Patents by Inventor Thomas G. Gant

Thomas G. Gant has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PIPERAZINE MODULATORS OF NK-1 RECEPTORS
    Publication number: 20100137332
    Abstract: The present invention relates to new piperazine modulators of NK-1 receptors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: December 3, 2009
    Publication date: June 3, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Manouchehr M. Shahbaz
  • PHTHALAZINONE MODULATORS OF H1 RECEPTORS AND/OR LTC4 RECEPTORS
    Publication number: 20100137268
    Abstract: The present invention relates to new phthalazinone modulators of H1 receptor activity and/or modulators of LTC4 production, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: December 3, 2009
    Publication date: June 3, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventor: Thomas G. Gant
  • PREPARATION AND UTILITY OF HMG-COA REDUCTASE INHIBITORS
    Publication number: 20100137244
    Abstract: Chemical syntheses and medical uses of novel modulators of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase and diastereomeric mixtures of isomers, individual diastereomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, the chemical synthesis thereof, and the medical use of such compounds for the treatment and/or management of hypercholesterolemia, dyslipidemia, coronary artery disease, atherosclerosis, metabolic syndrome, a hyperproliferative disease such as colorectal cancer, prostate cancer, and melanoma, a neurodegenerative disease such as cerebral ischemia, Alzheimer's disease, and Parkinson's disease are described.
    Type: Application
    Filed: July 12, 2007
    Publication date: June 3, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • SULFONYLUREA INHIBITORS OF ATP-SENSITIVE POTASSIUM CHANNELS
    Publication number: 20100130615
    Abstract: The present invention relates to new sulfonylurea inhibitors of ATP-sensitive potassium channels, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: November 19, 2009
    Publication date: May 27, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventor: Thomas G. Gant
  • PYRAZOLE CARBOXAMIDE INHIBITORS OF FACTOR XA
    Publication number: 20100130543
    Abstract: The present invention relates to new pyrazole carboxamide inhibitors of factor Xa, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: September 14, 2009
    Publication date: May 27, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Manoucherhr M. Shahbaz
  • INDOLINONE MODULATORS OF DOPAMINE RECEPTOR
    Publication number: 20100130582
    Abstract: The present invention relates to new indolinone modulators of dopamine receptor, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: November 24, 2009
    Publication date: May 27, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • PHENYLALANINE AMIDE INHIBITORS OF ATP-SENSITIVE POTASSIUM CHANNELS
    Publication number: 20100129311
    Abstract: The present invention relates to new phenylalanine amide inhibitors of ATP-sensitive potassium channels, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: November 23, 2009
    Publication date: May 27, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventor: Thomas G. Gant
  • ETHANOLAMINE MODULATORS OF NMDA RECEPTOR AND MUSCARINIC ACETYLCHOLINE RECEPTOR
    Publication number: 20100130617
    Abstract: The present invention relates to new ethanolamine modulators of NMDA receptors and/or muscarinic acetylcholine receptors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: November 23, 2009
    Publication date: May 27, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • THIAZOLE INHIBITORS OF CYCLOOXYGENASE
    Publication number: 20100129366
    Abstract: The present invention relates to new thiazole inhibitors of cyclooxygenase, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: November 19, 2009
    Publication date: May 27, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Manouchehr Shahbaz
  • ADAMANTANE MODULATORS OF NMDA RECEPTOR AND/OR 5HT3 RECEPTOR
    Publication number: 20100130528
    Abstract: The present invention relates to new adamantane modulators of NMDA receptors and/or 5HT3 receptors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: November 23, 2009
    Publication date: May 27, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventor: Thomas G. Gant
  • BENZOQUINOLINE INHIBITORS OF VESICULAR MONOAMINE TRANSPORTER 2
    Publication number: 20100130480
    Abstract: The present invention relates to new benzoquinoline inhibitors of vesicular monoamine transporter 2 (VMAT2), pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: September 18, 2009
    Publication date: May 27, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Manoucherhr M. Shahbaz
  • PYRIDOINDOLE MODULATORS OF NMDA RECEPTOR AND ACETYLCHOLINESTERASE
    Publication number: 20100125085
    Abstract: The present invention relates to new pyridoindole modulators of NMDA receptors, AMPA receptors, and/or L-type calcium channels, and/or inhibitors of acetylcholinesterase, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: November 16, 2009
    Publication date: May 20, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Manouchehr M. Shahbaz
  • PYRROLIDINYL MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTORS
    Publication number: 20100125094
    Abstract: The present invention relates to new pyrrolidinyl modulating nicotinic acetylcholine receptor compounds, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: November 16, 2009
    Publication date: May 20, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Manouchehr M. Shahbaz, Craig Hodulik
  • SULFONAMIDE INHIBITORS OF CARBONIC ANHYDRASE II
    Publication number: 20100125067
    Abstract: The present invention relates to new sulfonamide inhibitors of carbonic anhydrase II, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: November 19, 2009
    Publication date: May 20, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventor: Thomas G. Gant
  • HYDROXYADAMANTYL INHIBITORS OF DIPEPTIDYLPEPTIDASE IV
    Publication number: 20100124541
    Abstract: The present invention relates to new hydroxyadamantyl inhibitors of dipeptidylpeptidase IV activity, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: November 17, 2009
    Publication date: May 20, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Manouchehr M. Shahbaz
  • AMIDE INHIBITORS OF RENIN
    Publication number: 20100124550
    Abstract: The present invention relates to new amide inhibitors of renin, pharmaceutical compositions thereof, and methods of use thereof
    Type: Application
    Filed: November 20, 2009
    Publication date: May 20, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Manouchehr M. Shahbaz
  • BENZISOXAZOLE MODULATORS OF D2 RECEPTOR AND/OR 5-HT2A RECEPTOR
    Publication number: 20100119624
    Abstract: The present invention relates to new benzisoxazole modulators of D2 receptors and/or 5-HT2A receptors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: September 17, 2009
    Publication date: May 13, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • 3H-BENZOOXAZOL-2-ONE MODULATORS OF D2 RECEPTOR AND/OR 5-HT1A RECEPTOR
    Publication number: 20100119622
    Abstract: The present invention relates to new 3H-benzooxazol-2-one modulators of D2 receptors and/or 5-HT1A receptors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: September 15, 2009
    Publication date: May 13, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • PHENYLACETIC ACID INHIBITORS OF CYCLOOXYGENASE
    Publication number: 20100119508
    Abstract: The present invention relates to new phenylacetic acid inhibitors of cyclooxygenase activity, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: November 11, 2009
    Publication date: May 13, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Manoucherhr M. Shahbaz
  • IMIDAZOLYL MODULATORS OF 5-HT3 RECEPTORS
    Publication number: 20100119623
    Abstract: The present invention relates to new imidazolyl modulators of 5-HT3 receptors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: September 16, 2009
    Publication date: May 13, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar