Patents by Inventor Thomas Hall

Thomas Hall has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Systems and methods for rapid identification of nucleic acid variants
    Patent number: 8551738
    Abstract: There is a need for nucleic acid analysis which is both specific and rapid, and in which no nucleic acid sequencing is required. The present invention addresses this need, among others by providing a method of nucleic acid amplification of overlapping sub-segments of a nucleic acid followed by molecular mass measurement of resulting amplification products by mass spectrometry, and determination of the base compositions of the amplification products.
    Type: Grant
    Filed: November 11, 2009
    Date of Patent: October 8, 2013
    Assignee: Ibis Biosciences, Inc.
    Inventors: David J. Ecker, Steven A. Hofstadler, Thomas A. Hall, Kristin Sannes-Lowery
  • Methods for identification of sepsis-causing bacteria
    Patent number: 8546082
    Abstract: The present invention provides compositions, kits and methods for rapid identification and quantification of sepsis-causing bacteria by molecular mass and base composition analysis.
    Type: Grant
    Filed: May 25, 2007
    Date of Patent: October 1, 2013
    Assignee: Ibis Biosciences, Inc.
    Inventors: Thomas A. Hall, Rangarajan Sampath, Vanessa Harpin, Steven A. Hofstadler, Yun Jiang
  • COMPOSITIONS FOR USE IN IDENTIFICATION OF ORTHOPOXVIRUSES
    Publication number: 20130236884
    Abstract: Oligonucleotide primers and compositions and kits containing the same for rapid identification of orthopoxviruses by amplification of a segment of viral nucleic acid followed by molecular mass analysis are provided.
    Type: Application
    Filed: May 7, 2013
    Publication date: September 12, 2013
    Applicant: IBIS BIOSCIENCES, INC.
    Inventors: Rangarajan Sampath, Thomas A. Hall, David J. Ecker, Steven A. Hofstadler
  • Methods for rapid forensic analysis of mitochondrial DNA
    Patent number: 8407010
    Abstract: The present invention provides methods for rapid forensic analysis of mitochondrial DNA by amplification of a segment of mitochondrial DNA containing restriction sites, digesting the mitochondrial DNA segments with restriction enzymes, determining the molecular masses of the restriction fragments and comparing the molecular masses with the molecular masses of theoretical restriction digests of known mitochondrial DNA sequences stored in a database.
    Type: Grant
    Filed: March 17, 2008
    Date of Patent: March 26, 2013
    Assignee: Ibis Biosciences, Inc.
    Inventors: Steven A. Hofstadler, Thomas A. Hall, David J. Ecker, Lawrence B. Blyn, Mark W. Eshoo, Vivek Samant, Neill White
  • Compositions for use in identification of bacteria
    Patent number: 8394945
    Abstract: The present invention provides compositions, kits and methods for rapid identification and quantification of bacteria by molecular mass and base composition analysis.
    Type: Grant
    Filed: March 7, 2007
    Date of Patent: March 12, 2013
    Assignee: Ibis Biosciences, Inc.
    Inventors: Rangarajan Sampath, Thomas A. Hall, David J. Ecker, Lawrence Blyn
  • Compositions for use in identification of bacteria
    Patent number: 8288523
    Abstract: The present invention provides compositions, kits and methods for rapid identification and quantification of bacteria by molecular mass and base composition analysis.
    Type: Grant
    Filed: March 7, 2007
    Date of Patent: October 16, 2012
    Assignee: Ibis Biosciences, Inc.
    Inventors: Rangarajan Sampath, Thomas A. Hall, David J. Ecker, Lawrence Blyn
  • COMPOSITIONS FOR USE IN IDENTIFICATION OF ALPHAVIRUSES
    Publication number: 20120244522
    Abstract: The present invention provides oligonucleotide primers and compositions and kits containing the same for rapid identification of alphaviruses by amplification of a segment of viral nucleic acid followed by molecular mass analysis.
    Type: Application
    Filed: February 20, 2012
    Publication date: September 27, 2012
    Applicant: IBIS BIOSCIENCES, INC.
    Inventors: Rangarajan Sampath, Thomas A. Hall, Mark W. Eshoo
  • Methods for identifying bioagents
    Patent number: 8268565
    Abstract: The present invention provides methods for rapid forensic analysis of mitochondrial DNA and methods for characterizing heteroplasmy of mitochondrial DNA, which can be used to assess the progression of mitochondrial diseases.
    Type: Grant
    Filed: December 2, 2008
    Date of Patent: September 18, 2012
    Assignee: Ibis Biosciences, Inc.
    Inventors: David J. Ecker, Richard H. Griffey, Rangarajan Sampath, Stephen A. Hofstadler, John McNeil, Stanley T. Crooke, Lawrence B. Blyn, Thomas A. Hall, Yun Jiang, James C. Hannis, Neill White, Vivek Samant, Mark W. Eshoo, Jared J. Drader
  • COMPOSITIONS FOR USE IN IDENTIFICATION OF ORTHOPOXVIRUSES
    Publication number: 20120208179
    Abstract: Oligonucleotide primers and compositions and kits containing the same for rapid identification of orthopoxviruses by amplification of a segment of viral nucleic acid followed by molecular mass analysis are provided.
    Type: Application
    Filed: April 19, 2012
    Publication date: August 16, 2012
    Applicant: IBIS BIOSCIENCES, INC.
    Inventors: Rangarajan Sampath, Thomas A. Hall, David J. Ecker, Steven A. Hofstadler
  • Compositions for use in identification of bacteria
    Patent number: 8242254
    Abstract: The present invention provides compositions, kits and methods for rapid identification and quantification of bacteria by molecular mass and base composition analysis.
    Type: Grant
    Filed: March 7, 2007
    Date of Patent: August 14, 2012
    Assignee: Ibis Biosciences, Inc.
    Inventors: Rangarajan Sampath, Thomas A. Hall, David J. Ecker, Lawrence Blyn
  • Composition For Use In Identification Of Bacteria
    Publication number: 20120171692
    Abstract: The present invention provides oligonucleotide primers and compositions and kits containing the same for rapid identification of bacteria by amplification of a segment of bacterial nucleic acid followed by molecular mass analysis.
    Type: Application
    Filed: October 30, 2007
    Publication date: July 5, 2012
    Applicant: Ibis Biosciences, Inc.
    Inventors: Sampath Rangarajan, Thomas A. Hall, David J. Ecker, Mark W. Eshoo, Christian Massire
  • METHODS FOR RAPID IDENTIFICATION OF PATHOGENS IN HUMANS AND ANIMALS
    Publication number: 20120164625
    Abstract: The present invention provides methods of: identifying pathogens in biological samples from humans and animals, resolving a plurality of etiologic agents present in samples obtained from humans and animals, determining detailed genetic information about such pathogens or etiologic agents, and rapid detection and identification of bioagents from environmental, clinical or other samples.
    Type: Application
    Filed: September 23, 2011
    Publication date: June 28, 2012
    Applicant: IBIS BIOSCIENCES, INC.
    Inventors: David J. Ecker, Richard H. Griffey, Rangarajan Sampath, Steven A. Hofstadler, John McNeil, Stanley T. Crooke, Lawrence Blyn, Ray Ranken, Thomas A. Hall
  • Methods for concurrent identification and quantification of an unknown bioagent
    Patent number: 8187814
    Abstract: The present invention provides methods for the quantification of an unknown bioagent in a sample by amplification of nucleic acid of the bioagent, and concurrent amplification of a known quantity of a calibration polynucleotide from which are obtained a bioagent identifying amplicon and a calibration amplicon. Upon molecular mass analysis, mass and abundance data are obtained. The identity of the bioagent is then determined from the molecular mass of the bioagent identifying amplicon and the quantity of the identified bioagent in the sample is determined from the abundance data of the bioagent identifying amplicon and the abundance data of the calibration amplicon.
    Type: Grant
    Filed: January 8, 2010
    Date of Patent: May 29, 2012
    Assignee: Ibis Biosciences, Inc.
    Inventors: David J. Ecker, Rangarajan Sampath, Lawrence B. Blyn, Steven A. Hofstadler, Thomas A. Hall
  • COMPOSITIONS FOR USE IN IDENTIFICATION OF BACTERIA
    Publication number: 20120122099
    Abstract: The present invention provides compositions, kits and methods for rapid identification and quantification of bacteria by molecular mass and base composition analysis.
    Type: Application
    Filed: March 7, 2007
    Publication date: May 17, 2012
    Inventors: Rangarajan Sampath, Thomas A. Hall, David J. Ecker, Lawrence Blyn
  • COMPOSITIONS FOR USE IN IDENTIFICATION OF BACTERIA
    Publication number: 20120122101
    Abstract: The present invention provides compositions, kits and methods for rapid identification and quantification of bacteria by molecular mass and base composition analysis.
    Type: Application
    Filed: March 7, 2007
    Publication date: May 17, 2012
    Inventors: Rangarajan Sampath, Thomas A. Hall, David J. Ecker, Lawrence Blyn
  • COMPOSITIONS FOR USE IN IDENTIFICATION OF BACTERIA
    Publication number: 20120122098
    Abstract: The present invention provides compositions, kits and methods for rapid identification and quantification of bacteria by molecular mass and base composition analysis.
    Type: Application
    Filed: March 7, 2007
    Publication date: May 17, 2012
    Inventors: Rangarajan Sampath, Thomas A. Hall, David J. Ecker, Lawrence Blyn
  • COMPOSITIONS FOR USE IN IDENTIFICATION OF BACTERIA
    Publication number: 20120122096
    Abstract: The present invention provides compositions, kits and methods for rapid identification and quantification of bacteria by molecular mass and base composition analysis.
    Type: Application
    Filed: March 7, 2007
    Publication date: May 17, 2012
    Inventors: Rangarajan Sampath, Thomas A. Hall, David J. Ecker, Lawrence Blyn
  • COMPOSITIONS FOR USE IN IDENTIFICATION OF BACTERIA
    Publication number: 20120122102
    Abstract: The present invention provides compositions, kits and methods for rapid identification and quantification of bacteria by molecular mass and base composition analysis.
    Type: Application
    Filed: March 7, 2007
    Publication date: May 17, 2012
    Inventors: Rangarajan Sampath, Thomas A. Hall, David J. Ecker, Lawrence Blyn
  • COMPOSITIONS FOR USE IN IDENTIFICATION OF BACTERIA
    Publication number: 20120122103
    Abstract: The present invention provides compositions, kits and methods for rapid identification and quantification of bacteria by molecular mass and base composition analysis.
    Type: Application
    Filed: March 7, 2007
    Publication date: May 17, 2012
    Inventors: Rangarajan Sampath, Thomas A. Hall, David J. Ecker, Lawrence Blyn
  • COMPOSITIONS FOR USE IN IDENTIFICATION OF BACTERIA
    Publication number: 20120122100
    Abstract: The present invention provides compositions, kits and methods for rapid identification and quantification of bacteria by molecular mass and base composition analysis.
    Type: Application
    Filed: March 7, 2007
    Publication date: May 17, 2012
    Inventors: Rangarajan Sampath, Thomas A. Hall, David J. Ecker, Lawrence Blyn