Patents by Inventor Thomas Knappe

Thomas Knappe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • VEGF Neutralizing Prodrugs for the Treatment of Ocular Conditions
    Publication number: 20150297740
    Abstract: The present invention relates to a pharmaceutical composition comprising one or more pharmaceutically acceptable excipient(s) and a VEGF neutralizing prodrug, which comprises a VEGF neutralizing biologically active moiety, for use in a method for the treatment of one or more ocular conditions.
    Type: Application
    Filed: October 8, 2013
    Publication date: October 22, 2015
    Inventors: Harald RAU, Thomas KNAPPE, Burkhardt Laufer, Romy REIMANN, Samuel WEISBROD, Kennett SPROGØE, Nicola BISEK, Sebastian STARK, Tobias VOIGT
  • Hydrogel Prodrugs
    Publication number: 20150258205
    Abstract: The present invention relates to a process for the preparation of a hydrogel and to a hydrogel obtainable by said process. The present invention further relates to a process for the preparation of a hydrogel-spacer conjugate, to a hydrogel-spacer conjugate obtainable by said process, to a process for the preparation of a carrier-linked prodrug and to carrier-linked prodrugs obtainable by said process, in particular to carrier-linked prodrugs that provide for a controlled or sustained release of a drug from a carrier. In addition, the invention relates to the use of the hydrogel for the preparation of a carrier-linked prodrug.
    Type: Application
    Filed: October 8, 2013
    Publication date: September 17, 2015
    Inventors: Harald Rau, Tobias Voigt, Burkhardt Laufer, Nicola Bisek, Franziska Hahn, Thomas Knappe
  • PREVENTION AND TREATMENT OF OCULAR CONDITIONS
    Publication number: 20150010634
    Abstract: The present invention relates to pharmaceutical compositions comprising hydrogel-linked prodrug for use in the treatment, prevention and/or diagnosis a condition of the eye and ophthalmic devices comprising said pharmaceutical compositions.
    Type: Application
    Filed: October 11, 2012
    Publication date: January 8, 2015
    Applicant: Ascendis Pharma Ophthamology Division A/S
    Inventors: Thomas Knappe, Burkhardt Laufer, Harald Rau, Kennett Sprogøe, Tobias Voigt, Samuel Weisbrod