Abstract: The invention relates to an amplifier circuit (10a, 10b) for a two-wire interface, comprising a first current path (1), comprising a voltage-controlled current source (T1) having a gate (GT1), which is connected to an input connection (E1) of the amplifier circuit. A second current path (2) of the amplifier circuit comprises a voltage-controlled current source (T2), which is connected in series with the second resistor (R2). The first resistor (R1) and a parallel connection of the first and second current paths (1, 2) are connected in series between an output connection (A) and a reference voltage connection (B) of the amplifier circuit. The amplifier circuit (10a, 10b) makes it possible to adjust the gain and to provide a supply voltage and a useful signal over a common conducting track (L).

Abstract: The invention relates to a printed circuit board having an insulating support layer and a layer of conductive material applied thereto. In order to increase the flexibility of the printed circuit board, it is proposed that material from the support layer have been removed at at least one point on the printed circuit board on a side of the support layer which is opposite the layer of conductive material in order to form a straight groove which extends from one side of the printed circuit board to another side of the printed circuit board, so that the printed circuit board can be bent along the groove, wherein the material of the support layer which has remained in the region of the groove and/or the layer of conductive material in the region of the groove form(s) a bending edge.

Abstract: A method for ascertaining volume- or mass-flow of a medium in a pipeline, or measuring tube, of radius (r) via a sound entrainment method, wherein ultrasonic measuring signals are transmitted and/or received along a plurality of defined sound paths (m). During a calibration phase, successive, different flow profiles (v(r)) of a measured medium are established in the pipeline, or in the measuring tube, and wherein, for each flow profile (v(r)), a defined volume flow, or a defined mass flow, is ascertained, wherein, on the basis of measured values (vx(r1) . . . vx(rm)) ascertained in the separate measuring paths (m), each flow profile (v(r)) established in the pipeline, or in the measuring tube, is described by a characteristic parameter set (a1, . . . , an with n?N) and wherein, for each flow profile (V(r)), on the basis of the defined volume- or mass-flow and on the basis of the measured volume- or mass-flow, a flow-profile-dependent correction factor MF(a1, . . .

Abstract: A sensor amplifier arrangement includes an amplifier having a signal input to receive a sensor signal and a signal output to provide an amplified sensor signal, and a feedback path that couples the signal output to the signal input and provides a feedback current that is an attenuated signal of the amplified sensor signal and is inverted with respect to the sensor signal.

Abstract: The present invention is directed to method for analyzing multiple nucleic acid molecules of interest comprising in the steps of (i) providing a plurality of beads, characterized in that each bead comprises at least two sequence specific amplification primers, further characterized in that at least one of the primers is bound to the bead via a cleavable linker, (ii) capturing the nucleic acid molecules of interest from a sample, (iii) clonally isolating the plurality of beads, (iv) cleaving the at least one primer, (v) clonally amplifying the nucleic acid thereby creating multiple amplification products, and (vi) analyzing the amplification products.

Abstract: The invention relates to a lighting device for a motor vehicle. Said lighting device comprises a gas discharge lamp (1; 96) for emitting light, a starting device for providing a starting voltage for starting the gas discharge lamp (1; 96) and a control device for providing an input voltage for the starting device and an operating voltage for operation of the gas discharge lamp (1; 96). The control device is an integral part of the starting device. In order to come to grips with the problems associated with space and temperature with such lighting devices, the invention proposes that the combined starting and control device (5; 80) has a plug element (6) for connecting a vehicle power supply system voltage (7), the plug element (6) being in the form of a printed circuit board plug, which is formed by conductor tracks (21; 23) guided at an edge of a printed circuit board (20) of the starting and control device (5; 80).

Abstract: An integrated instrument for oligonucleotide synthesis and PCR, and a system and method thereof are disclosed. The integrated instrument is basically composed of two independent modules. The first module is a unit for chemical de novo synthesis of oligonucleotides such as oligonucleotide primers and/or oligonucleotide hybridization probes. The second module is a unit for performing an analytical polymerase chain reaction amplification in real time, i.e. a qPCR. The two modules are operatively linked to each other in such a way that a user can load a nucleic sample to be analyzed into the integrated instrument and perform a PCR reaction by programming the instrument without a previous external synthesis of oligonucleotide amplification primers.

Abstract: The invention relates to a lighting device for a motor vehicle. Said lighting device comprises a light source (1; 96) for emitting electromagnetic radiation, in particular light which is visible to the human eye, and a reflector (70; 81; 90) for focusing the emitted light. The light source (1; 96) is fastened on the reflector (70; 81; 90) at least indirectly in a defined position relative to a reflective surface of said reflector. In order firstly to make heat transfer from the reflector (70; 81; 90) to the light source (1; 96) more difficult and secondly to enable EMC shielding by virtue of an electrical contact between the light source (1; 96) and the reflector (70; 81; 90), the invention proposes that a material (72) with poor thermal conductivity is arranged between the reflector (70; 81; 90) and the light source (1; 96) for thermally insulating the light source (1; 96) from the reflector (70; 81; 90).

Abstract: A microphone amplifier comprises an input terminal (E100) for applying an input signal (IN), an output terminal (A100a) for outputting an output signal (OUT), and an additional output terminal (A100b) for outputting an additional output signal (VBIAS). The microphone amplifier also contains an amplifying circuit (10) for generating the output signal (OUT) by amplifying the input signal (IN), wherein the amplifying circuit (10) is connected between the input terminal (E100) and the output terminal (A100a), and a voltage generator (30) for generating the additional output signal (VBIAS). A supply voltage terminal (V30) of the voltage generator (30) is connected to the output terminal (A100a) of the microphone amplifier. Since the amplifying circuit (10) makes available a supply voltage (V) for the voltage generator (30), the microphone amplifier can be operated without a separate supply voltage terminal.

Abstract: Disclosed is a process for clonal pre-amplification of a nucleic acid involving the steps of (i) providing a plurality of different nucleic acid molecules (b) attaching adaptor sequences to the 3? ends and 5? ends of the nucleic acid molecules (c) preparing a water in oil emulsion wherein the majority of water droplets comprises one or none member of the plurality of different nucleic acid molecules (d) clonally amplifying the plurality of different nucleic acid molecules. In particular, the different nucleic acid molecules are mRNA molecules.

Abstract: An amplifier arrangement has an amplifier (3) with a signal input (31), a feedback input (32) and a signal output (33). A first coupling path (FB1), which has a first impedance element (R1), connects the feedback input (32) to the signal output (33). A second coupling path (FB2) has a filter device (4), a buffer circuit (5) and a second impedance element (R2) connected in series, and connects the feedback input (32) to the signal output (33) or to the signal input (31).

Abstract: An integrated instrument for oligonucleotide synthesis and PCR, and a system and method thereof are disclosed. The integrated instrument is basically composed of two independent modules. The first module is a unit for chemical de novo synthesis of oligonucleotides such as oligonucleotide primers and/or oligonucleotide hybridization probes. The second module is a unit for performing an analytical polymerase chain reaction amplification in real time, i.e. a qPCR. The two modules are operatively linked to each other in such a way that a user can load a nucleic sample to be analyzed into the integrated instrument and perform a PCR reaction by programming the instrument without a previous external synthesis of oligonucleotide amplification primers.

Abstract: A method for system- and/or process-monitoring in the case of an ultrasound flow measuring device having a plurality of measuring channels, wherein a medium flows though a pipeline or measuring tube in the direction of a longitudinal axis of the pipeline or measuring tube. Ultrasonic measuring signals are coupled into the pipeline or measuring tube and coupled out of the pipeline or measuring tube in such a way that they travel through the medium along different sound paths. Following passage through the pipeline or measuring tube, the ultrasonic measuring signals are detected in the individual measuring channels, wherein at least one actual quantity describing the ultrasonic measuring signal of each measuring channel is ascertained. The actual quantity is compared with a desired quantity captured under predetermined system- or process-conditions, and a report is output in the case of a difference between the ascertained, actual quantity and the captured, desired quantity.

Abstract: The invention relates to an eye protection cap to protect an eye of a person to be treated against electromagnetic radiation, in particular against laser radiation. The eye protection cap comprises a dimensionally stable shaped body, which has a free edge for adjacent arrangement in relation to the person to be treated, limits a hollow shaped body interior, is formed from a silicone material and has a self-holding region for independent holding on the person to be treated.

Abstract: The invention relates to a lighting device for a motor vehicle. Said lighting device comprises a gas discharge lamp (1; 96) for emitting light, a starting device for providing a starting voltage for starting the gas discharge lamp (1; 96) and a control device for providing an input voltage for the starting device and an operating voltage for operation of the gas discharge lamp (1; 96). The control device is an integral part of the starting device. In order to come to grips with the problems associated with space and temperature with such lighting devices, the invention proposes that the combined starting and control device (5; 80) has a plug element (6) for connecting a vehicle power supply system voltage (7), the plug element (6) being in the form of a printed circuit board plug, which is formed by conductor tracks (21; 23) guided at an edge of a printed circuit board (20) of the starting and control device (5; 80).

Abstract: The invention relates to a printed circuit board (60) having an insulating support layer (61) and a layer (62) of conductive material applied thereto. In order to increase the flexibility of the printed circuit board (60), it is proposed that material from the support layer (61) have been removed at least one point on the printed circuit board (60) on a side of the support layer (61) which is opposite the layer (62) of conductive material in order to form a straight groove (63) which extends from one side of the printed circuit board (60) to another side of the printed circuit board (60), so that the printed circuit board (60) can be bent along the groove (63), wherein the material of the support layer (61) which has remained in the region of the groove (63) and/or the layer (62) of conductive material in the region of the groove (63) form(s) a bending edge (64).

Abstract: The invention relates to a lighting device for a motor vehicle. Said lighting device comprises a light source (1; 96) for emitting electromagnetic radiation, in particular light which is visible to the human eye, and a reflector (70; 81; 90) for focusing the emitted light. The light source (1; 96) is fastened on the reflector (70; 81; 90) at least indirectly in a defined position relative to a reflective surface of said reflector. In order firstly to make heat transfer from the reflector (70; 81; 90) to the light source (1; 96) more difficult and secondly to enable EMC shielding by virtue of an electrical contact between the light source (1; 96) and the reflector (70; 81; 90), the invention proposes that a material (72) with poor thermal conductivity is arranged between the reflector (70; 81; 90) and the light source (1; 96) for thermally insulating the light source (1; 96) from the reflector (70; 81; 90).

Abstract: The present invention is directed to method for analyzing multiple nucleic acid molecules of interest comprising in the steps of (i) providing a plurality of beads, characterized in that each bead comprises at least two sequence specific amplification primers, further characterized in that at least one of the primers is bound to the bead via a cleavable linker, (ii) capturing the nucleic acid molecules of interest from a sample, (iii) clonally isolating the plurality of beads, (iv) cleaving the at least one primer, (v) clonally amplifying the nucleic acid thereby creating multiple amplification products, and (vi) analyzing the amplification products.

Abstract: The present invention provides a solid support which is preferably a bead comprising at least two sequence specific amplification primers wherein at least one primer is bound to the support with an inducible cleavable linker. The present invention also provides various method for preparing a solid support comprising at least two sequence specific primers, further characterized in that at least one of the primers is cleavable.

Abstract: The current invention restates substituted nitroindole nucleosides as both terminal as well as internal building blocks of labeled oligonucleotide probes for the detection, analysis and quantitation of nucleic acids. The substituent comprises a linker and a detectable group or a linker and a reactive group for post synthesis coupling. These modified nucleosides grant access to a wide application area. These new substituted nitroindole nucleosides can be used as labeling reagents for the facile preparation of, e.g., optimized hybridization probes, simple probes, TAQMAN-probes or molecular beacon probes.