Patents by Inventor Thomas J. Burke

Thomas J. Burke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6618993
    Abstract: A railroad grade crossing assembly for blocking vehicle access across a railroad crossing including a gate assembly connectable to a stanchion and light assembly. This gate assembly is movable between a generally upright position to permit vehicle access across a railroad crossing and a generally horizontal position for blocking vehicle access across the railroad crossing. The gate assembly further includes a telescopic arm assembly for completely closing vehicle access to the railroad crossing. In another embodiment of the invention, the railroad grade crossing assembly includes a gate movable between a generally horizontal retracted position to permit vehicle access across a railroad crossing and a generally extended horizontal position for blocking vehicle access across a railroad crossing, the gate includes a telescopic arm for completely closing the railroad crossing, a first and second stanchions.
    Type: Grant
    Filed: March 19, 2001
    Date of Patent: September 16, 2003
    Inventor: Thomas J. Burke
  • Publication number: 20030044789
    Abstract: A rapid fluorescence polarization immunoassay (FPIA) for accurate quantification of any protein carrying an N-terminal polypeptide affinity tag especially a polyhistidine affinity tag (HisTag).
    Type: Application
    Filed: June 6, 2001
    Publication date: March 6, 2003
    Inventors: Thomas J. Burke, Robert Lowery, Karen Kleman-Leyer
  • Publication number: 20030036106
    Abstract: A method for quantitating enzyme activity that causes phosphorylation or dephosphorylation of a peptide or protein substrate is provided. The method utilizes the differences in the fluorescence polarization of a phosphorylated amino acid-containing fluorescence-emitting reporter molecule free in solution as compared to being bound to a binding molecule.
    Type: Application
    Filed: April 26, 2002
    Publication date: February 20, 2003
    Inventors: Thomas J. Burke, Randall E. Bolger, Rebecca Schall, Gregory Parker
  • Publication number: 20030027236
    Abstract: A method for quantitating enzyme activity of phosphorylation and dephosphorylation of a peptide or protein substrate, comprising measuring the fluorescence polarization of a fluorescence-emitting reporter molecule in solution with the phosphate. Then, adding an enzyme, either a kinase or a phosphatase, and incubating the solution. Finally, measuring the fluorescence polarization of the solution after the enzyme has had an opportunity to react with the peptide or protein substrate.
    Type: Application
    Filed: June 12, 2002
    Publication date: February 6, 2003
    Inventors: Thomas J. Burke, Randall E. Bolgeer, Rebecca Schall, Gregory Parker
  • Patent number: 6511815
    Abstract: The system comprises mixing a fluorescence-emitting compound that binds to the steroid hormone receptors in a solution containing the steroid hormone receptors. Then, measuring the fluorescence polarization of the solution. Subsequently, incubating the solution with at least one molecule that may compete with the compound for interaction with the steroid hormone receptors. Measuring the fluorescence polarization of the solution again. Finally, comparing the fluorescence polarization measurements to quantify any competitive interaction.
    Type: Grant
    Filed: December 20, 1999
    Date of Patent: January 28, 2003
    Assignee: PanVera LLC
    Inventors: Thomas J. Burke, Randall E. Bolger, Kerry M. Ervin, Robert G. Lowery, William J. Checovich
  • Publication number: 20020167637
    Abstract: An exemplary embodiment of the invention is a backlit liquid crystal display (LCD) monitor comprising a backlight assembly, a cooling assembly, a rear cover assembly and a controller. The controller monitors temperature and controls cooling accordingly. The controller also monitors bulb luminance and ad adjust bulb current accordingly. Faults are monitored and logged so that predictive repair before failure analysis may be performed.
    Type: Application
    Filed: February 21, 2002
    Publication date: November 14, 2002
    Inventors: Thomas J. Burke, Gary Elco, Bryan Gudrian
  • Publication number: 20020160848
    Abstract: An overswing alerting mechanism/swing monitoring device that a user can wear, for example on the wrist, hand or arm, that can determine swing formation, and that can display and/or store the determined swing information. As an option, the device includes a visual and/or audible indicator for alerting the user to an improper swinging motion.
    Type: Application
    Filed: April 25, 2002
    Publication date: October 31, 2002
    Inventor: Thomas J. Burke
  • Publication number: 20020146741
    Abstract: A method is provided for measuring competitive binding activity of molecules to nuclear receptors comprising mixing a fluorescence-emitting compound that specifically binds to steroid hormone receptors in a solution wherein the fluorescence-emitting compound is in concentration below the dissociation constant and the steroid hormone receptors are at or above the dissociation constant using fluorescence polarization.
    Type: Application
    Filed: July 30, 2001
    Publication date: October 10, 2002
    Inventors: Cale M. Halbleib, Kerry M. Ervin, Mohammed S. Shekhani, Robert G. Lowery, William J. Checovich, Thomas J. Burke
  • Publication number: 20020129552
    Abstract: A railroad grade crossing assembly for blocking vehicle access across a railroad crossing including a gate assembly connectable to a stanchion and light assembly. This gate assembly is movable between a generally upright position to permit vehicle access across a railroad crossing and a generally horizontal position for blocking vehicle access across the railroad crossing. The gate assembly further includes a telescopic arm assembly for completely closing vehicle access to the railroad crossing. In another embodiment of the invention, the railroad grade crossing assembly includes a gate means movable between a generally horizontal retracted position to permit vehicle access across a railroad crossing and a generally extended horizontal position for blocking vehicle access across a railroad crossing, the gate means includes a telescopic arm for completely closing the railroad crossing, a first and second stanchions.
    Type: Application
    Filed: March 19, 2001
    Publication date: September 19, 2002
    Inventor: Thomas J. Burke
  • Patent number: 6413167
    Abstract: A golf overswing alerting mechanism is provided which produces a visual and/or audible indicator for the purpose of alerting a golfer to an improper swinging movement of a golf club. The overswing alerting mechanism is housed entirely within the hollow opening of the golf club shaft or is accommodated in a housing that is detachably affixed to the golf club. In a preferred configuration, the alerting mechanism includes a sound generation assembly for generating an audible sound upon occurrence of the overswing condition; an energy generation member to provide electrical energy to the sound generation assembly, and a circuit closing member or accelerometer(s) detecting the occurrence of an overswing condition. The preferred mechanism further includes an LCD readout provided in the grip butt of the golf club grip which indicates to the golfer the speed of the golf club shaft.
    Type: Grant
    Filed: November 9, 1999
    Date of Patent: July 2, 2002
    Inventor: Thomas J. Burke
  • Publication number: 20020052246
    Abstract: A golf overswing alerting mechanism is provided which produces a visual and/or audible indicator for the purpose of alerting a golfer to an improper swinging movement of a golf club. The overswing alerting mechanism is housed entirely within the hollow opening of the golf club shaft or is accommodated in a housing that is detachably affixed to the golf club. In a preferred configuration, the alerting mechanism includes a sound generation assembly for generating an audible sound upon occurrence of the overswing condition; an energy generation member to provide electrical energy to the sound generation assembly, and a circuit closing member or accelerometer(s) detecting the occurrence of an overswing condition. The preferred mechanism further includes an LCD readout provided in the grip butt of the golf club grip which indicates to the golfer the speed of the golf club shaft.
    Type: Application
    Filed: November 9, 1999
    Publication date: May 2, 2002
    Inventor: THOMAS J BURKE
  • Patent number: 6348090
    Abstract: A dry film coating composition for forming a coating suspension for film coating nutritional supplements, pharmaceutical tablets, and the like, including tapica dextrin and a detackifier.
    Type: Grant
    Filed: September 14, 2000
    Date of Patent: February 19, 2002
    Assignee: BPSI Holdings, Inc.
    Inventors: Susan M. Grillo, Brian Korchok, Bruce Kinsey, Stuart C. Porter, George Reyes, Thomas J. Burke, Charles Cunningham
  • Publication number: 20010036806
    Abstract: An apparatus and method for cleaning fecal matter from the interior of an extracted animal intestine is disclosed. The apparatus has a horizontal tube member for supporting an intestine; support members attached to opposite sides of said tube member for supporting the side portions of a slit intestine; a transporter mounted below and adjacent to the bottom side of said tube for moving intestines from adjacent the distal end of said tube towards the proximal end; a cutting blade mounted above said tube member; and a plurality of nozzles arranged at transversely opposite sides of said tube member for directing fluid downwardly and about the top side of said pipe member. A method for cleaning animal intestines using such an apparatus is also disclosed.
    Type: Application
    Filed: July 2, 2001
    Publication date: November 1, 2001
    Applicant: M&P Chitlin Co., Inc.
    Inventor: Thomas J. Burke
  • Patent number: 6267808
    Abstract: A dry film coating composition used to make a bright white film coating for nutritional supplements, pharmaceutical tablets, and the like, comprises dextrose, an auxiliary film-former, and titanium dioxide. Optionally, but advantageously, the coating composition also ay include one or more of the following components: a plasticizer, a surfactant, a flow aid, and a preservative.
    Type: Grant
    Filed: January 5, 2001
    Date of Patent: July 31, 2001
    Assignee: BPSI Holdings, Inc.
    Inventors: Susan M. Grillo, Brian Korchok, Bruce Kinsey, Melanie Hartman, Stuart C. Porter, Rita Steffenino, George Reyes, Thomas J. Burke
  • Patent number: 6254470
    Abstract: An apparatus and method for cleaning fecal matter from the interior of an extracted animal intestine is disclosed. The apparatus has a horizontal tube member for supporting an intestine; support members attached to opposite sides of said tube member for supporting the side portions of a slit intestine; a transporter mounted below and adjacent to the bottom side of said tube for moving intestines from adjacent the distal end of said tube towards the proximal end; a cutting blade mounted above said tube member; and a plurality of nozzles arranged at transversely opposite sides of said tube member for directing fluid downwardly and about the top side of said pipe member. A method for cleaning animal intestines using such an apparatus is also disclosed.
    Type: Grant
    Filed: December 29, 1998
    Date of Patent: July 3, 2001
    Assignee: M&P Chitlin Co., Inc.
    Inventor: Thomas J. Burke
  • Publication number: 20010004522
    Abstract: A method for quantitating enzyme activity of phosphorylation and dephosphorylation of a peptide or protein substrate, comprising measuring the fluorescence polarization of a fluorescence-emitting reporter molecule in solution with the phosphate. Then, adding an enzyme, either a kinase or a phosphatase, and incubating the solution. Finally, measuring the fluorescence polarization of the solution after the enzyme has had an opportunity to react with the peptide or protein substrate.
    Type: Application
    Filed: October 28, 1997
    Publication date: June 21, 2001
    Inventors: THOMAS J. BURKE, RANDALL E. BOLGER, REBECCA SCHALL, GREGORY PARKER
  • Patent number: 6248391
    Abstract: A dry film coating composition used to make a bright white film coating for nutritional supplements, pharmaceutical tablets, and the like, comprises dextrose, an auxiliary film-former, and titanium dioxide. Optionally, but advantageously, the coating composition also may include one or more of the following components: a plasticizer, a surfactant, a flow aid, and a preservative.
    Type: Grant
    Filed: July 16, 1997
    Date of Patent: June 19, 2001
    Assignee: BPSI Holdings, Inc.
    Inventors: Susan M. Grillo, Brian Korchok, Bruce Kinsey, Melanie Hartman, Stuart C. Porter, Rita Steffenino, George Reyes, Thomas J. Burke
  • Patent number: 6183808
    Abstract: A dry film coating composition for forming a coating suspension for film coating nutritional supplements, pharmaceutical tablets, and the like, comprising a dextrin and a detackifier.
    Type: Grant
    Filed: January 2, 1998
    Date of Patent: February 6, 2001
    Assignee: BPSI Holdings, Inc.
    Inventors: Susan M. Grillo, Brian Korchok, Bruce Kinsey, Stuart C. Porter, George Reyes, Thomas J. Burke, Charles Cunningham
  • Patent number: 6100039
    Abstract: Described is a process for detecting reverse transcriptase activity and, thereby, reverse transcriptase inhibitors using fluorescence polarization, comprising, mixing a DNA primer with an RNA template. Then forming an RNA/DNA duplex utilizing the reverse transcriptase and removing the RNA from the RNA/DNA duplex to form single-stranded DNA. Finally, adding a fluorescent-labeled oligonucleotide complementary to the single-stranded DNA for hybridizing to the single-stranded DNA; and, measuring the fluorescence polarization.
    Type: Grant
    Filed: January 28, 1999
    Date of Patent: August 8, 2000
    Assignee: Panvera, Inc.
    Inventors: Thomas J. Burke, Randall E. Bolger, Francis J. Lenoch
  • Patent number: 6012988
    Abstract: A golf club with overswing alerting mechanism is provided which produces an audible sound upon the occurrence of an overswing condition. In this golf club, the overswing alerting mechanism is housed entirely within the hollow opening of the golf club shaft. This overswing alerting mechanism includes a sound generation assembly for generating an audible sound upon occurrence of the overswing condition; an energy generation member to provide electrical energy to the sound generation assembly, and a circuit closing member which closes the electrical circuit between the energy generation member and the sound generation assembly only upon the occurrence of an overswing condition.
    Type: Grant
    Filed: August 13, 1998
    Date of Patent: January 11, 2000
    Inventor: Thomas J. Burke