Patents by Inventor Thomas G. Gant

Thomas G. Gant has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • STEROID MODULATORS OF GLUCOCORTICOID RECEPTOR
    Publication number: 20100120733
    Abstract: The present invention relates to new steroid modulators of glucocorticoid receptor activity, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: November 6, 2009
    Publication date: May 13, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Manouchehr M. Shahbaz
  • BENZOIC ACID INHIBITORS OF ATP-SENSITIVE POTASSIUM CHANNELS
    Publication number: 20100120861
    Abstract: The present invention relates to new benzoic acid inhibitors of ATP-sensitive potassium channel activity, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: November 12, 2009
    Publication date: May 13, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • PHENOTHIAZINE MODULATORS OF H1 RECEPTORS
    Publication number: 20100120756
    Abstract: The present invention relates to new phenothiazine modulators of H1 receptors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: September 17, 2009
    Publication date: May 13, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • ACETAMIDOPROPANE MODULATORS OF NMDA RECEPTORS
    Publication number: 20100120744
    Abstract: The present invention relates to new acetamidopropane modulators of NMDA receptor, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: September 18, 2009
    Publication date: May 13, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventor: Thomas G. Gant
  • BUTYLAMMONIUM MODULATORS OF FATTY ACID TRANSPORT
    Publication number: 20100120917
    Abstract: The present invention relates to new butylammonium modulators of fatty acid transport, and/or removal of toxic acyl-CoA compounds, pharmaceutical compositions thereof, and methods of use thereof
    Type: Application
    Filed: November 10, 2009
    Publication date: May 13, 2010
    Applicant: Auspex Pharmaceuticals, Inc.
    Inventors: Thomas G. Gant, Manouchehr Shahbaz, Craig Hodulik
  • PREPARATION AND UTILITY OF SUBSTITUTED IMIDAZOPYRIDINE COMPOUNDS WITH HYPNOTIC EFFECTS
    Publication number: 20100121067
    Abstract: The present disclosure is directed to modulators of GABAA receptors and pharmaceutically acceptable salts and prodrugs thereof, the chemical synthesis thereof, and the medical use of such compounds for the treatment and/or management of sleep disorders and/or for providing a patient in need with a hypnotic, anxiolytic or anti-convulsive effect are described.
    Type: Application
    Filed: September 1, 2009
    Publication date: May 13, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • METHYLINDAZOLE MODULATORS OF 5-HT3 RECEPTORS
    Publication number: 20100113405
    Abstract: The present invention relates to new methylindazole modulators of 5-HT3 receptor activity, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: November 4, 2009
    Publication date: May 6, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • INDOLONE MODULATORS OF 5-HT3 RECEPTOR
    Publication number: 20100113478
    Abstract: The present invention relates to new indolone modulators of 5-HT3 receptor, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: September 11, 2009
    Publication date: May 6, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • TRIAZOLE INHIBITORS OF AROMATASE
    Publication number: 20100111901
    Abstract: The present invention relates to new triazole modulators of aromatase activity, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: November 3, 2009
    Publication date: May 6, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar, Manouchehr M. Shahbaz
  • PIPERIDINE MODULATORS OF VMAT2
    Publication number: 20100113496
    Abstract: The present invention relates to new piperidine modulators of VMAT2, nicotinic acetylcholine receptors, and/or ?-opioid receptors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: September 22, 2009
    Publication date: May 6, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventor: Thomas G. Gant
  • DIMETHYLPHENOXY MODULATORS OF VIRAL PROTEASE ACTIVITY AND/OR PARASITIC ENZYME ACTIVITY
    Publication number: 20100113359
    Abstract: The present invention relates to new dimethylphenoxy inhibitors of viral protease or parasitic enzymes, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: November 5, 2009
    Publication date: May 6, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • PHENOTHIAZINE MODULATORS OF D2 RECEPTORS AND 5-HT2 RECEPTORS
    Publication number: 20100113432
    Abstract: The present invention relates to new phenothiazine modulators of D2 receptor activity and/or 5-HT2 receptor activity, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: November 4, 2009
    Publication date: May 6, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • AMINOPROPANOL MODULATORS OF BETA-1 ADRENERGIC RECEPTOR
    Publication number: 20100113606
    Abstract: The present invention relates to new aminopropanol modulators of beta-1 adrenergic receptor activity, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: November 3, 2009
    Publication date: May 6, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • N-METHYL PIPERAZINE MODULATORS OF H1 RECEPTOR
    Publication number: 20100113431
    Abstract: The present invention relates to new N-methyl piperazine modulators of H1 receptor activity, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: November 4, 2009
    Publication date: May 6, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Manouchehr M. Shahbaz
  • PREPARATION AND UTILITY OF SUBSTITUTED IMIDAZOPYRIDINE COMPOUNDS WITH HYPNOTIC EFFECTS
    Publication number: 20100105720
    Abstract: The present disclosure is directed to modulators of GABAA receptors and pharmaceutically acceptable salts and prodrugs thereof, the chemical synthesis thereof, and the medical use of such compounds for the treatment and/or management of sleep disorders and/or for providing a patient in need with a hypnotic, anxiolytic or anti-convulsive effect are described.
    Type: Application
    Filed: September 1, 2009
    Publication date: April 29, 2010
    Applicant: Auspex Pharmaceuticals, Inc.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • SUBSTITUTED BENZAMIDE MODULATORS OF DOPAMINE RECEPTOR
    Publication number: 20100105755
    Abstract: The present invention relates to new substituted benzamide modulators of dopamine receptor, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: September 11, 2009
    Publication date: April 29, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • ISOQUINOLINONE MODULATORS OF 5-HT3 RECEPTORS
    Publication number: 20100099701
    Abstract: The present invention relates to new isoquinolinone modulators of 5-HT3 receptors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: October 19, 2009
    Publication date: April 22, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventor: Thomas G. Gant
  • PHENOTHIAZINE MODULATORS OF H1 RECEPTOR AND D2 RECEPTOR
    Publication number: 20100099666
    Abstract: The present invention relates to new phenothiazine modulators of H1 receptors and/or D2 receptors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: October 20, 2009
    Publication date: April 22, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • PYRIDINE SULFONAMIDE MODULATORS OF ENDOTHELIN-A RECEPTOR
    Publication number: 20100093758
    Abstract: The present invention relates to new pyridine sulfonamide modulators of endothelin-A receptor, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: July 23, 2009
    Publication date: April 15, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • TROPINE MODULATORS OF 5-HT3 RECEPTOR
    Publication number: 20100087364
    Abstract: The present invention relates to new tropine modulators of 5-HT3 receptor, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: October 7, 2009
    Publication date: April 8, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventor: Thomas G. Gant