Abstract: A web-fed press includes at least two printing units and at least one drier for drying at least one printing-material web which is moved through the at least two printing units and printed on at least one side with at least one offset printing ink at each of the printing units. The printing-material web is dried at least after the first printing unit and before the second printing unit.

Abstract: The invention relates to a solid pharmaceutical form obtainable by melt extrusion comprising an LTB4 antagonist, which is embedded in a polymer matrix (solid dispersion).

Abstract: An aircraft cabin that comprises a plurality of compartments (5) for passengers each having side walls (7a, 7b, 15) and accessible via a doorway (9) in one of the side walls (7a, 7b, 15). The compartments (5) include door assemblies for closing the doorways (9) and creating enclosed spaces and chair and other furniture interactively arranged in the compartment (5).

Abstract: A method of applying substances to a land begins with inputting data indicative of the substance requirement for the land into a processor. The land is traversed with a vehicle having an engine and a transmission that can vary the vehicle speed without adjusting the engine speed. The vehicle has an appliance including a mechanism for applying the substance to the land. The appliance application rate is input into the processor with the desired engine speed. The land is traversed with the vehicle with the engine speed set at the desired engine speed. The vehicle position is established, and a signal is generated to indicate a requirement for adjustment to the transmission to change the vehicle speed to match the individual section requirement to the appliance application rate. Lastly, the transmission is adjusted according to the signal generated by the processor.

Abstract: The present invention relates to the compound 3-Z-[1-(4-(N-((4-methyl-piperazin-1-yl)-methylcarbonyl)-N-methyl-amino)-anilino)-1-phenyl-methylene]-6-methoxycarbonyl-2-indolinone-monoethanesulphonate of formula I and the use thereof as a pharmaceutical composition.

Abstract: The present invention relates to the compound 3-Z-[1-(4-(N-((4-methyl-piperazin-1-yl)-methylcarbonyl)-N-methyl-amino)-anilino)-1-phenyl-methylene]-6-methoxycabonyl-2-indolinone-monoethanesulphonate of formula I and the use thereof as a pharmaceutical composition

Abstract: Disclosed are viral variants exhibiting reduced sensitivity to particular agents including nucleoside analogues and immunological mediators such as immunoglobulins and immune cells. Also provided are hepatitis B virus (HBV) variants which exhibit a level of replication fitness in the presence of a nucleoside analogue similar to or greater than in the absence of the nucleoside analogue. The present invention also provides methods of treating HBV infection, including a method for identifying a need to change or otherwise alter an existing therapeutic regimen. Also disclosed are methods for monitoring the development in a subject of an increased HBV load in the presence of a nucleoside analogue. The present invention further provides the use of nucleoside analogue-resistant HBV variants which exhibit a similar or increased replication fitness in the presence of the nucleoside analogue compared to in the absence of the nucleoside analogue to screen for medicaments to treat HBV infection.

Abstract: A doctor blade device for the removal of dampening medium from a soft surface of an ink applicator roller in the inking unit of a printing machine, having at least one doctor blade placed against the surface of the roller and having an edge radius in the range of 2 mm to 10 mm.

Abstract: The invention relates to a new pharmaceutical formulation, containing an LTB4 antagonist of formula I wherein A, R1, R2, R3 and R4 are defined as in claim 1, the pharmacologically acceptable acid addition salt, glycoside, O-sulphate or glucuronide thereof as active substance as well as optionally at least one pharmacologically acceptable excipient and/or carrier, the active substance being present as a solid solution or solid dispersion in a polymer matrix. The invention also relates to the preparation thereof and their use as pharmaceutical compositions as well as the solid solutions and dispersions per se.

Abstract: The invention concerns a process and a device for displaying navigation information on a projection surface in a vehicle, including a navigation system, which by means of a satellite supported system continuously acquires position information for the vehicle, and which by means of an image producing unit produces navigation information or driving directions obtained from the navigation system within an image of the vehicle environment, wherein a reliability value for the position data is determined, and the image producing unit produces the navigation information in various display modes depending upon the reliability value.

Abstract: The invention relates in its first aspect to a rapidly decomposing tablet for pain therapy containing meloxicam [4-hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide] in the form of a salt with an inorganic or organic base providing rapid absorption of the active substance, the process of its preparation by direct tabletting, and furthermore relates in a second aspect to the crystalline meloxicam meglumin salt mono- and dihydrate and the preparation thereof.

Abstract: The present invention relates to the compound 3-Z-[1-(4-(N-((4-methyl-piperazin-1-yl)-methylcarbonyl)-N-methyl-amino)-anilino)-1-phenyl-methylene]-6-methoxycarbonyl-2-indolinone-monoethanesulphonate of formula I and the use thereof as a pharmaceutical composition.

Abstract: The surface of a structural component of a printing machine from which ink or oil-based contamination can be cleaned easily has a hydrophilic character.

Abstract: The invention relates to a new pharmaceutical formulation containing an LTB4 antagonist of formula I 1

Abstract: A chambered doctor blade assembly which can be placed against a roller of an inking unit of a printing machine, in particular onto an engraved roller, has a chamber connected to the surface of the roller by means of an orifice through which printing ink can flow. The orifice can be closed and re-opened by means of a closing element which is arranged within the chamber and which can be brought into a closing position. When the closing element is in the closing position, printing ink can continue to flow through the chamber.

Abstract: A device for metering and equalizing an ink layer on the surface of a printing machine roller, in particular on the surface of an ink applicator roller in the inking unit of a printing machine, the surface being additionally wetted with dampening medium. The device contains at least two doctor blades which are arranged preferably at a short distance one behind the other in the direction of rotation of the roller and rest under pressure against the surface of the roller and of which a front doctor blade, with respect to the direction of rotation of the roller, has a doctor blade edge radius such that essentially only the dampening medium, but not the ink layer, can be wiped off from the surface of the roller by said front doctor blade, while a rear doctor blade, with respect to the direction of rotation of the roller, has, by comparison, a smaller doctor blade edge radius such that at least part of the ink layer which has remained on the surface of the roller can be wiped off.

Abstract: A method of applying substances to a section of land begins with inputting data indicative of the substance requirement for the section of land into a data processor. The area of land is traversed with a vehicle having an engine and a transmission including means for varying the speed of the vehicle without adjustment of the engine speed. The vehicle has at least one appliance comprising an application mechanism for application of the substance to the area attached thereto. The application rate of the appliance is input into the data processor with the desired engine speed. The area of land is traversed with the vehicle with the engine speed set at the desired engine speed. The position of the vehicle is established, and a signal is generated to indicate a requirement for adjustment to the transmission to increase or decrease the speed of the vehicle to match the individual section requirement to the application rate of the appliance.

Abstract: A comfort and illumination unit especially for a passenger space in an aircraft is constructed for cooperation with a straight wall panel that can be integrated in or secured to a vertical straight wall and/or a horizontal straight ceiling wall. The unit has a mounting base and a cover with passenger convenience elements mounted to the base under the cover which is provided with cut-outs for access to the convenience elements. Fluorescent bulbs form a frame around the convenience elements.

Abstract: A device for metering and equalizing an ink layer on the surface of a printing machine roller, in particular on the surface of an ink applicator roller in the inking unit of a printing machine, the surface being additionally wetted with dampening medium. The device contains at least two doctor blades which are arranged preferably at a short distance one behind the other in the direction of rotation of the roller and rest under pressure against the surface of the roller and of which a front doctor blade, with respect to the direction of rotation of the roller, has a doctor blade edge radius such that essentially only the dampening medium, but not the ink layer, can be wiped off from the surface of the roller by said front doctor blade, whilst a rear doctor blade, with respect to the direction of rotation of the roller, has, by comparison, a smaller doctor blade edge radius such that at least part of the ink layer which has remained on the surface of the roller can be wiped off.

Abstract: A chambered doctor blade assembly which can be placed against a roller of an inking unit of a printing machine, in particular onto an engraved roller, has a chamber connected to the surface of the roller by means of an orifice through which printing ink can flow. The orifice can be closed and re-opened by means of a closing element which is arranged within the chamber and which can be brought into a closing position. When the closing element is in the closing position, printing ink can continue to flow through the chamber.