Patents by Inventor Thomas Freier

Thomas Freier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11975120
    Abstract: A chitosan for use in an antimicrobial treatment of a patient's tissue and a pharmaceutical composition comprising a chitosan for use in an antimicrobial treatment of a patient's tissue. A method of treating a microbial infection, the method comprising the step of administering to a patient an effective amount of a chitosan and an aqueous solution comprising chitosan. A chitosan or a pharmaceutical composition comprising a chitosan for use in an epithelial cell growth stimulating treatment of a patient's tissue. A method of stimulating the growth of epithelial cells the method comprising the step of administering to a patient or to an epithelial cells containing cell culture an effective amount of a chitosan or a pharmaceutical composition comprising chitosan. A tissue dressing material characterized in that it consists of chitosan or a chitosan comprising composition.
    Type: Grant
    Filed: March 18, 2022
    Date of Patent: May 7, 2024
    Assignee: Medoderm Gmbh
    Inventors: Rivelino Montenegro, Thomas Freier, Karsten Henco
  • Publication number: 20230136330
    Abstract: A chitosan for use in an antimicrobial treatment of a patient's tissue and a pharmaceutical composition comprising a chitosan for use in an antimicrobial treatment of a patient's tissue. A method of treating a microbial infection, the method comprising the step of administering to a patient an effective amount of a chitosan and an aqueous solution comprising chitosan. A chitosan or a pharmaceutical composition comprising a chitosan for use in an epithelial cell growth stimulating treatment of a patient's tissue. A method of stimulating the growth of epithelial cells the method comprising the step of administering to a patient or to an epithelial cells containing cell culture an effective amount of a chitosan or a pharmaceutical composition comprising chitosan. A tissue dressing material characterized in that it consists of chitosan or a chitosan comprising composition.
    Type: Application
    Filed: March 18, 2022
    Publication date: May 4, 2023
    Inventors: Rivelino Montenegro, Thomas Freier, Karsten Henco
  • Publication number: 20220218870
    Abstract: Medical device (10) having a film support structure (12), the film support structure comprising a composition containing chitosan, the film support structure (12) including a surface sculpturing (14). The surface sculpturing (14) comprises a plurality of peaks (16) and troughs (18) defining a plurality of grooves, the peaks (16) having a peak width (PW) ranging from 0.1 to 1000 ?m, preferably 1 to 100 ?m, the troughs have a trough width (TW) ranging from 0.1 to 1000 ?m, preferably 1 to 100 ?m, wherein a peak to trough distance (D) ranges from 0.1 to 1000 ?m.
    Type: Application
    Filed: May 18, 2020
    Publication date: July 14, 2022
    Inventors: Stefano GEUNA, Francesco PORPIGLIA, Thomas FREIER
  • Patent number: 11311644
    Abstract: A chitosan for use in an antimicrobial treatment of a patient's tissue and a pharmaceutical composition comprising a chitosan for use in an antimicrobial treatment of a patient's tissue. A method of treating a microbial infection, the method comprising the step of administering to a patient an effective amount of a chitosan and an aqueous solution comprising chitosan. A chitosan or a pharmaceutical composition comprising a chitosan for use in an epithelial cell growth stimulating treatment of a patient's tissue. A method of stimulating the growth of epithelial cells the method comprising the step of administering to a patient or to an epithelial cells containing cell culture an effective amount of a chitosan or a pharmaceutical composition comprising chitosan. A tissue dressing material characterized in that it consists of chitosan or a chitosan comprising composition.
    Type: Grant
    Filed: July 1, 2019
    Date of Patent: April 26, 2022
    Assignee: Medoderm GmbH
    Inventors: Rivelino Montenegro, Thomas Freier, Karsten Henco
  • Publication number: 20190321511
    Abstract: A chitosan for use in an antimicrobial treatment of a patient's tissue and a pharmaceutical composition comprising a chitosan for use in an antimicrobial treatment of a patient's tissue. A method of treating a microbial infection, the method comprising the step of administering to a patient an effective amount of a chitosan and an aqueous solution comprising chitosan. A chitosan or a pharmaceutical composition comprising a chitosan for use in an epithelial cell growth stimulating treatment of a patient's tissue. A method of stimulating the growth of epithelial cells the method comprising the step of administering to a patient or to an epithelial cells containing cell culture an effective amount of a chitosan or a pharmaceutical composition comprising chitosan. A tissue dressing material characterized in that it consists of chitosan or a chitosan comprising composition.
    Type: Application
    Filed: July 1, 2019
    Publication date: October 24, 2019
    Applicant: MEDODERM GMBH
    Inventors: Rivelino Montenegro, Thomas Freier, Karsten Henco
  • Publication number: 20190240249
    Abstract: A hemostatic material and a method of treating a bleeding wound of a human or an animal include a hemostatic powder for application to the wound. The hemostatic powder comprises a first part consisting of a native chitosan base and a second part consisting of a chitosan salt, where the first and the second parts form the main component of the hemostatic powder, or at least 50% of a total weight of the hemostatic powder, and the second part forms a layer that at least partially coats the first part. The hemostatic powder may be provided in a hemostatic spray formulation that comprises a mixture of the hemostatic powder dispersed in a liquefied gas for release from a cannister onto the wound. A treatment method involves applying the hemostatic spray formulation directly to the wound. Other embodiments are also disclosed.
    Type: Application
    Filed: February 4, 2019
    Publication date: August 8, 2019
    Inventors: Thomas Freier, Rivelino Montenegro, Wayne Grube, JR.
  • Patent number: 10328096
    Abstract: Composition comprising chitosan for use in the prevention and/or treatment of incontinence and/or impotence in a subject undergoing prostatectomy.
    Type: Grant
    Filed: July 5, 2017
    Date of Patent: June 25, 2019
    Assignees: UNIVERSITA' DEGLI STUDI DI TORINO
    Inventors: Thomas Freier, Stefano Geuna, Francesco Porpiglia
  • Patent number: 10207022
    Abstract: A tissue dressing material for being applied in contact with a tissue of a patient. The tissue dressing material's main component is deacetylated native chitosan. Moreover, a liquid tissue dressing material for being applied in contact with a tissue of a patient, the tissue dressing material being an aqueous mixture. The main component of the constituent(s) of the mixture other than water is deacetylated native chitosan.
    Type: Grant
    Filed: September 1, 2009
    Date of Patent: February 19, 2019
    Assignee: MEDODERM GMBH
    Inventors: Rivelino Montenegro, Thomas Freier
  • Publication number: 20180008625
    Abstract: Composition comprising chitosan for use in the prevention and/or treatment of incontinence and/or impotence in a subject undergoing prostatectomy.
    Type: Application
    Filed: July 5, 2017
    Publication date: January 11, 2018
    Inventors: Thomas Freier, Stefano Geuna, Francesco Porpiglia
  • Patent number: 9814800
    Abstract: A kit comprising a tissue dressing material for being applied in contact with the tissue of a patient and a detachment solvent for removing the tissue dressing material from the tissue. A method of treating a tissue of a patient, the method comprising the steps of: applying a water-soluble tissue dressing material in contact with the patient's tissue; and applying an acidic detachment solvent to the tissue dressing material for removing the tissue dressing material from the tissue. A method of treating a tissue of a patient, the method comprising the steps of: applying a liquid tissue dressing material in contact with the patient's tissue; and applying a detachment solvent to the tissue dressing material for removing the tissue dressing material from the tissue.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: November 14, 2017
    Assignee: Medovent GmbH
    Inventors: Rivelino Montenegro, Thomas Freier
  • Patent number: 9771668
    Abstract: A fluid-swellable fiber in particular for the use as a surgical suture, the fiber comprising chitosan, the fiber's swelling ratio being less than 100%, and a fabric comprising the fiber. Moreover, a method of manufacturing from a chitosan-containing solution a fiber comprising chitosan, wherein during manufacture, the solution is brought into contact with a coagulation medium containing at least one organic solvent, a method of removing a fiber from a living organism, wherein the fiber is at least partly dissolved in a solvent applied from the outside, and a kit comprising a chitosan containing fiber and a solvent for at least partly dissolving the fiber.
    Type: Grant
    Filed: February 2, 2010
    Date of Patent: September 26, 2017
    Assignee: Medovent GmbH
    Inventors: Rivelino Montenegro, Thomas Freier
  • Publication number: 20160279284
    Abstract: A kit comprising a tissue dressing material for being applied in contact with the tissue of a patient and a detachment solvent for removing the tissue dressing material from the tissue. A method of treating a tissue of a patient, the method comprising the steps of: applying a water-soluble tissue dressing material in contact with the patient's tissue; and applying an acidic detachment solvent to the tissue dressing material for removing the tissue dressing material from the tissue. A method of treating a tissue of a patient, the method comprising the steps of: applying a liquid tissue dressing material in contact with the patient's tissue; and applying a detachment solvent to the tissue dressing material for removing the tissue dressing material from the tissue.
    Type: Application
    Filed: June 10, 2016
    Publication date: September 29, 2016
    Inventors: Rivelino Montenegro, Thomas Freier
  • Patent number: 9439998
    Abstract: The present invention relates to methods for disinfecting or decontaminating a material or for preventing an infection or contamination of a material. The invention further relates to compositions which are suitable for disinfecting a material or for preventing an infection or contamination of a material and to uses of such compositions. The invention further relates to a medical use of chitosan and to a pharmaceutical composition comprising the chitosan. The invention further relates to a method of treating a microbial infection and to an aqueous solution comprising chitosan. The invention moreover relates to a chitosan or a pharmaceutical composition comprising a chitosan for an epithelial cell growth stimulating treatment of a patient's tissue and to a method of stimulating the growth of epithelial cells. The invention also relates to a tissue dressing material.
    Type: Grant
    Filed: September 1, 2010
    Date of Patent: September 13, 2016
    Assignee: Medoderm GmbH
    Inventors: Karsten Henco, Thomas Freier, Rivelino Montenegro
  • Patent number: 9050395
    Abstract: A method for manufacturing a medical product comprising a hollow body (2), wherein at least part of a wall of the hollow body (2) is coated at least on the inside with a layer comprising a polymer; at least the part of at least the inside of the wall of the medical product is brought into contact with a mixture (6) of the polymer and the polymer is deposited from the mixture (6) on at least the part of the inside of the wall. And a medical product comprising a hollow body (2) with a wall consisting of one or more structural elements (16), at least a section of the wall being coated with a layer (15) comprising native chitosan, wherein both on the inside and the outside of the hollow body (2) at least some of the one or more structural elements (16) of the wall of the hollow body (2) are at least partly coated with the native chitosan layer (15). And a method for electrodepositing a polymer on an electrode from an acidic mixture of the polymer, wherein the mixture (6) comprises a multibasic acid.
    Type: Grant
    Filed: May 29, 2009
    Date of Patent: June 9, 2015
    Assignee: Medovent GmbH
    Inventors: Rivelino Montenegro, Thomas Freier
  • Patent number: 9034379
    Abstract: An article containing N-acylchitosan is manufactured by a process comprising the steps of providing a mixture containing chitosan and/or N-acylchitosan, and extruding the mixture to form an N-acylchitosan hydrogel. Alternatively, the process comprising the steps of providing a chitosan and/or N-acylchitosan hydrogel, and extruding the hydrogel. An article with a memorized shape is formed by fixing the N-acylchitosan hydrogel in a desired shape, and at least partially drying the fixed hydrogel. A patient is treated by injecting the N-acylchitosan hydrogel.
    Type: Grant
    Filed: March 26, 2013
    Date of Patent: May 19, 2015
    Inventor: Thomas Freier
  • Publication number: 20130276669
    Abstract: An article containing N-acylchitosan is manufactured by a process comprising the steps of providing a mixture containing chitosan and/or N-acylchitosan, and extruding the mixture to form an N-acylchitosan hydrogel. Alternatively, the process comprising the steps of providing a chitosan and/or N-acylchitosan hydrogel, and extruding the hydrogel. An article with a memorized shape is formed by fixing the N-acylchitosan hydrogel in a desired shape, and at least partially drying the fixed hydrogel. A patient is treated by injecting the N-acylchitosan hydrogel.
    Type: Application
    Filed: March 26, 2013
    Publication date: October 24, 2013
    Inventor: Thomas Freier
  • Patent number: 8414925
    Abstract: An article containing N-acylchitosan is manufactured by a process comprising the steps of providing a mixture containing chitosan and/or N-acylchitosan, and extruding the mixture to form an N-acylchitosan hydrogel. Alternatively, the process comprising the steps of providing a chitosan and/or N-acylchitosan hydrogel, and extruding the hydrogel. An article with a memorized shape is formed by fixing the N-acylchitosan hydrogel in a desired shape, and at least partially drying the fixed hydrogel. A patient is treated by injecting the N-acylchitosan hydrogel.
    Type: Grant
    Filed: October 11, 2006
    Date of Patent: April 9, 2013
    Inventor: Thomas Freier
  • Publication number: 20130041407
    Abstract: A fluid-swellable fiber in particular for the use as a surgical suture, the fiber comprising chitosan, the fiber's swelling ratio being less than 100%, and a fabric comprising the fiber. Moreover, a method of manufacturing from a chitosan-containing solution a fiber comprising chitosan, wherein during manufacture, the solution is brought into contact with a coagulation medium containing at least one organic solvent, a method of removing a fiber from a living organism, wherein the fiber is at least partly dissolved in a solvent applied from the outside, and a kit comprising a chitosan containing fiber and a solvent for at least partly dissolving the fiber.
    Type: Application
    Filed: February 2, 2010
    Publication date: February 14, 2013
    Applicant: MEDOVENT GMBH
    Inventors: Rivelino Montenegro, Thomas Freier
  • Publication number: 20120252755
    Abstract: The present invention relates to methods for disinfecting or decontaminating a material or for preventing an infection or contamination of a material. The invention further relates to compositions which are suitable for disinfecting a material or for preventing an infection or contamination of a material and to uses of such compositions. The invention further relates to a medical use of chitosan and to a pharmaceutical composition comprising the chitosan. The invention further relates to a method of treating a microbial infection and to an aqueous solution comprising chitosan. The invention moreover relates to a chitosan or a pharmaceutical composition comprising a chitosan for an epithelial cell growth stimulating treatment of a patient's tissue and to a method of stimulating the growth of epithelial cells. The invention also relates to a tissue dressing material.
    Type: Application
    Filed: September 1, 2010
    Publication date: October 4, 2012
    Applicant: MEDODERM GMBH
    Inventors: Karsten Henco, Thomas Freier, Rivelino Montenegro
  • Publication number: 20120232032
    Abstract: A chitosan for use in an antimicrobial treatment of a patient's tissue and a pharmaceutical composition comprising a chitosan for use in an antimicrobial treatment of a patient's tissue. A method of treating a microbial infection, the method comprising the step of administering to a patient an effective amount of a chitosan and an aqueous solution comprising chitosan. A chitosan or a pharmaceutical composition comprising a chitosan for use in an epithelial cell growth stimulating treatment of a patient's tissue. A method of stimulating the growth of epithelial cells the method comprising the step of administering to a patient or to an epithelial cells containing cell culture an effective amount of a chitosan or a pharmaceutical composition comprising chitosan. A tissue dressing material characterized in that it consists of chitosan or a chitosan comprising composition.
    Type: Application
    Filed: September 1, 2010
    Publication date: September 13, 2012
    Applicant: Medovent GmbH
    Inventors: Rivelino Montenegro, Thomas Freier, Karsten Henco