Abstract: This invention relates to thienopyrimidinones and their use as inhibitors of TRPA1 activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of fibrotic diseases, inflammatory and auto-immune diseases and CNS-related diseases.

Abstract: This invention relates to thienopyrimidinones and their use as inhibitors of TRPA1 activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of fibrotic diseases, inflammatory and auto-immune diseases and CNS-related diseases.

Abstract: The present invention encompasses compounds of the formula I which are suitable for the treatment of diseases related to Vanin, and processes for making these compounds, pharmaceutical preparations containing these compounds, and their methods of use.

Abstract: A motor vehicle has a body, a vehicle part, and a spring bolt for fastening the vehicle part in a receptacle of the body. The rotational axis of the spring bolt is arranged in such a way that it has exactly one point of intersection with an XY plane of the motor vehicle.

Abstract: This invention relates to thienopyrimidinones and their use as inhibitors of TRPA1 activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of fibrotic diseases, inflammatory and auto-immune diseases and CNS-related diseases.

Abstract: This invention relates to thienopyrimidinones and their use as inhibitors of TRPA1 activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of fibrotic diseases, inflammatory and auto-immune diseases and CNS-related diseases.

Abstract: The present invention encompasses compounds of the formula I which are suitable for the treatment of diseases related to Vanin, and processes for making these compounds, pharmaceutical preparations containing these compounds, and their methods of use.

Abstract: The present invention encompasses compounds of the formula I which are suitable for the treatment of diseases related to Vanin, and processes for making these compounds, pharmaceutical preparations containing these compounds, and their methods of use.

Abstract: The present invention encompasses compounds of the formula I which are suitable for the treatment of diseases related to Vanin, and processes for making these compounds, pharmaceutical preparations containing these compounds, and their methods of use.

Abstract: The present invention encompasses compounds of the formula I which are suitable for the treatment of diseases related to Vanin, and processes for making these compounds, pharmaceutical preparations containing these compounds, and their methods of use.

Abstract: An activity based monitoring system is disclosed, the activity based monitoring system being configured to monitor a plurality of badges associated with a plurality of assets within a healthcare facility.

Abstract: The present invention provides crystals, and compositions thereof, wherein the crystals include a malic acid salt of N-[2-(diethylamino)ethyl]-5-[(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide. Methods of preparing such crystals are also disclosed.

Abstract: A communication and asset locating and tracking system is provided by a wireless high resolution locating and tracting system having a plurality of receivers that are located in different locations in a facility, such as floors, rooms, corridors, common areas and portions thereof within the facility, the locating system is linked to a wireless communication system having a plurality of access points and voice-activated handfree communicators. By issuing a voice command to the communicator, the location of an asset is determined by the asset location system.

Abstract: A system handling fully automated supplier quality control and enabling quality improvement by using supplier raw data as well as manufacturer manufacturing in-line data is described. The system not only maintains fully automated data transfers and handling, but also enables immediate automated reporting for both the manufacturer and the supplier. Based on this automated notification, communication between sides is thus introduced. The system also enables the transfer from reactive into preventive working mode, concerning supplier quality, giving advantages like early warning, fast feedback. Beyond the so-called automated quality control features, the system supports quality improvement enabling advanced analysis features like yield prediction, specification validation, best of breed analysis, and the like. These capabilities include a close feedback control loop with an adaptation feature to correct the prediction in case of a deviation and/or trend.

Abstract: An activity based monitoring system is disclosed, the activity based monitoring system being configured to monitor a plurality of badges associated with a plurality of assets within a healthcare facility.

Abstract: A system and a corresponding method for the logistic management of supply chains of digitally networked suppliers, wherein supply chain participants that are linked directly within the supply chain are identified and grouped, and wherein, on the side of each of the grouped supply chain participants, logistic requirements for fulfilling local supply activities to the other supply chain participant of the group are determined, logistic information between those two supply chain participants exchanged, and the local logistic requirements on the side of each of the grouped supply chain participants dependent on the contents of the exchanged logistic information controlled. The invention enables decentralized management with considerable less efforts than conventional approaches, wherein collaboration and replenishment between collaborating suppliers are accomplished using a network like the Intranet or Internet.

Abstract: In a multi-color imaging apparatus utilizing a recharge step between two image creation steps for conditioning a charge retentive surface pursuant to forming the second of the two images, a voltage sensitive corona generating device having a high characteristic slope described in a graph of the current delivered to a charge receiving surface (I) vs. grid minus charge receiving surface voltage (V) is used to both reduce the residual toner voltage across the previously toned image, and to charge the toned and untoned areas of the charge retentive surface to a substantially uniform level so that developability conditions for the subsequent image are improved.