.

Abstract: The present invention relates to a CT imaging system as well as a method for CT imaging is provided. For CT imaging, in practice a scout scan and a main scan of a human subject may be performed. It has been found that a detector signal, provided by a detector which detects the X-ray radiation during the scout scan, may be used on the one hand for determining a respective scout image and on the other hand to determine the bone mineral density of the human subject. Although the scout scan is usually primarily performed for determining the scout image, it is of advantage, if the detector used for detecting the X-ray radiation during the scout scan is formed and/or configured to detect X-ray radiation of a first energy spectrum and to detect X-ray radiation of a different, second energy spectrum. In this case, the detector can provide more precise information about the scout region of the human subject and resulting therefrom in a more precise determination of the bone mineral density.

Abstract: An electromagnet and method for producing an electromagnet. The electromagnet includes a sheet metal casing encompassing a magnetic coil at its end face on a magnetic pole side and extends into an interior of the magnetic coil and forms, in this case, a magnetic pole which interacts with a magnet keeper. The electromagnet enables actuation of a valve, a coupling or a reciprocating pump. The structure is achieved with as few cutting processes as possible to be used for generating the individual parts and as small a number as possible of individual parts is to be used per electromagnet.

Abstract: An electrofluidic assembly and method for its operation. The functions of a reciprocating pump and of a valve should be combined in one assembly. Here, in particular the pump and the valve should interact so that a small number of line connections are required. A pump assembly and a valve are arranged on an identical central line and use a bearing rod jointly for movable bearing of a first solenoid armature which activates a displacement apparatus of the pump assembly on one hand and a second solenoid armature of the valve which activates a group of closing bodies on the other hand. The electrofluidic assembly can be used for monitoring tank systems.

Abstract: A linear-acting electric pump unit and method for operating said unit. A linear-acting electric pump unit comprises an electromagnet and a pump unit. It is to be suitable for delivering gas/liquid mixtures. In order that it may be compactly assembled with other devices, it is to have a central inlet. The fluid delivered by the pump unit flows through the electromagnet and enters the pump unit on one side and leaves it on the other through the non-return valves, each arranged on the same centre line as the electromagnet. The pump unit can be used for delivery of gas/liquid mixtures, preferably in the sphere of combustion engines and their fuel supply systems and exhaust emission control systems.

Abstract: An electromagnetically actuated valve. The electromagnetically actuated valve with a small longitudinal extension, allows great through-flow quantities for the fluid with a small pressure difference. It is intended in this case that it should be producible cost-effectively in large unit numbers. An armature carries a plurality of valve bodies arranged in a point-symmetrical manner which together form a movable valve, wherein the plurality of valve bodies interact with a same plurality of valve seats which together form a stationary valve. The valve can be used along with a pump, a tank and/or other fluid units in assemblies for conveying mixtures of gas and liquid.

Abstract: The present invention comprises methods and compositions for controlling nematode parasitism in host plant. The present invention comprises novel polynucleotides and polypeptides encoded by such polynucleotides comprising one or more nucleic acid sequences disclosed herein having a nucleotide sequence comprising any one of SEQ ID NO: 1-142 or 161, a fragment or variant thereof, or a complement thereof, or a polypeptide sequence comprising any one of SEQ ID NO: 143-160, a fragment or variant thereof.

Abstract: The present invention comprises methods and compositions for controlling nematode parasitism in host plant. The present invention comprises novel polynucleotides and polypeptides encoded by such polynucleotides comprising one or more nucleic acid sequences disclosed herein having a nucleotide sequence comprising any one of SEQ ID NOs: 1-142, a fragment or variant thereof, or a complement thereof, or a polypeptide sequence comprising any one of SEQ ID NOs: 143-159, a fragment or variant thereof.

Abstract: Systems and methods are disclosed for providing wireless remote control of devices, where the sensing/transmitting device is worn by, or affixed to, the operator, and responds in real-time to position or movements. The technology enables the operator to control remote devices, even while the operator is engaged in other activities. For an exemplary musical performance application, the remote control apparatus may take the form of a normal sized ring worn on a finger of a hand that the musician uses to play a musical instrument. The ring senses position or movement, e.g. of one or more fingers of the hand. In the examples, the remote control apparatus uses a capacitive measurement technique to measure an electrical field generated in the vicinity of the hand indicative of position. The musician or operator can finely control a device with the system, e.g. to provide nuanced control of audio effects during the performance.

Abstract: Supercritical fluid-assisted deposition of materials on substrates, such as semiconductor substrates for integrated circuit device manufacture. The deposition is effected using a supercritical fluid-based composition containing the precursor(s) of the material to be deposited on the substrate surface. Such approach permits use of precursors that otherwise would be wholly unsuitable for deposition applications, as lacking requisite volatility and transport characteristics for vapor phase deposition processes.

Abstract: Chemical formulations and methods for removing unwanted material, such as unexposed photoresist, metal oxides, CMP residue, and the like, from semiconductor wafers or other substrates. The formulations utilize a supercritical fluid-based cleaning composition, which may further include (I) co-solvent(s), (II) surfactant(s), (III) chelating agent(s), and/or (IV) chemical reactant(s).

Abstract: A novel lead zirconium titanate (PZT) material having unique properties and application for PZT thin film capacitors and ferroelectric capacitor structures, e.g., FeRAMs, employing such thin film material. The PZT material is scalable, being dimensionally scalable, pulse length scalable and/or E-field scalable in character, and is useful for ferroelectric capacitors over a wide range of thicknesses, e.g., from about 20 nanometers to about 150 nanometers, and a range of lateral dimensions extending to as low as 0.15 ?m. Corresponding capacitor areas (i.e., lateral scaling) in a preferred embodiment are in the range of from about 104 to about 10?2 ?m. The scalable PZT material of the invention may be formed by liquid delivery MOCVD, without PZT film modification techniques such as acceptor doping or use of film modifiers (e.g., Nb, Ta, La, Sr, Ca and the like).

Abstract: An organosilicon precursor for vapor deposition, e.g., low pressure (<100 Torr), plasma-enhanced chemical vapor deposition (PECVD) of a low k, high strength dielectric film, wherein the precursor includes at least one of: (i) silicon-pendant oxiranyl functionality; and (ii) a disilyl moiety of the formula wherein x is an integer having a value of from 0 to 4 inclusive. These precursors are useful for the formation of dielectric films having dielectric constants on the order of ˜3 and less, and a hardness exceeding ˜1 GigaPascals.

Abstract: A method and self assembled monolayer (SAM)-containing compositions for removing bulk and hardened photoresist material from microelectronic devices have been developed. The SAM-containing composition includes at least one solvent, at least one catalyst, at least one SAM component, and optionally a surfactant. The SAM-containing compositions effectively remove the hardened photoresist material while simultaneously passivating the underlying silicon-containing layer(s) in a one step process.

Abstract: A multi-step method for depositing ruthenium thin films having high conductivity and superior adherence to the substrate is described. The method includes the deposition of a ruthenium nucleation layer followed by the deposition of a highly conductive ruthenium upper layer. Both layers are deposited using chemical vapor deposition (CVD) employing low deposition rates.

Abstract: A disclosed wireless remote control apparatus includes a sensor, such as a capacitive sensing plate, and measurement circuitry coupled to the sensor. The measurement circuitry takes real time measurements of an electrical parameter from the sensor. The parameter, such as a capacitance or charge on the plate that relates to an electrical field in the vicinity of the sensor, represents a detection of position or movement of a member within a substantially continuous range in proximity to the sensor. In an example of a ring embodiment of the remote control device, the sensor detects position and/or movements in relation to the operator's finger. The remote control apparatus includes a wireless transmitter for wireless transmission of encoded messages and a controller. The controller controls the transmitter, to set durations of intervals between the message transmissions as a function of the measurements of the electrical parameter.