Abstract: The invention relates to a method of investigating by mass spectrometry the genetic material deoxyribonucleic acid (DNA) replicated by polymerase chain reaction (PCR), for the identification of known mutations and polymorphisms; it particularly relates to the analysis of single nucleotide polymorphisms (SNPs) by matrix assisted laser desorption and ionization (MALDI). The invention consists of using a set of nucleoside triphosphates for the selective PCR replication of the DNA in which one or more of the nucleoside triphosphates have been made much heavier by attaching a chemical group, but in such a way that the replication is not disturbed by the polymerase. In this way a single nucleotide polymorphism in DNA pieces with a length of about 40 to 50 bases can very easily be made visible by mass spectrometry without any further manipulation.

Abstract: Motor/gear unit for adjustment devices in motor vehicles with a base plate 2 supporting the motor/gear unit and able to fit in an opening 10 of a wall 1 separating a wet space A from a dry space B. The output 5 of gear is mounted on the wet space side A and at least the elements for the electrical contact of the electric motor 6 and where applicable a switch and/or an electronic control device 7 are mounted on the dry space side B. A seal 3 enclosing the opening 10 is mounted between the wall 1 and the base plate 2. The base plate 2 forms one unit at least with a part of the gear housing 20 and is mounted on the wall 1 from the wet space side A.