Patents by Inventor Thomas H. King

Thomas H. King has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODIFIED YEAST-BRACHYURY IMMUNOTHERAPEUTIC COMPOSITIONS
    Publication number: 20180214525
    Abstract: Disclosed are improved yeast-based immunotherapeutic compositions comprising modified Brachyury antigens, and methods for the prevention and/or treatment of cancers characterized by the expression or overexpression of Brachyury.
    Type: Application
    Filed: August 1, 2016
    Publication date: August 2, 2018
    Inventors: Thomas H. KING, Zhimin GUO, Jeffrey SCHLOM, Claudia PALENA
  • COMPOSITIONS AND METHODS FOR THE TREATMENT OR PREVENTION OF HUMAN IMMUNODEFICIENCY VIRUS INFECTION
    Publication number: 20180177865
    Abstract: Disclosed are yeast-based immunotherapeutic compositions, human immunodeficiency virus (HIV) antigens, and fusion proteins for the treatment and/or prevention of HIV infection and symptoms thereof, as well as methods of using the yeast-based immunotherapeutic compositions, HIV antigens, and fusion proteins for the prophylactic and/or therapeutic treatment of HIV and/or symptoms thereof.
    Type: Application
    Filed: September 7, 2017
    Publication date: June 28, 2018
    Inventors: Thomas H. KING, David APELIAN
  • Yeast-based compositions and methods for the treatment or prevention of hepatitis delta virus infection
    Patent number: 9987352
    Abstract: Disclosed are immunotherapeutic compositions and methods for preventing and/or treating hepatitis delta virus (HDV) infection, including yeast-based HDV immunotherapeutic compositions and methods of use of such compositions to prevent and/or treat HDV infection and symptoms and sequela thereof.
    Type: Grant
    Filed: January 17, 2017
    Date of Patent: June 5, 2018
    Assignee: GlobeImmune, Inc.
    Inventors: Thomas H. King, David Apelian
  • Compositions and methods for the treatment or prevention of hepatitis B virus infection
    Patent number: 9943591
    Abstract: Disclosed are yeast-based immunotherapeutic compositions, hepatitis B virus (HBV) antigens, and fusion proteins for the treatment and/or prevention of HBV infection and symptoms thereof, as well as methods of using the yeast-based immunotherapeutic compositions, HBV antigens, and fusion proteins for the prophylactic and/or therapeutic treatment of HBV and/or symptoms thereof.
    Type: Grant
    Filed: July 18, 2016
    Date of Patent: April 17, 2018
    Assignee: GlobeImmune, Inc.
    Inventors: David Apelian, Thomas H. King, Zhimin Guo, Claire Coeshott
  • Compositions and methods for the treatment or prevention of human immunodeficiency virus infection
    Patent number: 9782473
    Abstract: Disclosed are yeast-based immunotherapeutic compositions, human immunodeficiency virus (HIV) antigens, and fusion proteins for the treatment and/or prevention of HIV infection and symptoms thereof, as well as methods of using the yeast-based immunotherapeutic compositions, HIV antigens, and fusion proteins for the prophylactic and/or therapeutic treatment of HIV and/or symptoms thereof.
    Type: Grant
    Filed: March 26, 2014
    Date of Patent: October 10, 2017
    Assignee: GLOBEIMMUNE, INC.
    Inventors: Thomas H. King, David Apelian
  • YEAST-BASED COMPOSITIONS AND METHODS FOR THE TREATMENT OR PREVENTION OF HEPATITIS DELTA VIRUS INFECTION
    Publication number: 20170182153
    Abstract: Disclosed are immunotherapeutic compositions and methods for preventing and/or treating hepatitis delta virus (HDV) infection, including yeast-based HDV immunotherapeutic compositions and methods of use of such compositions to prevent and/or treat HDV infection and symptoms and sequela thereof.
    Type: Application
    Filed: January 17, 2017
    Publication date: June 29, 2017
    Inventors: Thomas H. King, David Apelian
  • Yeast-based compositions and methods for the treatment or prevention of hepatitis delta virus infection
    Patent number: 9579377
    Abstract: Disclosed are immunotherapeutic compositions and methods for preventing and/or treating hepatitis delta virus (HDV) infection, including yeast-based HDV immunotherapeutic compositions and methods of use of such compositions to prevent and/or treat HDV infection and symptoms and sequela thereof.
    Type: Grant
    Filed: June 14, 2012
    Date of Patent: February 28, 2017
    Assignee: GlobeImmune, Inc.
    Inventors: Thomas H. King, David Apelian
  • YEAST-BASED IMMUNOTHERAPY AND TYPE I INTERFERON SENSITIVITY
    Publication number: 20170035867
    Abstract: Disclosed are methods of treating individuals with yeast-based immunotherapy who have been preselected as being sensitive to type I interferons, as well as methods for selecting individuals for treatment with yeast-based immunotherapeutic compositions and methods for enhancing or improving an individual's response to yeast-based immunotherapy, based on the individual's sensitivity to type 1 interferons (T1IFNs).
    Type: Application
    Filed: April 10, 2015
    Publication date: February 9, 2017
    Inventors: Donald BELLGRAU, Thomas H. KING
  • Compositions and Methods for the Treatment or Prevention of Hepatitis B Virus Infection
    Publication number: 20170000879
    Abstract: Disclosed are yeast-based immunotherapeutic compositions, hepatitis B virus (HBV) antigens, and fusion proteins for the treatment and/or prevention of HBV infection and symptoms thereof, as well as methods of using the yeast-based immunotherapeutic compositions, HBV antigens, and fusion proteins for the prophylactic and/or therapeutic treatment of HBV and/or symptoms thereof.
    Type: Application
    Filed: July 18, 2016
    Publication date: January 5, 2017
    Inventors: David Apelian, Thomas H. King, Zhimin Guo, Claire Coeshott
  • Compositions and methods for the treatment or prevention of hepatitis B virus infection
    Patent number: 9428556
    Abstract: Disclosed are yeast-based immunotherapeutic compositions, hepatitis B virus (HBV) antigens, and fusion proteins for the treatment and/or prevention of HBV infection and symptoms thereof, as well as methods of using the yeast-based immunotherapeutic compositions, HBV antigens, and fusion proteins for the prophylactic and/or therapeutic treatment of HBV and/or symptoms thereof.
    Type: Grant
    Filed: January 7, 2015
    Date of Patent: August 30, 2016
    Assignee: GlobeImmune, Inc.
    Inventors: David Apelian, Thomas H. King, Zhimin Guo, Claire Coeshott
  • COMPOSITIONS AND METHODS FOR THE TREATMENT OR PREVENTION OF TUBERCULOSIS
    Publication number: 20160213767
    Abstract: Disclosed are yeast-based immunotherapeutic compositions and fusion proteins for the treatment and/or prevention of TB infection and symptoms thereof, as well as methods of using the yeast-based immunotherapeutic compositions and fusion proteins for the prophylactic and/or therapeutic treatment of TB and/or symptoms thereof.
    Type: Application
    Filed: August 29, 2014
    Publication date: July 28, 2016
    Inventors: Thomas H. KING, Zhimin GUO, Ian M. ORME
  • Yeast-based therapeutic for chronic hepatitis B infection
    Patent number: 9290547
    Abstract: Disclosed are yeast-based immunotherapeutic compositions, hepatitis B virus (HBV) antigens, and fusion proteins for the treatment and/or prevention of HBV infection and symptoms thereof, as well as methods of using the yeast-based immunotherapeutic compositions, HBV antigens, and fusion proteins for the prophylactic and/or therapeutic treatment of HBV and/or symptoms thereof.
    Type: Grant
    Filed: September 23, 2014
    Date of Patent: March 22, 2016
    Assignee: GlobeImmune, Inc.
    Inventors: David Apelian, Thomas H. King, Zhimin Guo, Claire Coeshott
  • COMPOSITIONS AND METHODS FOR THE TREATMENT OR PREVENTION OF HUMAN IMMUNODEFICIENCY VIRUS INFECTION
    Publication number: 20160045592
    Abstract: Disclosed are yeast-based immunotherapeutic compositions, human immunodeficiency virus (HIV) antigens, and fusion proteins for the treatment and/or prevention of HIV infection and symptoms thereof, as well as methods of using the yeast-based immunotherapeutic compositions, HIV antigens, and fusion proteins for the prophylactic and/or therapeutic treatment of HIV and/or symptoms thereof.
    Type: Application
    Filed: March 26, 2014
    Publication date: February 18, 2016
    Inventors: Thomas H. KING, David APELIAN
  • Compositions and Methods for the Treatment or Prevention of Hepatitis B Virus Infection
    Publication number: 20150191509
    Abstract: Disclosed are yeast-based immunotherapeutic compositions, hepatitis B virus (HBV) antigens, and fusion proteins for the treatment and/or prevention of HBV infection and symptoms thereof, as well as methods of using the yeast-based immunotherapeutic compositions, HBV antigens, and fusion proteins for the prophylactic and/or therapeutic treatment of HBV and/or symptoms thereof.
    Type: Application
    Filed: January 7, 2015
    Publication date: July 9, 2015
    Inventors: David Apelian, Thomas H. King, Zhimin Guo, Claire Coeshott
  • YEAST-BASED THERAPEUTIC FOR CHRONIC HEPATITIS B INFECTION
    Publication number: 20150110828
    Abstract: Disclosed are yeast-based immunotherapeutic compositions, hepatitis B virus (HBV) antigens, and fusion proteins for the treatment and/or prevention of HBV infection and symptoms thereof, as well as methods of using the yeast-based immunotherapeutic compositions, HBV antigens, and fusion proteins for the prophylactic and/or therapeutic treatment of HBV and/or symptoms thereof.
    Type: Application
    Filed: September 23, 2014
    Publication date: April 23, 2015
    Inventors: David APELIAN, Thomas H. KING, Zhimin GUO, Claire COESHOTT
  • Compositions and methods for the treatment or prevention of hepatitis B virus infection
    Patent number: 8961988
    Abstract: Disclosed are yeast-based immunotherapeutic compositions, hepatitis B virus (HBV) antigens, and fusion proteins for the treatment and/or prevention of HBV infection and symptoms thereof, as well as methods of using the yeast-based immunotherapeutic compositions, HBV antigens, and fusion proteins for the prophylactic and/or therapeutic treatment of HBV and/or symptoms thereof.
    Type: Grant
    Filed: February 19, 2014
    Date of Patent: February 24, 2015
    Assignee: GlobeImmune, Inc.
    Inventors: David Apelian, Thomas H. King, Zhimin Guo, Claire Coeshott
  • Yeast-based therapeutic for chronic hepatitis B infection
    Patent number: 8877205
    Abstract: Disclosed are yeast-based immunotherapeutic compositions, hepatitis B virus (HBV) antigens, and fusion proteins for the treatment and/or prevention of HBV infection and symptoms thereof, as well as methods of using the yeast-based immunotherapeutic compositions, HBV antigens, and fusion proteins for the prophylactic and/or therapeutic treatment of HBV and/or symptoms thereof.
    Type: Grant
    Filed: February 9, 2012
    Date of Patent: November 4, 2014
    Assignee: GlobeImmune, Inc.
    Inventors: David Apelian, Thomas H. King, Zhimin Guo, Claire Coeshott
  • Compositions and Methods for the Treatment or Prevention of Hepatitis B Virus Infection
    Publication number: 20140286984
    Abstract: Disclosed are yeast-based immunotherapeutic compositions, hepatitis B virus (HBV) antigens, and fusion proteins for the treatment and/or prevention of HBV infection and symptoms thereof, as well as methods of using the yeast-based immunotherapeutic compositions, HBV antigens, and fusion proteins for the prophylactic and/or therapeutic treatment of HBV and/or symptoms thereof.
    Type: Application
    Filed: February 19, 2014
    Publication date: September 25, 2014
    Applicant: Globelmmune, Inc.
    Inventors: David Apelian, Thomas H. King, Zhimin Guo, Claire Coeshott
  • Yeast-based therapeutic for chronic hepatitis C infection
    Patent number: 8821892
    Abstract: Disclosed are compositions, including vaccines, and methods for vaccinating an animal against hepatitis C virus (HCV) and for treating or preventing hepatitis C viral infection in an animal. The invention includes a variety of novel HCV fusion proteins that can be used directly as a vaccine or in conjunction with a yeast-based vaccine vehicle to elicit an immune response against HCV in an animal. The invention also includes the use of the HCV fusion gene and protein described herein in any diagnostic or therapeutic protocol for the detection and/or treatment or prevention of HCV infection.
    Type: Grant
    Filed: January 8, 2013
    Date of Patent: September 2, 2014
    Assignee: GlobeImmune, Inc.
    Inventors: Richard C. Duke, Alex Franzusoff, Aurelia Haller, Thomas H. King
  • YEAST-BASED COMPOSITIONS AND METHODS FOR THE TREATMENT OR PREVENTION OF HEPATITIS DELTA VIRUS INFECTION
    Publication number: 20140193362
    Abstract: Disclosed are immunotherapeutic compositions and methods for preventing and/or treating hepatitis delta virus (HDV) infection, including yeast-based HDV immunotherapeutic compositions and methods of use of such compositions to prevent and/or treat HDV infection and symptoms and sequela thereof.
    Type: Application
    Filed: June 14, 2012
    Publication date: July 10, 2014
    Applicant: GLOBEIMMUNE, INC.
    Inventors: Thomas H. King, David Apellan